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FR2731618B1 - Composition ophtalmique topique comprenant un derive de 2-(4-(azolylbutyl)-piperazinyl-methyl)-benzimidazole, notamment pour le traitement de la conjonctivite allergique - Google Patents

Composition ophtalmique topique comprenant un derive de 2-(4-(azolylbutyl)-piperazinyl-methyl)-benzimidazole, notamment pour le traitement de la conjonctivite allergique

Info

Publication number
FR2731618B1
FR2731618B1 FR9502910A FR9502910A FR2731618B1 FR 2731618 B1 FR2731618 B1 FR 2731618B1 FR 9502910 A FR9502910 A FR 9502910A FR 9502910 A FR9502910 A FR 9502910A FR 2731618 B1 FR2731618 B1 FR 2731618B1
Authority
FR
France
Prior art keywords
conjunctivity
azolylbutyl
benzimidazole
piperazinyl
allergic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9502910A
Other languages
English (en)
Other versions
FR2731618A1 (fr
Inventor
Altisent Maria Rosa Cuberes
Constansa Jordi Frigola
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Esteve Pharmaceuticals SA
Original Assignee
Laboratorios del Dr Esteve SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios del Dr Esteve SA filed Critical Laboratorios del Dr Esteve SA
Priority to FR9502910A priority Critical patent/FR2731618B1/fr
Priority to US08/613,843 priority patent/US5641781A/en
Priority to PCT/EP1996/001148 priority patent/WO1996028161A1/fr
Priority to JP8527293A priority patent/JPH10500427A/ja
Priority to ES09600606A priority patent/ES2117558B1/es
Priority to EP96908059A priority patent/EP0760663A1/fr
Priority to CA002190187A priority patent/CA2190187A1/fr
Priority to AU51452/96A priority patent/AU718008B2/en
Priority to ZA962060A priority patent/ZA962060B/xx
Publication of FR2731618A1 publication Critical patent/FR2731618A1/fr
Priority to BR1100709-5A priority patent/BR1100709A/pt
Application granted granted Critical
Publication of FR2731618B1 publication Critical patent/FR2731618B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR9502910A 1995-03-14 1995-03-14 Composition ophtalmique topique comprenant un derive de 2-(4-(azolylbutyl)-piperazinyl-methyl)-benzimidazole, notamment pour le traitement de la conjonctivite allergique Expired - Fee Related FR2731618B1 (fr)

Priority Applications (10)

Application Number Priority Date Filing Date Title
FR9502910A FR2731618B1 (fr) 1995-03-14 1995-03-14 Composition ophtalmique topique comprenant un derive de 2-(4-(azolylbutyl)-piperazinyl-methyl)-benzimidazole, notamment pour le traitement de la conjonctivite allergique
US08/613,843 US5641781A (en) 1995-03-14 1996-03-11 Topical ophthalmic composition comprising a 2-[4-(azolylbutyl)piperazinylmethyl]benzimidazole derivative, in particular for the treatment of allergic conjunctivitis
JP8527293A JPH10500427A (ja) 1995-03-14 1996-03-13 アレルギー性結膜炎を治療するための２−（４−（アゾリルブチル）−ピペラジニル−メチル）−ベンズイミダゾール誘導体の使用
ES09600606A ES2117558B1 (es) 1995-03-14 1996-03-13 Composicion oftalmica topica que comprende un derivado de 2-(4-(azolilbutil)-piperazinil-metil)-benzimidazol, principalmente para el tratamiento de la conjuntivitis alergica.
EP96908059A EP0760663A1 (fr) 1995-03-14 1996-03-13 Utilisation des derives de 2- 4-(azolylbutyl)-piperazinyl-methyl]-benzimidazole pour le traitement de la conjonctivite allergique
CA002190187A CA2190187A1 (fr) 1995-03-14 1996-03-13 Utilisation des derives de 2-[4-(azolylbutyl)-piperazinyl-methyl]-benzimidazole pour le traitement de la conjonctivite allergique
PCT/EP1996/001148 WO1996028161A1 (fr) 1995-03-14 1996-03-13 Utilisation des derives de 2-[4-(azolylbutyl)-piperazinyl-methyl]-benzimidazole pour le traitement de la conjonctivite allergique
AU51452/96A AU718008B2 (en) 1995-03-14 1996-03-13 Use of a 2-(4-(azolylbutyl)-piperazinyl-methyl)- benzimidazole derivative for treating allergic conjunctivitis
ZA962060A ZA962060B (en) 1995-03-14 1996-03-14 Topical ophthalmic composition comprising a 2-(4-(azolylbutyl)-piperazinyl)benzimidazole derivative in particular for the treatment of allergic conjunctivitis
BR1100709-5A BR1100709A (pt) 1995-03-14 1997-05-08 Composição oftálmica tópica , e, utilização de um composto

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9502910A FR2731618B1 (fr) 1995-03-14 1995-03-14 Composition ophtalmique topique comprenant un derive de 2-(4-(azolylbutyl)-piperazinyl-methyl)-benzimidazole, notamment pour le traitement de la conjonctivite allergique

Publications (2)

Publication Number Publication Date
FR2731618A1 FR2731618A1 (fr) 1996-09-20
FR2731618B1 true FR2731618B1 (fr) 1997-08-01

Family

ID=9476989

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9502910A Expired - Fee Related FR2731618B1 (fr) 1995-03-14 1995-03-14 Composition ophtalmique topique comprenant un derive de 2-(4-(azolylbutyl)-piperazinyl-methyl)-benzimidazole, notamment pour le traitement de la conjonctivite allergique

Country Status (9)

Country Link
US (1) US5641781A (fr)
EP (1) EP0760663A1 (fr)
JP (1) JPH10500427A (fr)
AU (1) AU718008B2 (fr)
CA (1) CA2190187A1 (fr)
ES (1) ES2117558B1 (fr)
FR (1) FR2731618B1 (fr)
WO (1) WO1996028161A1 (fr)
ZA (1) ZA962060B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7355042B2 (en) * 2001-10-16 2008-04-08 Hypnion, Inc. Treatment of CNS disorders using CNS target modulators
EP1560540A4 (fr) * 2002-10-18 2008-03-19 Molichem Medicines Inc Methodes de traitement de la maladie de l'oeil sec avec des lantibiotiques
US7326683B2 (en) * 2004-05-06 2008-02-05 Molichem Medicines, Inc. Treatment of membrane-associated diseases and disorders using lantibiotic containing compositions
EP1753445A4 (fr) * 2004-05-06 2009-05-20 Molichem Medicines Inc Traitement de maladies et de troubles oculaires utilisant des compositions lantibiotiques

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2665161B1 (fr) * 1990-07-26 1992-11-27 Esteve Labor Dr Nouveaux derives de benzimidazole, leur preparation et leur application en tant que medicaments.
FR2674856B1 (fr) * 1991-04-05 1993-07-30 Esteve Labor Dr Nouveaux antihistaminiques non sedatifs, derives de benzimidazole, leur procede de preparation et leur utilisation en tant que medicaments.
JP3527256B2 (ja) * 1992-12-09 2004-05-17 ロート製薬株式会社 抗アレルギー点眼剤

Also Published As

Publication number Publication date
CA2190187A1 (fr) 1996-09-19
ZA962060B (en) 1996-12-31
WO1996028161A1 (fr) 1996-09-19
JPH10500427A (ja) 1998-01-13
ES2117558B1 (es) 1999-09-16
AU718008B2 (en) 2000-04-06
FR2731618A1 (fr) 1996-09-20
US5641781A (en) 1997-06-24
EP0760663A1 (fr) 1997-03-12
AU5145296A (en) 1996-10-02
ES2117558A1 (es) 1998-08-01

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Legal Events

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