FR2364029A1 - Medicament a base d'un derive de l'acide phenylacetique - Google Patents
Medicament a base d'un derive de l'acide phenylacetiqueInfo
- Publication number
- FR2364029A1 FR2364029A1 FR7726891A FR7726891A FR2364029A1 FR 2364029 A1 FR2364029 A1 FR 2364029A1 FR 7726891 A FR7726891 A FR 7726891A FR 7726891 A FR7726891 A FR 7726891A FR 2364029 A1 FR2364029 A1 FR 2364029A1
- Authority
- FR
- France
- Prior art keywords
- hydroxy
- alkyl
- phenylacetic acid
- cycloalkyl
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 230000002456 anti-arthritic effect Effects 0.000 title abstract 2
- 230000003110 anti-inflammatory effect Effects 0.000 title abstract 2
- 230000001754 anti-pyretic effect Effects 0.000 title abstract 2
- 239000002221 antipyretic Substances 0.000 title abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 title abstract 2
- 239000000106 platelet aggregation inhibitor Substances 0.000 title abstract 2
- SXQMCNKPZIBQGQ-UHFFFAOYSA-N 2-(2-hydroxyphenyl)-2-phenylacetic acid Chemical compound C=1C=CC=C(O)C=1C(C(=O)O)C1=CC=CC=C1 SXQMCNKPZIBQGQ-UHFFFAOYSA-N 0.000 title 1
- 101000783577 Dendroaspis angusticeps Thrombostatin Proteins 0.000 title 1
- 101000783578 Dendroaspis jamesoni kaimosae Dendroaspin Proteins 0.000 title 1
- 230000000202 analgesic effect Effects 0.000 title 1
- 229940127218 antiplatelet drug Drugs 0.000 title 1
- 210000001772 blood platelet Anatomy 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- CCVYRRGZDBSHFU-UHFFFAOYSA-N (2-hydroxyphenyl)acetic acid Chemical compound OC(=O)CC1=CC=CC=C1O CCVYRRGZDBSHFU-UHFFFAOYSA-N 0.000 abstract 2
- 206010003246 arthritis Diseases 0.000 abstract 2
- MHPYDQXOJSSKDU-UHFFFAOYSA-N 2-(5-chloro-4-cyclohexyl-2-hydroxyphenyl)acetic acid Chemical compound C1=C(O)C(CC(=O)O)=CC(Cl)=C1C1CCCCC1 MHPYDQXOJSSKDU-UHFFFAOYSA-N 0.000 abstract 1
- -1 3-8C Chemical group 0.000 abstract 1
- 206010030113 Oedema Diseases 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 229940035676 analgesics Drugs 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 229940124346 antiarthritic agent Drugs 0.000 abstract 1
- 229940125716 antipyretic agent Drugs 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/54—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings and other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/52—Unsaturated compounds containing hydroxy or O-metal groups a hydroxy or O-metal group being bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/56—Unsaturated compounds containing hydroxy or O-metal groups containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/74—Unsaturated compounds containing —CHO groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
L'invention a pour objet un médicament exerçant notamment une action antiphlogistique. Le médicament de l'invention contient, à titre de principe actif, un dérivé de l'acide phénylacétique répondant à la formule :
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1138676 | 1976-09-08 | ||
| CH1152976 | 1976-09-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2364029A1 true FR2364029A1 (fr) | 1978-04-07 |
Family
ID=25708231
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7726891A Withdrawn FR2364029A1 (fr) | 1976-09-08 | 1977-09-05 | Medicament a base d'un derive de l'acide phenylacetique |
Country Status (2)
| Country | Link |
|---|---|
| FR (1) | FR2364029A1 (fr) |
| NL (1) | NL7709681A (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2427416A4 (fr) * | 2009-05-04 | 2012-10-03 | Prometic Biosciences Inc | Composés aromatiques substitués et utilisations pharmaceutiques de ceux-ci |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB971700A (en) * | 1961-02-02 | 1964-09-30 | Boots Pure Drug Co Ltd | Anti-Inflammatory Agents |
| BE665340A (fr) * | 1964-06-15 | 1965-12-13 | Merck & Co Inc | |
| FR2259599A1 (fr) * | 1974-02-05 | 1975-08-29 | Sandoz Sa | |
| US4013690A (en) * | 1974-02-05 | 1977-03-22 | Sandoz Ltd. | Organic compounds |
| CH589595A5 (en) * | 1974-04-11 | 1977-07-15 | Sandoz Ag | Antioedema and antiinflammatory phenyl-acetic acid derivs. - by reacting (2') methoxy-(4')-phenyl-phenylacetic acids with e.g. boron trihalide |
-
1977
- 1977-09-02 NL NL7709681A patent/NL7709681A/xx not_active Application Discontinuation
- 1977-09-05 FR FR7726891A patent/FR2364029A1/fr not_active Withdrawn
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB971700A (en) * | 1961-02-02 | 1964-09-30 | Boots Pure Drug Co Ltd | Anti-Inflammatory Agents |
| BE665340A (fr) * | 1964-06-15 | 1965-12-13 | Merck & Co Inc | |
| FR2259599A1 (fr) * | 1974-02-05 | 1975-08-29 | Sandoz Sa | |
| US4013690A (en) * | 1974-02-05 | 1977-03-22 | Sandoz Ltd. | Organic compounds |
| CH589595A5 (en) * | 1974-04-11 | 1977-07-15 | Sandoz Ag | Antioedema and antiinflammatory phenyl-acetic acid derivs. - by reacting (2') methoxy-(4')-phenyl-phenylacetic acids with e.g. boron trihalide |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2427416A4 (fr) * | 2009-05-04 | 2012-10-03 | Prometic Biosciences Inc | Composés aromatiques substitués et utilisations pharmaceutiques de ceux-ci |
| AU2010244930B2 (en) * | 2009-05-04 | 2016-07-28 | Liminal Biosciences Limited | Substituted aromatic compounds and pharmaceutical uses thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| NL7709681A (nl) | 1978-03-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |