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GB0309397D0 - Screening methods - Google Patents

Screening methods

Info

Publication number
GB0309397D0
GB0309397D0 GB0309397A GB0309397A GB0309397D0 GB 0309397 D0 GB0309397 D0 GB 0309397D0 GB 0309397 A GB0309397 A GB 0309397A GB 0309397 A GB0309397 A GB 0309397A GB 0309397 D0 GB0309397 D0 GB 0309397D0
Authority
GB
United Kingdom
Prior art keywords
screening methods
screening
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB0309397A
Other versions
GB2400851B (en
GB2400851A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioinvent International AB
Original Assignee
Bioinvent International AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioinvent International AB filed Critical Bioinvent International AB
Priority to GB0309397A priority Critical patent/GB2400851B/en
Publication of GB0309397D0 publication Critical patent/GB0309397D0/en
Priority to PCT/EP2004/004387 priority patent/WO2004097041A2/en
Publication of GB2400851A publication Critical patent/GB2400851A/en
Application granted granted Critical
Publication of GB2400851B publication Critical patent/GB2400851B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/005—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Virology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Information Retrieval, Db Structures And Fs Structures Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
GB0309397A 2003-04-25 2003-04-25 Identifying binding of a polypeptide to a polypeptide target Expired - Fee Related GB2400851B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GB0309397A GB2400851B (en) 2003-04-25 2003-04-25 Identifying binding of a polypeptide to a polypeptide target
PCT/EP2004/004387 WO2004097041A2 (en) 2003-04-25 2004-04-23 Screening method for binding molecules

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0309397A GB2400851B (en) 2003-04-25 2003-04-25 Identifying binding of a polypeptide to a polypeptide target

Publications (3)

Publication Number Publication Date
GB0309397D0 true GB0309397D0 (en) 2003-06-04
GB2400851A GB2400851A (en) 2004-10-27
GB2400851B GB2400851B (en) 2004-12-15

Family

ID=9957209

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0309397A Expired - Fee Related GB2400851B (en) 2003-04-25 2003-04-25 Identifying binding of a polypeptide to a polypeptide target

Country Status (2)

Country Link
GB (1) GB2400851B (en)
WO (1) WO2004097041A2 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7601351B1 (en) 2002-06-26 2009-10-13 Human Genome Sciences, Inc. Antibodies against protective antigen
WO2004003144A2 (en) 2002-07-01 2004-01-08 Human Genome Sciences, Inc. Antibodies that specifically bind to reg iv
EP3050963B1 (en) 2005-03-31 2019-09-18 Chugai Seiyaku Kabushiki Kaisha Process for production of polypeptide by regulation of assembly
DK1876236T3 (en) * 2005-04-08 2014-10-20 Chugai Pharmaceutical Co Ltd Antibody as a functional replacement for blood coagulation factor VIII
CN105177091A (en) 2006-03-31 2015-12-23 中外制药株式会社 Antibody modification method for purifying bispecific antibody
CA2647846C (en) 2006-03-31 2016-06-21 Chugai Seiyaku Kabushiki Kaisha Methods for controlling blood pharmacokinetics of antibodies
CN106519025B (en) 2007-09-26 2021-04-23 中外制药株式会社 Method for changing isoelectric point of antibody by using amino acid substitution of CDR
WO2011123857A1 (en) * 2010-04-02 2011-10-06 Kalobios Pharmaceuticals, Inc. Generation of antibodies to an epitope of interest
RU2620071C2 (en) 2010-11-17 2017-05-22 Чугаи Сеияку Кабушики Каиша Multispecific antigen-binding molecule with alternate function to blood coagulation factor viii function
CN105764922B (en) 2013-09-27 2020-07-17 中外制药株式会社 Preparation method of polypeptide heteromultimer
TWI701435B (en) 2014-09-26 2020-08-11 日商中外製藥股份有限公司 Method to determine the reactivity of FVIII
MA40764A (en) 2014-09-26 2017-08-01 Chugai Pharmaceutical Co Ltd THERAPEUTIC AGENT INDUCING CYTOTOXICITY
TWI700300B (en) 2014-09-26 2020-08-01 日商中外製藥股份有限公司 Antibodies that neutralize substances with the function of FVIII coagulation factor (FVIII)
WO2016159213A1 (en) 2015-04-01 2016-10-06 中外製薬株式会社 Method for producing polypeptide hetero-oligomer
EP3395835B1 (en) 2015-12-25 2021-02-03 Chugai Seiyaku Kabushiki Kaisha Antibody having enhanced activity, and method for modifying same
CA3004288C (en) 2015-12-28 2025-05-27 Chugai Seiyaku Kabushiki Kaisha Method for promoting efficiency of purification of fc region-containing polypeptide
TWI820000B (en) 2016-04-28 2023-11-01 日商中外製藥股份有限公司 Antibody-containing preparations
JP7125932B2 (en) 2016-09-06 2022-08-25 中外製薬株式会社 Methods of Using Bispecific Antibodies Recognizing Coagulation Factor IX and/or Activated Coagulation Factor IX and Coagulation Factor X and/or Activated Coagulation Factor X
EP3690050A4 (en) 2017-09-29 2021-06-16 Chugai Seiyaku Kabushiki Kaisha MULTISPECIFIC ANTIGEN-BINDING MOLECULE HAVING SUBSTITUTION ACTIVITY FOR THE FUNCTION OF BLOOD COAGULATION FACTOR VIII COFACTOR (FVIII), AND PHARMACEUTICAL FORMULATION CONTAINING THE SAME MOLECULE AS ACTIVE PRINCIPLE
AR113816A1 (en) 2017-11-01 2020-06-17 Chugai Pharmaceutical Co Ltd VARIANTS AND ISOFORMS OF ANTIBODIES WITH REDUCED BIOLOGICAL ACTIVITY

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4778751A (en) * 1986-05-12 1988-10-18 Diagnostic Products Corporation Method for measuring antigens or antibodies in biological fluids using ligand labeled antigens or ligand labeled antibodies
SE9304060D0 (en) * 1993-12-06 1993-12-06 Bioinvent Int Ab Methods to select specific bacteriophages
GB0008419D0 (en) * 2000-04-05 2000-05-24 Bioinvent Int Ab A method for invitro molecular evolution of antibody function
US6653067B1 (en) * 2001-02-22 2003-11-25 Isis Pharmaceuticals, Inc. Methods for identifying ligand binding sites in a biomolecule

Also Published As

Publication number Publication date
WO2004097041A3 (en) 2005-02-03
WO2004097041A2 (en) 2004-11-11
GB2400851B (en) 2004-12-15
GB2400851A (en) 2004-10-27

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20070425