FI90772B - Förfarande för framställning av antiarytmiska imidazoler - Google Patents

Förfarande för framställning av antiarytmiska imidazoler Download PDF

Info

Publication number: FI90772B
Authority: FI; Finland
Prior art keywords: formula; substituent; compound; piperidinyl; choh
Prior art date: 1988-09-23

Application number

FI894392A

Other languages

English (en)

Finnish (fi)

Other versions

FI894392A7 (sv

FI90772C (sv

FI894392A0 (sv

Inventor

Albert A Carr

Richard C Dage

John E Koerner

Tung Li

David A Hay

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-09-23

Filing date

1989-09-18

Publication date

1993-12-15

1989-09-18 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1989-09-18 Publication of FI894392A0 publication Critical patent/FI894392A0/sv

1990-03-24 Publication of FI894392A7 publication Critical patent/FI894392A7/sv

1993-12-15 Application granted granted Critical

1993-12-15 Publication of FI90772B publication Critical patent/FI90772B/sv

1994-03-25 Publication of FI90772C publication Critical patent/FI90772C/sv

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Heart & Thoracic Surgery (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

FI894392A 1988-09-23 1989-09-18 Förfarande för framställning av antiarytmiska imidazoler FI90772C (sv)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US24876888		1988-09-23
US07/248,768 US4868194A (en)	1988-09-23	1988-09-23	Imidazole antiarrhythmics

Publications (4)

Publication Number	Publication Date
FI894392A0 FI894392A0 (sv)	1989-09-18
FI894392A7 FI894392A7 (sv)	1990-03-24
FI90772B true FI90772B (sv)	1993-12-15
FI90772C FI90772C (sv)	1994-03-25

Family

ID=22940601

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI894392A FI90772C (sv)	1988-09-23	1989-09-18	Förfarande för framställning av antiarytmiska imidazoler

Country Status (21)

Country	Link
US (1)	US4868194A (sv)
EP (1)	EP0360275B1 (sv)
JP (1)	JP2852536B2 (sv)
KR (1)	KR0130646B1 (sv)
CN (1)	CN1023702C (sv)
AR (1)	AR246964A1 (sv)
AT (1)	ATE100094T1 (sv)
AU (1)	AU620643B2 (sv)
CA (1)	CA1335594C (sv)
DE (1)	DE68912252T2 (sv)
DK (1)	DK469389A (sv)
ES (1)	ES2061861T3 (sv)
FI (1)	FI90772C (sv)
HU (1)	HU202860B (sv)
IE (1)	IE62556B1 (sv)
IL (1)	IL91698A0 (sv)
NO (1)	NO174466C (sv)
NZ (1)	NZ230705A (sv)
PH (1)	PH26029A (sv)
PT (1)	PT91741B (sv)
ZA (1)	ZA897109B (sv)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2969359B2 (ja) *	1989-01-13	1999-11-02	武田薬品工業株式会社	環状アミン化合物
US5189036A (en) *	1990-06-20	1993-02-23	Schering Ag	Imidazolylbenzoyl substituted heterocycles
BR0209932A (pt)	2001-05-22	2004-10-13	Neurogen Corp	Composto ou sal farmaceuticamente aceitável do mesmo, composição farmacêutica, preparação farmacêutica embalada, métodos para modular ligação de mch a um receptor de mch e de mvc, para alterar a atividade de transdução de sinal de um receptor de mch em uma célula, para tratar uma doença ou distúrbio associado com a ativação de receptor de mch patogênico obesidade e para determinar a presença ou ausência de receptor de mch em uma amostra, e, uso de um composto
WO2005110989A1 (en) *	2004-04-07	2005-11-24	Neurogen Corporation	Substituted 1-heteroaryl-4-substituted piperazine and piperidine analogues
US7253168B2 (en) *	2004-04-07	2007-08-07	Neurogen Corporation	Substituted 1-benzyl-4-substituted piperazine analogues
TW200609219A (en) *	2004-06-17	2006-03-16	Neurogen Corp	Aryl-substituted piperazine derivatives
KR20220154949A (ko)	2021-05-14	2022-11-22	삼성중공업 주식회사	파이프 밸브 탈부착 장치

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4556665A (en) *	1984-07-09	1985-12-03	Schering A.G.	Cardiotonic 1,3-dihydro-4-[[(imidazol-1-yl)aryl]carbonyl]imidazol-2-ones
PH23283A (en) *	1986-02-26	1989-06-30	Eisai Co Ltd	Piperidine derivative, pharmaceutical composition containing the same and method of use thereof
US4791121A (en) *	1987-11-02	1988-12-13	The Boc Group, Inc.	4-phenyl-4-(N-(phenyl)amido) piperidine derivatives and pharmaceutical compositions and method employing such compounds

1988
- 1988-09-23 US US07/248,768 patent/US4868194A/en not_active Expired - Lifetime
1989
- 1989-09-18 PT PT91741A patent/PT91741B/pt not_active IP Right Cessation
- 1989-09-18 AU AU41526/89A patent/AU620643B2/en not_active Ceased
- 1989-09-18 AR AR89314948A patent/AR246964A1/es active
- 1989-09-18 FI FI894392A patent/FI90772C/sv not_active IP Right Cessation
- 1989-09-18 ZA ZA897109A patent/ZA897109B/xx unknown
- 1989-09-19 NZ NZ230705A patent/NZ230705A/en unknown
- 1989-09-19 CA CA000612009A patent/CA1335594C/en not_active Expired - Fee Related
- 1989-09-20 IL IL91698A patent/IL91698A0/xx not_active IP Right Cessation
- 1989-09-21 KR KR1019890013563A patent/KR0130646B1/ko not_active Expired - Fee Related
- 1989-09-21 JP JP1243564A patent/JP2852536B2/ja not_active Expired - Fee Related
- 1989-09-22 DE DE68912252T patent/DE68912252T2/de not_active Expired - Fee Related
- 1989-09-22 EP EP89117514A patent/EP0360275B1/en not_active Expired - Lifetime
- 1989-09-22 AT AT89117514T patent/ATE100094T1/de not_active IP Right Cessation
- 1989-09-22 IE IE304989A patent/IE62556B1/en not_active IP Right Cessation
- 1989-09-22 ES ES89117514T patent/ES2061861T3/es not_active Expired - Lifetime
- 1989-09-22 CN CN89107424A patent/CN1023702C/zh not_active Expired - Fee Related
- 1989-09-22 DK DK469389A patent/DK469389A/da not_active Application Discontinuation
- 1989-09-22 PH PH39277A patent/PH26029A/en unknown
- 1989-09-22 NO NO893784A patent/NO174466C/no not_active IP Right Cessation
- 1989-09-22 HU HU894983A patent/HU202860B/hu not_active IP Right Cessation

Also Published As

Publication number	Publication date
NO174466C (no)	1994-05-11
PT91741A (pt)	1990-03-30
IL91698A0 (en)	1990-06-10
AU4152689A (en)	1990-03-29
ZA897109B (en)	1990-06-27
PH26029A (en)	1992-01-29
AU620643B2 (en)	1992-02-20
IE62556B1 (en)	1995-02-08
NO174466B (no)	1994-01-31
AR246964A1 (es)	1994-10-31
CN1023702C (zh)	1994-02-09
NO893784D0 (no)	1989-09-22
NZ230705A (en)	1991-03-26
JPH02124885A (ja)	1990-05-14
FI894392A7 (sv)	1990-03-24
US4868194A (en)	1989-09-19
FI90772C (sv)	1994-03-25
HUT50811A (en)	1990-03-28
DE68912252D1 (de)	1994-02-24
CA1335594C (en)	1995-05-16
KR900004717A (ko)	1990-04-12
EP0360275A2 (en)	1990-03-28
HU202860B (en)	1991-04-29
DK469389D0 (da)	1989-09-22
FI894392A0 (sv)	1989-09-18
DK469389A (da)	1990-03-24
EP0360275B1 (en)	1994-01-12
IE893049L (en)	1990-03-23
NO893784L (no)	1990-03-26
KR0130646B1 (ko)	1998-04-10
PT91741B (pt)	1995-05-31
DE68912252T2 (de)	1994-07-07
ES2061861T3 (es)	1994-12-16
CN1041363A (zh)	1990-04-18
EP0360275A3 (en)	1990-08-22
JP2852536B2 (ja)	1999-02-03
ATE100094T1 (de)	1994-01-15

Publication	Publication Date	Title
US5229400A (en)	1993-07-20	Piperidine compounds and their use as antiarrhythmic agents
CA1322007C (en)	1993-09-07	1,4-disubstituted piperidinyl compounds, pharmaceutical compositions thereof, and their methods of preparation
HUT58275A (en)	1992-02-28	Process for producing amines and pharmaceutical compositions containing them
FI90772B (sv)	1993-12-15	Förfarande för framställning av antiarytmiska imidazoler
US5166211A (en)	1992-11-24	Method of using 1,4-disubstituted piperidinyl compounds in the treatment of coronary vasospasons and variant angina
US5028616A (en)	1991-07-02	N-benzylpiperidine amides
EP0532629B1 (en)	1996-11-06	1-piperidinyl alkanoylarylsulfonamide derivatives
AU601946B2 (en)	1990-09-27	1,4-dihydropyridine derivatives useful for the treatment of cardiovascular disorders
US5478846A (en)	1995-12-26	1-piperidinyl alkanoylanyl sulfonamides for treatment of cardiac arrhythmia
CA1282411C (en)	1991-04-02	1,4,5,6,7,8-hexahydroquinoline compounds
US5541201A (en)	1996-07-30	Antiarrhythmic piperidin-1-yl-2,2-dialkylpropanone arylsulfonamide derivatives
JPS5976083A (ja)	1984-04-28	ジヒドロピリジン類
AU2002316531B2 (en)	2007-09-13	Substituted anilinic piperidines as MCH selective antagonists
EP0295769A2 (en)	1988-12-21	1,4 Dihydropyridine derivatives, process for their preparation and their uses in pharmaceutical compositions

Legal Events

Date	Code	Title	Description
1993-11-16	BB	Publication of examined application
2004-08-31	MM	Patent lapsed	Owner name: MERRELL DOW PHARMACEUTICALS INC.