GB2194790B - Intermediates useful for preparing antibacterial agents - Google Patents

Intermediates useful for preparing antibacterial agents

Info

Publication number: GB2194790B
Authority: GB; United Kingdom
Prior art keywords: antibacterial agents; intermediates useful; preparing antibacterial; preparing; intermediates
Prior art date: 1984-04-09
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

GB08721347A

Other versions

GB2194790A (en

GB8721347D0 (en

Inventor

Haruhiro Yamashita

Masahisa Oka

Takayuki Naito

Jun Okumura

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bristol Myers Co

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-04-09

Filing date

1987-09-10

Publication date

1988-10-05

1987-09-10 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1987-10-14 Publication of GB8721347D0 publication Critical patent/GB8721347D0/en

1988-03-16 Publication of GB2194790A publication Critical patent/GB2194790A/en

1988-10-05 Application granted granted Critical

1988-10-05 Publication of GB2194790B publication Critical patent/GB2194790B/en

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/78—Separation; Purification; Stabilisation; Use of additives
- C07C45/79—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cephalosporin Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

GB08721347A 1984-04-09 1987-09-10 Intermediates useful for preparing antibacterial agents Expired GB2194790B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US59794184A	1984-04-09	1984-04-09

Publications (3)

Publication Number	Publication Date
GB8721347D0 GB8721347D0 (en)	1987-10-14
GB2194790A GB2194790A (en)	1988-03-16
GB2194790B true GB2194790B (en)	1988-10-05

Family

ID=24393575

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
GB08508846A Expired GB2157293B (en)	1984-04-09	1985-04-04	Chemical compounds
GB08721347A Expired GB2194790B (en)	1984-04-09	1987-09-10	Intermediates useful for preparing antibacterial agents
GB08721346A Expired GB2194789B (en)	1984-04-09	1987-09-10	Antibacterial agent intermediates

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
GB08508846A Expired GB2157293B (en)	1984-04-09	1985-04-04	Chemical compounds

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
GB08721346A Expired GB2194789B (en)	1984-04-09	1987-09-10	Antibacterial agent intermediates

Country Status (31)

Country	Link
JP (4)	JPS615084A (en)
KR (1)	KR870002166B1 (en)
AR (1)	AR244694A1 (en)
AT (1)	AT388735B (en)
AU (2)	AU580990B2 (en)
BE (1)	BE902148A (en)
CA (3)	CA1276929C (en)
CH (1)	CH669197A5 (en)
DD (3)	DD236735A5 (en)
DE (1)	DE3512225A1 (en)
DK (1)	DK155985A (en)
ES (4)	ES8607318A1 (en)
FI (1)	FI84830C (en)
FR (1)	FR2563832B1 (en)
GB (3)	GB2157293B (en)
GR (1)	GR850883B (en)
HU (2)	HU204277B (en)
IE (2)	IE58408B1 (en)
IL (1)	IL74826A (en)
IT (1)	IT1190353B (en)
LU (1)	LU85840A1 (en)
MY (1)	MY101940A (en)
NL (1)	NL192925C (en)
NZ (1)	NZ211659A (en)
OA (1)	OA07985A (en)
PT (1)	PT80246B (en)
RU (1)	RU2056425C1 (en)
SE (4)	SE466205B (en)
SU (4)	SU1367858A3 (en)
YU (2)	YU46151B (en)
ZA (1)	ZA852236B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS61145186A (en) *	1984-12-20	1986-07-02	Meiji Seika Kaisha Ltd	Novel cephem compound and preparation thereof
US4708955A (en) *	1985-06-24	1987-11-24	Bristol-Myers Company	3-(substituted)propenyl-7-aminothiazol-ylcephalosporanic acids and esters thereof
DE3650157T2 (en) *	1985-12-26	1995-05-04	Eisai Co Ltd	CEPHALOSPORINE COMPOUNDS.
IL84128A (en) *	1986-10-13	1992-12-01	Eisai Co Ltd	3-propenylcephem derivatives, their preparation and pharmaceutical compositions containing them
AU614723B2 (en) *	1986-10-13	1991-09-12	Eisai Co. Ltd.	3-propenylcephem derivative
JPH085897B2 (en) *	1986-11-06	1996-01-24	エーザイ株式会社	3-propenyl cephem derivative
FR2622585B1 (en) *	1987-11-03	1991-04-19	Roussel Uclaf	NOVEL CEPHALOSPORINS COMPRISING IN POSITION 3 A SUBSTITUTED VINYL RADICAL, THEIR PREPARATION PROCESS, THEIR APPLICATION AS MEDICAMENTS, THE COMPOSITIONS CONTAINING THEM AND THE NEW INTERMEDIATES OBTAINED
JPH0699449B2 (en) *	1988-03-16	1994-12-07	エーザイ株式会社	Synthetic intermediate of cephem derivative
EP0612751A3 (en) *	1988-03-16	1994-09-21	Eisai Co Ltd	Compounds for the preparation of cephem derivatives.
FR2655042B1 (en) *	1989-11-29	1994-01-21	Adir Cie	NOVEL SUBSTITUTED BENZOTHIAZOLINONES, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
FR2663332B1 (en) *	1990-06-15	1997-11-07	Roussel Uclaf	NOVEL CEPHALOSPORINS COMPRISING IN POSITION 3 A RADICAL PROPENYL SUBSTITUTED BY A QUATERNARY AMMONIUM, THEIR PREPARATION PROCESS, THEIR APPLICATION AS MEDICAMENTS, THE COMPOSITIONS CONTAINING THEM AND THE NEW INTERMEDIATES OBTAINED.
US5126336A (en) *	1990-08-23	1992-06-30	Bristol-Myers Squibb Company	Antibiotic c-3 catechol-substituted cephalosporin compounds, compositions and method of use thereof
AT396108B (en) *	1991-08-21	1993-06-25	Biochemie Gmbh	NEW PROCESS AND NEW INTERMEDIATE PRODUCTS FOR THE PRODUCTION OF 7-AMINOCEPHALOSPORANIC ACID DERIVATIVES
JPH0741484A (en) *	1993-07-29	1995-02-10	Katayama Seiyakushiyo:Kk	Cephem compound and antimicrobial agent
KR100248851B1 (en) *	1994-08-16	2000-04-01	이치로 키타사토	New Cefem Derivatives
AU761450B2 (en)	1998-06-22	2003-06-05	Basilea Pharmaceutica Ag	Propenyl cephalosporin derivatives
JP4658806B2 (en)	2003-09-09	2011-03-23	日本化学工業株式会社	Method for producing 3-chloromethyl-3-cephem derivative

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1342241A (en) *	1970-01-23	1974-01-03	Glaxo Lab Ltd	Cephalosporin compounds
US4390534A (en) *	1978-12-29	1983-06-28	Fujisawa Pharmaceutical Co., Ltd.	Cephem and cepham compounds
EP0025017A1 (en) *	1979-08-28	1981-03-11	Ciba-Geigy Ag	Polyazathia compounds, process for their preparation, pharmaceutical preparations containing such compounds and use of the latter
US4409214A (en) *	1979-11-19	1983-10-11	Fujisawa Pharmaceutical, Co., Ltd.	7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
GR75644B (en) *	1980-06-18	1984-08-02	Fujisawa Pharmaceutical Co
GR78245B (en) *	1980-09-12	1984-09-26	Ciba Geigy Ag
US4521413A (en) *	1981-09-14	1985-06-04	Fujisawa Pharmaceutical Co., Ltd.	Cephem compounds
US4486586A (en) *	1983-02-10	1984-12-04	Bristol-Myers Company	Cephalosporin derivatives

1985
- 1985-02-14 CA CA000474260A patent/CA1276929C/en not_active Expired - Lifetime
- 1985-03-25 ZA ZA852236A patent/ZA852236B/en unknown
- 1985-04-02 AR AR85299945A patent/AR244694A1/en active
- 1985-04-02 NZ NZ211659A patent/NZ211659A/en unknown
- 1985-04-03 DD DD85274832A patent/DD236735A5/en unknown
- 1985-04-03 DE DE19853512225 patent/DE3512225A1/en active Granted
- 1985-04-03 SE SE8501680A patent/SE466205B/en not_active IP Right Cessation
- 1985-04-03 DK DK155985A patent/DK155985A/en not_active Application Discontinuation
- 1985-04-03 DD DD85287524A patent/DD249024A5/en unknown
- 1985-04-04 IE IE86685A patent/IE58408B1/en not_active IP Right Cessation
- 1985-04-04 FI FI851379A patent/FI84830C/en not_active IP Right Cessation
- 1985-04-04 OA OA58561A patent/OA07985A/en unknown
- 1985-04-04 NL NL8501002A patent/NL192925C/en not_active IP Right Cessation
- 1985-04-04 PT PT80246A patent/PT80246B/en unknown
- 1985-04-04 AU AU40862/85A patent/AU580990B2/en not_active Expired
- 1985-04-04 GB GB08508846A patent/GB2157293B/en not_active Expired
- 1985-04-04 CH CH1498/85A patent/CH669197A5/en not_active IP Right Cessation
- 1985-04-05 IL IL74826A patent/IL74826A/en not_active IP Right Cessation
- 1985-04-05 LU LU85840A patent/LU85840A1/en unknown
- 1985-04-05 FR FR8505281A patent/FR2563832B1/en not_active Expired
- 1985-04-05 AT AT0103985A patent/AT388735B/en not_active IP Right Cessation
- 1985-04-05 IT IT20267/85A patent/IT1190353B/en active
- 1985-04-08 GR GR850883A patent/GR850883B/el not_active IP Right Cessation
- 1985-04-08 RU SU853878102A patent/RU2056425C1/en active
- 1985-04-08 ES ES542013A patent/ES8607318A1/en not_active Expired
- 1985-04-09 JP JP60075233A patent/JPS615084A/en active Granted
- 1985-04-09 KR KR1019850002383A patent/KR870002166B1/en not_active Expired
- 1985-04-09 HU HU87151A patent/HU204277B/en unknown
- 1985-04-09 BE BE0/214810A patent/BE902148A/en not_active IP Right Cessation
- 1985-04-09 HU HU851299A patent/HU193750B/en unknown
- 1985-04-09 YU YU60085A patent/YU46151B/en unknown
- 1985-11-12 JP JP60252138A patent/JPS61143390A/en active Granted
- 1985-11-12 JP JP60252140A patent/JPS61143387A/en active Granted
- 1985-11-12 JP JP60252139A patent/JPS61143391A/en active Granted
1986
- 1986-01-31 ES ES551550A patent/ES8706155A1/en not_active Expired
- 1986-01-31 ES ES551551A patent/ES8706694A1/en not_active Expired
- 1986-02-06 SU SU864023036A patent/SU1367858A3/en active
- 1986-02-06 SU SU864019975A patent/SU1487814A3/en active
- 1986-02-06 SU SU864018257A patent/SU1375140A3/en active
- 1986-02-06 SU SU864020682A patent/SU1436882A3/en active
- 1986-03-03 DD DD86287525A patent/DD251752A5/en unknown
- 1986-09-10 ES ES557060A patent/ES8800949A1/en not_active Expired
1987
- 1987-06-25 YU YU118987A patent/YU46213B/en unknown
- 1987-09-10 GB GB08721347A patent/GB2194790B/en not_active Expired
- 1987-09-10 GB GB08721346A patent/GB2194789B/en not_active Expired
- 1987-10-01 MY MYPI87002761A patent/MY101940A/en unknown
1988
- 1988-11-11 AU AU25041/88A patent/AU610278B2/en not_active Expired
1989
- 1989-04-04 IE IE121089A patent/IE58403B1/en not_active IP Right Cessation
- 1989-04-06 SE SE8901225A patent/SE505256C2/en not_active IP Right Cessation
- 1989-04-06 SE SE8901224A patent/SE470259B/en not_active IP Right Cessation
- 1989-04-06 SE SE8901226A patent/SE470260B/en not_active IP Right Cessation
1991
- 1991-08-12 CA CA000616143A patent/CA1340638C/en not_active Expired - Fee Related
- 1991-08-21 CA CA000616144A patent/CA1340672C/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
AU4086285A (en)	1985-10-17
AU2504188A (en)	1989-03-02
JPH0350754B2 (en)	1991-08-02
FR2563832B1 (en)	1989-08-18
DK155985A (en)	1985-10-10
ATA103985A (en)	1989-01-15
DD251752A5 (en)	1987-11-25
SU1487814A3 (en)	1989-06-15
RU2056425C1 (en)	1996-03-20
SU1375140A3 (en)	1988-02-15
FR2563832A1 (en)	1985-11-08
JPH0262557B2 (en)	1990-12-26
ES8607318A1 (en)	1986-06-16
FI851379L (en)	1985-10-10
SU1436882A3 (en)	1988-11-07
AU580990B2 (en)	1989-02-09
SE8901225L (en)	1989-04-06
CA1276929C (en)	1990-11-27
ES8706694A1 (en)	1987-07-01
JPH0351716B2 (en)	1991-08-07
GB2194789A (en)	1988-03-16
GB2194789B (en)	1988-10-12
YU46151B (en)	1993-05-28
YU46213B (en)	1993-05-28
GR850883B (en)	1985-11-25
PT80246A (en)	1985-05-01
IT1190353B (en)	1988-02-16
MY101940A (en)	1992-02-15
IE850866L (en)	1985-10-09
SE8901226D0 (en)	1989-04-06
YU60085A (en)	1987-12-31
JPS615084A (en)	1986-01-10
HU204277B (en)	1991-12-30
SE8901226L (en)	1989-04-06
FI84830B (en)	1991-10-15
HU193750B (en)	1987-11-30
DE3512225A1 (en)	1985-10-17
AT388735B (en)	1989-08-25
GB2157293A (en)	1985-10-23
ES551550A0 (en)	1987-06-01
NZ211659A (en)	1988-11-29
SE505256C2 (en)	1997-07-21
JPH0357106B2 (en)	1991-08-30
KR850007424A (en)	1985-12-04
YU118987A (en)	1988-10-31
NL192925C (en)	1998-05-07
JPS61143391A (en)	1986-07-01
GB2194790A (en)	1988-03-16
GB8721347D0 (en)	1987-10-14
CA1340638C (en)	1999-07-06
ES542013A0 (en)	1986-06-16
SE8501680D0 (en)	1985-04-03
SE470259B (en)	1993-12-20
BE902148A (en)	1985-10-09
FI851379A0 (en)	1985-04-04
GB8508846D0 (en)	1985-05-09
SE466205B (en)	1992-01-13
ES8800949A1 (en)	1987-12-01
IT8520267A0 (en)	1985-04-05
IE58403B1 (en)	1993-09-22
GB8721346D0 (en)	1987-10-14
SE8901224L (en)	1989-04-06
SE8901224D0 (en)	1989-04-06
SE8901225D0 (en)	1989-04-06
OA07985A (en)	1987-01-31
PT80246B (en)	1987-10-20
IL74826A0 (en)	1985-07-31
DD249024A5 (en)	1987-08-26
DK155985D0 (en)	1985-04-03
AU610278B2 (en)	1991-05-16
GB2157293B (en)	1988-10-05
JPS61143387A (en)	1986-07-01
SE470260B (en)	1993-12-20
SU1367858A3 (en)	1988-01-15
HUT37622A (en)	1986-01-23
SE8501680L (en)	1985-10-10
ES551551A0 (en)	1987-07-01
AR244694A1 (en)	1993-11-30
NL192925B (en)	1998-01-05
FI84830C (en)	1992-01-27
ES8706155A1 (en)	1987-06-01
CA1340672C (en)	1999-07-20
LU85840A1 (en)	1985-12-16
IE58408B1 (en)	1993-09-22
DD236735A5 (en)	1986-06-18
KR870002166B1 (en)	1987-12-14
NL8501002A (en)	1985-11-01
DE3512225C2 (en)	1990-02-22
IL74826A (en)	1990-01-18
ES557060A0 (en)	1987-12-01
CH669197A5 (en)	1989-02-28
ZA852236B (en)	1985-11-27
JPS61143390A (en)	1986-07-01

Publication	Publication Date	Title
PH20942A (en)	1987-06-05	Antibacterial agents
PH23474A (en)	1989-08-07	Antibacterial agents
GB2194790B (en)	1988-10-05	Intermediates useful for preparing antibacterial agents
EP0164113A3 (en)	1987-01-28	Antibacterial compounds
PT79873A (en)	1985-02-01	Novel compounds
EP0160252A3 (en)	1987-01-14	Antibacterial compounds
DE3569675D1 (en)	1989-06-01	Implement for pre-skiing exercices
GB8705940D0 (en)	1987-04-15	Intermediates
DE3567868D1 (en)	1989-03-02	Naphthyridine antibacterial compounds
ZA854446B (en)	1986-04-30	Novel compounds
GB8416565D0 (en)	1984-08-01	Antibacterial derivatives
ZA85853B (en)	1986-09-24	Antibacterial agents
ZA857974B (en)	1986-08-27	Novel compounds
ZA859159B (en)	1986-11-26	Novel compounds
GB2204584B (en)	1992-01-29	Cyclobutenediones useful as intermediates
GB8516494D0 (en)	1985-07-31	Antibacterial derivatives
ZA852769B (en)	1985-11-27	Benzothiazolo-quinoline antibacterial compounds
IL76367A0 (en)	1986-01-31	Improved process for cephalsporin intermediates
GB8702275D0 (en)	1987-03-11	Intermediates for 1 2 4-triazolones
ZA855993B (en)	1986-03-26	Novel aminoalkylpenem compounds
ZA852802B (en)	1985-11-27	Benzoxazolo-quinoline antibacterial compounds
ZA853071B (en)	1985-12-24	Quino-quinoline antibacterial compounds
GB8718798D0 (en)	1987-09-16	Intermediates
GB8723294D0 (en)	1987-11-11	Antibacterial derivatives
GB2199032B (en)	1989-04-12	Eergoline derivatives useful as intermediates

Legal Events

Date	Code	Title	Description
2005-04-27	PE20	Patent expired after termination of 20 years	Effective date: 20050403