FI813408L - Karbostyril-foereningar kompositioner innehaollande dessa och foerfarande foer deras framstaellning - Google Patents

Karbostyril-foereningar kompositioner innehaollande dessa och foerfarande foer deras framstaellning

Info

Publication number: FI813408L
Authority: FI; Finland
Prior art keywords: foereningar; carbostyril; foerfarande foer; och foerfarande; deras framstaellning
Prior art date: 1980-10-31

Application number

FI813408A

Other languages

English (en)

Other versions

FI77450B (fi

FI77450C (fi

Inventor

Michiaki Tominaga

Yung-Hsiung Yang

Hidenori Ogawa

Kazuyuki Nakagawa

Original Assignee

Otsuka Pharma Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-10-31

Filing date

1981-10-30

Publication date

1982-05-01

1981-10-30 Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd

1982-05-01 Publication of FI813408L publication Critical patent/FI813408L/fi

1988-11-30 Publication of FI77450B publication Critical patent/FI77450B/fi

1989-03-10 Application granted granted Critical

1989-03-10 Publication of FI77450C publication Critical patent/FI77450C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/40—Nitrogen atoms attached in position 8
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Heart & Thoracic Surgery (AREA)
General Health & Medical Sciences (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Quinoline Compounds (AREA)

FI813408A 1980-10-31 1981-10-30 Foerfarande foer framstaellning av piperazinylsubstituerade karbostyrilderivat, vilka aer anvaendbara som kardiotoniska medel. FI77450C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP55154071A JPS5777676A (en)	1980-10-31	1980-10-31	Carbostyril derivative
JP15407180		1980-10-31

Publications (3)

Publication Number	Publication Date
FI813408L true FI813408L (fi)	1982-05-01
FI77450B FI77450B (fi)	1988-11-30
FI77450C FI77450C (fi)	1989-03-10

Family

ID=15576252

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI813408A FI77450C (fi)	1980-10-31	1981-10-30	Foerfarande foer framstaellning av piperazinylsubstituerade karbostyrilderivat, vilka aer anvaendbara som kardiotoniska medel.

Country Status (24)

Country	Link
US (1)	US4415572A (fi)
JP (1)	JPS5777676A (fi)
KR (1)	KR860001944B1 (fi)
AR (2)	AR242563A1 (fi)
AT (1)	AT381701B (fi)
AU (1)	AU524419B2 (fi)
BE (1)	BE890942A (fi)
CA (1)	CA1209575A (fi)
CH (2)	CH650782A5 (fi)
DE (2)	DE3142982C2 (fi)
DK (1)	DK155665C (fi)
ES (3)	ES8306743A1 (fi)
FI (1)	FI77450C (fi)
FR (2)	FR2493320B1 (fi)
GB (1)	GB2086896B (fi)
IT (2)	IT1210585B (fi)
MX (1)	MX8481A (fi)
NL (2)	NL194205C (fi)
NO (1)	NO158099C (fi)
PH (1)	PH17962A (fi)
PT (1)	PT73910B (fi)
SE (2)	SE448877B (fi)
SU (1)	SU1426452A3 (fi)
ZA (1)	ZA817515B (fi)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
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JPS5883677A (ja) *	1981-11-11	1983-05-19	Otsuka Pharmaceut Co Ltd	カルボスチリル誘導体
JPS5929667A (ja) *	1982-08-13	1984-02-16	Otsuka Pharmaceut Co Ltd	カルボスチリル誘導体および強心剤
CH655110A5 (de) *	1982-09-03	1986-03-27	Otsuka Pharma Co Ltd	Carbostyrilderivate, verfahren zu deren herstellung und arzneimittel, welche diese enthalten.
US4730000A (en) *	1984-04-09	1988-03-08	Abbott Laboratories	Quinoline antibacterial compounds
AU577802B2 (en) *	1983-10-17	1988-10-06	Duphar International Research B.V.	Blood-pressure lowering piperazine derivatives
JPS60126270A (ja) *	1983-12-14	1985-07-05	Otsuka Pharmaceut Co Ltd	カルボスチリル誘導体
US4710507A (en) *	1983-12-22	1987-12-01	Pfizer Inc.	Quinolone inotropic agents
US4774246A (en) *	1984-01-26	1988-09-27	Abbott Laboratories	Quinoline antibacterial compounds
CA1292234C (en) *	1984-05-29	1991-11-19	Simon Fraser Campbell	Heterocyclic-substituted quinolone inotropic agents
JPS60256133A (ja) *	1984-06-01	1985-12-17	Fuji Photo Film Co Ltd	放射線画像情報記録読取装置
EP0168003B1 (en) *	1984-07-06	1991-04-03	Otsuka Pharmaceutical Co., Ltd.	Oxindol compounds, compositions containing same and processes for preparing same
JPH07100696B2 (ja) *	1984-12-18	1995-11-01	大塚製薬株式会社	カルボスチリル誘導体
US4760064A (en) *	1984-12-18	1988-07-26	Otsuka Pharmaceutical Co., Ltd.	Carbostyril compounds, compositions containing same and processes for preparing same
JPS61145162A (ja) *	1984-12-19	1986-07-02	Otsuka Pharmaceut Co Ltd	カルボスチリル誘導体
EP0185429A1 (en) *	1984-12-21	1986-06-25	Duphar International Research B.V	New bicyclic heteroaryl piperazines
DE3586794T2 (de) *	1984-12-21	1993-05-27	Duphar Int Res	Arzneimittel mit psychotroper wirkung.
US4845100A (en) *	1985-04-12	1989-07-04	Otsuka Pharmaceutical Co., Ltd.	Carbostyril derivatives and salts thereof, processes for preparing the same and cardiotonic composition containing the same
DE3524067A1 (de) *	1985-07-05	1987-01-08	Boehringer Mannheim Gmbh	Neue benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte
US4666913A (en) *	1985-11-22	1987-05-19	William H. Rorer, Inc.	Hydroxy and aminothiazolyl-benzodiazinone compounds, cardiotonic compositions including the same, and their uses
GB8529362D0 (en) *	1985-11-28	1986-01-02	Pfizer Ltd	Quinolone cardiac stimulants
JPH0625123B2 (ja) *	1985-12-12	1994-04-06	大塚製薬株式会社	カルボスチリル誘導体−シクロデキストリン包接化合物
US4689325A (en) *	1985-12-23	1987-08-25	Abbott Laboratories	Isoxazolo-pyrido-phenoxazine and isothiazolo-pyrido-phenoxazine derivatives
US4687770A (en) *	1985-12-23	1987-08-18	Abbott Laboratories	Isoxazolo-pyrido-benzoxazine and isothiazolo-pyrido-benzoxazine derivatives
DK111387A (da) *	1986-03-05	1987-09-06	Otsuka Pharma Co Ltd	Carbostyrilderivater og salte deraf, laegemiddel indeholdende saadanne derivater samt fremgangsmaade til fremstilling af derivaterne
US5358949A (en) *	1986-03-05	1994-10-25	Otsuka Pharmaceutical Co., Ltd.	Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives
GB8630702D0 (en) *	1986-12-23	1987-02-04	Wellcome Found	Quinoline compound
US5166160A (en) *	1986-12-23	1992-11-24	Burroughs Wellcome Co.	Quinoline compound
JPS63225357A (ja) *	1987-03-12	1988-09-20	Otsuka Pharmaceut Co Ltd	カルボスチリル誘導体
GB8827189D0 (en) *	1988-11-21	1988-12-29	Fujisawa Pharmaceutical Co	2(1h)-quinolinone compounds processes for preparation thereof & pharmaceutical composition comprising same
AU648690B2 (en) *	1991-07-03	1994-04-28	Otsuka Pharmaceutical Co., Ltd.	Apoptosis regulator
US5543412A (en) *	1991-07-03	1996-08-06	Otsuka Pharmaceutical Co., Ltd.	Hepatitis treatment with carbostyril compounds
WO1993011769A1 (fr) *	1991-12-10	1993-06-24	Otsuka Pharmaceutical Co., Ltd	Agent anticancereux
JP2686887B2 (ja) *	1992-08-11	1997-12-08	キッセイ薬品工業株式会社	ピペリジノ−３，４−ジヒドロカルボスチリル誘導体
US5464833A (en) *	1992-08-19	1995-11-07	Otsuka Pharmaceutical Co., Ltd.	Apoptosis regulating composition
JP2826790B2 (ja) *	1992-12-26	1998-11-18	キッセイ薬品工業株式会社	３，４−ジヒドロカルボスチリル誘導体
AU672288B2 (en) *	1993-03-02	1996-09-26	Akira Matsumori	Rejection inhibitor for transplants and IL-1 production inhibitor
JPH0733664A (ja) *	1993-07-26	1995-02-03	Otsuka Pharmaceut Co Ltd	平滑筋細胞増殖抑制剤
GB9326373D0 (en) *	1993-12-23	1994-02-23	Zeneca Ltd	Chemical compounds
GB9326232D0 (en) *	1993-12-23	1994-02-23	Zeneca Ltd	Chemical compounds
US5504093A (en) *	1994-08-01	1996-04-02	Otsuka Pharmaceutical Co., Ltd.	Method for inhibiting nucleoside and nucleobase transport in mammalian cells, and method for inhibition of DNA virus replication
WO1997036893A1 (en) *	1996-03-29	1997-10-09	Duphar International Research B.V.	Piperazine and piperidine compounds
GB2312843A (en) *	1996-05-07	1997-11-12	Merck & Co Inc	Method of treating rheumatoid arthritis
US5684007A (en) *	1996-09-05	1997-11-04	Otsuka Pharmaceutical Co., Ltd.	Methods for inhibiting cardiac fibroblast growth and cardiac fibrosis
AU6941200A (en)	1999-08-27	2001-03-26	Ligand Pharmaceuticals Incorporated	8-substituted-6-trifluoromethyl-9-pyrido(3,2-g)quinoline compounds as androgen receptor modulators
JP2003508402A (ja) *	1999-08-27	2003-03-04	リガンド・ファーマシューティカルズ・インコーポレイテッド	アンドロゲン受容体モジュレーター化合物および方法
US6566372B1 (en) *	1999-08-27	2003-05-20	Ligand Pharmaceuticals Incorporated	Bicyclic androgen and progesterone receptor modulator compounds and methods
EP1216221A2 (en)	1999-09-14	2002-06-26	Ligand Pharmaceuticals Incorporated	Rxr modulators with improved pharmacologic profile
US7772188B2 (en)	2003-01-28	2010-08-10	Ironwood Pharmaceuticals, Inc.	Methods and compositions for the treatment of gastrointestinal disorders
MXPA06001751A (es) *	2003-08-22	2006-05-12	Ligand Pharm Inc	Derivados de 6-cicloamino-2-quinolinona como compuestos moduladores de receptor de androgeno.
EP1865951A1 (en) *	2005-03-14	2007-12-19	Nycomed GmbH	Method for preventing cardiovascular diseases
US8993763B2 (en) *	2005-09-27	2015-03-31	Shionogi & Co., Ltd.	Sulfonamide derivative having PGD2 receptor antagonistic activity
US8969514B2 (en)	2007-06-04	2015-03-03	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
JP5546451B2 (ja)	2007-06-04	2014-07-09	シナジーファーマシューティカルズインコーポレイテッド	胃腸の障害、炎症、癌および他の障害の処置に有用なグアニル酸シクラーゼのアゴニスト
US20100120694A1 (en)	2008-06-04	2010-05-13	Synergy Pharmaceuticals, Inc.	Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders
EP3241839B1 (en)	2008-07-16	2019-09-04	Bausch Health Ireland Limited	Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en)	2010-09-15	2017-04-11	Synergy Pharmaceuticals, Inc.	Formulations of guanylate cyclase C agonists and methods of use
CN108676076A (zh)	2011-03-01	2018-10-19	辛纳吉制药公司	制备鸟苷酸环化酶c激动剂的方法
EP3718557A3 (en)	2013-02-25	2020-10-21	Bausch Health Ireland Limited	Guanylate cyclase receptor agonist sp-333 for use in colonic cleansing
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HK1220696A1 (zh)	2013-03-15	2017-05-12	Bausch Health Ireland Limited	鸟苷酸环化酶激动剂及其用途
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DE1278385B (de) *	1965-03-30	1968-09-26	Bayer Ag	Aufhellungsmittel
GB1299172A (en) *	1968-10-15	1972-12-06	Lilly Industries Ltd	Heterocyclic anti-inflammatory agents
DE2719562C2 (de) *	1976-05-08	1986-05-07	Otsuka Pharmaceutical Co. Ltd., Tokio/Tokyo	3, 4-Dihydrocarbostyrilderivate, Verfahren zu deren Herstellung und Arzneimittel, welche diese enthalten
JPS54130589A (en) *	1978-03-31	1979-10-09	Yoshitomi Pharmaceut Ind Ltd	Pyridazine derivative and its preparation
JPS54135785A (en) *	1978-04-12	1979-10-22	Yoshitomi Pharmaceut Ind Ltd	Pyridazinone derivative and its preparation
JPS54138585A (en) *	1978-04-18	1979-10-27	Yoshitomi Pharmaceut Ind Ltd	Pyridazine derivative and its preparation
JPS54141785A (en) *	1978-04-26	1979-11-05	Yoshitomi Pharmaceut Ind Ltd	Preparation of carboxylic acid derivative
JPS6017072B2 (ja) *	1978-09-05	1985-04-30	三菱電機株式会社	赤熱金属検出器
JPS5549319A (en) *	1978-10-06	1980-04-09	Yoshitomi Pharmaceut Ind Ltd	Remedy for suppression of blood platelet-agglutination
JPS5553283A (en) *	1978-10-12	1980-04-18	Yoshitomi Pharmaceut Ind Ltd	Pyridazinone derivative
JPS5576872A (en) *	1978-12-06	1980-06-10	Yoshitomi Pharmaceut Ind Ltd	Imidazolidinone derivative
JPS5583781A (en) *	1978-12-19	1980-06-24	Yoshitomi Pharmaceut Ind Ltd	Pyridazinone derivative

1980
- 1980-10-31 JP JP55154071A patent/JPS5777676A/ja active Granted
1981
- 1981-10-29 DE DE3142982A patent/DE3142982C2/de not_active Expired
- 1981-10-29 IT IT8149588A patent/IT1210585B/it active
- 1981-10-29 ES ES507198A patent/ES8306743A1/es not_active Expired
- 1981-10-29 SU SU813349303A patent/SU1426452A3/ru active
- 1981-10-29 ZA ZA817515A patent/ZA817515B/xx unknown
- 1981-10-29 DE DE3153260A patent/DE3153260C2/de not_active Expired
- 1981-10-29 AT AT0460281A patent/AT381701B/de not_active IP Right Cessation
- 1981-10-29 CA CA000389068A patent/CA1209575A/en not_active Expired
- 1981-10-30 SE SE8106430A patent/SE448877B/sv not_active IP Right Cessation
- 1981-10-30 NO NO813678A patent/NO158099C/no not_active IP Right Cessation
- 1981-10-30 BE BE0/206407A patent/BE890942A/fr not_active IP Right Cessation
- 1981-10-30 AU AU76996/81A patent/AU524419B2/en not_active Expired
- 1981-10-30 CH CH6942/81A patent/CH650782A5/de not_active IP Right Cessation
- 1981-10-30 NL NL8104923A patent/NL194205C/nl not_active IP Right Cessation
- 1981-10-30 CH CH199/85A patent/CH656616A5/de not_active IP Right Cessation
- 1981-10-30 GB GB8132743A patent/GB2086896B/en not_active Expired
- 1981-10-30 FR FR8120470A patent/FR2493320B1/fr not_active Expired
- 1981-10-30 PH PH26427A patent/PH17962A/en unknown
- 1981-10-30 PT PT73910A patent/PT73910B/pt unknown
- 1981-10-30 FI FI813408A patent/FI77450C/fi not_active IP Right Cessation
- 1981-10-30 DK DK480381A patent/DK155665C/da not_active IP Right Cessation
- 1981-10-30 US US06/316,572 patent/US4415572A/en not_active Expired - Lifetime
- 1981-10-31 KR KR1019810004240A patent/KR860001944B1/ko not_active Expired
1983
- 1983-03-15 ES ES520638A patent/ES520638A0/es active Granted
- 1983-03-15 ES ES520637A patent/ES8403885A1/es not_active Expired
- 1983-05-06 AR AR83292954A patent/AR242563A1/es active
1984
- 1984-03-21 AR AR84296053A patent/AR242375A1/es active
- 1984-10-11 NL NL8403096A patent/NL8403096A/nl not_active Application Discontinuation
- 1984-10-19 FR FR848416085A patent/FR2552760B1/fr not_active Expired
- 1984-12-06 SE SE8406209A patent/SE466655B/sv not_active IP Right Cessation
1985
- 1985-03-26 IT IT8547867A patent/IT1226479B/it active
- 1985-08-09 MX MX848185A patent/MX8481A/es unknown

Also Published As

Publication number	Publication date
ES507198A0 (es)	1983-06-16
FR2552760B1 (fr)	1988-08-05
MX8481A (es)	1994-02-28
AU7699681A (en)	1982-05-06
IT1226479B (it)	1991-01-16
ZA817515B (en)	1982-10-27
CH650782A5 (de)	1985-08-15
SE8406209D0 (sv)	1984-12-06
NL194205C (nl)	2001-09-04
NL8104923A (nl)	1982-05-17
FR2493320B1 (fr)	1985-08-23
NO158099B (no)	1988-04-05
DK155665C (da)	1989-09-04
SE8406209L (sv)	1984-12-06
DK155665B (da)	1989-05-01
ES520637A0 (es)	1984-04-16
SE448877B (sv)	1987-03-23
NL194205B (nl)	2001-05-01
GB2086896A (en)	1982-05-19
AR242375A1 (es)	1993-03-31
US4415572A (en)	1983-11-15
NL8403096A (nl)	1985-02-01
DK480381A (da)	1982-05-01
FI77450B (fi)	1988-11-30
ATA460281A (de)	1986-04-15
NO158099C (no)	1988-07-13
ES8403886A1 (es)	1984-04-16
PH17962A (en)	1985-02-20
IT8547867A0 (it)	1985-03-26
SU1426452A3 (ru)	1988-09-23
DE3142982A1 (de)	1982-06-24
FR2493320A1 (fr)	1982-05-07
KR830007607A (ko)	1983-11-04
IT1210585B (it)	1989-09-14
PT73910B (en)	1983-04-18
KR860001944B1 (ko)	1986-11-01
SE466655B (sv)	1992-03-16
FR2552760A1 (fr)	1985-04-05
FI77450C (fi)	1989-03-10
ES8403885A1 (es)	1984-04-16
IT8149588A0 (it)	1981-10-29
ES520638A0 (es)	1984-04-16
AT381701B (de)	1986-11-25
GB2086896B (en)	1984-10-10
AU524419B2 (en)	1982-09-16
BE890942A (fr)	1982-02-15
JPH0143747B2 (fi)	1989-09-22
CH656616A5 (de)	1986-07-15
AR242563A1 (es)	1993-04-30
CA1209575A (en)	1986-08-12
DE3153260C2 (fi)	1989-05-24
DE3153260A1 (fi)	1985-05-15
JPS5777676A (en)	1982-05-15
SE8106430L (sv)	1982-05-01
PT73910A (en)	1981-11-01
ES8306743A1 (es)	1983-06-16
DE3142982C2 (de)	1985-12-19
NO813678L (no)	1982-05-03

Publication	Publication Date	Title
FI811762L (fi)	1981-12-07	Ml-236b-derivater och deras framstaellning
FI812652L (fi)	1982-03-01	Aminosyraderivat foerfarande foer deras framstaellning dessa innehaollande aemnen och deras anvaendning
FI813346L (fi)	1982-04-29	Foerpackningar och omslag foer multienheter
FI813408L (fi)	1982-05-01	Karbostyril-foereningar kompositioner innehaollande dessa och foerfarande foer deras framstaellning
FI811422L (fi)	1981-11-15	Anordning foer stamkvistning och roejning
FI813872L (fi)	1982-06-10	Blekningsaktivator-korn och deras framstaellning
FI813526L (fi)	1982-05-11	Bensoheterocykliska foereningar och foerfarande foer deras framstaellning
FI802279A7 (fi)	1982-01-19	Ytbelagt titandioxidpigment och foerfarande foer framstaellning daerav
FI811591L (fi)	1981-12-01	Stickugn och i denna infoerbar stickvagn
FI810712L (fi)	1981-09-09	Heterocykliska foereningar deras framstaellning och anvaendning
FI802106A7 (fi)	1982-01-02	Torkningsfoerfarande och anordning
FI801356A7 (fi)	1981-10-29	Kodsystem i flerkanalanalysanordning och anordning foer systemet
FI810718L (fi)	1981-09-14	Slitbana foer daeck och daeck innehaollande en dylik slitbana
FI814163L (fi)	1982-07-01	Laodgjutningsfoerfarande och gjutanordning
FI813524L (fi)	1982-05-12	Maleinsyra-anhydridkopolymerater och deras framstaellning
FI812215L (fi)	1982-06-17	7-substituerade benzopyrander och foerfarande foer deras framstaellning
FI812504L (fi)	1982-02-15	Desinfekterande och steriliserande komposition
FI811532L (fi)	1981-11-23	Dioxidfoereningar foerfaranden foer deras framstaellning och deras anvaendning
FI813604L (fi)	1981-11-13	Sek -butylbifenylprodukt och foerfarande foer framstaellning daerav
FI800647A7 (fi)	1981-09-04	Saett och anordning foer foerstyvning och raetning av startplaotar
FI810916L (fi)	1981-11-28	Kirurgiskt haeftningsinstrument och styranordning
FI811900L (fi)	1981-12-22	Larvicider och insekticider
FI801037A7 (fi)	1981-10-02	Foerfarande foer tillverkning och hopsaettning av laosdelar
FI823488A0 (fi)	1982-10-13	Aromatiska formaldehydkompositioner och tandvaordskompositioner och tandvaordskompositioner innehaollande dessa
FI812206L (fi)	1982-01-22	Vaermekamin och vaermevaexlare foer vaermekamin

Legal Events

Date	Code	Title	Description
2004-08-31	MA	Patent expired	Owner name: OTSUKA PHARMACEUTICAL CO. LTD.