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FR3106005B1 - Capteur de concentration d’especes en milieu liquide offrant une resolution augmentee - Google Patents

Capteur de concentration d’especes en milieu liquide offrant une resolution augmentee Download PDF

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Publication number
FR3106005B1
FR3106005B1 FR2000129A FR2000129A FR3106005B1 FR 3106005 B1 FR3106005 B1 FR 3106005B1 FR 2000129 A FR2000129 A FR 2000129A FR 2000129 A FR2000129 A FR 2000129A FR 3106005 B1 FR3106005 B1 FR 3106005B1
Authority
FR
France
Prior art keywords
liquid medium
concentration sensor
increased resolution
species concentration
species
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR2000129A
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English (en)
Other versions
FR3106005A1 (fr
Inventor
Sébastien Hentz
Thomas Alava
Ivan Favero
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Universite Paris Cite
Original Assignee
Centre National de la Recherche Scientifique CNRS
Commissariat a lEnergie Atomique CEA
Universite de Paris
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, Commissariat a lEnergie Atomique CEA, Universite de Paris, Commissariat a lEnergie Atomique et aux Energies Alternatives CEA filed Critical Centre National de la Recherche Scientifique CNRS
Priority to FR2000129A priority Critical patent/FR3106005B1/fr
Priority to PCT/FR2021/050022 priority patent/WO2021140302A1/fr
Priority to US17/791,182 priority patent/US20230081434A1/en
Publication of FR3106005A1 publication Critical patent/FR3106005A1/fr
Application granted granted Critical
Publication of FR3106005B1 publication Critical patent/FR3106005B1/fr
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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0883—Serpentine channels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0433—Moving fluids with specific forces or mechanical means specific forces vibrational forces

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

Capteur de concentration d’au moins une espèce biologique dans le sang comportant un support (2), au moins un guide d’onde (4), un résonateur optomécanique (6) suspendu au support (2), ledit résonateur optomécanique (6) étant couplé optiquement au guide d’onde (4), ledit résonateur optomécanique étant configuré pour vibrer en mode de volume et comportant au moins une face s’étendant dans le plan du capteur et configurée pour recevoir des molécules de ladite espèce donnée, au moins ladite face comportant une couche de fonctionnalisation spécifique à ladite espèce, ledit résonateur optomécanique présentant une dimensions faible dans une direction normale au plan du capteur par rapport aux dimensions de ladite face. Figure pour l’abrégé : 1A
FR2000129A 2020-01-08 2020-01-08 Capteur de concentration d’especes en milieu liquide offrant une resolution augmentee Active FR3106005B1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FR2000129A FR3106005B1 (fr) 2020-01-08 2020-01-08 Capteur de concentration d’especes en milieu liquide offrant une resolution augmentee
PCT/FR2021/050022 WO2021140302A1 (fr) 2020-01-08 2021-01-08 Capteur pour détecter un analyte cible dans un milieu liquide avec un résonateur optique couplé à un résonateur mecanique
US17/791,182 US20230081434A1 (en) 2020-01-08 2021-01-08 Sensor for detecting a target analyte in a liquid medium with an optical resonator coupled to a mechanical resonator

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR2000129 2020-01-08
FR2000129A FR3106005B1 (fr) 2020-01-08 2020-01-08 Capteur de concentration d’especes en milieu liquide offrant une resolution augmentee

Publications (2)

Publication Number Publication Date
FR3106005A1 FR3106005A1 (fr) 2021-07-09
FR3106005B1 true FR3106005B1 (fr) 2024-04-26

Family

ID=70228198

Family Applications (1)

Application Number Title Priority Date Filing Date
FR2000129A Active FR3106005B1 (fr) 2020-01-08 2020-01-08 Capteur de concentration d’especes en milieu liquide offrant une resolution augmentee

Country Status (3)

Country Link
US (1) US20230081434A1 (fr)
FR (1) FR3106005B1 (fr)
WO (1) WO2021140302A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3130845B1 (fr) * 2021-12-16 2025-10-31 Commissariat Energie Atomique Dispositif de séquençage d’une sequence de nucleotides présentant une sensibilité augmentée et une fiabilité améliorée

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3733866B1 (fr) * 2010-11-05 2023-11-15 Genalyte, Inc. Systèmes de détection d'analytes optiques et procédés d'utilisation
US9869669B2 (en) * 2012-05-07 2018-01-16 Stc.Unm Biomarker sensing based on nanofluidic amplification and resonant optical detection
DE102017221952B3 (de) * 2017-12-05 2019-01-03 Karlsruher Institut für Technologie Mikro-optomechanisches System und Verfahren zu seiner Herstellung

Also Published As

Publication number Publication date
WO2021140302A1 (fr) 2021-07-15
US20230081434A1 (en) 2023-03-16
FR3106005A1 (fr) 2021-07-09

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