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FR3061714B1 - Complexes de lanthanides a base de dendrimeres - Google Patents

Complexes de lanthanides a base de dendrimeres Download PDF

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Publication number
FR3061714B1
FR3061714B1 FR1750245A FR1750245A FR3061714B1 FR 3061714 B1 FR3061714 B1 FR 3061714B1 FR 1750245 A FR1750245 A FR 1750245A FR 1750245 A FR1750245 A FR 1750245A FR 3061714 B1 FR3061714 B1 FR 3061714B1
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FR
France
Prior art keywords
dendrimer
formula
lanthanide complexes
based lanthanide
complexes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR1750245A
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English (en)
Other versions
FR3061714A1 (fr
Inventor
Stephane Petoud
Svetlana ELISEEVA
Ivana Martinic
Virginie PLACIDE
Franck Suzenet
Regis Delatouche
Joan LECLERC
Alexandra Foucault-Collet
Guillaume COLLET
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Universite d Orleans UFR de Sciences
Original Assignee
Centre National de la Recherche Scientifique CNRS
Universite d Orleans UFR de Sciences
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Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, Universite d Orleans UFR de Sciences filed Critical Centre National de la Recherche Scientifique CNRS
Priority to FR1750245A priority Critical patent/FR3061714B1/fr
Priority to US16/477,103 priority patent/US20190352511A1/en
Priority to PCT/EP2018/050510 priority patent/WO2018130542A1/fr
Priority to EP18700278.7A priority patent/EP3568401A1/fr
Publication of FR3061714A1 publication Critical patent/FR3061714A1/fr
Application granted granted Critical
Publication of FR3061714B1 publication Critical patent/FR3061714B1/fr
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    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
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    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0028—Oxazine dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0054—Macromolecular compounds, i.e. oligomers, polymers, dendrimers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
    • C08G83/002—Dendritic macromolecules
    • C08G83/003—Dendrimers
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    • C09B23/0066—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain being part of a carbocyclic ring,(e.g. benzene, naphtalene, cyclohexene, cyclobutenene-quadratic acid)
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Abstract

La présente invention concerne un complexe comprenant au moins un dendrimère et au moins un lanthanide, dans lequel le dendrimère comprend un motif de formule (I) suivante : dans laquelle : - C1 est un groupe de valence 4 de formule >N-CH2-CH2-N< ; - A1, A2 et A3 sont des groupes de formule -(CH2)2-C(O)-NH-(CH2)2- ; ledit motif de formule (I) étant relié de façon covalente à au moins une antenne qui absorbe à une longueur d'onde allant de 500 nm à 900 nm.
FR1750245A 2017-01-11 2017-01-11 Complexes de lanthanides a base de dendrimeres Expired - Fee Related FR3061714B1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
FR1750245A FR3061714B1 (fr) 2017-01-11 2017-01-11 Complexes de lanthanides a base de dendrimeres
US16/477,103 US20190352511A1 (en) 2017-01-11 2018-01-10 Lanthanide complexes comprising dendrimers
PCT/EP2018/050510 WO2018130542A1 (fr) 2017-01-11 2018-01-10 Complexes de lanthanides à base de dendrimères
EP18700278.7A EP3568401A1 (fr) 2017-01-11 2018-01-10 Complexes de lanthanides à base de dendrimères

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1750245 2017-01-11
FR1750245A FR3061714B1 (fr) 2017-01-11 2017-01-11 Complexes de lanthanides a base de dendrimeres

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FR3061714A1 FR3061714A1 (fr) 2018-07-13
FR3061714B1 true FR3061714B1 (fr) 2020-02-14

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FR1750245A Expired - Fee Related FR3061714B1 (fr) 2017-01-11 2017-01-11 Complexes de lanthanides a base de dendrimeres

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US (1) US20190352511A1 (fr)
EP (1) EP3568401A1 (fr)
FR (1) FR3061714B1 (fr)
WO (1) WO2018130542A1 (fr)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3125632B1 (fr) 2021-07-22 2024-10-04 Aledia Empilement de matériaux à effet d’antenne et dispositif optoélectronique comprenant un tel empilement

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7141676B1 (en) * 1996-02-08 2006-11-28 University Of Washington Water soluble multi-biotin-containing compounds

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Publication number Publication date
FR3061714A1 (fr) 2018-07-13
US20190352511A1 (en) 2019-11-21
WO2018130542A1 (fr) 2018-07-19
EP3568401A1 (fr) 2019-11-20

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