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GB8403739D0 - Chemical compounds - Google Patents

Chemical compounds

Info

Publication number
GB8403739D0
GB8403739D0 GB848403739A GB8403739A GB8403739D0 GB 8403739 D0 GB8403739 D0 GB 8403739D0 GB 848403739 A GB848403739 A GB 848403739A GB 8403739 A GB8403739 A GB 8403739A GB 8403739 D0 GB8403739 D0 GB 8403739D0
Authority
GB
United Kingdom
Prior art keywords
group
branched
straight
hydrogen atom
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GB848403739A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roussel Laboratories Ltd
Original Assignee
Roussel Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Laboratories Ltd filed Critical Roussel Laboratories Ltd
Priority to GB848403739A priority Critical patent/GB8403739D0/en
Publication of GB8403739D0 publication Critical patent/GB8403739D0/en
Priority to KR1019850000879A priority patent/KR850005847A/en
Priority to ZA85696A priority patent/ZA85696B/en
Priority to EP85400219A priority patent/EP0153230B1/en
Priority to DE8585400219T priority patent/DE3571621D1/en
Priority to AT85400219T priority patent/ATE44745T1/en
Priority to NZ211104A priority patent/NZ211104A/en
Priority to JP60023706A priority patent/JPS60184086A/en
Priority to DK63385A priority patent/DK63385A/en
Priority to HU85529A priority patent/HU192318B/en
Priority to ES540332A priority patent/ES8702421A1/en
Priority to CA000474113A priority patent/CA1257259A/en
Priority to PT79955A priority patent/PT79955B/en
Priority to GB08503541A priority patent/GB2154583B/en
Priority to FI850582A priority patent/FI79323C/en
Priority to GR850369A priority patent/GR850369B/el
Priority to AU38672/85A priority patent/AU574131B2/en
Priority to ES553574A priority patent/ES8800243A1/en
Priority to US06/892,771 priority patent/US4762840A/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Luminescent Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Polymerisation Methods In General (AREA)
  • Indole Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

Compounds of formula I <IMAGE> [wherein R and R3,which may be the same or different, each represents a hydrogen atom or a straight or branched C1-6 alkyl group or together with the intervening carbon atom represent a C3-6 cycloalkyl group; R1 represents a hydroxy group, a straight or branched C1-6 alkoxy group or a group of formula <IMAGE> (wherein R5 and R6, which may be the same or different, each represents a hydrogen atom or a C1-6 alkyl group or together with the intervening nitrogen atom represent a piperidino or morpholino group); and R2 represents a hydrogen atom, a straight or branched C1-16 alkyl group, a C2-7 alkoxycarbonyl group, a C3-6 cycloalkyl group, an aralkyl group, an aryl group (unsubstituted or substituted by one or more halogen atoms or C1-6 alkyl, C1-6 alkoxy or nitro groups), or a heteroaryl group] and salts thereof are antiallergic agents.
GB848403739A 1984-02-13 1984-02-13 Chemical compounds Pending GB8403739D0 (en)

Priority Applications (19)

Application Number Priority Date Filing Date Title
GB848403739A GB8403739D0 (en) 1984-02-13 1984-02-13 Chemical compounds
KR1019850000879A KR850005847A (en) 1984-02-13 1985-01-13 Process for preparing pyrimido [2,1-b] benzothiazole and its salts
ZA85696A ZA85696B (en) 1984-02-13 1985-01-29 Pyrimido(2,1-b)benzothiazoles
EP85400219A EP0153230B1 (en) 1984-02-13 1985-02-11 Pyrimido(2,1-b)benzothiazole derivatives and their salts, process and preparation intermediates, their use as medicaments and compositions containing them
DE8585400219T DE3571621D1 (en) 1984-02-13 1985-02-11 Pyrimido(2,1-b)benzothiazole derivatives and their salts, process and preparation intermediates, their use as medicaments and compositions containing them
AT85400219T ATE44745T1 (en) 1984-02-13 1985-02-11 PYRIMIDO(2,1-B)BENZOTHIAZOLE DERIVATIVES AND THEIR SALTS, PROCESSES AND INTERMEDIATE PRODUCTS FOR THEIR MANUFACTURE, THEIR USE AS MEDICINAL PRODUCTS AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM.
GR850369A GR850369B (en) 1984-02-13 1985-02-12
DK63385A DK63385A (en) 1984-02-13 1985-02-12 PYRIMIDO (2,1-B) BENZOTHIAZOLES AND SALTS THEREOF, AND PROCEDURE FOR THEIR PREPARATION
GB08503541A GB2154583B (en) 1984-02-13 1985-02-12 Pyrimidobenzthiazoles
NZ211104A NZ211104A (en) 1984-02-13 1985-02-12 Pybenzothiazoles and pharmaceutical compositions
HU85529A HU192318B (en) 1984-02-13 1985-02-12 Process for preparing pyrimido/2,1-b/benzothiazole derivatives and pharmaceutical compositions containing such compounds as active substances
ES540332A ES8702421A1 (en) 1984-02-13 1985-02-12 Pyrimido(2,1-b)benzothiazole derivatives and their salts, process and preparation intermediates, their use as medicaments and compositions containing them.
CA000474113A CA1257259A (en) 1984-02-13 1985-02-12 Process for preparing pyrimido (2,1-b) benzothiazoles and salts thereof
PT79955A PT79955B (en) 1984-02-13 1985-02-12 Chemical compounds
JP60023706A JPS60184086A (en) 1984-02-13 1985-02-12 Compound
FI850582A FI79323C (en) 1984-02-13 1985-02-12 FREQUENCY REFRIGERATION FOR THERAPEUTIC THERAPY OF PYRIMIDO / 2,1-B / BENZODIAZOLER.
AU38672/85A AU574131B2 (en) 1984-02-13 1985-02-13 Pyrimido (2,1-b)benzothiazoles
ES553574A ES8800243A1 (en) 1984-02-13 1986-04-01 Pyrimido(2,1-b)benzothiazole derivatives and their salts, process and preparation intermediates, their use as medicaments and compositions containing them.
US06/892,771 US4762840A (en) 1984-02-13 1986-07-31 Pyrimido[2,1-b]benzothiazoles having antiallergic activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848403739A GB8403739D0 (en) 1984-02-13 1984-02-13 Chemical compounds

Publications (1)

Publication Number Publication Date
GB8403739D0 true GB8403739D0 (en) 1984-03-14

Family

ID=10556508

Family Applications (2)

Application Number Title Priority Date Filing Date
GB848403739A Pending GB8403739D0 (en) 1984-02-13 1984-02-13 Chemical compounds
GB08503541A Expired GB2154583B (en) 1984-02-13 1985-02-12 Pyrimidobenzthiazoles

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB08503541A Expired GB2154583B (en) 1984-02-13 1985-02-12 Pyrimidobenzthiazoles

Country Status (16)

Country Link
EP (1) EP0153230B1 (en)
JP (1) JPS60184086A (en)
KR (1) KR850005847A (en)
AT (1) ATE44745T1 (en)
AU (1) AU574131B2 (en)
CA (1) CA1257259A (en)
DE (1) DE3571621D1 (en)
DK (1) DK63385A (en)
ES (2) ES8702421A1 (en)
FI (1) FI79323C (en)
GB (2) GB8403739D0 (en)
GR (1) GR850369B (en)
HU (1) HU192318B (en)
NZ (1) NZ211104A (en)
PT (1) PT79955B (en)
ZA (1) ZA85696B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4762840A (en) * 1984-02-13 1988-08-09 Roussel Uclaf Pyrimido[2,1-b]benzothiazoles having antiallergic activity
GB8519261D0 (en) * 1985-07-31 1985-09-04 Roussel Lab Ltd Chemical compounds
SG186821A1 (en) 2010-07-02 2013-02-28 Gilead Sciences Inc 2 -quinolinyl- acetic acid derivatives as hiv antiviral compounds
EP2588450B1 (en) 2010-07-02 2017-05-24 Gilead Sciences, Inc. Napht-2-ylacetic acid derivatives to treat aids
SG194512A1 (en) * 2011-04-21 2013-12-30 Gilead Sciences Inc Benzothiazole compounds and their pharmaceutical use
WO2013103738A1 (en) 2012-01-04 2013-07-11 Gilead Sciences, Inc. Napthalene acetic acid derivatives against hiv infection
WO2013103724A1 (en) 2012-01-04 2013-07-11 Gilead Sciences, Inc. 2- (tert - butoxy) -2- (7 -methylquinolin- 6 - yl) acetic acid derivatives for treating aids
CA2850881C (en) 2012-04-20 2021-02-16 Gilead Sciences, Inc. Benzothiazol-6-yl acetic acid derivatives and their use for treating an hiv infection

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3919201A (en) * 1970-09-30 1975-11-11 Lilly Industries Ltd 2-({62 -Aminoacryloyl)iminobenzothiazolines
DE2810863A1 (en) * 1978-03-13 1979-09-27 Boehringer Mannheim Gmbh 1-OXO-1H-PYRIMIDO ANGLE CLAMP ON 6.1-B ANGLE CLAMP ON BENZTHIAZOLE DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF
GB8519261D0 (en) * 1985-07-31 1985-09-04 Roussel Lab Ltd Chemical compounds

Also Published As

Publication number Publication date
HU192318B (en) 1987-05-28
ES540332A0 (en) 1986-12-16
HUT38649A (en) 1986-06-30
PT79955A (en) 1985-03-01
GB2154583A (en) 1985-09-11
FI850582L (en) 1985-08-14
AU3867285A (en) 1985-08-22
ES8800243A1 (en) 1987-10-16
EP0153230A2 (en) 1985-08-28
GR850369B (en) 1985-06-14
FI79323C (en) 1989-12-11
GB8503541D0 (en) 1985-03-13
ES553574A0 (en) 1987-10-16
FI79323B (en) 1989-08-31
PT79955B (en) 1987-02-02
DE3571621D1 (en) 1989-08-24
NZ211104A (en) 1987-08-31
ATE44745T1 (en) 1989-08-15
DK63385D0 (en) 1985-02-12
ZA85696B (en) 1986-03-26
FI850582A0 (en) 1985-02-12
EP0153230B1 (en) 1989-07-19
EP0153230A3 (en) 1986-10-01
GB2154583B (en) 1987-10-28
KR850005847A (en) 1985-09-26
AU574131B2 (en) 1988-06-30
ES8702421A1 (en) 1986-12-16
CA1257259A (en) 1989-07-11
DK63385A (en) 1985-08-14
JPS60184086A (en) 1985-09-19

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