ES8303372A1 - Procedimiento para la fabricacion de un compuesto de fenil-5-alquiltiazolidina-4-ona, 2-substituida - Google Patents
Procedimiento para la fabricacion de un compuesto de fenil-5-alquiltiazolidina-4-ona, 2-substituidaInfo
- Publication number
- ES8303372A1 ES8303372A1 ES506702A ES506702A ES8303372A1 ES 8303372 A1 ES8303372 A1 ES 8303372A1 ES 506702 A ES506702 A ES 506702A ES 506702 A ES506702 A ES 506702A ES 8303372 A1 ES8303372 A1 ES 8303372A1
- Authority
- ES
- Spain
- Prior art keywords
- ones
- phenyl
- substituted
- alkylthiazolidin
- peptic ulcer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 208000008469 Peptic Ulcer Diseases 0.000 title abstract 3
- 208000011906 peptic ulcer disease Diseases 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/14—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE COMPUESTOS DE FENIL-5-ALQUITIAZOLIDINA-4-ONA, 2-SUBSTITUIDA, DE FORMULA DESARROLLADA (I), EN LA QUE R Y R SIGNIFICAN RESPECTIVAMENTE UN GRUPO ALQUILO INFERIOR DE UNO A TRES ATOMOS DE CARBONO, Y N REPRESENTA 1, 2 O 3. CONSISTE EN HACER REACCIONAR UN ALDEHIDO REPRESENTADO POR LA FORMULA (II), EN LA QUE R Y N TIENEN LOS SIGNIFICADOS YA INDICADOS, CON EL ACIDO 2-MERCAPTOPROPIONICO O CON UN ESTER DEL MISMO, EN PRESENCIA DE UN DISOLVENTE INERTE QUE CONTIENE UN COMPUESTO AMONICO, TAL COMO CARBONATO AMONICO. LA REACCION SE LLEVA A EFECTO A UNA TEMPERATURA COMPRENDIDA ENTRE 50 Y 150 GRADOS. DE APLICACION EN LA PREPARACION DE MEDICAMENTOS ANTI-ULCERA PEPTICA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP55141239A JPS6052747B2 (ja) | 1980-10-09 | 1980-10-09 | ２−置換フエニル−５−アルキルチアゾリジン−４−オン、及び該化合物有効成分とする抗消化性潰瘍剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES506702A0 ES506702A0 (es) | 1983-02-01 |
| ES8303372A1 true ES8303372A1 (es) | 1983-02-01 |
Family
ID=15287329
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES506702A Expired ES8303372A1 (es) | 1980-10-09 | 1981-10-09 | Procedimiento para la fabricacion de un compuesto de fenil-5-alquiltiazolidina-4-ona, 2-substituida |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4434172A (es) |
| EP (1) | EP0050002B1 (es) |
| JP (1) | JPS6052747B2 (es) |
| KR (1) | KR860000059B1 (es) |
| CA (1) | CA1167448A (es) |
| DE (1) | DE3171323D1 (es) |
| ES (1) | ES8303372A1 (es) |
| HU (1) | HU182756B (es) |
| MX (2) | MX7117E (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1154447A (en) * | 1979-07-09 | 1983-09-27 | Takao Kawasaki | 2-substituted-4-thiazolidones |
| DE3670292D1 (de) * | 1985-06-25 | 1990-05-17 | Ishihara Sangyo Kaisha | Organophosphorverbindungen, verfahren zu ihrer herstellung und sie enthaltende insektizide, mitizide, nematozide oder bodenpestizide praeparate. |
| US5021435A (en) * | 1988-01-22 | 1991-06-04 | Sumitomo Pharmaceuticals Company, Limited | Certain pyridyl-thiazolidin-4-one having anti-ulcer activity |
| JPH0479620A (ja) * | 1990-07-20 | 1992-03-13 | Matsushita Electric Ind Co Ltd | コードレス電話装置 |
| JPH0553058U (ja) * | 1991-12-24 | 1993-07-13 | 株式会社フジクラ | 絶縁ケーブル |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2623048A (en) | 1948-04-05 | 1952-12-23 | Parke Davis & Co | 4-thiazolidone derivatives and process for preparing the same |
| US3270027A (en) | 1963-10-15 | 1966-08-30 | Sterling Drug Inc | 2-trichloromethyl-4-thiazolidones |
| GB1345159A (en) | 1970-06-26 | 1974-01-30 | Ici Ltd | Oxathiolanone and thiazolidinone derivatives |
| GB1428390A (en) | 1972-08-18 | 1976-03-17 | Ici Ltd | Thiazolidinones |
| US4053471A (en) | 1976-11-11 | 1977-10-11 | E. R. Squibb & Sons, Inc. | 4-thiazolidinone derivatives |
| CA1154447A (en) | 1979-07-09 | 1983-09-27 | Takao Kawasaki | 2-substituted-4-thiazolidones |
-
1980
- 1980-10-09 JP JP55141239A patent/JPS6052747B2/ja not_active Expired
-
1981
- 1981-09-25 US US06/305,834 patent/US4434172A/en not_active Expired - Lifetime
- 1981-10-02 CA CA000387166A patent/CA1167448A/en not_active Expired
- 1981-10-07 DE DE8181304653T patent/DE3171323D1/de not_active Expired
- 1981-10-07 EP EP81304653A patent/EP0050002B1/en not_active Expired
- 1981-10-08 HU HU812911A patent/HU182756B/hu not_active IP Right Cessation
- 1981-10-08 KR KR1019810003807A patent/KR860000059B1/ko not_active Expired
- 1981-10-09 MX MX819706U patent/MX7117E/es unknown
- 1981-10-09 ES ES506702A patent/ES8303372A1/es not_active Expired
-
1985
- 1985-10-14 MX MX901585A patent/MX9015A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA1167448A (en) | 1984-05-15 |
| EP0050002A1 (en) | 1982-04-21 |
| KR860000059B1 (ko) | 1986-02-06 |
| MX9015A (es) | 1993-12-01 |
| US4434172A (en) | 1984-02-28 |
| MX7117E (es) | 1987-06-29 |
| HU182756B (en) | 1984-03-28 |
| JPS5764683A (en) | 1982-04-19 |
| DE3171323D1 (en) | 1985-08-14 |
| EP0050002B1 (en) | 1985-07-10 |
| ES506702A0 (es) | 1983-02-01 |
| JPS6052747B2 (ja) | 1985-11-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19960603 |