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FI974578L - Förfarande för givande av levosimendan - Google Patents

Förfarande för givande av levosimendan Download PDF

Info

Publication number
FI974578L
FI974578L FI974578A FI974578A FI974578L FI 974578 L FI974578 L FI 974578L FI 974578 A FI974578 A FI 974578A FI 974578 A FI974578 A FI 974578A FI 974578 L FI974578 L FI 974578L
Authority
FI
Finland
Prior art keywords
levosimendan
administration
Prior art date
Application number
FI974578A
Other languages
English (en)
Finnish (fi)
Other versions
FI974578A7 (sv
FI974578A0 (fi
Inventor
Kauko Kurkela
Martti Marvola
Ilkka Larma
Raimo Virtanen
Marianne Karlsson
Original Assignee
Orion Yhtymae Oyj
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtymae Oyj filed Critical Orion Yhtymae Oyj
Priority to FI974578A priority Critical patent/FI974578A7/sv
Publication of FI974578A0 publication Critical patent/FI974578A0/fi
Priority to BR9813641-0A priority patent/BR9813641A/pt
Priority to EEP200000368A priority patent/EE04330B1/xx
Priority to HR20000400A priority patent/HRP20000400B1/xx
Priority to PCT/FI1998/000977 priority patent/WO1999032081A1/en
Priority to ES98959930T priority patent/ES2175827T3/es
Priority to AU15656/99A priority patent/AU738082B2/en
Priority to SK906-2000A priority patent/SK284838B6/sk
Priority to KR1020007006835A priority patent/KR100753689B1/ko
Priority to JP2000525076A priority patent/JP2001526205A/ja
Priority to ZA9811405A priority patent/ZA9811405B/xx
Priority to CA002313618A priority patent/CA2313618C/en
Priority to PT98959930T priority patent/PT1052973E/pt
Priority to HU0100452A priority patent/HU226736B1/hu
Priority to DK98959930T priority patent/DK1052973T3/da
Priority to DE69804678T priority patent/DE69804678T2/de
Priority to SI9830182T priority patent/SI1052973T1/xx
Priority to EA200000686A priority patent/EA002197B1/ru
Priority to US09/581,610 priority patent/US6399610B1/en
Priority to YUP-369/00A priority patent/RS49889B/sr
Priority to NZ504806A priority patent/NZ504806A/en
Priority to CZ20002155A priority patent/CZ296693B6/cs
Priority to PL341202A priority patent/PL191868B1/pl
Priority to IL13641598A priority patent/IL136415A/xx
Priority to AT98959930T priority patent/ATE215358T1/de
Priority to EP98959930A priority patent/EP1052973B1/en
Publication of FI974578L publication Critical patent/FI974578L/sv
Publication of FI974578A7 publication Critical patent/FI974578A7/sv
Priority to NO20003059A priority patent/NO320050B1/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Physiology (AREA)
  • Urology & Nephrology (AREA)
  • Nutrition Science (AREA)
  • Otolaryngology (AREA)
  • Cardiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Paper (AREA)
  • Air Bags (AREA)
  • Luminescent Compositions (AREA)
FI974578A 1997-12-19 1997-12-19 Förfarande för givande av levosimendan FI974578A7 (sv)

Priority Applications (27)

Application Number Priority Date Filing Date Title
FI974578A FI974578A7 (sv) 1997-12-19 1997-12-19 Förfarande för givande av levosimendan
EP98959930A EP1052973B1 (en) 1997-12-19 1998-12-11 Transmucosal formulations of levosimendan
PT98959930T PT1052973E (pt) 1997-12-19 1998-12-11 Formulacoes transmucosais de levosimendano
DK98959930T DK1052973T3 (da) 1997-12-19 1998-12-11 Transmucosale formuleringer af levosimendan
HR20000400A HRP20000400B1 (hr) 1997-12-19 1998-12-11 Transmukozni pripravci levosimendana
PCT/FI1998/000977 WO1999032081A1 (en) 1997-12-19 1998-12-11 Transmucosal formulations of levosimendan
ES98959930T ES2175827T3 (es) 1997-12-19 1998-12-11 Formulaciones transmucosas de levosimendano.
AU15656/99A AU738082B2 (en) 1997-12-19 1998-12-11 Transmucosal formulations of levosimendan
SK906-2000A SK284838B6 (sk) 1997-12-19 1998-12-11 Farmaceutický prípravok obsahujúci levosimendán a použitie levosimendánu na výrobu lieku
KR1020007006835A KR100753689B1 (ko) 1997-12-19 1998-12-11 레보시멘단의 점막투여 제형
JP2000525076A JP2001526205A (ja) 1997-12-19 1998-12-11 レボシメンダンの粘膜透過的処方
ZA9811405A ZA9811405B (en) 1997-12-19 1998-12-11 A method for administration of levosimendan
CA002313618A CA2313618C (en) 1997-12-19 1998-12-11 Transmucosal formulations of levosimendan
BR9813641-0A BR9813641A (pt) 1997-12-19 1998-12-11 "preparados transmucosais de levosimendan"
HU0100452A HU226736B1 (en) 1997-12-19 1998-12-11 Transmucosal formulations of levosimendan
EEP200000368A EE04330B1 (et) 1997-12-19 1998-12-11 Levosimendani transmukoossed koostised ja nende kasutamine ravimi valmistamiseks
DE69804678T DE69804678T2 (de) 1997-12-19 1998-12-11 Transmukosale levosimendanformulierungen
SI9830182T SI1052973T1 (en) 1997-12-19 1998-12-11 Transmucosal formulations of levosimendan
EA200000686A EA002197B1 (ru) 1997-12-19 1998-12-11 Препараты левозимендана, предназначенные для введения через слизистую оболочку
US09/581,610 US6399610B1 (en) 1997-12-19 1998-12-11 Transmucosal formulations of levosimendan
YUP-369/00A RS49889B (sr) 1997-12-19 1998-12-11 Intraoralni ili intranazalni transmukozni preparat koji sadrži levosimendan
NZ504806A NZ504806A (en) 1997-12-19 1998-12-11 Transmucosal formulations of levosimendan
CZ20002155A CZ296693B6 (cs) 1997-12-19 1998-12-11 Transmukozální preparáty s levosimendanem
PL341202A PL191868B1 (pl) 1997-12-19 1998-12-11 Zastosowanie lewosimendanu do wytwarzania preparatu do podawania przez błonę śluzową
IL13641598A IL136415A (en) 1997-12-19 1998-12-11 Transmucosal formulations of levosimendan
AT98959930T ATE215358T1 (de) 1997-12-19 1998-12-11 Transmukosale levosimendanformulierungen
NO20003059A NO320050B1 (no) 1997-12-19 2000-06-14 Transmukosale formuleringer av levosimendan og anvendelse derav til fremstilling av faramasoytisk preparat.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI974578A FI974578A7 (sv) 1997-12-19 1997-12-19 Förfarande för givande av levosimendan

Publications (3)

Publication Number Publication Date
FI974578A0 FI974578A0 (fi) 1997-12-19
FI974578L true FI974578L (sv) 1999-06-20
FI974578A7 FI974578A7 (sv) 1999-06-20

Family

ID=8550178

Family Applications (1)

Application Number Title Priority Date Filing Date
FI974578A FI974578A7 (sv) 1997-12-19 1997-12-19 Förfarande för givande av levosimendan

Country Status (26)

Country Link
US (1) US6399610B1 (sv)
EP (1) EP1052973B1 (sv)
JP (1) JP2001526205A (sv)
KR (1) KR100753689B1 (sv)
AT (1) ATE215358T1 (sv)
AU (1) AU738082B2 (sv)
BR (1) BR9813641A (sv)
CA (1) CA2313618C (sv)
CZ (1) CZ296693B6 (sv)
DE (1) DE69804678T2 (sv)
DK (1) DK1052973T3 (sv)
EA (1) EA002197B1 (sv)
EE (1) EE04330B1 (sv)
ES (1) ES2175827T3 (sv)
FI (1) FI974578A7 (sv)
HR (1) HRP20000400B1 (sv)
HU (1) HU226736B1 (sv)
IL (1) IL136415A (sv)
NO (1) NO320050B1 (sv)
NZ (1) NZ504806A (sv)
PL (1) PL191868B1 (sv)
PT (1) PT1052973E (sv)
RS (1) RS49889B (sv)
SK (1) SK284838B6 (sv)
WO (1) WO1999032081A1 (sv)
ZA (1) ZA9811405B (sv)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI980901A7 (sv) * 1998-04-23 1999-10-24 Orion Yhtymae Oyj Orala sammansättningar som kontrollerat frigör levosimendan
FI20002755A0 (sv) 2000-12-15 2000-12-15 Orion Yhtymae Oyj Method för terapi av erektil dysfunktion
CN100428937C (zh) * 2003-10-30 2008-10-29 北京海合天科技开发有限公司 左西孟旦冷冻干燥组合物
FI20040674A0 (sv) * 2004-05-12 2004-05-12 Orion Corp Metod för förebyggandet av tromboemboliska sjukdomar
EP2767163A1 (en) * 2005-02-17 2014-08-20 Abbott Laboratories Transmucosal administration of drug compositions for treating and preventing disorders in animals
US20070032557A1 (en) * 2005-02-18 2007-02-08 Matti Kivikko Method for administering levosimendan
WO2007096906A2 (en) * 2006-02-27 2007-08-30 Panacea Biotec Ltd. Novel buccoadhesive compositions and process of preparation thereof
US10092715B2 (en) * 2006-09-27 2018-10-09 Niconovum Usa, Inc. Directional use
US20220160656A1 (en) * 2019-03-22 2022-05-26 Dbbh, Llc Intranasally administered antihistamines and uses thereof
EP3993773A1 (en) * 2019-07-01 2022-05-11 Orion Corporation Methods for administering (r)-n-[4-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)phenyl]acetamide
EP4076398A4 (en) 2019-12-16 2024-01-03 Tenax Therapeutics, Inc. LEVOSIMENDAN TO TREAT PULMONARY HYPERTENSION ACCOMPANIED BY HEART FAILURE BY MEANS OF PRESERVED EJECTION FRACTION (PH-HF-PEF)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2251615B (en) 1991-01-03 1995-02-08 Orion Yhtymae Oy (-)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]hydrazono]pro panedinitrile
GB2266841A (en) * 1992-05-06 1993-11-17 Orion Yhtymae Oy Compounds for use as anti-ischemic medicaments
US5688520A (en) * 1995-03-29 1997-11-18 Minnesota Mining And Manufacturing Company Transmucosal delivery of melatonin for prevention of migraine
GB9614098D0 (en) * 1996-07-05 1996-09-04 Orion Yhtymae Oy Transdermal delivery of levosimendan

Also Published As

Publication number Publication date
HRP20000400A2 (en) 2000-12-31
US6399610B1 (en) 2002-06-04
PL341202A1 (en) 2001-03-26
BR9813641A (pt) 2000-10-17
EE04330B1 (et) 2004-08-16
NO320050B1 (no) 2005-10-17
IL136415A (en) 2005-03-20
AU1565699A (en) 1999-07-12
FI974578A7 (sv) 1999-06-20
DK1052973T3 (da) 2002-04-29
HUP0100452A3 (en) 2002-03-28
RS49889B (sr) 2008-08-07
KR20010033368A (ko) 2001-04-25
KR100753689B1 (ko) 2007-08-30
NZ504806A (en) 2001-09-28
HRP20000400B1 (hr) 2009-06-30
EP1052973A1 (en) 2000-11-22
WO1999032081A1 (en) 1999-07-01
HU226736B1 (en) 2009-08-28
EE200000368A (et) 2001-10-15
NO20003059L (no) 2000-06-14
JP2001526205A (ja) 2001-12-18
EA002197B1 (ru) 2002-02-28
SK284838B6 (sk) 2005-12-01
SK9062000A3 (en) 2000-12-11
YU36900A (sh) 2003-02-28
ZA9811405B (en) 1999-06-11
EA200000686A1 (ru) 2000-12-25
DE69804678D1 (de) 2002-05-08
ATE215358T1 (de) 2002-04-15
IL136415A0 (en) 2001-06-14
CA2313618A1 (en) 1999-07-01
NO20003059D0 (no) 2000-06-14
FI974578A0 (fi) 1997-12-19
CA2313618C (en) 2008-02-05
EP1052973B1 (en) 2002-04-03
CZ296693B6 (cs) 2006-05-17
PT1052973E (pt) 2002-09-30
HUP0100452A2 (hu) 2002-02-28
AU738082B2 (en) 2001-09-06
ES2175827T3 (es) 2002-11-16
DE69804678T2 (de) 2002-11-21
PL191868B1 (pl) 2006-07-31
CZ20002155A3 (cs) 2000-11-15

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