FI864377L - 5-aryl-2,4-dialkyl-3h-1,2,4 -triazol-3-tioner och deras anvaendning som antidepressanter. - Google Patents

5-aryl-2,4-dialkyl-3h-1,2,4 -triazol-3-tioner och deras anvaendning som antidepressanter. Download PDF

Info

Publication number: FI864377L
Authority: FI; Finland
Prior art keywords: antidepressanter; tioner; triazol; dialkyl; aryl
Prior art date: 1985-10-29

Application number

FI864377A

Other languages

English (en)

Other versions

FI89047C (fi

FI89047B (fi

FI864377A0 (fi

Inventor

John M Kane

Francis P Miller

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-10-29

Filing date

1986-10-28

Publication date

1987-04-30

1986-10-28 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1986-10-28 Publication of FI864377A0 publication Critical patent/FI864377A0/fi

1987-04-30 Publication of FI864377L publication Critical patent/FI864377L/fi

1993-04-30 Application granted granted Critical

1993-04-30 Publication of FI89047B publication Critical patent/FI89047B/fi

1993-08-10 Publication of FI89047C publication Critical patent/FI89047C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Psychiatry (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

FI864377A 1985-10-29 1986-10-28 Foerfarande foer framstaellning av terapeutiskt anvaendbara 5-aryl-2,4-dialkyl-3h-1,2,4-triazol-3-tioner FI89047C (fi)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date
US79235985A	1985-10-29	1985-10-29
US79235985		1985-10-29
US80761385A	1985-12-11	1985-12-11
US80761385		1985-12-11

Publications (4)

Publication Number	Publication Date
FI864377A0 FI864377A0 (fi)	1986-10-28
FI864377L true FI864377L (fi)	1987-04-30
FI89047B FI89047B (fi)	1993-04-30
FI89047C FI89047C (fi)	1993-08-10

Family

ID=27121269

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI864377A FI89047C (fi)	1985-10-29	1986-10-28	Foerfarande foer framstaellning av terapeutiskt anvaendbara 5-aryl-2,4-dialkyl-3h-1,2,4-triazol-3-tioner

Country Status (19)

Country	Link
EP (1)	EP0221485B1 (fi)
JP (1)	JPH07116162B2 (fi)
KR (1)	KR900003879B1 (fi)
CN (1)	CN1014993B (fi)
AR (1)	AR243171A1 (fi)
AU (1)	AU587646B2 (fi)
CA (2)	CA1284997C (fi)
DE (1)	DE3676632D1 (fi)
DK (1)	DK164785C (fi)
ES (1)	ES2031449T3 (fi)
FI (1)	FI89047C (fi)
GR (1)	GR3001246T3 (fi)
HU (1)	HU196191B (fi)
IE (1)	IE58969B1 (fi)
IL (1)	IL80434A (fi)
NO (1)	NO165542C (fi)
NZ (1)	NZ218087A (fi)
PH (2)	PH22377A (fi)
PT (1)	PT83636B (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR243169A1 (es) *	1985-10-29	1993-07-30	Merrell Pharma Inc	Procedimiento para preparar 5-naftil-2,4-dialquil-3h-1,2,4-triazol-3-tionas.
JP2593084B2 (ja) *	1986-12-19	1997-03-19	メレルダウファーマスーティカルズインコーポレーテッド	５−アリールー３ｈ−１，２，４−トリアゾールー３−オン類の神経変性障害の処置への用途
PH24094A (en) *	1986-12-19	1990-03-05	Merrell Dow Pharma	5-aryl-3h-1,2,4-triazol-3-ones and their use as anticonvulsants
EP0280867A1 (en) *	1987-01-27	1988-09-07	Merrell Dow Pharmaceuticals Inc.	Process for the preparation of 5-aryl-2,4-dialkyl-3H-1,2,4-triazole-3-thiones
US4847276A (en) *	1988-09-06	1989-07-11	Merrell Dow Pharmaceuticals Inc.	Treatment of thromobocytosis with 5-(4-chlorophenyl)-2,4-diemthyl-3H-1,2,4-triazole-3-thione
KR100321885B1 (ko) *	1993-10-29	2002-06-24	메렐 파마슈티칼스 인크.	기억력향상제로서 유용한 3-아릴-4-알킬및4,5-디알킬-4h-1,2,4-트리아졸
WO1996001812A1 (en) *	1994-07-07	1996-01-25	Merrell Pharmaceuticals Inc.	Process for the preparation of 5-aryl-2,4-dialkyl-3h-1,2,4-triazole-3-thiones

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR243169A1 (es) *	1985-10-29	1993-07-30	Merrell Pharma Inc	Procedimiento para preparar 5-naftil-2,4-dialquil-3h-1,2,4-triazol-3-tionas.
DK570987A (da) *	1986-12-01	1988-06-02	Hoffmann La Roche	Oxadiazol-, thiadiazol- og triazolforbindelser

1986
- 1986-10-22 AR AR86305652A patent/AR243171A1/es active
- 1986-10-24 AU AU64386/86A patent/AU587646B2/en not_active Ceased
- 1986-10-24 PH PH34414A patent/PH22377A/en unknown
- 1986-10-24 CA CA000521330A patent/CA1284997C/en not_active Expired - Lifetime
- 1986-10-27 EP EP86114874A patent/EP0221485B1/en not_active Expired - Lifetime
- 1986-10-27 DE DE8686114874T patent/DE3676632D1/de not_active Expired - Fee Related
- 1986-10-27 ES ES198686114874T patent/ES2031449T3/es not_active Expired - Lifetime
- 1986-10-28 JP JP61254829A patent/JPH07116162B2/ja not_active Expired - Lifetime
- 1986-10-28 IE IE283286A patent/IE58969B1/en not_active IP Right Cessation
- 1986-10-28 FI FI864377A patent/FI89047C/fi not_active IP Right Cessation
- 1986-10-28 KR KR1019860009007A patent/KR900003879B1/ko not_active Expired
- 1986-10-28 IL IL80434A patent/IL80434A/xx not_active IP Right Cessation
- 1986-10-28 HU HU864526A patent/HU196191B/hu not_active IP Right Cessation
- 1986-10-28 PT PT83636A patent/PT83636B/pt not_active IP Right Cessation
- 1986-10-28 CN CN86106880A patent/CN1014993B/zh not_active Expired
- 1986-10-28 NO NO864306A patent/NO165542C/no not_active IP Right Cessation
- 1986-10-28 DK DK514886A patent/DK164785C/da active
- 1986-10-28 NZ NZ218087A patent/NZ218087A/xx unknown
1987
- 1987-10-08 PH PH35910A patent/PH23275A/en unknown
1990
- 1990-08-07 CA CA000615808A patent/CA1301655C/en not_active Expired - Lifetime
- 1990-12-28 GR GR90401022T patent/GR3001246T3/el unknown

Also Published As

Publication number	Publication date
PH22377A (en)	1988-08-12
PH23275A (en)	1989-06-23
CN86106880A (zh)	1987-06-10
AU6438686A (en)	1987-04-30
KR900003879B1 (ko)	1990-06-04
NO165542C (no)	1991-02-27
FI89047C (fi)	1993-08-10
DK514886D0 (da)	1986-10-28
JPH07116162B2 (ja)	1995-12-13
JPS62106085A (ja)	1987-05-16
HU196191B (en)	1988-10-28
DK514886A (da)	1987-04-30
NO165542B (no)	1990-11-19
EP0221485A1 (en)	1987-05-13
CA1284997C (en)	1991-06-18
DK164785B (da)	1992-08-17
FI89047B (fi)	1993-04-30
FI864377A0 (fi)	1986-10-28
HUT45030A (en)	1988-05-30
DE3676632D1 (de)	1991-02-07
PT83636B (pt)	1988-10-14
PT83636A (en)	1986-11-01
ES2031449T3 (es)	1992-12-16
IE58969B1 (en)	1993-12-01
IL80434A0 (en)	1987-01-30
CN1014993B (zh)	1991-12-04
EP0221485B1 (en)	1990-12-27
IE862832L (en)	1987-04-29
IL80434A (en)	1991-01-31
KR870004006A (ko)	1987-05-06
NO864306D0 (no)	1986-10-28
GR3001246T3 (en)	1992-07-30
NZ218087A (en)	1989-05-29
AU587646B2 (en)	1989-08-24
NO864306L (no)	1987-04-30
CA1301655C (en)	1992-05-26
AR243171A1 (es)	1993-07-30
DK164785C (da)	1992-12-28

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Legal Events

Date	Code	Title	Description
1993-04-01	BB	Publication of examined application
2004-08-31	MM	Patent lapsed	Owner name: MERRELL DOW PHARMACEUTICALS INC.