FI93351C - Menetelmä terapeuttisesti käyttökelpoisten polyetyleeniglykolikarbaminaattien valmistamiseksi - Google Patents

Menetelmä terapeuttisesti käyttökelpoisten polyetyleeniglykolikarbaminaattien valmistamiseksi

Info

Publication number: FI93351C
Authority: FI; Finland
Prior art keywords: formula; carbaminates; preparation; polyethylene glycol; therapeutically useful
Prior art date: 1987-07-23

Application number

FI883470A

Other languages

English (en)

Swedish (sv)

Other versions

FI883470A7 (fi

FI883470A0 (fi

FI93351B (fi

Inventor

Heinrich Peter

Theophile Moerker

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-07-23

Filing date

1988-07-22

Publication date

1995-03-27

1988-07-22 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1988-07-22 Publication of FI883470A0 publication Critical patent/FI883470A0/fi

1989-01-24 Publication of FI883470A7 publication Critical patent/FI883470A7/fi

1994-12-15 Publication of FI93351B publication Critical patent/FI93351B/fi

1995-03-27 Application granted granted Critical

1995-03-27 Publication of FI93351C publication Critical patent/FI93351C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/08—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/337—Polymers modified by chemical after-treatment with organic compounds containing other elements
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Polymers & Plastics (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Hospice & Palliative Care (AREA)
Diabetes (AREA)
Hematology (AREA)
Toxicology (AREA)
Psychiatry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Medicinal Preparation (AREA)
Compositions Of Macromolecular Compounds (AREA)
Phenolic Resins Or Amino Resins (AREA)

FI883470A 1987-07-23 1988-07-22 Menetelmä terapeuttisesti käyttökelpoisten polyetyleeniglykolikarbaminaattien valmistamiseksi FI93351C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CH279487		1987-07-23
CH279487		1987-07-23

Publications (4)

Publication Number	Publication Date
FI883470A0 FI883470A0 (fi)	1988-07-22
FI883470A7 FI883470A7 (fi)	1989-01-24
FI93351B FI93351B (fi)	1994-12-15
FI93351C true FI93351C (fi)	1995-03-27

Family

ID=4241735

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI883470A FI93351C (fi)	1987-07-23	1988-07-22	Menetelmä terapeuttisesti käyttökelpoisten polyetyleeniglykolikarbaminaattien valmistamiseksi

Country Status (21)

Country	Link
US (3)	US5185368A (fi)
EP (1)	EP0300969B1 (fi)
JP (1)	JPH0813795B2 (fi)
KR (1)	KR890002250A (fi)
AT (1)	ATE117328T1 (fi)
AU (1)	AU617677B2 (fi)
DD (1)	DD281810A5 (fi)
DE (1)	DE3852793D1 (fi)
DK (1)	DK410988A (fi)
ES (1)	ES2066794T3 (fi)
FI (1)	FI93351C (fi)
HU (1)	HU201517B (fi)
IE (1)	IE65550B1 (fi)
IL (1)	IL87184A (fi)
MX (1)	MX12394A (fi)
NO (1)	NO171684C (fi)
NZ (1)	NZ225506A (fi)
PH (1)	PH26779A (fi)
PT (1)	PT88060B (fi)
YU (1)	YU142188A (fi)
ZA (1)	ZA885336B (fi)

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DE3875296D1 (de) *	1987-07-23	1992-11-19	Ciba Geigy Ag	Verfahren zur selektiven n-acylierung von amino-hydroxamsaeurederivaten und darin verwendete ausgangsstoffe.
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US5578323A (en)	1992-06-15	1996-11-26	Emisphere Technologies, Inc.	Proteinoid carriers and methods for preparation and use thereof
US5310539A (en) *	1991-04-15	1994-05-10	Board Of Regents, The University Of Texas System	Melanin-based agents for image enhancement
US5254724A (en) *	1991-10-30	1993-10-19	University Of Florida Research Foundation, Inc.	Method for synthesis of desferrioxamine B, analogs and homologs thereof
GB9211779D0 (en) *	1992-06-03	1992-07-15	Ciba Geigy Ag	Amine salts
US5792451A (en)	1994-03-02	1998-08-11	Emisphere Technologies, Inc.	Oral drug delivery compositions and methods
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US6461643B2 (en) *	1993-04-22	2002-10-08	Emisphere Technologies, Inc.	Oral drug delivery compositions and methods
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IL106064A (en) *	1993-06-18	1997-11-20	Yissum Res Dev Co	Gallium complexes for the treatment of free radical-induced diseases
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BR9604880A (pt)	1995-03-31	1998-05-19	Emisphere Tech Inc	Composto composição forma de unidade de dosagem métodos para administração de um agente biologicamente ativo para preparar uma composição para administração de um agente ativo e para preparar um composto e composição farmacológica
US5965121A (en)	1995-03-31	1999-10-12	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5989539A (en)	1995-03-31	1999-11-23	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US6090958A (en)	1995-03-31	2000-07-18	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US6001347A (en)	1995-03-31	1999-12-14	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
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US5866536A (en)	1995-03-31	1999-02-02	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5820881A (en)	1995-04-28	1998-10-13	Emisphere Technologies, Inc.	Microspheres of diamide-dicarboxylic acids
US5667806A (en)	1995-06-07	1997-09-16	Emisphere Technologies, Inc.	Spray drying method and apparatus
US6051258A (en)	1995-06-07	2000-04-18	Emisphere Technologies, Inc.	Proteinoid emulsions and methods for preparation and use thereof
US5750147A (en) *	1995-06-07	1998-05-12	Emisphere Technologies, Inc.	Method of solubilizing and encapsulating itraconazole
US5824345A (en)	1995-06-07	1998-10-20	Emisphere Technologies, Inc.	Fragrances and flavorants
AU7072596A (en)	1995-09-11	1997-04-01	Emisphere Technologies, Inc.	Method for preparing omega-aminoalkanoic acid derivatives from cycloalkanones
AU2595697A (en)	1996-03-29	1997-10-22	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US7026116B1 (en) *	1996-04-04	2006-04-11	Bio-Rad Laboratories, Inc.	Polymorphisms in the region of the human hemochromatosis gene
US6140305A (en) *	1996-04-04	2000-10-31	Bio-Rad Laboratories, Inc.	Hereditary hemochromatosis gene products
US6849399B1 (en)	1996-05-23	2005-02-01	Bio-Rad Laboratories, Inc.	Methods and compositions for diagnosis and treatment of iron misregulation diseases
AU3828597A (en)	1996-06-14	1998-01-07	Emisphere Technologies, Inc.	Microencapsulated fragrances and method for preparation
US6313088B1 (en)	1997-02-07	2001-11-06	Emisphere Technologies, Inc.	8-[(2-hydroxy-4-methoxy benzoyl) amino]-octanoic acid compositions for delivering active agents
US6358504B1 (en)	1997-02-07	2002-03-19	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5990166A (en)	1997-02-07	1999-11-23	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5939381A (en)	1997-02-07	1999-08-17	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5879681A (en)	1997-02-07	1999-03-09	Emisphere Technolgies Inc.	Compounds and compositions for delivering active agents
US6060513A (en)	1997-02-07	2000-05-09	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5804688A (en)	1997-02-07	1998-09-08	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5876710A (en)	1997-02-07	1999-03-02	Emisphere Technologies Inc.	Compounds and compositions for delivering active agents
US5863944A (en)	1997-04-30	1999-01-26	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5962710A (en)	1997-05-09	1999-10-05	Emisphere Technologies, Inc.	Method of preparing salicyloylamino acids
ATE335759T1 (de)	1997-06-13	2006-09-15	Bio Rad Laboratories	Verfahren und zusammensetzungen für die diagnose und die behandlung von krankheiten, die mit eisenüberschuss oder eisenmangel assoziiert sind.
IL143962A0 (en) *	1999-01-08	2002-04-21	Emisphere Tech Inc	Polymeric delivery agents and delivery agent compounds
US6767741B1 (en) *	1999-08-27	2004-07-27	Invitrogen Corporation	Metal binding compounds and their use in cell culture medium compositions
US6648864B2 (en) *	2000-12-12	2003-11-18	The Procter & Gamble Company	Array of disposable absorbent article configurations and merchandise display system for identifying disposable absorbent article configurations for wearers
EP1419191B1 (en)	2001-08-22	2007-10-17	Bioartificial Gel Technologies Inc.	Process for the preparation of activated polyethylene glycols
US7351787B2 (en) *	2004-03-05	2008-04-01	Bioartificial Gel Technologies, Inc.	Process for the preparation of activated polyethylene glycols
US8454934B2 (en)	2006-05-25	2013-06-04	Canadian Blood Services	High molecular weight chelation structure
DE102007008655A1 (de) *	2007-02-20	2008-08-21	Henkel Ag & Co. Kgaa	Siderophor-Metall-Komplexe als Bleichkatalysatoren
RU2354390C2 (ru) *	2007-05-15	2009-05-10	ГУ Научно-исследовательский институт фармакологии Томского научного центра Сибирского отделения Российской академии медицинских наук ГУ НИИ фармакологии ТНЦ СО РАМН	Осмотический диуретик, обладающий антитоксическим действием при отравлении алифатическими спиртами
JP5763617B2 (ja) *	2009-03-26	2015-08-12	ウォーソー・オーソペディック・インコーポレーテッド	標的化薬物送達用組成物のための潜在的成分を特定する方法
KR20180105701A (ko) *	2016-02-11	2018-09-28	모데차이 체비온	신경변성의 치료를 위한 방법 및 약학 조성물
CN115109045A (zh) *	2022-07-14	2022-09-27	大连大学	一种生物基杂环单体及其均聚酯的制备方法

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DK107752C (da) *	1960-10-11	1967-07-03	Ciba Geigy	Fremgangsmåde til fremstilling af trihydroxamsyrer eller salt eller metalkomplekser deraf.
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JPH07110815B2 (ja) *	1985-11-18	1995-11-29	ボ−ド・オブ・リ−ジェンツ、ザ・ユニバ−シティ−・オブ・テキサス・システム	画像及びスペクトル向上（およびスペクトルシフト）のためのポリキレ−ト剤
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MX12394A (es) *	1987-07-23	1993-12-01	Ciba Geigy Ag	Procedimiento par la obtencion de carbamatos de polietilenglicol.
DE3875296D1 (de) *	1987-07-23	1992-11-19	Ciba Geigy Ag	Verfahren zur selektiven n-acylierung von amino-hydroxamsaeurederivaten und darin verwendete ausgangsstoffe.
ATE98631T1 (de) *	1988-01-20	1994-01-15	Ciba Geigy Ag	Verfahren zur herstellung von komplexverbindungen.
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US4999445A (en) *	1988-06-10	1991-03-12	The Regents Of The University Of California	Contrast agents for magnetic resonance imaging of the small intestine and hepatobiliary system
IL91047A (en) *	1989-07-19	1993-06-10	Yissum Res Dev Co	Zinc complexes for the treatment of free radical- induced diseases

1988
- 1988-06-22 MX MX1239488A patent/MX12394A/es unknown
- 1988-07-15 ES ES88810484T patent/ES2066794T3/es not_active Expired - Lifetime
- 1988-07-15 AT AT88810484T patent/ATE117328T1/de not_active IP Right Cessation
- 1988-07-15 EP EP88810484A patent/EP0300969B1/de not_active Expired - Lifetime
- 1988-07-15 DE DE3852793T patent/DE3852793D1/de not_active Expired - Fee Related
- 1988-07-20 US US07/221,860 patent/US5185368A/en not_active Expired - Fee Related
- 1988-07-21 PT PT88060A patent/PT88060B/pt not_active IP Right Cessation
- 1988-07-21 DD DD88318188A patent/DD281810A5/de not_active IP Right Cessation
- 1988-07-21 NZ NZ225506A patent/NZ225506A/en unknown
- 1988-07-21 YU YU01421/88A patent/YU142188A/xx unknown
- 1988-07-21 IL IL87184A patent/IL87184A/xx not_active IP Right Cessation
- 1988-07-21 NO NO883246A patent/NO171684C/no unknown
- 1988-07-22 IE IE224988A patent/IE65550B1/en not_active IP Right Cessation
- 1988-07-22 JP JP63181976A patent/JPH0813795B2/ja not_active Expired - Lifetime
- 1988-07-22 DK DK410988A patent/DK410988A/da not_active Application Discontinuation
- 1988-07-22 PH PH37261A patent/PH26779A/en unknown
- 1988-07-22 AU AU19290/88A patent/AU617677B2/en not_active Ceased
- 1988-07-22 KR KR1019880009192A patent/KR890002250A/ko not_active Abandoned
- 1988-07-22 FI FI883470A patent/FI93351C/fi not_active IP Right Cessation
- 1988-07-22 HU HU883885A patent/HU201517B/hu not_active IP Right Cessation
- 1988-07-22 ZA ZA885336A patent/ZA885336B/xx unknown
1992
- 1992-10-27 US US07/967,097 patent/US5328992A/en not_active Expired - Fee Related
1994
- 1994-04-08 US US08/224,926 patent/US5424057A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
IE65550B1 (en)	1995-11-01
AU617677B2 (en)	1991-12-05
PH26779A (en)	1992-10-13
FI883470A7 (fi)	1989-01-24
IL87184A (en)	1993-04-04
JPH0813795B2 (ja)	1996-02-14
US5185368A (en)	1993-02-09
IL87184A0 (en)	1988-12-30
YU142188A (en)	1990-04-30
DE3852793D1 (de)	1995-03-02
DK410988D0 (da)	1988-07-22
NO171684C (no)	1993-04-21
NO883246L (no)	1989-01-24
ATE117328T1 (de)	1995-02-15
KR890002250A (ko)	1989-04-10
ZA885336B (en)	1989-03-29
PT88060B (pt)	1995-03-01
NO171684B (no)	1993-01-11
HUT47529A (en)	1989-03-28
NO883246D0 (no)	1988-07-21
FI883470A0 (fi)	1988-07-22
FI93351B (fi)	1994-12-15
NZ225506A (en)	1990-12-21
ES2066794T3 (es)	1995-03-16
EP0300969A2 (de)	1989-01-25
JPS6447749A (en)	1989-02-22
AU1929088A (en)	1989-01-27
EP0300969A3 (en)	1990-12-19
US5424057A (en)	1995-06-13
EP0300969B1 (de)	1995-01-18
US5328992A (en)	1994-07-12
DK410988A (da)	1989-01-24
PT88060A (pt)	1989-06-30
MX12394A (es)	1993-12-01
IE882249L (en)	1989-01-23
HU201517B (en)	1990-11-28
DD281810A5 (de)	1990-08-22

Publication	Publication Date	Title
FI93351C (fi)	1995-03-27	Menetelmä terapeuttisesti käyttökelpoisten polyetyleeniglykolikarbaminaattien valmistamiseksi
PH20468A (en)	1987-01-14	Novel pharmaceutically active di-esters of 3,5-dicarboxy-4-substituted-pyridines and pyrans
NO173867C (no)	1994-02-16	Analogifremgangsmaate for fremstilling av terapeutisk aktive benzamider
DE3677841D1 (de)	1991-04-11	Diaminoandrostanderivate.
SE8302694D0 (sv)	1983-05-10	Immunomodulating agent
DK0479546T3 (da)	1996-11-25	Piperazinderivater
DE3372364D1 (en)	1987-08-13	1-carboxyalkanoylperhydroindole-2-carboxylic acids and derivatives
DK288686A (da)	1986-06-19	Farmaceutiske praeparater
ATE34394T1 (de)	1988-06-15	Therapeutisch aktive di-, tri-, tetra- und penta- aza-indene.
FI830397L (fi)	1983-08-06	Foerfarande foer framstaellning av imidazolidinderivat
ATE9347T1 (de)	1984-09-15	Salze von endo-8-methyl-8-syn-alkyl-8-
GR78890B (fi)	1984-10-02
IL90559A0 (en)	1990-01-18	Analgetic derivatives of phenothiazine
ES445944A1 (es)	1977-05-16	Procedimiento de preparacion de derivados de 8-amino-teofi- lina.
ES8606320A1 (es)	1986-04-16	Procedimiento de obtencion de esteres del acido ascorbico
ES8303372A1 (es)	1983-02-01	Procedimiento para la fabricacion de un compuesto de fenil-5-alquiltiazolidina-4-ona, 2-substituida
GR3005598T3 (fi)	1993-06-07
ATE40677T1 (de)	1989-02-15	Diaminderivate.
ES469955A1 (es)	1979-09-16	Un procedimiento para la preparacion de derivados de 2-naf- tilamina

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Date	Code	Title	Description
1994-11-16	BB	Publication of examined application
1997-08-26	PC	Transfer of assignment of patent	Owner name: NOVARTIS AG
1998-07-22	MM	Patent lapsed
2004-08-31	MM	Patent lapsed	Owner name: NOVARTIS AG