[go: up one dir, main page]

FR2624741B1 - Compositions a base d'une combinaison de liposomes et de lymphokine presentant des proprietes immunostimulantes et leurs applications en medecine humaine et veterinaire - Google Patents

Compositions a base d'une combinaison de liposomes et de lymphokine presentant des proprietes immunostimulantes et leurs applications en medecine humaine et veterinaire

Info

Publication number
FR2624741B1
FR2624741B1 FR8717799A FR8717799A FR2624741B1 FR 2624741 B1 FR2624741 B1 FR 2624741B1 FR 8717799 A FR8717799 A FR 8717799A FR 8717799 A FR8717799 A FR 8717799A FR 2624741 B1 FR2624741 B1 FR 2624741B1
Authority
FR
France
Prior art keywords
lymphokine
liposomes
human
applications
combination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR8717799A
Other languages
English (en)
Other versions
FR2624741A1 (fr
Inventor
Pierre Perrin
Marie-Line Joffret
Claude Leclerc
Pierre Sureau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Pasteur
Original Assignee
Institut Pasteur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Pasteur filed Critical Institut Pasteur
Priority to FR8717799A priority Critical patent/FR2624741B1/fr
Priority to PT89271A priority patent/PT89271A/pt
Priority to PCT/FR1988/000630 priority patent/WO1989005631A1/fr
Priority to EP89900836A priority patent/EP0391962A1/fr
Priority to JP1500768A priority patent/JPH05504756A/ja
Publication of FR2624741A1 publication Critical patent/FR2624741A1/fr
Application granted granted Critical
Publication of FR2624741B1 publication Critical patent/FR2624741B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2013—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
  • Polyamides (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
FR8717799A 1987-12-21 1987-12-21 Compositions a base d'une combinaison de liposomes et de lymphokine presentant des proprietes immunostimulantes et leurs applications en medecine humaine et veterinaire Expired - Lifetime FR2624741B1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR8717799A FR2624741B1 (fr) 1987-12-21 1987-12-21 Compositions a base d'une combinaison de liposomes et de lymphokine presentant des proprietes immunostimulantes et leurs applications en medecine humaine et veterinaire
PT89271A PT89271A (pt) 1987-12-21 1988-12-20 Processo para a preparacao de composicoes farmaceuticas contendo interleucina-2 com propriedades imunoestimulantes e suas aplicacoes em medicina humana e veterinaria
PCT/FR1988/000630 WO1989005631A1 (fr) 1987-12-21 1988-12-21 Compositions presentant des proprietes immunostimulantes et leurs applications en medecine humaine et veterinaire
EP89900836A EP0391962A1 (fr) 1987-12-21 1988-12-21 Compositions presentant des proprietes immunostimulantes et leurs applications en medecine humaine et veterinaire
JP1500768A JPH05504756A (ja) 1987-12-21 1988-12-21 免疫刺激性を有する組成物と、そのヒトと獣医学用医薬への応用

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8717799A FR2624741B1 (fr) 1987-12-21 1987-12-21 Compositions a base d'une combinaison de liposomes et de lymphokine presentant des proprietes immunostimulantes et leurs applications en medecine humaine et veterinaire

Publications (2)

Publication Number Publication Date
FR2624741A1 FR2624741A1 (fr) 1989-06-23
FR2624741B1 true FR2624741B1 (fr) 1991-06-28

Family

ID=9358089

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8717799A Expired - Lifetime FR2624741B1 (fr) 1987-12-21 1987-12-21 Compositions a base d'une combinaison de liposomes et de lymphokine presentant des proprietes immunostimulantes et leurs applications en medecine humaine et veterinaire

Country Status (5)

Country Link
EP (1) EP0391962A1 (fr)
JP (1) JPH05504756A (fr)
FR (1) FR2624741B1 (fr)
PT (1) PT89271A (fr)
WO (1) WO1989005631A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2955314B2 (ja) * 1988-10-27 1999-10-04 リージェンツ・オブ・ザ・ユニバーシティー・オブ・ミネソタ Ｉｌ―２含有リポソーム免疫アジュバント
NL9000207A (fr) * 1990-01-29 1991-08-16 Duphar Int Res
EP0548210A1 (fr) * 1990-09-10 1993-06-30 School Of Pharmacy, University Of London Liposomes
WO1993012813A1 (fr) * 1991-12-31 1993-07-08 Zymogenetics, Inc. Procedes et compositions pour reduire la perte de sang
DK0702563T3 (da) * 1993-05-27 2003-11-10 Entremed Inc Sammensætninger og fremgangsmåder til behandling af cancer og hyperproliferative sygdomme
US5871914A (en) * 1993-06-03 1999-02-16 Intelligene Ltd. Method for detecting a nucleic acid involving the production of a triggering RNA and transcription amplification
US6057099A (en) * 1994-12-02 2000-05-02 Intelligene Ltd. Detection of nucleic acid sequences
US6087174A (en) * 1996-12-26 2000-07-11 Johns Hopkins University, School Of Medicine Growth medium for primary pancreatic tumor cell culture
FR2808193B1 (fr) * 2000-04-26 2004-05-07 Biovector Therapeutics Utilisation de l'il-2 et de vecteurs synthetiques dans le traitement des cancers
JP2004508290A (ja) * 2000-04-26 2004-03-18 バイオベクター　セラピューティクス 免疫調節における粒状ベクターの使用
CU23923B1 (es) * 2010-11-12 2013-07-31 Ct De Inmunología Molecular Polipéptidos derivados de la il-2 con actividad agonista
RU2522866C1 (ru) * 2013-03-06 2014-07-20 Федеральное государственное унитарное предприятие "Щелковский биокомбинат" Способ получения антирабической вакцины

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0047480B1 (fr) * 1980-09-05 1986-02-05 Institut Armand Frappier Formation d'un immunosome préparé exclusivement d'antigènes viraux reconstitués sur une membrane artificielle
CH668554A5 (de) * 1984-04-09 1989-01-13 Sandoz Ag Liposomen welche polypeptide mit interleukin-2-aktivitaet enthalten sowie verfahren zu ihrer herstellung.
JPS63502117A (ja) * 1986-02-10 1988-08-18 リポソ−ム　テクノロジ−，インコ−ポレイテッド 放出を制御されたリポソ−ム供給系

Also Published As

Publication number Publication date
PT89271A (pt) 1989-12-29
EP0391962A1 (fr) 1990-10-17
WO1989005631A1 (fr) 1989-06-29
FR2624741A1 (fr) 1989-06-23
JPH05504756A (ja) 1993-07-22

Similar Documents

Publication Publication Date Title
ZA899176B (en) Use of acetyl d-carnitine in the therapeutic treatment of glaucoma and pharmaceutical compositions useful in such treatment
FR2624741B1 (fr) Compositions a base d'une combinaison de liposomes et de lymphokine presentant des proprietes immunostimulantes et leurs applications en medecine humaine et veterinaire
ATE63813T1 (de) Pharmazeutische zusammensetzungen von dihydrocodeine/ibuprofen und verfahren.
IT9021091A0 (it) Procedimento per la preparazione di composizioni farmaceutiche aventi aumentata velocita' di dissoluzione della sostanza attiva e composi- zioni ottenute
NO920109L (no) Biologisk nedbrytbar toeymykningsblanding eller -gjenstandog fremstilling derav
IT1230485B (it) Particelle fini di poliorganosilsesquiossano e procedimento per produrre le stesse
FR2633182B1 (fr) Composition pharmaceutique anticancereuse et methode d'utilisation de l'invention
IL81233A (en) Functionalized peptidyl aminodiols and-triols and pharmaceutical compositions comprising them
FR2776657B1 (fr) Composes bicycliques-aromatiques et leur utilisation en medecine humaine ou veterinaire ainsi qu'en cosmetologie
EP0933994A4 (fr) Applications therapeutiques et diagnostiques d'alleles produits par epissure dans le domaine i du perlecan
FR2462167B1 (fr) Interferon de fibroplastes humains sous la forme d'une proteine homogene et sa preparation
FR2753376B1 (fr) Compositions pharmaceutiques comprenant de l'amisulpride et leurs applications therapeutiques
DK192988A (da) Dihydropyridinamider, deres fremstilling og anvendelse
BR8807257A (pt) Composicoes monomericas e polimericas de ciclobutareno-cetoanilina
FR2779720B1 (fr) Nouveaux composes diarylselenures et leur utilisation en medecine humaine ou veterinaire ainsi qu'en cosmetologie
FI913552A7 (fi) Haaroituneen lohko-kopolymeerin valmistus ja käyttö
FR2598312B1 (fr) Aerateur sinusien permanent trans-nasal en double " t "
IT1217797B (it) Composizioni erbicide a base di clomazone e metodi di impiego implicanto una maggiore tolleranza nel caso di colture di mais ed altre colture
FR2652001B1 (fr) Composition dermato-cosmetique a base d'acide rosmarinique presentant des proprietes de filtre solaire et d'agent anti-inflammatoire.
CA2150234A1 (fr) Association d'atovaquone et de proguanil pour le traitement d'infection à protozoaires
EP0365956A3 (fr) Agents carcinostatiques
DE69031493D1 (de) Uv-absorbierende verbindungen und zusammensetzungen
FR2607006B1 (fr) Composition pharmaceutique a base d'euphorbia pilulifera et/ou hirta, utilisee notamment comme cicatrisant et/ou desinfectant intestinal
ES8703872A1 (es) Procedimiento para preparar derivados de isoquinolina.
ITMI931082A0 (it) Coniugati di farmaci antivirali ad attivita' epatotropicaq relativi veicolanti e composizioni farmaceutiche che li contengono

Legal Events

Date Code Title Description
ST Notification of lapse