FI840367L - Vid framstaellning av som mellanprodukter vid terapeutiskt anvaendbara 2 -acetoximetyl-2 -metyl-(5r)-penam-3 -karboxyksyra-1,1-dioxidderivat anvaenbara 2 -acetoxymetyl-2 -metyl-(5r)-penam-3 -karboxylsyraderivat - Google Patents

Vid framstaellning av som mellanprodukter vid terapeutiskt anvaendbara 2 -acetoximetyl-2 -metyl-(5r)-penam-3 -karboxyksyra-1,1-dioxidderivat anvaenbara 2 -acetoxymetyl-2 -metyl-(5r)-penam-3 -karboxylsyraderivat Download PDF

Info

Publication number: FI840367L
Authority: FI; Finland
Prior art keywords: penam; acetoxymethyl; methyl; vid; derivatives
Prior art date: 1979-09-26

Application number

FI840367A

Other languages

English (en)

Other versions

FI67854B (fi

FI67854C (fi

FI840367A0 (fi

Inventor

Wayne Ernest Barth

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-09-26

Filing date

1984-01-30

Publication date

1984-01-30

1984-01-30 Application filed by Pfizer filed Critical Pfizer

1984-01-30 Publication of FI840367L publication Critical patent/FI840367L/fi

1984-01-30 Publication of FI840367A0 publication Critical patent/FI840367A0/fi

1985-02-28 Publication of FI67854B publication Critical patent/FI67854B/fi

1985-06-10 Application granted granted Critical

1985-06-10 Publication of FI67854C publication Critical patent/FI67854C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D499/28—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with modified 2-carboxyl group
- C07D499/32—Esters

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cephalosporin Compounds (AREA)
Saccharide Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

FI840367A 1979-09-26 1984-01-30 Som mellanprodukter vid framstaellningen av terapeutiskt anvaendbara 2beta-acetoximetyl-2alfa-metyl-(5r)-penam-3alfa-karboxylsyra-1,1-dioxidderivat anvaendbara 2beta-acetoximetyl-2alfa-metyl-(5r)-penam-3alfa-karboxylsyraderivat FI67854C (fi)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US7912779		1979-09-26
US06/079,127 US4256733A (en)	1979-09-26	1979-09-26	Acetoxymethyl penam compounds as β-lactamase inhibitors
FI803028		1980-09-25
FI803028A FI67552C (fi)	1979-09-26	1980-09-25	Foerfarande foer framstaellning av en ny som beta-laktamas-inhibitor anvaendbar 2beta-acetoxymetyl-2alfa-metyl-(5r)-penam-3alfa-karboxylsyra-1,1-dioxid

Publications (4)

Publication Number	Publication Date
FI840367L true FI840367L (fi)	1984-01-30
FI840367A0 FI840367A0 (fi)	1984-01-30
FI67854B FI67854B (fi)	1985-02-28
FI67854C FI67854C (fi)	1985-06-10

Family

ID=22148609

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
FI803028A FI67552C (fi)	1979-09-26	1980-09-25	Foerfarande foer framstaellning av en ny som beta-laktamas-inhibitor anvaendbar 2beta-acetoxymetyl-2alfa-metyl-(5r)-penam-3alfa-karboxylsyra-1,1-dioxid
FI840367A FI67854C (fi)	1979-09-26	1984-01-30	Som mellanprodukter vid framstaellningen av terapeutiskt anvaendbara 2beta-acetoximetyl-2alfa-metyl-(5r)-penam-3alfa-karboxylsyra-1,1-dioxidderivat anvaendbara 2beta-acetoximetyl-2alfa-metyl-(5r)-penam-3alfa-karboxylsyraderivat

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
FI803028A FI67552C (fi)	1979-09-26	1980-09-25	Foerfarande foer framstaellning av en ny som beta-laktamas-inhibitor anvaendbar 2beta-acetoxymetyl-2alfa-metyl-(5r)-penam-3alfa-karboxylsyra-1,1-dioxid

Country Status (36)

Country	Link
US (1)	US4256733A (fi)
JP (1)	JPS6016958B2 (fi)
KR (1)	KR840000796B1 (fi)
AR (1)	AR224547A1 (fi)
AT (1)	AT366384B (fi)
AU (1)	AU517074B2 (fi)
BE (1)	BE885389A (fi)
CA (1)	CA1150242A (fi)
CH (1)	CH645646A5 (fi)
CS (1)	CS212284B2 (fi)
DD (1)	DD153123A5 (fi)
DE (1)	DE3035995C2 (fi)
DK (1)	DK404980A (fi)
EG (1)	EG14888A (fi)
ES (1)	ES495354A0 (fi)
FI (2)	FI67552C (fi)
FR (1)	FR2465736A1 (fi)
GB (2)	GB2059420B (fi)
GR (1)	GR70065B (fi)
HU (1)	HU183212B (fi)
IE (2)	IE50507B1 (fi)
IL (1)	IL61117A (fi)
IN (1)	IN154557B (fi)
IT (1)	IT1132754B (fi)
LU (1)	LU82795A1 (fi)
MX (1)	MX6580E (fi)
NL (1)	NL185923C (fi)
NO (2)	NO160370C (fi)
NZ (1)	NZ195058A (fi)
PH (1)	PH15697A (fi)
PL (1)	PL126949B1 (fi)
PT (1)	PT71837B (fi)
SE (2)	SE449865B (fi)
SU (1)	SU959628A3 (fi)
YU (1)	YU41733B (fi)
ZA (1)	ZA805132B (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4364957A (en) *	1979-09-26	1982-12-21	Pfizer Inc.	Bis-esters of alkanediols as antibacterial agents
US4511512A (en) *	1980-05-01	1985-04-16	Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Produktionsaktiensel skab)	Substantially pure dicyclohexyl ammonium 6-β-bromo-penicillanate
US4361513A (en) *	1980-12-11	1982-11-30	Pfizer Inc.	Esters of penicillanic acid sulfone
US4474698A (en) *	1980-12-11	1984-10-02	Pfizer Inc.	Process for preparing esters of penicillanic acid sulfone
US4558042A (en) *	1981-05-06	1985-12-10	Farmitalia Carlo Erba S.P.A.	β-Lactam-containing antibacterial agents and β-lactamase inhibitors
ZA826687B (en) *	1981-09-14	1983-07-27	Pfizer	Beta-lactamase inhibiting 2-beta-substituted-2-alpha-methyl 5(r)penam-3-alpha-carboxylic acid 1,1-dioxides and intermediates therefor
JPS58185589A (ja) *	1982-04-23	1983-10-29	Taiho Yakuhin Kogyo Kk	ペニシリン誘導体
US4861768A (en) *	1986-02-27	1989-08-29	Taiho Pharmaceutical Company, Limited	2 β-substituted thiomethylpenicillin derivatives and their preparation and use
JPS62198687A (ja) *	1986-02-27	1987-09-02	Taiho Yakuhin Kogyo Kk	２β−置換チオメチルペニシリン誘導体
AU3345193A (en) *	1991-12-19	1993-07-19	Novo Nordisk A/S	An improved method for the preparation of certain beta-lactam antibiotics
CN115385934A (zh) *	2022-10-26	2022-11-25	北京纳百生物科技有限公司	一种舒巴坦半抗原及其合成方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE648188A (fi)	1963-05-29	1964-09-16
IN149747B (fi) *	1977-06-07	1982-04-03	Pfizer

1979
- 1979-09-26 US US06/079,127 patent/US4256733A/en not_active Expired - Lifetime
1980
- 1980-08-13 SE SE8005714A patent/SE449865B/sv not_active IP Right Cessation
- 1980-08-20 IN IN607/DEL/80A patent/IN154557B/en unknown
- 1980-08-20 ZA ZA00805132A patent/ZA805132B/xx unknown
- 1980-09-19 SU SU802983144A patent/SU959628A3/ru active
- 1980-09-19 HU HU802310A patent/HU183212B/hu unknown
- 1980-09-22 CS CS806403A patent/CS212284B2/cs unknown
- 1980-09-22 PL PL1980226868A patent/PL126949B1/pl unknown
- 1980-09-23 GR GR62939A patent/GR70065B/el unknown
- 1980-09-23 AT AT0474680A patent/AT366384B/de not_active IP Right Cessation
- 1980-09-23 CA CA000360886A patent/CA1150242A/en not_active Expired
- 1980-09-23 GB GB8030639A patent/GB2059420B/en not_active Expired
- 1980-09-23 EG EG584/80A patent/EG14888A/xx active
- 1980-09-23 IL IL61117A patent/IL61117A/xx unknown
- 1980-09-24 MX MX809044U patent/MX6580E/es unknown
- 1980-09-24 LU LU82795A patent/LU82795A1/fr unknown
- 1980-09-24 KR KR1019800003721A patent/KR840000796B1/ko not_active Expired
- 1980-09-24 PH PH24617A patent/PH15697A/en unknown
- 1980-09-24 AR AR282629A patent/AR224547A1/es active
- 1980-09-24 DE DE3035995A patent/DE3035995C2/de not_active Expired
- 1980-09-25 AU AU62713/80A patent/AU517074B2/en not_active Ceased
- 1980-09-25 DK DK404980A patent/DK404980A/da not_active Application Discontinuation
- 1980-09-25 FI FI803028A patent/FI67552C/fi not_active IP Right Cessation
- 1980-09-25 BE BE0/202222A patent/BE885389A/fr not_active IP Right Cessation
- 1980-09-25 NO NO802836A patent/NO160370C/no unknown
- 1980-09-25 ES ES495354A patent/ES495354A0/es active Granted
- 1980-09-25 IE IE1095/85A patent/IE50507B1/en unknown
- 1980-09-25 PT PT71837A patent/PT71837B/pt unknown
- 1980-09-25 IT IT24920/80A patent/IT1132754B/it active
- 1980-09-25 NZ NZ195058A patent/NZ195058A/xx unknown
- 1980-09-25 DD DD80224128A patent/DD153123A5/de unknown
- 1980-09-25 JP JP55133639A patent/JPS6016958B2/ja not_active Expired
- 1980-09-25 CH CH719980A patent/CH645646A5/fr not_active IP Right Cessation
- 1980-09-25 FR FR8020618A patent/FR2465736A1/fr active Granted
- 1980-09-25 IE IE1998/80A patent/IE50506B1/en not_active IP Right Cessation
- 1980-09-25 YU YU2449/80A patent/YU41733B/xx unknown
- 1980-09-25 NL NLAANVRAGE8005344,A patent/NL185923C/xx not_active IP Right Cessation
1983
- 1983-03-25 NO NO83831082A patent/NO160299C/no unknown
- 1983-07-22 GB GB08319784A patent/GB2125037B/en not_active Expired
1984
- 1984-01-30 FI FI840367A patent/FI67854C/fi not_active IP Right Cessation
1985
- 1985-02-27 SE SE8500965A patent/SE461528B/sv not_active IP Right Cessation

Also Published As

Publication number	Publication date
YU244980A (en)	1983-02-28
NL8005344A (nl)	1981-03-30
PL126949B1 (en)	1983-09-30
JPS6016958B2 (ja)	1985-04-30
AR224547A1 (es)	1981-12-15
PT71837A (en)	1980-10-01
DE3035995A1 (de)	1981-04-02
NL185923B (nl)	1990-03-16
IE801095L (en)	1981-01-09
NZ195058A (en)	1982-12-07
GB2059420A (en)	1981-04-23
PL226868A1 (fi)	1981-10-16
NO831082L (no)	1981-03-27
DK404980A (da)	1981-03-27
NL185923C (nl)	1990-08-16
DD153123A5 (de)	1981-12-23
FR2465736A1 (fr)	1981-03-27
IT1132754B (it)	1986-07-02
IN154557B (fi)	1984-11-10
AU6271380A (en)	1981-04-09
NO160299B (no)	1988-12-27
PH15697A (en)	1983-03-14
BE885389A (fr)	1981-03-25
LU82795A1 (fr)	1981-04-17
CS212284B2 (en)	1982-03-26
SE461528B (sv)	1990-02-26
NO160299C (no)	1989-04-05
FI67854B (fi)	1985-02-28
GB8319784D0 (en)	1983-08-24
HU183212B (en)	1984-04-28
FI67854C (fi)	1985-06-10
AT366384B (de)	1982-04-13
CA1150242A (en)	1983-07-19
IE50506B1 (en)	1986-04-30
NO160370C (no)	1989-04-12
FI67552C (fi)	1985-04-10
GB2059420B (en)	1984-03-14
IL61117A (en)	1983-10-31
ES8106528A1 (es)	1981-08-16
EG14888A (en)	1985-06-30
KR840000796B1 (ko)	1984-06-12
IT8024920A0 (it)	1980-09-25
NO160370B (no)	1989-01-02
JPS5657788A (en)	1981-05-20
IE50507B1 (en)	1986-04-30
YU41733B (en)	1987-12-31
FI803028A7 (fi)	1981-03-27
FI840367A0 (fi)	1984-01-30
GR70065B (fi)	1982-07-26
ZA805132B (en)	1981-12-30
FR2465736B1 (fi)	1982-04-30
FI67552B (fi)	1984-12-31
SU959628A3 (ru)	1982-09-15
ES495354A0 (es)	1981-08-16
NO802836L (no)	1981-03-27
KR830003494A (ko)	1983-06-20
IE801998L (en)	1981-03-26
AU517074B2 (en)	1981-07-09
GB2125037A (en)	1984-02-29
GB2125037B (en)	1984-08-01
ATA474680A (de)	1981-08-15
MX6580E (es)	1985-07-24
PT71837B (en)	1981-07-09
US4256733A (en)	1981-03-17
CH645646A5 (fr)	1984-10-15
SE8005714L (sv)	1981-03-27
DE3035995C2 (de)	1985-01-10
IL61117A0 (en)	1980-11-30
SE449865B (sv)	1987-05-25
SE8500965D0 (sv)	1985-02-27

Publication	Publication Date	Title
FI781800A7 (fi)	1978-12-08	Penicillansyra-1,1-dioxider som beta-laktamas-inhibitorer
FI801546A7 (fi)	1980-11-17	Bis-estrar av metandiol med penicilliner och penicillansyra-1,1-dioxid
FI824281A0 (fi)	1982-12-14	Arrangemang foer en vals som anvaends vid pappersframstaellning, i synnerhet foer upphettning av en kalandervals samt en i samband med arrangemanget anvaend vals och dess anvaendning
NO803470L (no)	1981-07-02	Fremgangsmaate for fremstilling av 7-acylamino-3-vinylcefalosporansyrederivater.
NL7704210A (nl)	1977-10-25	Fenoxy-fenoxypropionzuurderivaten.
NO147385C (no)	1983-03-30	Anvendelse av kvadratsyrebisamider som stabiliseringsmiddel for plastmaterialer.
FI840367L (fi)	1984-01-30	Vid framstaellning av som mellanprodukter vid terapeutiskt anvaendbara 2 -acetoximetyl-2 -metyl-(5r)-penam-3 -karboxyksyra-1,1-dioxidderivat anvaenbara 2 -acetoxymetyl-2 -metyl-(5r)-penam-3 -karboxylsyraderivat
FI840920L (fi)	1984-03-07	Saosom mellanprodukter vid framstaellning av 9-amino-alkyl-9-aminokarbonylfluorenderivat anvaendbara 9-amino-9- cyanfluorener.
NO162343C (no)	1989-12-13	7-acylamino-1-detia-1-oksacefamforbindelser egnet som mellomprodukt for fremstilling av 7beta-acylamino-1-detia-1-oksacefalosporiner.
DK147337C (da)	1985-01-14	Krystallinsk 3,4-dihydro-2-methyl-4-oxo-2h-1,2-benzothiazin-3-carboxylsyre-1,1-dioxid til anvendelse som mellemprodukt ved fremstilling af 3,4-dihydro-2-methyl-4-oxo-2h-1,2-benzothiazin-3-carboxamid-1,1-dioxid-forbindelser og fremgangsmaade til fremstilling af syren
DK166353C (da)	1993-09-06	Penicillansyre-1,1-dioxid-derivater
FI792902A7 (fi)	1981-03-19	Foerfarande vid nedfaellningssortering av traevirke
NL7807871A (nl)	1979-01-30	Alpha-halogeenmethylaminozuur derivaten.
FI773707A7 (fi)	1978-06-23	Limningsanordning foer limning av lignocellulosahaltiga partiklar som anvaendes vid framstaellning av traematerialskivor
FI802009A7 (fi)	1981-01-01	Asyyliaminobentsoehappojohdannaiset.
FI782731A7 (fi)	1979-03-08	Foerfarande foer framstaellning av bromerade kefalosporansyraderivat
NL7804911A (nl)	1978-11-16	2-trichloormethyl-4-nitrobenzeensulfeenzuurderivaten.
FI801581A7 (fi)	1980-11-20	Foerfarande foer framstaellning av 6-beta-substituerade penicillansyraderivat
FI802163A7 (fi)	1981-01-11	Foerfaringssaett vid framstaellning av pappersmassa i hoegt utbyte
FI863598L (fi)	1987-03-07	Foerfarande foer framstaellning av 6-aminopenicillansyra-1,1-dioxid.
FI843981L (fi)	1984-10-10	2-azetidinderivat foer anvaendning som mellanprodukter vid framstaellning av terapeutiskt anvaendbara penemderivat.
NO834608L (no)	1977-10-17	2-(2-aminotiazol-4-yl)-2-oksyiminoeddiksyrederivater for bruk som mellomprodukter til fremstilling av terapeutisk virksomme forbindelser
NL7801435A (nl)	1978-08-18	Fenylpentaanzuur derivaten.
FI864576A7 (fi)	1988-05-12	Arrangemang foer kylning av ett centrifugalhjul som anvaends vid framstaellning av mineralullsfiber.
SE418291B (sv)	1981-05-18	4-bromfenyl-3-pyridylderivat som mellanprodukter vid framstellning av fenylpyridylaminer

Legal Events

Date	Code	Title	Description
2004-08-31	MM	Patent lapsed	Owner name: PFIZER INC.