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FI823575A0 - Anilinderivat, foerfarande foer deras framstaellning och hjaertmedicinkomposition - Google Patents

Anilinderivat, foerfarande foer deras framstaellning och hjaertmedicinkomposition

Info

Publication number
FI823575A0
FI823575A0 FI823575A FI823575A FI823575A0 FI 823575 A0 FI823575 A0 FI 823575A0 FI 823575 A FI823575 A FI 823575A FI 823575 A FI823575 A FI 823575A FI 823575 A0 FI823575 A0 FI 823575A0
Authority
FI
Finland
Prior art keywords
hjaertmedicinkomposition
anilinderivat
foerfarande foer
deras framstaellning
framstaellning och
Prior art date
Application number
FI823575A
Other languages
English (en)
Other versions
FI74704C (fi
FI74704B (fi
FI823575L (fi
Inventor
Michiaki Tominaga
Yung-Hsiung Yang
Hidenori Ogawa
Kazuyuki Nakagawa
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP56069690A external-priority patent/JPS57185273A/ja
Priority claimed from JP56178722A external-priority patent/JPS5879986A/ja
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of FI823575A0 publication Critical patent/FI823575A0/fi
Publication of FI823575L publication Critical patent/FI823575L/fi
Application granted granted Critical
Publication of FI74704B publication Critical patent/FI74704B/fi
Publication of FI74704C publication Critical patent/FI74704C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
FI823575A 1981-05-08 1982-10-19 Foerfarande foer framstaellning av terapeutiskt anvaendbara anilinderivat. FI74704C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP56069690A JPS57185273A (en) 1981-05-08 1981-05-08 Aniline derivative
JP6969081 1981-05-08
JP17872281 1981-11-06
JP56178722A JPS5879986A (ja) 1981-11-06 1981-11-06 アニリン誘導体
PCT/JP1982/000152 WO1982003861A1 (fr) 1981-05-08 1982-05-04 Derives d'aniline, procedes de preparation et toniques cardiaques
JP8200152 1982-05-04

Publications (4)

Publication Number Publication Date
FI823575A0 true FI823575A0 (fi) 1982-10-19
FI823575L FI823575L (fi) 1982-11-09
FI74704B FI74704B (fi) 1987-11-30
FI74704C FI74704C (fi) 1988-03-10

Family

ID=26410858

Family Applications (1)

Application Number Title Priority Date Filing Date
FI823575A FI74704C (fi) 1981-05-08 1982-10-19 Foerfarande foer framstaellning av terapeutiskt anvaendbara anilinderivat.

Country Status (13)

Country Link
US (1) US4585774A (fi)
EP (1) EP0064878B1 (fi)
KR (1) KR860000062B1 (fi)
AU (1) AU535498B2 (fi)
CA (1) CA1201121A (fi)
DE (1) DE3264889D1 (fi)
DK (1) DK159971C (fi)
ES (2) ES8306733A1 (fi)
FI (1) FI74704C (fi)
PH (1) PH18071A (fi)
PT (1) PT74858B (fi)
SU (1) SU1316560A3 (fi)
WO (1) WO1982003861A1 (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3315424A1 (de) * 1983-04-28 1984-12-20 Cassella Ag, 6000 Frankfurt Substituierte piperazin-1-yl-essigsaeure-amide, verfahren zu ihrer herstellung und ihre verwendung
US5164388A (en) * 1988-10-19 1992-11-17 Abbott Laboratories Heterocyclic peptide renin inhibitors
IL92011A0 (en) * 1988-10-19 1990-07-12 Abbott Lab Heterocyclic peptide renin inhibitors
US5719151A (en) * 1990-05-04 1998-02-17 Shall; Sydney Substituted benzene compounds
GB2244704B (en) * 1990-05-04 1995-05-17 Consultants Suppliers Limited Substituted benzene compounds
DE4302485A1 (de) * 1993-01-29 1994-08-04 Merck Patent Gmbh Piperazinderivate
DE4410822A1 (de) * 1994-03-24 1995-09-28 Schering Ag Neue Piperidin-Derivate

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143882A (fi) * 1966-06-21
FR2209560A1 (en) * 1972-12-07 1974-07-05 Degussa N-(Trialkoxyaroyl)-ethylenediamine derivs - useful as cardioactive medicaments, exhibit anti-ischaemic activity comparable to nitroglycerin
DE2304155A1 (de) * 1973-01-29 1974-08-01 Ichthyol Ges Cordes Hermanni & N-acylierte substituierte piperazinbzw. homopiperazinderivate, sowie verfahren zu ihrer herstellung
GB1561023A (en) * 1977-04-22 1980-02-13 Beecham Group Ltd 2-methoxy - 5 - chloro aniline derivatives

Also Published As

Publication number Publication date
ES512024A0 (es) 1983-06-01
DK159971B (da) 1991-01-07
FI74704C (fi) 1988-03-10
KR860000062B1 (ko) 1986-02-06
US4585774A (en) 1986-04-29
AU535498B2 (en) 1984-03-22
FI74704B (fi) 1987-11-30
DK465282A (da) 1982-11-09
FI823575L (fi) 1982-11-09
KR830010090A (ko) 1983-12-26
AU8400082A (en) 1982-12-07
SU1316560A3 (ru) 1987-06-07
EP0064878B1 (en) 1985-07-24
DE3264889D1 (en) 1985-08-29
ES8403469A1 (es) 1984-03-16
DK159971C (da) 1991-05-27
CA1201121A (en) 1986-02-25
ES8306733A1 (es) 1983-06-01
EP0064878A1 (en) 1982-11-17
PH18071A (en) 1985-03-18
ES519853A0 (es) 1984-03-16
PT74858B (en) 1983-12-07
PT74858A (en) 1982-06-01
WO1982003861A1 (fr) 1982-11-11

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Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: OTSUKA PHARMACEUTICAL CO., LTD.