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GB2437799B - Defective interfering virus - Google Patents

Defective interfering virus

Info

Publication number
GB2437799B
GB2437799B GB0610342A GB0610342A GB2437799B GB 2437799 B GB2437799 B GB 2437799B GB 0610342 A GB0610342 A GB 0610342A GB 0610342 A GB0610342 A GB 0610342A GB 2437799 B GB2437799 B GB 2437799B
Authority
GB
United Kingdom
Prior art keywords
defective interfering
interfering virus
virus
defective
interfering
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
GB0610342A
Other versions
GB2437799A (en
GB0610342D0 (en
Inventor
Nigel Dimmock
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Warwick
Original Assignee
University of Warwick
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Warwick filed Critical University of Warwick
Priority to GB0610342A priority Critical patent/GB2437799B/en
Publication of GB0610342D0 publication Critical patent/GB0610342D0/en
Priority to CA2652595A priority patent/CA2652595C/en
Priority to ES07732910.0T priority patent/ES2527122T3/en
Priority to PL07732910T priority patent/PL2019685T3/en
Priority to AU2007253033A priority patent/AU2007253033B2/en
Priority to EP07732910.0A priority patent/EP2019685B1/en
Priority to DK07732910T priority patent/DK2019685T3/en
Priority to US12/302,194 priority patent/US8435508B2/en
Priority to CN2007800189100A priority patent/CN101454023B/en
Priority to PCT/GB2007/001889 priority patent/WO2007135420A2/en
Publication of GB2437799A publication Critical patent/GB2437799A/en
Application granted granted Critical
Publication of GB2437799B publication Critical patent/GB2437799B/en
Priority to US13/712,045 priority patent/US9089516B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04Inactivation or attenuation; Producing viral sub-units
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5252Virus inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/543Mucosal route intranasal
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
GB0610342A 2006-05-24 2006-05-24 Defective interfering virus Active GB2437799B (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
GB0610342A GB2437799B (en) 2006-05-24 2006-05-24 Defective interfering virus
DK07732910T DK2019685T3 (en) 2006-05-24 2007-05-24 Defective interfering virus
CN2007800189100A CN101454023B (en) 2006-05-24 2007-05-24 Defective interfering virus
PL07732910T PL2019685T3 (en) 2006-05-24 2007-05-24 Defective interfering virus
AU2007253033A AU2007253033B2 (en) 2006-05-24 2007-05-24 Defective interfering virus
EP07732910.0A EP2019685B1 (en) 2006-05-24 2007-05-24 Defective interfering virus
CA2652595A CA2652595C (en) 2006-05-24 2007-05-24 Defective interfering virus
US12/302,194 US8435508B2 (en) 2006-05-24 2007-05-24 Cloned defective interfering influenza A virus
ES07732910.0T ES2527122T3 (en) 2006-05-24 2007-05-24 Defective interfering virus
PCT/GB2007/001889 WO2007135420A2 (en) 2006-05-24 2007-05-24 Defective interfering virus
US13/712,045 US9089516B2 (en) 2006-05-24 2012-12-12 Method of preventing or treating influenza A viral infection using cloned DI influenza A viral particles

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0610342A GB2437799B (en) 2006-05-24 2006-05-24 Defective interfering virus

Publications (3)

Publication Number Publication Date
GB0610342D0 GB0610342D0 (en) 2006-07-05
GB2437799A GB2437799A (en) 2007-11-07
GB2437799B true GB2437799B (en) 2008-08-13

Family

ID=36687682

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0610342A Active GB2437799B (en) 2006-05-24 2006-05-24 Defective interfering virus

Country Status (2)

Country Link
CN (1) CN101454023B (en)
GB (1) GB2437799B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8435508B2 (en) 2006-05-24 2013-05-07 The University Of Warwick Cloned defective interfering influenza A virus
US8691215B2 (en) 2008-12-12 2014-04-08 The University Of Warwick Anti-viral protection with viruses containing defective genome segments

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2522615A (en) * 2014-01-16 2015-08-05 Univ Warwick Assay and medicament

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060057116A1 (en) * 1999-04-06 2006-03-16 Yoshihiro Kawaoka Recombinant influenza viruses for vaccines and gene therapy
WO2006051069A2 (en) * 2004-11-11 2006-05-18 Solvay Pharmaceuticals B.V. Defective influenza virus particles

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1451038A (en) * 1999-07-30 2003-10-22 埃西斯创新有限公司 Attenuated influenza virus useful as vaccine

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060057116A1 (en) * 1999-04-06 2006-03-16 Yoshihiro Kawaoka Recombinant influenza viruses for vaccines and gene therapy
WO2006051069A2 (en) * 2004-11-11 2006-05-18 Solvay Pharmaceuticals B.V. Defective influenza virus particles

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
J. Gen. Virol., Vol.87, 2006, Dimmock, N. J. et al., "In vivo antiviral activity...", pp.1259-1265 *
J. Virol. Methods, Vol.108, 2003, Duhaut, S. D. et al., "Defective influenza A virus...", pp.75-82 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8435508B2 (en) 2006-05-24 2013-05-07 The University Of Warwick Cloned defective interfering influenza A virus
US9089516B2 (en) 2006-05-24 2015-07-28 The University Of Warwick Method of preventing or treating influenza A viral infection using cloned DI influenza A viral particles
US8691215B2 (en) 2008-12-12 2014-04-08 The University Of Warwick Anti-viral protection with viruses containing defective genome segments

Also Published As

Publication number Publication date
GB2437799A (en) 2007-11-07
CN101454023A (en) 2009-06-10
CN101454023B (en) 2013-06-26
GB0610342D0 (en) 2006-07-05

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