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FR2914920B1 - Procede de deacetalisation d'alpha-aminoacetals. - Google Patents

Procede de deacetalisation d'alpha-aminoacetals.

Info

Publication number
FR2914920B1
FR2914920B1 FR0702633A FR0702633A FR2914920B1 FR 2914920 B1 FR2914920 B1 FR 2914920B1 FR 0702633 A FR0702633 A FR 0702633A FR 0702633 A FR0702633 A FR 0702633A FR 2914920 B1 FR2914920 B1 FR 2914920B1
Authority
FR
France
Prior art keywords
aminoacetals
alpha
deacetalizing
protected alpha
deacetization
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0702633A
Other languages
English (en)
Other versions
FR2914920A1 (fr
Inventor
Muriel Albalat
Geraldine Primazot
Didier Wilhelm
Jean-Claude Vallejos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Clariant Speciality Fine Chemicals France
Original Assignee
Clariant Speciality Fine Chemicals France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0702633A priority Critical patent/FR2914920B1/fr
Application filed by Clariant Speciality Fine Chemicals France filed Critical Clariant Speciality Fine Chemicals France
Priority to US12/595,469 priority patent/US8609882B2/en
Priority to DK08718382.8T priority patent/DK2137139T3/en
Priority to CN200880017370.9A priority patent/CN101679223B/zh
Priority to CA2683612A priority patent/CA2683612C/fr
Priority to PCT/EP2008/053899 priority patent/WO2008125486A1/fr
Priority to JP2010502489A priority patent/JP5554698B2/ja
Priority to ES08718382.8T priority patent/ES2525372T3/es
Priority to RU2009141621/04A priority patent/RU2477270C2/ru
Priority to EP08718382.8A priority patent/EP2137139B1/fr
Publication of FR2914920A1 publication Critical patent/FR2914920A1/fr
Application granted granted Critical
Publication of FR2914920B1 publication Critical patent/FR2914920B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/18—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by doubly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/04—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups from amines with formation of carbamate groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/16—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne un procédé de préparation d'alpha-aminoaldéhydes N-protégés par déacétalisation de la fonction acétal d'alpha-aminoacétals N-protégés correspondants à l'aide d'acide formique.
FR0702633A 2007-04-11 2007-04-11 Procede de deacetalisation d'alpha-aminoacetals. Expired - Fee Related FR2914920B1 (fr)

Priority Applications (10)

Application Number Priority Date Filing Date Title
FR0702633A FR2914920B1 (fr) 2007-04-11 2007-04-11 Procede de deacetalisation d'alpha-aminoacetals.
RU2009141621/04A RU2477270C2 (ru) 2007-04-11 2008-04-02 СПОСОБ ДЕАЦЕТИЛИРОВАНИЯ α-АМИНОАЦЕТАЛЕЙ
CN200880017370.9A CN101679223B (zh) 2007-04-11 2008-04-02 α氨基缩醛的脱缩醛法
CA2683612A CA2683612C (fr) 2007-04-11 2008-04-02 Procede de desacetalisation d'alpha-aminoacetals
PCT/EP2008/053899 WO2008125486A1 (fr) 2007-04-11 2008-04-02 Procédé de désacétalisation d'alpha-aminoacétals
JP2010502489A JP5554698B2 (ja) 2007-04-11 2008-04-02 α−アミノアセタール類の脱アセタール化法
US12/595,469 US8609882B2 (en) 2007-04-11 2008-04-02 Process for deacetalisation of α aminoacetals
DK08718382.8T DK2137139T3 (en) 2007-04-11 2008-04-02 A process for deacetalization of the alpha-aminoacetaler
EP08718382.8A EP2137139B1 (fr) 2007-04-11 2008-04-02 Procédé de désacétalisation d'alpha-aminoacétals
ES08718382.8T ES2525372T3 (es) 2007-04-11 2008-04-02 Procedimiento de desacetilación de alfa-aminoacetales

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0702633A FR2914920B1 (fr) 2007-04-11 2007-04-11 Procede de deacetalisation d'alpha-aminoacetals.

Publications (2)

Publication Number Publication Date
FR2914920A1 FR2914920A1 (fr) 2008-10-17
FR2914920B1 true FR2914920B1 (fr) 2011-09-09

Family

ID=38669006

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0702633A Expired - Fee Related FR2914920B1 (fr) 2007-04-11 2007-04-11 Procede de deacetalisation d'alpha-aminoacetals.

Country Status (10)

Country Link
US (1) US8609882B2 (fr)
EP (1) EP2137139B1 (fr)
JP (1) JP5554698B2 (fr)
CN (1) CN101679223B (fr)
CA (1) CA2683612C (fr)
DK (1) DK2137139T3 (fr)
ES (1) ES2525372T3 (fr)
FR (1) FR2914920B1 (fr)
RU (1) RU2477270C2 (fr)
WO (1) WO2008125486A1 (fr)

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4002742A (en) * 1974-03-19 1977-01-11 Schering Corporation 1-N-alkyl-4,6-di-(aminoglycosyl)-1,3-diaminocyclitols, methods for their manufacture, methods for their use as antibacterial agents, and compositions useful therefor
JPS5695142A (en) * 1979-12-28 1981-08-01 T Hasegawa Co Ltd Preparation of aliphatic aldehyde
US5214129A (en) * 1985-01-23 1993-05-25 Abbott Laboratories Peptidylaminodiols
EP0249349B1 (fr) 1986-06-05 1992-10-14 Ici Americas Inc. Composés difluorocétoniques
GB8809316D0 (en) 1987-05-11 1988-05-25 Ici America Inc Heterocyclic ketones
US5329025A (en) * 1988-09-21 1994-07-12 G. D. Searle & Co. 3-azido compound
EP0371179A1 (fr) * 1988-10-28 1990-06-06 Merrell Dow Pharmaceuticals Inc. Analogues des substrats de peptidases
IL91997A0 (en) 1988-11-03 1990-07-12 American Cyanamid Co Aryloxy benzotriazole herbicidal agents and methods for the preparation thereof
DE3843390A1 (de) 1988-12-23 1990-07-05 Basf Ag Verfahren zur herstellung von optisch aktiven (alpha)-aminoacetalen
US5399763A (en) * 1993-02-01 1995-03-21 Nippon Kayaku Kabushiki Kaisha Process for preparing optically active 2-aminopropanal
US5837702A (en) * 1993-10-07 1998-11-17 Bristol-Myers Squibb Co. 4-arylamino-benzopyran and related compounds
JP3772351B2 (ja) * 1994-06-30 2006-05-10 大日本インキ化学工業株式会社 ビシクロヘキサン−４−オン誘導体
US5614649A (en) 1994-11-14 1997-03-25 Cephalon, Inc. Multicatalytic protease inhibitors
US5914332A (en) * 1995-12-13 1999-06-22 Abbott Laboratories Retroviral protease inhibiting compounds
GB9623908D0 (en) 1996-11-18 1997-01-08 Hoffmann La Roche Amino acid derivatives
US6184376B1 (en) * 1997-02-10 2001-02-06 Mediver Ab Synthesis of acyclic nucleoside derivatives
AT410791B (de) * 2000-05-31 2003-07-25 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von acyloxyacetaldehyden
FR2843112B1 (fr) 2002-07-30 2004-10-22 Clariant Procede de preparation d'amines primaires.
CN1946691A (zh) 2004-02-27 2007-04-11 先灵公司 作为丙型肝炎病毒ns3丝氨酸蛋白酶抑制剂的化合物
AR055395A1 (es) * 2005-08-26 2007-08-22 Vertex Pharma Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c

Also Published As

Publication number Publication date
CA2683612C (fr) 2015-06-23
ES2525372T3 (es) 2014-12-23
US8609882B2 (en) 2013-12-17
JP2010523615A (ja) 2010-07-15
WO2008125486A1 (fr) 2008-10-23
RU2477270C2 (ru) 2013-03-10
CN101679223A (zh) 2010-03-24
FR2914920A1 (fr) 2008-10-17
US20100137633A1 (en) 2010-06-03
CA2683612A1 (fr) 2008-10-23
RU2009141621A (ru) 2011-05-20
EP2137139B1 (fr) 2014-09-10
JP5554698B2 (ja) 2014-07-23
CN101679223B (zh) 2014-04-16
DK2137139T3 (en) 2014-12-15
EP2137139A1 (fr) 2009-12-30

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Legal Events

Date Code Title Description
CA Change of address

Effective date: 20130830

PLFP Fee payment

Year of fee payment: 9

ST Notification of lapse

Effective date: 20161230