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GB1385649A - Preparation of benzodiazepines - Google Patents

Preparation of benzodiazepines

Info

Publication number
GB1385649A
GB1385649A GB1315273A GB1315273A GB1385649A GB 1385649 A GB1385649 A GB 1385649A GB 1315273 A GB1315273 A GB 1315273A GB 1315273 A GB1315273 A GB 1315273A GB 1385649 A GB1385649 A GB 1385649A
Authority
GB
United Kingdom
Prior art keywords
benzodiazepines
formula
preparation
alkaryl
march
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1315273A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmedical SA Lab
Original Assignee
Pharmedical SA Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmedical SA Lab filed Critical Pharmedical SA Lab
Publication of GB1385649A publication Critical patent/GB1385649A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/28—Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

1385649 Benzodiazepines LABORATOIRES PHARMEDICAL SA 19 March 1973 [17 March 1972] 13152/73 Heading C2C Compounds of the general formula (R<SP>1</SP>=H, C 1-3 alkyl, alkaryl, aryl; R<SP>2,3</SP>=H, halogen, C 1-3 alkyl, alkaryl, alkoxy, NO 2 , sulphonic, sulphamido; Y = CO, CH 2 ) are prepared by reacting a compound of the formula (X = halogen) with a compound of the formula (Z = blocking group). Reference has been directed by the Comptroller to Specification 1,017,276.
GB1315273A 1972-03-17 1973-03-19 Preparation of benzodiazepines Expired GB1385649A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AR24101272 1972-03-17

Publications (1)

Publication Number Publication Date
GB1385649A true GB1385649A (en) 1975-02-26

Family

ID=3462398

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1315273A Expired GB1385649A (en) 1972-03-17 1973-03-19 Preparation of benzodiazepines

Country Status (4)

Country Link
JP (1) JPS4911894A (en)
BE (1) BE794358A (en)
CH (1) CH579543A5 (en)
GB (1) GB1385649A (en)

Also Published As

Publication number Publication date
CH579543A5 (en) 1976-09-15
BE794358A (en) 1973-05-16
JPS4911894A (en) 1974-02-01

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee