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FR2190429A1 - 5-Methoxy-2-methyl-1-phenylindole-3-carboxamides - with analgesic, antiinflammatory, anticonvulsant and other activities - Google Patents

5-Methoxy-2-methyl-1-phenylindole-3-carboxamides - with analgesic, antiinflammatory, anticonvulsant and other activities

Info

Publication number
FR2190429A1
FR2190429A1 FR7223384A FR7223384A FR2190429A1 FR 2190429 A1 FR2190429 A1 FR 2190429A1 FR 7223384 A FR7223384 A FR 7223384A FR 7223384 A FR7223384 A FR 7223384A FR 2190429 A1 FR2190429 A1 FR 2190429A1
Authority
FR
France
Prior art keywords
analgesic
phenylindole
anticonvulsant
carboxamides
antiinflammatory
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7223384A
Other languages
French (fr)
Other versions
FR2190429B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande SA filed Critical Delalande SA
Priority to FR7223384A priority Critical patent/FR2190429A1/en
Publication of FR2190429A1 publication Critical patent/FR2190429A1/en
Application granted granted Critical
Publication of FR2190429B1 publication Critical patent/FR2190429B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

Cpds of formula where R is C1-C4 alkylamino, an opt subst pyrrolidino, piperidino, morpholino, hexamethyleneimino, and piperazino substd. in the 4-position by pyrrolidino-carbonylmenthyl, isopropylaminocarbonylmethyl, morpholinocarbonylmethyl, ethoxycarbonylmethyl, ethoxycarbonylmethyl. The cpds have analgesic, antiflammatory, hypotensive, vasodilator, anticonoulsant, anxiolytic, sedative, anticholinergic, bronchodilator and antibradycardia activity. The daily does is 1-5 oral dosage units daily, each contg. 50-3000 mg of I; or 1-2 suppositiones daily each contg. 50-250 mg of I.
FR7223384A 1972-06-28 1972-06-28 5-Methoxy-2-methyl-1-phenylindole-3-carboxamides - with analgesic, antiinflammatory, anticonvulsant and other activities Granted FR2190429A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7223384A FR2190429A1 (en) 1972-06-28 1972-06-28 5-Methoxy-2-methyl-1-phenylindole-3-carboxamides - with analgesic, antiinflammatory, anticonvulsant and other activities

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7223384A FR2190429A1 (en) 1972-06-28 1972-06-28 5-Methoxy-2-methyl-1-phenylindole-3-carboxamides - with analgesic, antiinflammatory, anticonvulsant and other activities

Publications (2)

Publication Number Publication Date
FR2190429A1 true FR2190429A1 (en) 1974-02-01
FR2190429B1 FR2190429B1 (en) 1975-06-20

Family

ID=9100994

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7223384A Granted FR2190429A1 (en) 1972-06-28 1972-06-28 5-Methoxy-2-methyl-1-phenylindole-3-carboxamides - with analgesic, antiinflammatory, anticonvulsant and other activities

Country Status (1)

Country Link
FR (1) FR2190429A1 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3466287A (en) * 1966-10-07 1969-09-09 Sterling Drug Inc 1-((3-indolyl)-lower-alkyl)-4-substituted piperazines
FR2092704A1 (en) * 1970-06-10 1972-01-28 Delalande Sa
GB1273563A (en) * 1968-07-24 1972-05-10 Wyeth John & Brother Ltd Indoles

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3466287A (en) * 1966-10-07 1969-09-09 Sterling Drug Inc 1-((3-indolyl)-lower-alkyl)-4-substituted piperazines
GB1273563A (en) * 1968-07-24 1972-05-10 Wyeth John & Brother Ltd Indoles
FR2092704A1 (en) * 1970-06-10 1972-01-28 Delalande Sa

Also Published As

Publication number Publication date
FR2190429B1 (en) 1975-06-20

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Legal Events

Date Code Title Description
ST Notification of lapse