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ES2175827T3 - Formulaciones transmucosas de levosimendano. - Google Patents

Formulaciones transmucosas de levosimendano.

Info

Publication number
ES2175827T3
ES2175827T3 ES98959930T ES98959930T ES2175827T3 ES 2175827 T3 ES2175827 T3 ES 2175827T3 ES 98959930 T ES98959930 T ES 98959930T ES 98959930 T ES98959930 T ES 98959930T ES 2175827 T3 ES2175827 T3 ES 2175827T3
Authority
ES
Spain
Prior art keywords
levosimendano
transmucous
formulations
pharmaceutically acceptable
intraoral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98959930T
Other languages
English (en)
Inventor
Kauko Kurkela
Martti Marvola
Ilkka Larma
Raimo Virtanen
Marianne Karlsson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orion Oyj
Original Assignee
Orion Oyj
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Oyj filed Critical Orion Oyj
Application granted granted Critical
Publication of ES2175827T3 publication Critical patent/ES2175827T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • Otolaryngology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Luminescent Compositions (AREA)
  • Paper (AREA)
  • Air Bags (AREA)

Abstract

Una preparación transmucosa intraoral o intranasal que comprende levosimendano o una sal farmacéuticamente aceptable del mismo como un ingrediente terapéuticamente activo, junto con uno o más excipientes farmacéuticamente aceptables.
ES98959930T 1997-12-19 1998-12-11 Formulaciones transmucosas de levosimendano. Expired - Lifetime ES2175827T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI974578A FI974578L (fi) 1997-12-19 1997-12-19 Menetelmä levosimendaanin antamiseksi

Publications (1)

Publication Number Publication Date
ES2175827T3 true ES2175827T3 (es) 2002-11-16

Family

ID=8550178

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98959930T Expired - Lifetime ES2175827T3 (es) 1997-12-19 1998-12-11 Formulaciones transmucosas de levosimendano.

Country Status (26)

Country Link
US (1) US6399610B1 (es)
EP (1) EP1052973B1 (es)
JP (1) JP2001526205A (es)
KR (1) KR100753689B1 (es)
AT (1) ATE215358T1 (es)
AU (1) AU738082B2 (es)
BR (1) BR9813641A (es)
CA (1) CA2313618C (es)
CZ (1) CZ296693B6 (es)
DE (1) DE69804678T2 (es)
DK (1) DK1052973T3 (es)
EA (1) EA002197B1 (es)
EE (1) EE04330B1 (es)
ES (1) ES2175827T3 (es)
FI (1) FI974578L (es)
HR (1) HRP20000400B1 (es)
HU (1) HU226736B1 (es)
IL (1) IL136415A (es)
NO (1) NO320050B1 (es)
NZ (1) NZ504806A (es)
PL (1) PL191868B1 (es)
PT (1) PT1052973E (es)
RS (1) RS49889B (es)
SK (1) SK284838B6 (es)
WO (1) WO1999032081A1 (es)
ZA (1) ZA9811405B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI980901A7 (fi) * 1998-04-23 1999-10-24 Orion Yhtymae Oyj Levosimendaania säädellysti vapauttavia oraalisia koostumuksia
FI20002755A0 (fi) 2000-12-15 2000-12-15 Orion Yhtymae Oyj Menetelmä erektiilin dysfunktion hoitamiseen
CN100428937C (zh) * 2003-10-30 2008-10-29 北京海合天科技开发有限公司 左西孟旦冷冻干燥组合物
FI20040674A0 (fi) 2004-05-12 2004-05-12 Orion Corp Menetelmä tromboembolisten sairauksien estoon
JP5577021B2 (ja) * 2005-02-17 2014-08-20 アボット・ラボラトリーズ 動物における障害を治療および予防するための薬剤組成物の経粘膜投与
CA2596768A1 (en) * 2005-02-18 2006-08-24 Orion Corporation A method for treating heart failure
WO2007096906A2 (en) * 2006-02-27 2007-08-30 Panacea Biotec Ltd. Novel buccoadhesive compositions and process of preparation thereof
KR20090055606A (ko) 2006-09-27 2009-06-02 니코노범 에이비 지향성 용도
WO2020197918A1 (en) * 2019-03-22 2020-10-01 Dbbh, Llc Intranasally administered antihistamines and uses thereof
CA3145456A1 (en) * 2019-07-01 2021-01-07 Orion Corporation Methods for administering (r)-n-[4-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)phenyl]acetamide
AU2020408323A1 (en) 2019-12-16 2022-08-11 Tenax Therapeutics, Inc. Levosimendan for treating pulmonary hypertension with heart failure with preserved ejection fraction (PH-HF-pEF)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2251615B (en) * 1991-01-03 1995-02-08 Orion Yhtymae Oy (-)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]hydrazono]pro panedinitrile
GB2266841A (en) * 1992-05-06 1993-11-17 Orion Yhtymae Oy Compounds for use as anti-ischemic medicaments
US5688520A (en) * 1995-03-29 1997-11-18 Minnesota Mining And Manufacturing Company Transmucosal delivery of melatonin for prevention of migraine
GB9614098D0 (en) * 1996-07-05 1996-09-04 Orion Yhtymae Oy Transdermal delivery of levosimendan

Also Published As

Publication number Publication date
HUP0100452A2 (hu) 2002-02-28
PL341202A1 (en) 2001-03-26
HRP20000400B1 (hr) 2009-06-30
SK9062000A3 (en) 2000-12-11
BR9813641A (pt) 2000-10-17
NO20003059D0 (no) 2000-06-14
JP2001526205A (ja) 2001-12-18
DE69804678D1 (de) 2002-05-08
HU226736B1 (en) 2009-08-28
PL191868B1 (pl) 2006-07-31
CZ20002155A3 (cs) 2000-11-15
YU36900A (sh) 2003-02-28
ZA9811405B (en) 1999-06-11
NO320050B1 (no) 2005-10-17
EP1052973B1 (en) 2002-04-03
NZ504806A (en) 2001-09-28
EA200000686A1 (ru) 2000-12-25
FI974578A7 (fi) 1999-06-20
FI974578L (fi) 1999-06-20
EE04330B1 (et) 2004-08-16
PT1052973E (pt) 2002-09-30
KR20010033368A (ko) 2001-04-25
DK1052973T3 (da) 2002-04-29
EA002197B1 (ru) 2002-02-28
CA2313618A1 (en) 1999-07-01
WO1999032081A1 (en) 1999-07-01
CA2313618C (en) 2008-02-05
NO20003059L (no) 2000-06-14
US6399610B1 (en) 2002-06-04
ATE215358T1 (de) 2002-04-15
AU1565699A (en) 1999-07-12
AU738082B2 (en) 2001-09-06
EE200000368A (et) 2001-10-15
SK284838B6 (sk) 2005-12-01
HUP0100452A3 (en) 2002-03-28
HRP20000400A2 (en) 2000-12-31
IL136415A (en) 2005-03-20
EP1052973A1 (en) 2000-11-22
CZ296693B6 (cs) 2006-05-17
DE69804678T2 (de) 2002-11-21
KR100753689B1 (ko) 2007-08-30
IL136415A0 (en) 2001-06-14
RS49889B (sr) 2008-08-07
FI974578A0 (fi) 1997-12-19

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