|
WO2012088266A2
(en)
|
2010-12-22 |
2012-06-28 |
Incyte Corporation |
Substituted imidazopyridazines and benzimidazoles as inhibitors of fgfr3
|
|
JP5873656B2
(ja)
|
2011-06-13 |
2016-03-01 |
株式会社Ihi |
金属サレン錯体化合物、局所麻酔薬剤及び抗悪性腫瘍薬剤
|
|
ES2984771T3
(es)
|
2012-06-13 |
2024-10-31 |
Incyte Holdings Corp |
Compuestos tricíclicos sustituidos como inhibidores de FGFR
|
|
RU2019102203A
(ru)
|
2012-07-11 |
2019-03-05 |
Блюпринт Медсинс Корпорейшн |
Ингибиторы рецептора фактора роста фибробластов
|
|
WO2014026125A1
(en)
|
2012-08-10 |
2014-02-13 |
Incyte Corporation |
Pyrazine derivatives as fgfr inhibitors
|
|
US9266892B2
(en)
|
2012-12-19 |
2016-02-23 |
Incyte Holdings Corporation |
Fused pyrazoles as FGFR inhibitors
|
|
AR094812A1
(es)
|
2013-02-20 |
2015-08-26 |
Eisai R&D Man Co Ltd |
Derivado de piridina monocíclico como inhibidor del fgfr
|
|
EA035095B1
(ru)
|
2013-04-19 |
2020-04-27 |
Инсайт Холдингс Корпорейшн |
Бициклические гетероциклы в качестве ингибиторов fgfr
|
|
ES2819398T3
(es)
*
|
2013-07-18 |
2021-04-15 |
Taiho Pharmaceutical Co Ltd |
Agente terapéutico para el cáncer resistente al inhibidor de FGFR
|
|
TWI574691B
(zh)
*
|
2013-07-18 |
2017-03-21 |
Taiho Pharmaceutical Co Ltd |
Anti - tumor agents for intermittent administration of FGFR inhibitors
|
|
CA2921208C
(en)
|
2013-08-12 |
2018-02-20 |
Taiho Pharmaceutical Co., Ltd. |
Fused pyrimidine compound or salt thereof
|
|
PT3395814T
(pt)
|
2013-10-25 |
2022-07-27 |
Blueprint Medicines Corp |
Inibidores do recetor do fator de crescimento de fibroblastos
|
|
JP6514645B2
(ja)
|
2013-12-27 |
2019-05-15 |
中外製薬株式会社 |
Ｆｇｆｒゲートキーパー変異遺伝子およびそれを標的とする医薬
|
|
WO2015108992A1
(en)
|
2014-01-15 |
2015-07-23 |
Blueprint Medicines Corporation |
Heterobicyclic compounds and their use as fgfr4 receptor inhibitors
|
|
PT3103802T
(pt)
*
|
2014-06-24 |
2017-12-11 |
Taiho Pharmaceutical Co Ltd |
Novo composto de pirrolopirimidina ou seu sal, composição farmacêutica que o contém, especialmente agente para prevenção e/ou tratamento de tumores etc. com base no efeito inibidor de nae
|
|
US9951047B2
(en)
|
2014-08-18 |
2018-04-24 |
Eisai R&D Management Co., Ltd. |
Salt of monocyclic pyridine derivative and crystal thereof
|
|
US10851105B2
(en)
|
2014-10-22 |
2020-12-01 |
Incyte Corporation |
Bicyclic heterocycles as FGFR4 inhibitors
|
|
CN105837575B
(zh)
*
|
2015-01-13 |
2019-01-15 |
四川大学 |
3-乙炔基吡唑并嘧啶衍生物及其制备方法和用途
|
|
TWI638817B
(zh)
*
|
2015-01-30 |
2018-10-21 |
大鵬藥品工業股份有限公司 |
免疫疾病之預防及／或治療劑
|
|
MA41551A
(fr)
|
2015-02-20 |
2017-12-26 |
Incyte Corp |
Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
|
|
US9580423B2
(en)
|
2015-02-20 |
2017-02-28 |
Incyte Corporation |
Bicyclic heterocycles as FGFR4 inhibitors
|
|
EA038045B1
(ru)
|
2015-02-20 |
2021-06-28 |
Инсайт Корпорейшн |
Бициклические гетероциклы в качестве ингибиторов fgfr
|
|
EP3275442B1
(en)
|
2015-03-25 |
2021-07-28 |
National Cancer Center |
Therapeutic agent for bile duct cancer
|
|
CN111393446B
(zh)
*
|
2015-03-31 |
2022-12-20 |
大鹏药品工业株式会社 |
3,5-二取代的苯炔基化合物晶体
|
|
US10479780B2
(en)
|
2015-06-17 |
2019-11-19 |
Chugai Seiyaku Kabushiki Kaisha |
Aminopyrazole derivatives
|
|
EP3345907B1
(en)
*
|
2015-09-01 |
2020-04-22 |
Taiho Pharmaceutical Co., Ltd. |
Pyrazolo[3,4-d]pyrimidine compounds or salts thereof
|
|
WO2017104739A1
(ja)
|
2015-12-17 |
2017-06-22 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
乳がん治療剤
|
|
TWI623316B
(zh)
*
|
2015-12-22 |
2018-05-11 |
Taiho Pharmaceutical Co Ltd |
Antitumor effect enhancer derived from pyrrolopyrimidine compound
|
|
HRP20200352T1
(hr)
*
|
2016-02-23 |
2020-06-12 |
Taiho Pharmaceutical Co., Ltd. |
Novi kondenzirani pirimidinski spoj ili njegova sol
|
|
US11883404B2
(en)
*
|
2016-03-04 |
2024-01-30 |
Taiho Pharmaceuticals Co., Ltd. |
Preparation and composition for treatment of malignant tumors
|
|
KR20220110859A
(ko)
*
|
2016-03-04 |
2022-08-09 |
다이호야쿠힌고교 가부시키가이샤 |
악성 종양 치료용 제제 및 조성물
|
|
CN107344940B
(zh)
*
|
2016-05-06 |
2020-04-21 |
广东东阳光药业有限公司 |
Btk抑制剂及其用途
|
|
CN107698593A
(zh)
*
|
2016-08-09 |
2018-02-16 |
南京天印健华医药科技有限公司 |
作为fgfr抑制剂的杂环化合物
|
|
MA47696A
(fr)
*
|
2017-02-28 |
2020-01-08 |
Taiho Pharmaceutical Co Ltd |
Activateur d'effet antitumoral utilisant un composé pyrazolo[3,4-d]pyrimidine
|
|
AR111960A1
(es)
|
2017-05-26 |
2019-09-04 |
Incyte Corp |
Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
|
|
JOP20180094A1
(ar)
|
2017-10-18 |
2019-04-18 |
Hk Inno N Corp |
مركب حلقي غير متجانس كمثبط بروتين كيناز
|
|
CN109776544B
(zh)
*
|
2017-11-15 |
2022-02-01 |
上海医药工业研究院 |
吡唑并[3,4-d]嘧啶类化合物及其制备方法和用途
|
|
RU2759746C1
(ru)
|
2018-03-19 |
2021-11-17 |
Тайхо Фармасьютикал Ко., Лтд. |
Фармацевтическая композиция, включающая алкилсульфат натрия
|
|
BR112020017922A2
(pt)
|
2018-03-28 |
2020-12-22 |
Eisai R&D Management Co., Ltd. |
Agente terapêutico para carcinoma hepatocelular
|
|
US11174257B2
(en)
|
2018-05-04 |
2021-11-16 |
Incyte Corporation |
Salts of an FGFR inhibitor
|
|
RS66310B1
(sr)
|
2018-05-04 |
2025-01-31 |
Incyte Corp |
Čvrsti oblici inhibitora fgfr i procesi za njegovu pripremu
|
|
JP7162372B2
(ja)
|
2018-07-02 |
2022-10-28 |
深▲チェン▼市塔吉瑞生物医薬有限公司 |
キナーゼ活性を阻害するためのアルキニル（ヘテロ）芳香族化合物
|
|
WO2020096050A1
(ja)
|
2018-11-09 |
2020-05-14 |
大鵬薬品工業株式会社 |
ジメトキシベンゼン化合物の類縁物質、該化合物の分析方法及び標準品
|
|
WO2020095452A1
(ja)
*
|
2018-11-09 |
2020-05-14 |
大鵬薬品工業株式会社 |
ジメトキシベンゼン化合物の製造方法
|
|
KR102195348B1
(ko)
|
2018-11-15 |
2020-12-24 |
에이치케이이노엔 주식회사 |
단백질 키나제 억제제로서의 신규 화합물 및 이를 포함하는 약제학적 조성물
|
|
EP3888643A4
(en)
*
|
2018-11-26 |
2022-08-24 |
Taiho Pharmaceutical Co., Ltd. |
Therapeutic and prophylactic method for tumor treatable with endocrine therapy by combined use of fibroblast growth factor receptor inhibitor with endocrine therapy
|
|
WO2020170355A1
(ja)
*
|
2019-02-20 |
2020-08-27 |
大鵬薬品工業株式会社 |
Ｆｇｆｒ１変異腫瘍の治療方法
|
|
WO2020175704A1
(ja)
*
|
2019-02-28 |
2020-09-03 |
大鵬薬品工業株式会社 |
３，５－二置換ベンゼンアルキニル化合物と免疫チェックポイント阻害薬とを用いた癌治療法
|
|
WO2020185532A1
(en)
|
2019-03-08 |
2020-09-17 |
Incyte Corporation |
Methods of treating cancer with an fgfr inhibitor
|
|
KR20210142154A
(ko)
|
2019-03-21 |
2021-11-24 |
옹쎄오 |
암 치료를 위한 키나제 억제제와 조합된 dbait 분자
|
|
MX2021013146A
(es)
*
|
2019-05-13 |
2022-01-24 |
Relay Therapeutics Inc |
Inhibidores de receptores del factor de crecimiento de fibroblastos (fgfr) y metodos de uso de los mismos.
|
|
CA3139161A1
(en)
*
|
2019-05-17 |
2020-11-26 |
Kinnate Biopharma Inc. |
Inhibitors of fibroblast growth factor receptor kinases
|
|
EP3988175A4
(en)
|
2019-06-21 |
2023-06-28 |
Taiho Pharmaceutical Co., Ltd. |
Method for treating malignant tumor
|
|
WO2021007269A1
(en)
|
2019-07-09 |
2021-01-14 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
WO2021067374A1
(en)
|
2019-10-01 |
2021-04-08 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
PH12022550892A1
(en)
|
2019-10-14 |
2023-05-03 |
Incyte Corp |
Bicyclic heterocycles as fgfr inhibitors
|
|
US11566028B2
(en)
|
2019-10-16 |
2023-01-31 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
CN114761006A
(zh)
|
2019-11-08 |
2022-07-15 |
Inserm(法国国家健康医学研究院) |
对激酶抑制剂产生耐药性的癌症的治疗方法
|
|
CN114641293B
(zh)
*
|
2019-11-08 |
2024-05-31 |
石药集团中奇制药技术（石家庄）有限公司 |
一种fgfr抑制剂的用途
|
|
AU2020395185A1
(en)
|
2019-12-04 |
2022-06-02 |
Incyte Corporation |
Derivatives of an FGFR inhibitor
|
|
EP4069696A1
(en)
|
2019-12-04 |
2022-10-12 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
US12012409B2
(en)
|
2020-01-15 |
2024-06-18 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
WO2021148581A1
(en)
|
2020-01-22 |
2021-07-29 |
Onxeo |
Novel dbait molecule and its use
|
|
EP4098263A4
(en)
|
2020-01-31 |
2024-03-20 |
Kyoto University |
TREATMENT FOR CHONDRODYSTROPHY
|
|
CN116057045A
(zh)
|
2020-06-05 |
2023-05-02 |
金耐特生物制药公司 |
成纤维细胞生长因子受体激酶抑制剂
|
|
EP4183395A4
(en)
*
|
2020-07-15 |
2024-07-24 |
Taiho Pharmaceutical Co., Ltd. |
PYRIMIDINE COMPOUND-CONTAINING COMBINATION FOR USE IN TUMOR TREATMENT
|
|
TWI797711B
(zh)
*
|
2020-08-13 |
2023-04-01 |
大陸商上海和譽生物醫藥科技有限公司 |
一種fgfr及其突變抑制劑，其製備方法和應用
|
|
CN115867547B
(zh)
*
|
2020-08-27 |
2024-12-20 |
上海和誉生物医药科技有限公司 |
一种1h-吡唑-4-酰胺衍生物，其制备方法和应用
|
|
TW202233625A
(zh)
|
2020-11-18 |
2022-09-01 |
美商傳達治療有限公司 |
Ｆｇｆｒ抑制劑及其製造及使用方法
|
|
CA3199714A1
(en)
*
|
2020-11-20 |
2022-05-27 |
Isao Miyazaki |
Brain-migrating tumor therapeutic agent containing fused pyrimidine compound as active ingredient
|
|
CN114805359B
(zh)
*
|
2021-01-28 |
2023-10-27 |
药雅科技(上海)有限公司 |
炔代杂环化合物fgfr抑制剂的制备方法和用途
|
|
CN115028634B
(zh)
*
|
2021-03-08 |
2023-11-28 |
药雅科技(上海)有限公司 |
一种炔代吡嗪并杂环类fgfr抑制剂及其制备方法和用途
|
|
KR20230170668A
(ko)
*
|
2021-03-08 |
2023-12-19 |
다이호야쿠힌고교 가부시키가이샤 |
Fgfr2 및 암 유발 유전자의 동시발생 유전자 변형이 있는 환자의 암 치료
|
|
JP2024513575A
(ja)
|
2021-04-12 |
2024-03-26 |
インサイト・コーポレイション |
Ｆｇｆｒ阻害剤及びネクチン－４標的化剤を含む併用療法
|
|
WO2022261160A1
(en)
|
2021-06-09 |
2022-12-15 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
TW202313610A
(zh)
|
2021-06-09 |
2023-04-01 |
美商英塞特公司 |
作為ｆｇｆｒ抑制劑之三環雜環
|
|
CN115785103A
(zh)
*
|
2022-12-28 |
2023-03-14 |
北京康立生医药技术开发有限公司 |
一种治疗胆管癌药物福巴替尼的合成方法
|
|
WO2025178019A1
(ja)
*
|
2024-02-19 |
2025-08-28 |
国立大学法人大阪大学 |
繊毛病治療用医薬組成物
|
|
CN119080780A
(zh)
*
|
2024-08-29 |
2024-12-06 |
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|
|
CN120172981B
(zh)
*
|
2025-05-20 |
2025-07-25 |
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|