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ES8606330A1 - Procedimiento para preparar derivados de acidos quinolincar-boxilicos - Google Patents

Procedimiento para preparar derivados de acidos quinolincar-boxilicos

Info

Publication number
ES8606330A1
ES8606330A1 ES543686A ES543686A ES8606330A1 ES 8606330 A1 ES8606330 A1 ES 8606330A1 ES 543686 A ES543686 A ES 543686A ES 543686 A ES543686 A ES 543686A ES 8606330 A1 ES8606330 A1 ES 8606330A1
Authority
ES
Spain
Prior art keywords
acids
procedure
quinolincar
boxilic
preparing derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES543686A
Other languages
English (en)
Other versions
ES543686A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyorin Pharmaceutical Co Ltd
Original Assignee
Kyorin Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyorin Pharmaceutical Co Ltd filed Critical Kyorin Pharmaceutical Co Ltd
Publication of ES543686A0 publication Critical patent/ES543686A0/es
Publication of ES8606330A1 publication Critical patent/ES8606330A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Quinoline Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR DERIVADOS DE ACIDOS QUINOLINCARBOXILICOS. CONSISTE EN CONDENSAR UN COMPUESTO DE FORMULA (II) CON UNA AMINA SECUNDARIA DE FORMULA (III), TRAS LO CUAL, CUANDO R1 ES UN GRUPO ALQUILO INFERIOR, EL PRODUCTO CONDENSADO PUEDE SAPONIFICARSE, OPCIONALMENTE PARA OBTENER EL ACIDO QUINOLINCARBOXILICO DE FORMULA (I) DONDE R ES UN ATOMO DE H O UN GRUPO METILO. LA REACCION SE EFECTUA CALENTANDO DOS REACTANTES EN UN DISOLVENTE COMO AGUA, ALCOHOLES Y OTROS; EN PRESENCIA DE UN ACEPTOR ACIDO; Y A UNA TEMPERATURA ENTRE LA AMBIENTE Y 200JC. TIENEN APLICACIONES FARMACOLOGICAS PARA SER UTILIZADOS COMO AGENTES ANTIBACTERIANOS.
ES543686A 1985-03-08 1985-05-30 Procedimiento para preparar derivados de acidos quinolincar-boxilicos Expired ES8606330A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP60046216A JPS61205258A (ja) 1985-03-08 1985-03-08 キノロンカルボン酸誘導体及びその製造方法

Publications (2)

Publication Number Publication Date
ES543686A0 ES543686A0 (es) 1986-04-01
ES8606330A1 true ES8606330A1 (es) 1986-04-01

Family

ID=12740905

Family Applications (1)

Application Number Title Priority Date Filing Date
ES543686A Expired ES8606330A1 (es) 1985-03-08 1985-05-30 Procedimiento para preparar derivados de acidos quinolincar-boxilicos

Country Status (16)

Country Link
EP (1) EP0195841A1 (es)
JP (1) JPS61205258A (es)
KR (1) KR860007244A (es)
CN (1) CN1010778B (es)
AU (1) AU4282985A (es)
DK (1) DK241585A (es)
ES (1) ES8606330A1 (es)
FI (1) FI852172L (es)
GR (1) GR851299B (es)
HU (1) HU194865B (es)
MX (1) MX159506A (es)
NO (1) NO852076L (es)
NZ (1) NZ212239A (es)
PH (1) PH20703A (es)
PT (1) PT80546B (es)
ZA (1) ZA853954B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3420743A1 (de) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-6,8-dihalogen-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
US4977154A (en) * 1985-12-12 1990-12-11 Warner-Lambert Company 5-amino and 5-hydroxy-6-fluoroquinolones as antibacterial agents
US4668680A (en) * 1985-12-12 1987-05-26 Warner-Lambert Company 5-amino-6,8-difluoroquinolones as antibacterial agents
DE3705621C2 (de) * 1986-02-25 1997-01-09 Otsuka Pharma Co Ltd Heterocyclisch substituierte Chinoloncarbonsäurederivate
DE3635218A1 (de) * 1986-10-16 1988-04-21 Bayer Ag 7-amino-1-cyclopropyl-8-chlor-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
DE3641312A1 (de) * 1986-12-03 1988-06-09 Bayer Ag Verfahren zur herstellung von chinolincarbonsaeuren
US5563138A (en) * 1987-04-16 1996-10-08 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
US4851418A (en) * 1987-08-21 1989-07-25 Warner-Lambert Company Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent
SK286420B6 (sk) * 1997-09-15 2008-09-05 The Procter & Gamble Company Zlúčenina so štruktúrou chinolónu, farmaceutický prostriedok s jej obsahom a jej použitie
AU2001232238B2 (en) * 2000-02-09 2005-03-24 Daiichi Pharmaceutical Co., Ltd. Anti-acid-fast bacterial agents containing pyridonecarboxylic acids as the active ingredient
PT2001862E (pt) 2006-03-28 2011-07-20 Warner Chilcott Co Llc Sais de malato e polimorfos do ácido (3s,5s)-7-[3- amino-5-metil-piperidinil]-1-ciclopropil-1,4-dihidro- 8-metoxi-4-oxo-3-quinolinocarboxílico
EP1999125A2 (en) 2006-03-28 2008-12-10 The Procter and Gamble Company A coupling process for preparing quinolone intermediates
CN103709100A (zh) * 2013-12-31 2014-04-09 南京工业大学 一种8-氯代喹诺酮衍生物的制备方法
CN114790133B (zh) * 2021-01-26 2024-06-18 江苏中旗科技股份有限公司 一种以2-氯-4-氨基苯腈为原料合成2-氯-4-氟苯甲酸的方法
CN114790139B (zh) * 2021-01-26 2024-06-18 江苏中旗科技股份有限公司 一种以2-氯-4-氨基溴苯为原料合成2-氯-4-氟苯甲酸的方法
CN114716373B (zh) * 2022-04-14 2023-01-10 内蒙古源宏精细化工有限公司 一种加替沙星环合酯的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5630964A (en) * 1979-08-22 1981-03-28 Kyorin Pharmaceut Co Ltd Novel substituted quinolinecarboxylic acid and its preparation
JPS60123837A (ja) * 1983-12-09 1985-07-02 Mitsubishi Paper Mills Ltd ハロゲン化銀写真乳剤
DE3420743A1 (de) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-6,8-dihalogen-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel

Also Published As

Publication number Publication date
FI852172A7 (fi) 1986-09-09
FI852172A0 (fi) 1985-05-30
HUT38337A (en) 1986-05-28
AU4282985A (en) 1986-09-11
DK241585D0 (da) 1985-05-30
CN85104693A (zh) 1986-09-03
DK241585A (da) 1986-09-09
KR860007244A (ko) 1986-10-10
FI852172L (fi) 1986-09-09
PT80546B (en) 1986-12-15
MX159506A (es) 1989-06-21
JPS61205258A (ja) 1986-09-11
NO852076L (no) 1986-09-09
ES543686A0 (es) 1986-04-01
CN1010778B (zh) 1990-12-12
EP0195841A1 (en) 1986-10-01
HU194865B (en) 1988-03-28
NZ212239A (en) 1988-02-12
PT80546A (en) 1985-06-01
PH20703A (en) 1987-03-24
GR851299B (es) 1985-11-25
ZA853954B (en) 1986-01-29

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20041009