FR2125175A2 - 3-1 substd-amino-carbonyl)-5-phenyl-oxa-zoli - Google Patents
3-1 substd-amino-carbonyl)-5-phenyl-oxa-zoliInfo
- Publication number
- FR2125175A2 FR2125175A2 FR7105295A FR7105295A FR2125175A2 FR 2125175 A2 FR2125175 A2 FR 2125175A2 FR 7105295 A FR7105295 A FR 7105295A FR 7105295 A FR7105295 A FR 7105295A FR 2125175 A2 FR2125175 A2 FR 2125175A2
- Authority
- FR
- France
- Prior art keywords
- phenyl
- zoli
- substd
- oxa
- carbonyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- WYNCHZVNFNFDNH-UHFFFAOYSA-N Oxazolidine Chemical compound C1COCN1 WYNCHZVNFNFDNH-UHFFFAOYSA-N 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000001773 anti-convulsant effect Effects 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- 229960003965 antiepileptics Drugs 0.000 abstract 1
- 239000002249 anxiolytic agent Substances 0.000 abstract 1
- 230000000949 anxiolytic effect Effects 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 239000012948 isocyanate Substances 0.000 abstract 1
- 150000002513 isocyanates Chemical class 0.000 abstract 1
- 239000003158 myorelaxant agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- C07D263/26—Oxygen atoms attached in position 2 with hetero atoms or acyl radicals directly attached to the ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
3-(Subst. aminocarbonyl)-5-phenyl-oxazolidin-2-one derivs. Title cpds. of formula:- (where Ar = H or phenyl; R = phenyl, 1-4C alkyl, 1-4C alkenyl, 5-6C cycloalkyl; R1, R2, R3 = H, CH3 or halo) are prepd. by reaction of an isocyanate RNCO with the corresponding 3-unsubstd. oxazolidine. The cpds. have anticonvulsant, muscle relaxant, anti-depressive, anti-inflammatory, anxiolytic and analgesic activity.
Priority Applications (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7105295A FR2125175A2 (en) | 1971-02-17 | 1971-02-17 | 3-1 substd-amino-carbonyl)-5-phenyl-oxa-zoli |
| BE763964A BE763964A (en) | 1970-03-24 | 1971-03-08 | NEW DERIVATIVES OF AMINOCARBONYL-3 OXAZOLIDINONE-2, THEIR METHOD OF PREPARATION AND THEIR APPLICATION IN THERAPEUTICS |
| CH352371A CH513192A (en) | 1970-03-24 | 1971-03-10 | Process for the preparation of new derivatives of aminocarbonyl-3-oxazolidinone-2 |
| LU62777D LU62777A1 (en) | 1970-03-24 | 1971-03-11 | |
| DE19712111775 DE2111775A1 (en) | 1970-03-24 | 1971-03-11 | 3-aminocarbonyloxazolidin-2-one derivatives, process for their preparation and their use as active pharmaceutical ingredients |
| IT67963/72A IT1043850B (en) | 1970-03-24 | 1971-03-22 | GRIGINAL DERIVATIVES OF AMMINOCAPECNIL 3 GSBAZOLIDINONE 2 THEIR PREPARATION PROCEDURE AND THEIR THERAPEUTIC APPLICATION |
| US00127049A US3754000A (en) | 1970-03-24 | 1971-03-22 | Derivatives of 3-aminocarbonyl-2-oxazolidinone and their process of preparation |
| CA108,527*7A CA943553A (en) | 1970-03-24 | 1971-03-23 | Derives de l'aminocarbonyl-3 oxazolidinone-2, leur procede de preparation et leur application en therapeutique |
| ES389473A ES389473A1 (en) | 1970-03-24 | 1971-03-23 | Derivatives of 3-aminocarbonyl-2-oxazolidinone and their process of preparation |
| NL7103929A NL7103929A (en) | 1970-03-24 | 1971-03-24 | |
| JP46016770A JPS5026543B1 (en) | 1970-03-24 | 1971-03-24 | |
| GB25055/71A GB1293507A (en) | 1970-03-24 | 1971-04-19 | Derivatives of 3-carbamoyl-2-oxazolidinone, and their process of preparation |
| US344359A US3898241A (en) | 1970-03-24 | 1973-03-23 | Derivatives of 3-aminocarbonyl-2-oxazolidinone and their process of preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7105295A FR2125175A2 (en) | 1971-02-17 | 1971-02-17 | 3-1 substd-amino-carbonyl)-5-phenyl-oxa-zoli |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2125175A2 true FR2125175A2 (en) | 1972-09-29 |
| FR2125175B2 FR2125175B2 (en) | 1974-09-06 |
Family
ID=9072015
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7105295A Granted FR2125175A2 (en) | 1970-03-24 | 1971-02-17 | 3-1 substd-amino-carbonyl)-5-phenyl-oxa-zoli |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2125175A2 (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH401059A (en) * | 1961-04-04 | 1965-10-31 | Science Union & Compagnie Soci | Process for the preparation of new derivatives of Oxazolidone-2 |
-
1971
- 1971-02-17 FR FR7105295A patent/FR2125175A2/en active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH401059A (en) * | 1961-04-04 | 1965-10-31 | Science Union & Compagnie Soci | Process for the preparation of new derivatives of Oxazolidone-2 |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2125175B2 (en) | 1974-09-06 |
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