GB2450454B - Terminating substrates for DNA polymerases - Google Patents
Terminating substrates for DNA polymerasesInfo
- Publication number
- GB2450454B GB2450454B GB0818768A GB0818768A GB2450454B GB 2450454 B GB2450454 B GB 2450454B GB 0818768 A GB0818768 A GB 0818768A GB 0818768 A GB0818768 A GB 0818768A GB 2450454 B GB2450454 B GB 2450454B
- Authority
- GB
- United Kingdom
- Prior art keywords
- dna polymerases
- terminating
- substrates
- terminating substrates
- polymerases
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 title 1
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 title 1
- 239000000758 substrate Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Saccharide Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI20065162A FI20065162A0 (en) | 2006-03-13 | 2006-03-13 | Terminating substrates for DNA polymerases |
| PCT/FI2007/050127 WO2007104834A1 (en) | 2006-03-13 | 2007-03-08 | Terminating substrates for dna polymerases |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| GB0818768D0 GB0818768D0 (en) | 2008-11-19 |
| GB2450454A GB2450454A (en) | 2008-12-24 |
| GB2450454B true GB2450454B (en) | 2011-04-13 |
Family
ID=36192007
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB0818768A Expired - Fee Related GB2450454B (en) | 2006-03-13 | 2007-03-08 | Terminating substrates for DNA polymerases |
Country Status (3)
| Country | Link |
|---|---|
| FI (1) | FI20065162A0 (en) |
| GB (1) | GB2450454B (en) |
| WO (1) | WO2007104834A1 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8354421B2 (en) | 2007-06-29 | 2013-01-15 | Korea Research Insitute Of Chemical Technology | HIV reverse transcriptase inhibitors |
| ES2533863T3 (en) | 2007-06-29 | 2015-04-15 | Korea Research Institute Of Chemical Technology | Novel HIV reverse transcriptase inhibitors |
| KR20100092960A (en) | 2007-12-21 | 2010-08-23 | 한국화학연구원 | Processes for preparing hiv reverse transcriptase inhibitors |
| EP3268358A1 (en) | 2015-03-13 | 2018-01-17 | Forma Therapeutics, Inc. | Alpha-cinnamide compounds and compositions as hdac8 inhibitors |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0251786A2 (en) * | 1986-07-02 | 1988-01-07 | E.I. Du Pont De Nemours And Company | Alkynylamino-nucleotides |
| EP0340675A2 (en) * | 1988-05-02 | 1989-11-08 | The Perkin-Elmer Corporation | Time-resolved fluorimetric detection of lanthanide labeled nucleotides |
| WO1990000623A1 (en) * | 1988-07-08 | 1990-01-25 | Wallac Oy | Multi-label time-resolved fluorescence analysis of nucleic acid sequences using lanthanide chelates |
| US5798210A (en) * | 1993-03-26 | 1998-08-25 | Institut Pasteur | Derivatives utilizable in nucleic acid sequencing |
| US6255475B1 (en) * | 1995-01-31 | 2001-07-03 | Marek Kwiatkowski | Chain terminators, the use thereof for nucleic acid sequencing and synthesis and a method of their preparation |
| US20050084451A1 (en) * | 2003-08-29 | 2005-04-21 | Wallac Oy | Novel chelating agents and chelates and their use |
| US20050181393A1 (en) * | 2003-12-18 | 2005-08-18 | Wallac Oy | Novel chelating agents and highly luminescent and stable chelates and their use |
-
2006
- 2006-03-13 FI FI20065162A patent/FI20065162A0/en not_active Application Discontinuation
-
2007
- 2007-03-08 GB GB0818768A patent/GB2450454B/en not_active Expired - Fee Related
- 2007-03-08 WO PCT/FI2007/050127 patent/WO2007104834A1/en active Application Filing
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0251786A2 (en) * | 1986-07-02 | 1988-01-07 | E.I. Du Pont De Nemours And Company | Alkynylamino-nucleotides |
| EP0340675A2 (en) * | 1988-05-02 | 1989-11-08 | The Perkin-Elmer Corporation | Time-resolved fluorimetric detection of lanthanide labeled nucleotides |
| WO1990000623A1 (en) * | 1988-07-08 | 1990-01-25 | Wallac Oy | Multi-label time-resolved fluorescence analysis of nucleic acid sequences using lanthanide chelates |
| US5798210A (en) * | 1993-03-26 | 1998-08-25 | Institut Pasteur | Derivatives utilizable in nucleic acid sequencing |
| US6255475B1 (en) * | 1995-01-31 | 2001-07-03 | Marek Kwiatkowski | Chain terminators, the use thereof for nucleic acid sequencing and synthesis and a method of their preparation |
| US20050084451A1 (en) * | 2003-08-29 | 2005-04-21 | Wallac Oy | Novel chelating agents and chelates and their use |
| US20050181393A1 (en) * | 2003-12-18 | 2005-08-18 | Wallac Oy | Novel chelating agents and highly luminescent and stable chelates and their use |
Also Published As
| Publication number | Publication date |
|---|---|
| FI20065162A0 (en) | 2006-03-13 |
| WO2007104834A1 (en) | 2007-09-20 |
| GB0818768D0 (en) | 2008-11-19 |
| GB2450454A (en) | 2008-12-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 20200308 |