FR2598706B1 - Derives de tetrahydronaphtalene, compositions pharmaceutiques les contenant et procede de preparation - Google Patents
Derives de tetrahydronaphtalene, compositions pharmaceutiques les contenant et procede de preparationInfo
- Publication number
- FR2598706B1 FR2598706B1 FR878706564A FR8706564A FR2598706B1 FR 2598706 B1 FR2598706 B1 FR 2598706B1 FR 878706564 A FR878706564 A FR 878706564A FR 8706564 A FR8706564 A FR 8706564A FR 2598706 B1 FR2598706 B1 FR 2598706B1
- Authority
- FR
- France
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- tetrahydronaphtalene
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/23—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1938/86A CH668962A5 (de) | 1986-05-13 | 1986-05-13 | Tetrahydronaphthyl-propenyl-phenole. |
| CH74287 | 1987-02-26 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2598706A1 FR2598706A1 (fr) | 1987-11-20 |
| FR2598706B1 true FR2598706B1 (fr) | 1990-07-06 |
Family
ID=25685550
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR878706564A Expired - Lifetime FR2598706B1 (fr) | 1986-05-13 | 1987-05-11 | Derives de tetrahydronaphtalene, compositions pharmaceutiques les contenant et procede de preparation |
Country Status (20)
| Country | Link |
|---|---|
| CN (1) | CN87103524A (fr) |
| AU (1) | AU7277987A (fr) |
| BE (1) | BE1001668A5 (fr) |
| DE (1) | DE3715809A1 (fr) |
| DK (1) | DK232087A (fr) |
| ES (1) | ES2005572A6 (fr) |
| FI (1) | FI872027A7 (fr) |
| FR (1) | FR2598706B1 (fr) |
| GB (1) | GB2190378B (fr) |
| HU (1) | HU198002B (fr) |
| IL (1) | IL82448A0 (fr) |
| IT (1) | IT1203954B (fr) |
| LU (1) | LU86866A1 (fr) |
| MC (1) | MC1817A1 (fr) |
| NL (1) | NL8701101A (fr) |
| NO (1) | NO871961L (fr) |
| NZ (1) | NZ220215A (fr) |
| PT (1) | PT84860B (fr) |
| SE (1) | SE8701933L (fr) |
| ZW (1) | ZW6587A1 (fr) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5602130A (en) * | 1987-03-20 | 1997-02-11 | Allergan | Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity |
| US5264578A (en) | 1987-03-20 | 1993-11-23 | Allergan, Inc. | Disubstituted acetylenes bearing heterobicyclic groups and heteroaromatic or phenyl groups having retinoid like activity |
| CA2017956A1 (fr) * | 1989-07-06 | 1991-01-06 | Werner Bollag | Utilisation de retinoides |
| US5272156A (en) * | 1989-09-19 | 1993-12-21 | Allergan, Inc. | Acetylenes disubstituted with a heteroaromatic group and a 2-substituted 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity |
| US5183827A (en) * | 1989-09-19 | 1993-02-02 | Allergan, Inc. | Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity |
| US5264456A (en) * | 1989-12-29 | 1993-11-23 | Allergan, Inc. | Acetylenes disubstituted with a furyl group and a substituted phenyl group having retinoid like activity |
| US5324840A (en) | 1992-06-11 | 1994-06-28 | Allergan, Inc. | Method of treatment with compounds having retinoid-like activity and reduced skin toxicity and lacking teratogenic effects |
| US6172115B1 (en) | 1993-02-11 | 2001-01-09 | Allergan Sales, Inc. | Method for preventing onset of restenosis after angioplasty employing an RXR-specific retinoid |
| US5455265A (en) * | 1993-02-11 | 1995-10-03 | Allergan, Inc. | Method of treatment with compounds having selective agonist-like activity on RXR retinoid receptors |
| US5475022A (en) * | 1993-10-18 | 1995-12-12 | Allergan, Inc. | Phenyl or heteroaryl and tetrahydronaphthyl substituted diene compounds having retinoid like biological activity |
| US5426118A (en) * | 1993-12-30 | 1995-06-20 | Allergan, Inc. | [4-(1,2-epoxycyclohexanyl)but-3-en-1-ynyl]aromatic and heteroaromatic acids and derivatives having retinoid-like biological activity |
| US5498755A (en) * | 1994-08-23 | 1996-03-12 | Chandraratna; Roshantha A. | Disubstituted aryl and heteroaryl imines having retinoid-like biological activity |
| US5618931A (en) * | 1994-12-29 | 1997-04-08 | Allergan | Acetylenes disubstituted with a 5 substituted dihydronaphthyl group and with an aryl or heteroaryl group having retinoid-like biological activity |
| US5543534A (en) * | 1994-12-29 | 1996-08-06 | Allergan | Acetylenes disubstituted with a 5 substituted tetrahydronaphthyl group and with an aryl or heteroaryl groups having retinoid-like biological activity |
| US5556996A (en) * | 1994-12-29 | 1996-09-17 | Allergan | Oxiranyls disubstituted with a phenyl group and a substituted chromanyl or tetrahydroquinolinyl group having retinoid like activity |
| US5618943A (en) * | 1994-12-29 | 1997-04-08 | Allergan | Acetylenes disubstituted with a 5 OXO substituted tetrahydronaphthyl group and with an aryl or heteroaryl group having retinoid-like biological activity |
| US5599967A (en) * | 1994-12-29 | 1997-02-04 | Allergan | Acetylenes disubstituted with a 5 substituted tetrahydronaphthyl group and with an aryl of heteroaryl group having retinoid-like biological activity |
| US5648514A (en) | 1994-12-29 | 1997-07-15 | Allergan | Substituted acetylenes having retinoid-like biological activity |
| US5534641A (en) * | 1994-12-29 | 1996-07-09 | Allergan | Acetylenes disubstituted with 2-tetrahydropyranoxyaryl and aryl or heteroaryl groups having retinoid-like biological activity |
| US5489584A (en) * | 1994-12-29 | 1996-02-06 | Allergan, Inc. | Acetylenes disubstituted with a 5-amino or substituted 5-amino substituted tetrahydronaphthyl group and with an aryl or heteroaryl group having retinoid-like biological activity |
| US5514825A (en) * | 1994-12-29 | 1996-05-07 | Allergan, Inc. | Acetylenes disubstituted with a 5 substituted tetrahydronaphthyl group and with an aryl or heteroaryl group having retinoid-like biological activity |
| US5534261A (en) * | 1995-01-17 | 1996-07-09 | University Of Southern California | Retinoid-based compositions and method for preventing adhesion formation using the same |
| US6025388A (en) * | 1995-04-26 | 2000-02-15 | Allergan Sales, Inc. | Method for inhibiting gene expression promoted by AP1 protein with RARβ selective retinoids and method for treatment of diseases and conditions with such retinoids |
| US5616712A (en) * | 1995-05-16 | 1997-04-01 | Allergan | Acetylenes disubstituted with a phenyl or heteroaryl group and a 2-thio-1,2,3,4-tetrahdroquinolinyl, 2-alkylthio-3,4-dihydroquinolinyl or 2-alkoxy-3,4-dihydroquinolinyl group having retinoid-like biological activity |
| US5917082A (en) | 1995-06-06 | 1999-06-29 | Allergan Sales, Inc. | 2,4-pentadienoic acid derivatives having retinoid-like biological activity |
| US5675033A (en) * | 1995-06-06 | 1997-10-07 | Allergan | 2,4-pentadienoic acid derivatives having retinoid-like biological activity |
| US6942980B1 (en) | 1995-09-01 | 2005-09-13 | Allergan, Inc. | Methods of identifying compounds having nuclear receptor negative hormone and/or antagonist activities |
| US6008204A (en) | 1995-09-01 | 1999-12-28 | Allergan Sales, Inc. | Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities |
| US5958954A (en) | 1995-09-01 | 1999-09-28 | Allergan Sales, Inc. | Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities |
| US6218128B1 (en) | 1997-09-12 | 2001-04-17 | Allergan Sales, Inc. | Methods of identifying compounds having nuclear receptor negative hormone and/or antagonist activities |
| US5952345A (en) | 1995-09-01 | 1999-09-14 | Allergan Sales, Inc. | Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities |
| AU7598596A (en) * | 1995-11-01 | 1997-05-22 | Allergan, Inc. | Sulfides, sulfoxides and sulfones disubstituted with a tetrahydronaphthalenyl, chromanyl, thiochromanyl or tetrahydroquinolinyl and substituted phenyl or heteroaryl group, having retinoid-like biological activity |
| US5675024A (en) | 1995-11-22 | 1997-10-07 | Allergan | Aryl or heteroaryl amides of tetrahydronaphthalene, chroman, thiochroman and 1,2,3,4,-tetrahydroquinoline carboxylic acids, having an electron withdrawing substituent in the aromatic or heteroaromatic moiety, having retinoid-like biological activity |
| US5663357A (en) | 1995-11-22 | 1997-09-02 | Allergan | Substituted heteroarylamides having retinoid-like biological activity |
| US5688957A (en) * | 1995-12-29 | 1997-11-18 | Allergan | (3"-thioxacyclohex-1"-enyl)!-but-3'-ene-1'-ynyl!aryl and (3"-thioxacyclohex-1"-enyl)!-but-3'-ene-1'-ynyl!heteroaryl carboxylic acids and esters having retinoid-like biological activity |
| US5965606A (en) | 1995-12-29 | 1999-10-12 | Allergan Sales, Inc. | Methods of treatment with compounds having RAR.sub.α receptor specific or selective activity |
| US5763635A (en) * | 1996-06-21 | 1998-06-09 | Allergan | Tetrahydronaphthalene derivatives substituted in the 8 position with alkyhidene groups having retinoid and/or retinoid antagonist-like biological activity |
| US6555690B2 (en) | 1996-06-21 | 2003-04-29 | Allergan, Inc. | Alkyl or aryl substituted dihydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity |
| US5808124A (en) * | 1996-06-21 | 1998-09-15 | Allergan | O- or S-substituted dihydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity |
| US5773594A (en) | 1996-06-21 | 1998-06-30 | Allergan | Alkyl or aryl substituted dihydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity |
| US5723666A (en) * | 1996-06-21 | 1998-03-03 | Allergan | Oxime substituted tetrahydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity |
| US5747542A (en) * | 1996-06-21 | 1998-05-05 | Allergan | Oxo-substituted tetrahydronaphthalene derivatives having retinold and/or retinoid antagonist-like biological activity |
| US5741896A (en) | 1996-06-21 | 1998-04-21 | Allergan | O- or S- substituted tetrahydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity |
| US5739338A (en) * | 1996-11-05 | 1998-04-14 | Allergan | N-aryl substituted tetrahydroquinolines having retinoid agonist, retinoid antagonist or retinoid inverse agonist type biological activity |
| US5728846A (en) | 1996-12-12 | 1998-03-17 | Allergan | Benzo 1,2-g!-chrom-3-ene and benzo 1,2-g!-thiochrom-3-ene derivatives |
| US5760276A (en) | 1997-03-06 | 1998-06-02 | Allergan | Aryl-and heteroarylcyclohexenyl substituted alkenes having retinoid agonist, antagonist or inverse agonist type biological activity |
| US6037488A (en) | 1997-04-19 | 2000-03-14 | Allergan Sales, Inc. | Trisubstituted phenyl derivatives having retinoid agonist, antagonist or inverse agonist type biological activity |
| US5919970A (en) | 1997-04-24 | 1999-07-06 | Allergan Sales, Inc. | Substituted diaryl or diheteroaryl methanes, ethers and amines having retinoid agonist, antagonist or inverse agonist type biological activity |
| US6313107B1 (en) | 2000-08-29 | 2001-11-06 | Allergan Sales, Inc. | Methods of providing and using compounds having activity as inhibitors of cytochrome P450RAI |
| US6369225B1 (en) | 2000-08-29 | 2002-04-09 | Allergan Sales, Inc. | Compounds having activity as inhibitors of cytochrome P450RAI |
| US6380256B1 (en) | 2000-08-29 | 2002-04-30 | Allergan Sales, Inc. | Compounds having activity as inhibitors of cytochrome P450RAI |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4326055A (en) * | 1977-12-22 | 1982-04-20 | Hoffmann-La Roche Inc. | Stilbene derivatives |
| CA1162200A (fr) * | 1981-02-13 | 1984-02-14 | Michael Klaus | Procede de fabrication de derives indanyl (ou tetrahydronaphtyl)propenyl-phenyliques |
| DE3202100A1 (de) * | 1982-01-23 | 1983-08-04 | Basf Ag, 6700 Ludwigshafen | Substituierte benzoesaeure-4-hydroxyanilide, ihre herstellung und diese enthaltende pharmazeutische zubereitungen |
| EP0084667B1 (fr) * | 1982-01-23 | 1985-09-18 | BASF Aktiengesellschaft | Dérivés de phényléthylène, leur préparation et utilisation à titre de médicaments |
| DE3602473A1 (de) * | 1986-01-28 | 1987-07-30 | Basf Ag | Vinylphenolderivate, ihre herstellung und verwendung |
-
1987
- 1987-04-10 ZW ZW65/87A patent/ZW6587A1/xx unknown
- 1987-04-23 IT IT20232/87A patent/IT1203954B/it active
- 1987-05-06 LU LU86866A patent/LU86866A1/de unknown
- 1987-05-06 DK DK232087A patent/DK232087A/da not_active Application Discontinuation
- 1987-05-06 NZ NZ220215A patent/NZ220215A/xx unknown
- 1987-05-07 IL IL82448A patent/IL82448A0/xx unknown
- 1987-05-07 FI FI872027A patent/FI872027A7/fi not_active Application Discontinuation
- 1987-05-08 NL NL8701101A patent/NL8701101A/nl not_active Application Discontinuation
- 1987-05-11 FR FR878706564A patent/FR2598706B1/fr not_active Expired - Lifetime
- 1987-05-11 MC MC871883A patent/MC1817A1/fr unknown
- 1987-05-11 SE SE8701933A patent/SE8701933L/ not_active Application Discontinuation
- 1987-05-11 BE BE8700505A patent/BE1001668A5/fr not_active IP Right Cessation
- 1987-05-11 HU HU872103A patent/HU198002B/hu not_active IP Right Cessation
- 1987-05-12 NO NO871961A patent/NO871961L/no unknown
- 1987-05-12 AU AU72779/87A patent/AU7277987A/en not_active Abandoned
- 1987-05-12 GB GB8711205A patent/GB2190378B/en not_active Expired - Lifetime
- 1987-05-12 PT PT84860A patent/PT84860B/pt not_active IP Right Cessation
- 1987-05-12 ES ES8701419A patent/ES2005572A6/es not_active Expired
- 1987-05-12 CN CN198787103524A patent/CN87103524A/zh active Pending
- 1987-05-12 DE DE19873715809 patent/DE3715809A1/de not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| ZW6587A1 (en) | 1987-12-02 |
| NO871961L (no) | 1987-11-16 |
| FI872027L (fi) | 1987-11-14 |
| ES2005572A6 (es) | 1989-03-16 |
| NZ220215A (en) | 1990-06-26 |
| IL82448A0 (en) | 1987-11-30 |
| PT84860A (en) | 1987-06-01 |
| MC1817A1 (fr) | 1988-03-18 |
| DK232087D0 (da) | 1987-05-06 |
| LU86866A1 (de) | 1988-06-13 |
| SE8701933L (sv) | 1987-11-14 |
| GB2190378A (en) | 1987-11-18 |
| NO871961D0 (no) | 1987-05-12 |
| GB8711205D0 (en) | 1987-06-17 |
| FI872027A0 (fi) | 1987-05-07 |
| IT1203954B (it) | 1989-02-23 |
| AU7277987A (en) | 1987-11-19 |
| HU198002B (en) | 1989-07-28 |
| SE8701933D0 (sv) | 1987-05-11 |
| GB2190378B (en) | 1990-11-14 |
| FI872027A7 (fi) | 1987-11-14 |
| IT8720232A0 (it) | 1987-04-23 |
| DK232087A (da) | 1987-11-14 |
| HUT43806A (en) | 1987-12-28 |
| CN87103524A (zh) | 1987-12-02 |
| PT84860B (pt) | 1990-02-08 |
| BE1001668A5 (fr) | 1990-02-06 |
| NL8701101A (nl) | 1987-12-01 |
| DE3715809A1 (de) | 1987-11-19 |
| FR2598706A1 (fr) | 1987-11-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TP | Transmission of property | ||
| ST | Notification of lapse |