GB2013673A - New Cephalosporin Synthesis - Google Patents
New Cephalosporin SynthesisInfo
- Publication number
- GB2013673A GB2013673A GB7903347A GB7903347A GB2013673A GB 2013673 A GB2013673 A GB 2013673A GB 7903347 A GB7903347 A GB 7903347A GB 7903347 A GB7903347 A GB 7903347A GB 2013673 A GB2013673 A GB 2013673A
- Authority
- GB
- United Kingdom
- Prior art keywords
- new cephalosporin
- formula
- image
- cephalosporin synthesis
- synthesis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229930186147 Cephalosporin Natural products 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 229940124587 cephalosporin Drugs 0.000 title 1
- 150000001780 cephalosporins Chemical class 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- ATTZFSUZZUNHBP-UHFFFAOYSA-N Piperonyl sulfoxide Chemical compound CCCCCCCCS(=O)C(C)CC1=CC=C2OCOC2=C1 ATTZFSUZZUNHBP-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 125000001246 bromo group Chemical group Br* 0.000 abstract 1
- QHTOIDKCEPKVCM-ZCFIWIBFSA-N cepham Chemical compound S1CCCN2C(=O)C[C@H]21 QHTOIDKCEPKVCM-ZCFIWIBFSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002148 esters Chemical group 0.000 abstract 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical group II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 abstract 1
- 150000002730 mercury Chemical class 0.000 abstract 1
- 230000000269 nucleophilic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/02—Preparation
- C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Abstract
A process for the preparation of 3- exomethylene cepham sulphoxide of formula (I): <IMAGE> wherein R and R<1> are independently hydrogen or acyl and where R<2> is hydrogen or an ester protecting group, which process comprises treating a compound of formula (II): <IMAGE> where R, R<1> and R<2> are as previously defined and where X is bromine or iodine, with a mercury salt containing a non-nucleophilic anion.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7903347A GB2013673B (en) | 1977-12-24 | 1979-01-31 | Cephalosporin syntheis |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5389777 | 1977-12-24 | ||
| GB7903347A GB2013673B (en) | 1977-12-24 | 1979-01-31 | Cephalosporin syntheis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB2013673A true GB2013673A (en) | 1979-08-15 |
| GB2013673B GB2013673B (en) | 1982-06-03 |
Family
ID=26267363
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB7903347A Expired GB2013673B (en) | 1977-12-24 | 1979-01-31 | Cephalosporin syntheis |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB2013673B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0351121A3 (en) * | 1988-07-12 | 1991-09-18 | Jack Edward Baldwin | Process for producing exomethylene cepham compounds |
-
1979
- 1979-01-31 GB GB7903347A patent/GB2013673B/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0351121A3 (en) * | 1988-07-12 | 1991-09-18 | Jack Edward Baldwin | Process for producing exomethylene cepham compounds |
| JP2735297B2 (en) | 1988-07-12 | 1998-04-02 | エドワード ボルドウィン ジャック | Production of intermediates |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2013673B (en) | 1982-06-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES477695A1 (en) | Derivatives of dehydrocyclicimino acids | |
| IL49552A (en) | Adhesive compositions | |
| PT67803A (en) | Process for combating microorganisms namely through the use of new phtahalocyanine compounds | |
| AU531378B2 (en) | Cache for overlap of instruction fetch operations | |
| DE3262698D1 (en) | Antifibrinolytically active compounds | |
| SE7602144L (en) | QUATER IMIDAZOLIUM ASSOCIATIONS | |
| ES485098A1 (en) | Dibenzothiepin derivatives and a process for producing the same | |
| GR852867B (en) | ||
| GB2017087A (en) | Process for the preparation of xanthone derivatives | |
| GB2013673A (en) | New Cephalosporin Synthesis | |
| GB2005246A (en) | beta -Lactam compounds and processes for their preparation | |
| ES438430A1 (en) | Certain antiinflammatory dihydrobenzofuran and dihydronaphthofuran acetic acid compounds | |
| ES449068A1 (en) | Isoxazole derivatives | |
| GB2019843A (en) | N-Alkenylmoranoline derivatives | |
| ES471267A1 (en) | Lower alkyl 2-tri-(lower)alkylsilylacetylene-N-carbethoxyglycinates and process for using same | |
| IE791781L (en) | 4, 5-methano-bufadienolide rhamnosides | |
| SE7708452L (en) | COMPOSITION CONTAINING AN ANTHRAKINON COMPOUND | |
| GB2021588A (en) | Bibenzyl Derivatives, the Preparation thereof and Pharmaceutical Compositions Containing them | |
| AU548803B2 (en) | New n-substituted polyglycidyl urazole compounds, processes for their production and pharmaceutical preparations | |
| GB2017103A (en) | Cephalosporin analogues | |
| ZA80524B (en) | Process for the stabilization of novel halogenating compound | |
| DE3268984D1 (en) | Imidazolylcarboxylic acids, their derivatives and production | |
| ES478210A1 (en) | A procedure for preparing derivatives of xantona. (Machine-translation by Google Translate, not legally binding) | |
| JPS5283869A (en) | Cephalosporin compounds | |
| JPS5416466A (en) | Novel 3-hydroxypyrrolldine-3-carboxylic derivative |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PE20 | Patent expired after termination of 20 years |
Effective date: 19990130 |