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FI20030370A7 - Uusia yhdisteitä - Google Patents

Uusia yhdisteitä Download PDF

Info

Publication number
FI20030370A7
FI20030370A7 FI20030370A FI20030370A FI20030370A7 FI 20030370 A7 FI20030370 A7 FI 20030370A7 FI 20030370 A FI20030370 A FI 20030370A FI 20030370 A FI20030370 A FI 20030370A FI 20030370 A7 FI20030370 A7 FI 20030370A7
Authority
FI
Finland
Prior art keywords
new associations
preparing
compounds
methods
substantially free
Prior art date
Application number
FI20030370A
Other languages
English (en)
Swedish (sv)
Other versions
FI20030370L (fi
Inventor
Victor Witold Jacewicz
Neal Ward
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27267578&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI20030370(A7) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9502297.6A external-priority patent/GB9502297D0/en
Priority claimed from GBGB9503112.6A external-priority patent/GB9503112D0/en
Priority claimed from GBGB9509807.5A external-priority patent/GB9509807D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of FI20030370L publication Critical patent/FI20030370L/fi
Publication of FI20030370A7 publication Critical patent/FI20030370A7/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Keksintö koskee paroksetiinihydrokloridin anhydraattia, joka on sitoutunutta propan-2-olia oleellisesti sisältämätön, sen erilaisia muotoja, menetelmiä mainittujen yhdisteiden valmistamiseksi, uusia välituotteita, jotka ovat käyttökelpoisia valmistettaessa mainittuja yhdisteitä.
FI20030370A 1995-02-06 2003-03-12 Uusia yhdisteitä FI20030370A7 (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9502297.6A GB9502297D0 (en) 1995-02-06 1995-02-06 Novel compound
GBGB9503112.6A GB9503112D0 (en) 1995-02-17 1995-02-17 Novel compound
GBGB9509807.5A GB9509807D0 (en) 1995-05-15 1995-05-15 Novel compounds

Publications (2)

Publication Number Publication Date
FI20030370L FI20030370L (fi) 2003-03-12
FI20030370A7 true FI20030370A7 (fi) 2003-03-12

Family

ID=27267578

Family Applications (3)

Application Number Title Priority Date Filing Date
FI960519A FI111544B (fi) 1995-02-06 1996-02-05 Menetelmä sitoutunutta orgaanista liuotinta oleellisesti sisältämättömän paroksetiinihydrokloridin anhydraatin valmistamiseksi
FI20030162A FI20030162A7 (fi) 1995-02-06 2003-02-03 Uusia yhdisteitä
FI20030370A FI20030370A7 (fi) 1995-02-06 2003-03-12 Uusia yhdisteitä

Family Applications Before (2)

Application Number Title Priority Date Filing Date
FI960519A FI111544B (fi) 1995-02-06 1996-02-05 Menetelmä sitoutunutta orgaanista liuotinta oleellisesti sisältämättömän paroksetiinihydrokloridin anhydraatin valmistamiseksi
FI20030162A FI20030162A7 (fi) 1995-02-06 2003-02-03 Uusia yhdisteitä

Country Status (47)

Country Link
EP (3) EP1136490B1 (fi)
JP (2) JP2915338B2 (fi)
KR (1) KR100289885B1 (fi)
CN (3) CN1090187C (fi)
AR (2) AR001982A1 (fi)
AT (1) AT407528B (fi)
AU (2) AU4786496A (fi)
BE (1) BE1009112A3 (fi)
BG (1) BG62967B1 (fi)
BR (1) BR9600534A (fi)
CA (4) CA2168829C (fi)
CH (3) CH689804A5 (fi)
CZ (1) CZ297171B6 (fi)
DE (3) DE69631298T2 (fi)
DK (2) DK11996A (fi)
DZ (1) DZ1989A1 (fi)
ES (1) ES2114471B1 (fi)
FI (3) FI111544B (fi)
FR (1) FR2730232B1 (fi)
GR (1) GR1002466B (fi)
HK (1) HK59397A (fi)
HU (1) HUP9600255A1 (fi)
IE (1) IE80500B1 (fi)
IL (1) IL117035A (fi)
IT (1) IT1289532B1 (fi)
LU (1) LU88711A1 (fi)
LV (1) LV11618B (fi)
MA (1) MA23802A1 (fi)
MC (1) MC2411A1 (fi)
MX (1) MX9600484A (fi)
MY (1) MY132529A (fi)
NL (1) NL1002248C2 (fi)
NO (3) NO301009B1 (fi)
NZ (1) NZ280943A (fi)
OA (1) OA10261A (fi)
PL (1) PL189247B1 (fi)
PT (1) PT101827B (fi)
RO (1) RO112426B1 (fi)
RU (1) RU2125052C1 (fi)
SE (1) SE521084C2 (fi)
SG (1) SG43787A1 (fi)
SI (2) SI21923B (fi)
SK (1) SK283608B6 (fi)
TR (1) TR199600096A2 (fi)
TW (1) TW503238B (fi)
UA (1) UA49796C2 (fi)
WO (1) WO1996024595A1 (fi)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3882224B2 (ja) 1996-05-31 2007-02-14 旭硝子株式会社 パロキセチンの製造方法
EP1384720A1 (en) * 1996-06-13 2004-01-28 SUMIKA FINE CHEMICALS Co., Ltd. Process for drying paroxetine hydrochloride
JP2000514653A (ja) * 1996-07-15 2000-11-07 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー 立体特異的分割のためのエステラーゼのスクリーニングおよびその使用
US6638948B1 (en) 1996-09-09 2003-10-28 Pentech Pharmaceuticals, Inc. Amorphous paroxetine composition
US5672612A (en) * 1996-09-09 1997-09-30 Pentech Pharmaceuticals, Inc. Amorphous paroxetine composition
CA2193939C (en) * 1996-12-24 2002-02-12 K.S. Keshava Murthy Useful form of anhydrous paroxetine hydrochloride
ES2155995T3 (es) * 1997-06-10 2001-06-01 Synthon Bv Compuestos de 4-fenilpiperidina.
PT903345E (pt) * 1997-08-08 2001-01-31 Aventis Pharma Gmbh Forma cristalina de n-(4-trifluorometilfenil)-5-metil-isoxazolo-4-carboxamida
GB9726907D0 (en) * 1997-12-19 1998-02-18 Smithkline Beecham Plc Novel compounds
EA200000946A1 (ru) * 1998-03-16 2001-02-26 Смитклайн Бичам Плс Кристаллическая форма пароксетина
US6699882B2 (en) 1998-03-24 2004-03-02 Smithkline Beecham P.L.C. Paroxetine compositions
GB9806312D0 (en) * 1998-03-24 1998-05-20 Smithkline Beecham Plc Novel formulations
AU2003200534B2 (en) * 1998-03-24 2004-12-02 Smithkline Beecham Plc Paroxetine compositions
JP3796351B2 (ja) 1998-04-13 2006-07-12 住友化学株式会社 パロキセチン塩酸塩無水和物の乾燥方法
GB9812941D0 (en) * 1998-06-16 1998-08-12 Smithkline Beecham Plc Method of treatment
CH689805A8 (fr) * 1998-07-02 2000-02-29 Smithkline Beecham Plc Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant.
ES2138937B1 (es) 1998-07-07 2000-10-01 Medichem Sa Polimorfo de maleato de paroxetina y formulaciones farmaceuticas que lo contienen.
PL345885A1 (en) * 1998-08-07 2002-01-14 Smithkline Beecham Plc Process for the preparation of a non-crystalline anhydrate form of paroxetine hydrochloride
GB9824298D0 (en) * 1998-11-05 1998-12-30 Smithkline Beecham Plc Novel process
GB9826176D0 (en) * 1998-11-28 1999-01-20 Smithkline Beecham Plc Novel process
GB9826175D0 (en) * 1998-11-28 1999-01-20 Smithkline Beecham Plc Novel process
ES2211232T3 (es) * 1998-11-30 2004-07-01 Smithkline Beecham Plc Solvatos mixtos de paroxetina-propan-2-ol.
GB9826178D0 (en) * 1998-11-30 1999-01-20 Smithkline Beecham Plc Novel process
GB9826180D0 (en) * 1998-11-30 1999-01-20 Smithkline Beecham Plc Novel process
GB9826242D0 (en) * 1998-11-30 1999-01-20 Smithkline Beecham Plc Novel process
GB9826171D0 (en) * 1998-11-30 1999-01-20 Smithkline Beecham Plc Novel compounds
GB9828767D0 (en) * 1998-12-29 1999-02-17 Smithkline Beecham Plc Novel process
IT1308629B1 (it) * 1999-02-23 2002-01-09 Recordati Chem Pharm Processo per la produzione di paroxetina.
ATE311883T1 (de) * 1999-03-12 2005-12-15 Aesica Pharmaceuticals Ltd Stabile pharmazeutische anwendungsform für paroxetin-anhydrat
GB9914583D0 (en) * 1999-06-22 1999-08-25 Smithkline Beecham Plc Novel process
GB9914585D0 (en) * 1999-06-22 1999-08-25 Smithkline Beecham Plc Novel process
SE9902550D0 (sv) * 1999-07-02 1999-07-02 Astra Ab New crystalline forms
GB9919001D0 (en) * 1999-08-12 1999-10-13 Smithkline Beecham Plc Novel process
GB9923446D0 (en) * 1999-10-04 1999-12-08 Smithkline Beecham Plc Novel process
GB9923439D0 (en) * 1999-10-04 1999-12-08 Smithkline Beecham Plc Novel process
GB9923445D0 (en) * 1999-10-04 1999-12-08 Smithkline Beecham Plc Novel process
HU226912B1 (en) * 2000-04-07 2010-03-01 Richter Gedeon Nyrt New paroxetin salt and medicament containing it
WO2002022609A1 (en) * 2000-09-14 2002-03-21 Asahi Glass Company, Limited Process for producing paroxetine salt containing substantially no organic solvent
CA2476723A1 (en) * 2002-02-22 2003-09-04 Gideon Pilarski Preparation of paroxetine involving novel intermediates
US7563930B2 (en) * 2005-11-22 2009-07-21 Teva Pharmaceutical Industries Ltd Crystal forms of Cinacalcet HCI and processes for their preparation

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1422263A (en) * 1973-01-30 1976-01-21 Ferrosan As 4-phenyl-piperidine compounds
GB8430581D0 (en) * 1984-12-04 1985-01-09 Ferrosan As Treatment
DE3688827T2 (de) * 1985-10-25 1994-03-31 Beecham Group Plc Piperidinderivat, seine Herstellung und seine Verwendung als Arzneimittel.
US5017585A (en) * 1986-11-03 1991-05-21 Novo Nordisk A/S Method of treating calcium overload
GB8626936D0 (en) * 1986-11-11 1986-12-10 Ferrosan As Treatment
DK715988D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Etherifikation og dealkylering af piperidin-derivater samt intermediater
DK716088D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Reduktion af piperidin-dion-derivater samt intermediat
CA2096853A1 (en) * 1990-11-24 1992-05-25 Anthony Michael Johnson Use of paroxetine for the treatment of senile dementia, bulimia, migraine or anorexia
US5258517A (en) * 1992-08-06 1993-11-02 Sepracor, Inc. Method of preparing optically pure precursors of paroxetine
GB9325644D0 (en) * 1993-12-15 1994-02-16 Smithkline Beecham Plc Novel formulation

Also Published As

Publication number Publication date
AT407528B (de) 2001-04-25
CH688353A5 (de) 1997-08-15
CA2210023A1 (en) 1996-08-07
HU9600255D0 (en) 1996-03-28
IL117035A (en) 2000-02-29
EP0808314A1 (en) 1997-11-26
IL117035A0 (en) 1996-09-12
DE19603797A1 (de) 1996-08-14
CN1636993A (zh) 2005-07-13
JPH11228571A (ja) 1999-08-24
WO1996024595A1 (en) 1996-08-15
MC2411A1 (fr) 1996-12-02
MX9600484A (es) 1997-01-31
RU2125052C1 (ru) 1999-01-20
ITMI960203A0 (fi) 1996-02-05
NO970939D0 (no) 1997-02-28
NO311519B1 (no) 2001-12-03
CN1090187C (zh) 2002-09-04
TW503238B (en) 2002-09-21
NO301009B3 (fi) 2003-01-06
CN1143643A (zh) 1997-02-26
FI111544B (fi) 2003-08-15
SE521084C2 (sv) 2003-09-30
UA49796C2 (uk) 2002-10-15
JPH08245620A (ja) 1996-09-24
OA10261A (en) 1997-09-19
KR960031409A (ko) 1996-09-17
PT101827B (pt) 1997-08-29
NO20015070D0 (no) 2001-10-18
GR1002466B (el) 1996-11-06
CA2168829A1 (en) 1996-08-07
EP1136490A1 (en) 2001-09-26
HUP9600255A1 (en) 1997-03-28
ATA21096A (de) 2000-08-15
FI20030162L (fi) 2003-02-03
CA2211522A1 (en) 1996-08-07
LV11618B (en) 1997-04-20
BR9600534A (pt) 1997-05-13
NO301009B1 (no) 1997-09-01
NO970939L (no) 1996-08-07
AU701518C (en) 2006-12-07
MA23802A1 (fr) 1996-10-01
CH689804A5 (de) 1999-11-30
RO112426B1 (ro) 1997-09-30
FI20030162A7 (fi) 2003-02-03
SK283608B6 (sk) 2003-10-07
AR036856A2 (es) 2004-10-06
ES2114471A1 (es) 1998-05-16
SI9600036A (en) 1996-10-31
AR001982A1 (es) 1998-01-07
IT1289532B1 (it) 1998-10-15
NL1002248A1 (nl) 1996-08-06
SI21923B (sl) 2006-12-31
BG100333A (bg) 1996-08-30
IE80500B1 (en) 1998-08-12
SG43787A1 (en) 1997-11-14
AU4786496A (en) 1996-08-27
FI960519L (fi) 1996-08-07
FI20030370L (fi) 2003-03-12
PL189247B1 (pl) 2005-07-29
SE9600406L (sv) 1996-08-07
DE69631298D1 (de) 2004-02-12
NL1002248C2 (nl) 1996-09-11
DE69631298T2 (de) 2004-11-18
FR2730232A1 (fr) 1996-08-09
AU701518B2 (en) 1999-01-28
LU88711A1 (fr) 1996-08-23
CA2168829C (en) 1997-12-16
CA2210022A1 (en) 1996-08-07
MY132529A (en) 2007-10-31
SI21923A (sl) 2006-06-30
CZ297171B6 (cs) 2006-09-13
EP1378508A1 (en) 2004-01-07
LV11618A (lv) 1996-12-20
NO960472D0 (no) 1996-02-05
CH689229A5 (de) 1998-12-31
JP2915338B2 (ja) 1999-07-05
KR100289885B1 (ko) 2001-05-15
TR199600096A2 (tr) 1996-08-21
BE1009112A3 (fr) 1996-11-05
IE960104A1 (en) 1996-08-07
CN1289496C (zh) 2006-12-13
EP1136490B1 (en) 2004-01-07
DE19603797C2 (de) 1998-11-12
NO960472L (no) 1996-08-07
CN1216055C (zh) 2005-08-24
BG62967B1 (bg) 2000-12-29
CZ32096A3 (en) 1996-08-14
CA2210022C (en) 2005-09-13
FI960519A0 (fi) 1996-02-05
DE69621777D1 (de) 2002-07-18
NO20015070L (no) 1996-08-07
AU4332896A (en) 1996-08-15
FR2730232B1 (fr) 1997-08-01
CN1310180A (zh) 2001-08-29
HK59397A (en) 1997-05-16
SE9600406D0 (sv) 1996-02-05
CA2211522C (en) 1999-12-07
SI9600036B (sl) 2006-12-31
PT101827A (pt) 1996-09-30
EP0808314B1 (en) 2002-06-12
SK14396A3 (en) 1996-11-06
PL312646A1 (en) 1996-08-19
ITMI960203A1 (it) 1997-08-05
DK200100223A (fi) 2001-02-12
ES2114471B1 (es) 1999-08-16
NZ280943A (en) 1997-01-29
DE69621777T2 (de) 2003-01-02
CA2210023C (en) 1999-02-09
MX198371B (fi) 2000-08-29
DK11996A (da) 1996-08-07
DZ1989A1 (fr) 2002-10-15

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