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FI961900L - Method for preparing a virus-inactivated, factor VIII-containing fraction by chromatographic methods - Google Patents

Method for preparing a virus-inactivated, factor VIII-containing fraction by chromatographic methods Download PDF

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Publication number
FI961900L
FI961900L FI961900A FI961900A FI961900L FI 961900 L FI961900 L FI 961900L FI 961900 A FI961900 A FI 961900A FI 961900 A FI961900 A FI 961900A FI 961900 L FI961900 L FI 961900L
Authority
FI
Finland
Prior art keywords
inactivated
virus
preparing
factor viii
chromatographic methods
Prior art date
Application number
FI961900A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI116569B (en
FI961900A0 (en
Inventor
Ales Strancar
Monika Andrea Stadler
Djuro Josic
Original Assignee
Octapharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6501733&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI961900(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Octapharma Ag filed Critical Octapharma Ag
Publication of FI961900A0 publication Critical patent/FI961900A0/en
Publication of FI961900L publication Critical patent/FI961900L/en
Application granted granted Critical
Publication of FI116569B publication Critical patent/FI116569B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI961900A 1993-11-04 1996-05-03 Process for Preparation of Virus Inactivated Factor VIII Containing Fraction by Chromatographic Procedures FI116569B (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE4337573 1993-11-04
DE4337573A DE4337573C1 (en) 1993-11-04 1993-11-04 Process for the preparation of a virus-inactivated factor VIII-containing fraction by means of chromatographic methods
PCT/EP1994/003258 WO1995012609A1 (en) 1993-11-04 1994-09-30 Process for producing a virus-inactivated factor viii-containing fraction by chromatographic methods
EP9403258 1994-09-30

Publications (3)

Publication Number Publication Date
FI961900A0 FI961900A0 (en) 1996-05-03
FI961900L true FI961900L (en) 1996-05-03
FI116569B FI116569B (en) 2005-12-30

Family

ID=6501733

Family Applications (1)

Application Number Title Priority Date Filing Date
FI961900A FI116569B (en) 1993-11-04 1996-05-03 Process for Preparation of Virus Inactivated Factor VIII Containing Fraction by Chromatographic Procedures

Country Status (21)

Country Link
EP (1) EP0726907B1 (en)
JP (1) JP3739788B2 (en)
KR (1) KR960705841A (en)
CN (1) CN1109045C (en)
AT (1) ATE228533T1 (en)
AU (1) AU687451B2 (en)
CA (1) CA2175670C (en)
CZ (1) CZ290186B6 (en)
DE (2) DE4337573C1 (en)
ES (1) ES2182846T3 (en)
FI (1) FI116569B (en)
HU (1) HU222087B1 (en)
IL (1) IL111263A (en)
MY (1) MY113294A (en)
NO (1) NO317112B1 (en)
PL (1) PL181725B1 (en)
RU (1) RU2148411C1 (en)
SK (1) SK284215B6 (en)
UA (1) UA43855C2 (en)
WO (1) WO1995012609A1 (en)
ZA (1) ZA948667B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0885394B1 (en) * 1996-03-08 2000-08-16 Octapharma AG Process for testing suitability of protein fractions containing factor viii
DE19618851C1 (en) * 1996-05-10 1997-07-24 Octapharma Ag Testing factor VIII containing preparations
ES2137878B1 (en) * 1997-12-01 2000-10-01 Grifols Grupo Sa PROCEDURE FOR OBTAINING AN ATTENUATED HUMAN PLASMA OF VIRUSES FOR THERAPEUTIC USE.
RU2253475C1 (en) * 2004-02-02 2005-06-10 Общество с ограниченной ответственностью "Гемоцентр" Method of preparing factor viii preparation
RU2324495C1 (en) * 2006-08-31 2008-05-20 Федеральное государственное унитарное предприятие "Научно-производственное объединение по медицинским иммунобиологическим препаратам "Микроген" Министерства здравоохранения Российской Федерации Method of making preparation of human blood coagulaton factor viii
EP2300497B1 (en) * 2008-06-24 2012-08-08 Octapharma AG A process of purifying coagulation factor viii
US9488625B2 (en) 2010-12-15 2016-11-08 Baxalta GmbH Purification of factor VIII using a conductivity gradient

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4540573A (en) * 1983-07-14 1985-09-10 New York Blood Center, Inc. Undenatured virus-free biologically active protein derivatives
DE3432083A1 (en) * 1984-08-31 1986-03-06 Behringwerke Ag, 3550 Marburg PASTEURIZED, ISOAGGLUTININ-FREE FACTOR VIII PREPARATION AND METHOD FOR THE PRODUCTION THEREOF
US5043428A (en) * 1984-08-31 1991-08-27 Behringwerke Aktiengesellschaft Pasteurized, isoagglutinin-free factor VIII preparation and a process for its production
JPS62191042A (en) * 1986-02-17 1987-08-21 Kanegafuchi Chem Ind Co Ltd Blood coagulation factor viii adsorbent and method for purifying blood coagulation factor viii using same
CA1339946C (en) * 1987-03-31 1998-07-07 Michael J. Griffith Ultrapurification process for polypeptides
US4774323A (en) * 1987-06-29 1988-09-27 Rorer Pharmaceutical Corporation Purification of von Willebrand Factor solutions using gel permeation chromatography
US4795806A (en) * 1987-07-16 1989-01-03 Miles Laboratories, Inc. Phospholipid affinity purification of Factor VIII:C
CA2001720C (en) * 1988-10-31 2001-10-02 Randal A. Goffe Membrane affinity apparatus and purification methods related thereto
ES2053684T3 (en) * 1988-11-05 1994-08-01 Octapharma Ag PROCEDURE TO PREPARE A HIGHLY PURE, NON-INFECTIOUS ANTIHEMOPHILIC FACTOR THROUGH CHROMATOGRAPHY.
CH678155A5 (en) * 1989-08-09 1991-08-15 Fischer Ag Georg
AT399818B (en) * 1992-04-24 1995-07-25 Immuno Ag METHOD FOR PRODUCING A HIGH PURIFIED VIRUS-SAFE FACTOR VIII PREPARATION

Also Published As

Publication number Publication date
PL181725B1 (en) 2001-09-28
SK56696A3 (en) 1996-10-02
HU222087B1 (en) 2003-04-28
NO961816D0 (en) 1996-05-03
FI116569B (en) 2005-12-30
NO961816L (en) 1996-05-03
CN1134157A (en) 1996-10-23
CN1109045C (en) 2003-05-21
IL111263A (en) 2000-07-16
PL314185A1 (en) 1996-09-02
MY113294A (en) 2002-01-31
HU9601192D0 (en) 1996-06-28
SK284215B6 (en) 2004-11-03
UA43855C2 (en) 2002-01-15
NO317112B1 (en) 2004-08-16
AU687451B2 (en) 1998-02-26
AU7810994A (en) 1995-05-23
KR960705841A (en) 1996-11-08
DE59410213D1 (en) 2003-01-09
EP0726907A1 (en) 1996-08-21
WO1995012609A1 (en) 1995-05-11
CZ118796A3 (en) 1996-12-11
EP0726907B1 (en) 2002-11-27
CA2175670A1 (en) 1995-05-11
FI961900A0 (en) 1996-05-03
IL111263A0 (en) 1994-12-29
CZ290186B6 (en) 2002-06-12
ZA948667B (en) 1995-07-07
HUT76530A (en) 1997-09-29
JP3739788B2 (en) 2006-01-25
DE4337573C1 (en) 1995-05-18
JPH09504532A (en) 1997-05-06
ES2182846T3 (en) 2003-03-16
RU2148411C1 (en) 2000-05-10
ATE228533T1 (en) 2002-12-15
CA2175670C (en) 2005-08-02

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