ES8605220A1 - Esters of diethylene glycol - Google Patents
Esters of diethylene glycolInfo
- Publication number
- ES8605220A1 ES8605220A1 ES548226A ES548226A ES8605220A1 ES 8605220 A1 ES8605220 A1 ES 8605220A1 ES 548226 A ES548226 A ES 548226A ES 548226 A ES548226 A ES 548226A ES 8605220 A1 ES8605220 A1 ES 8605220A1
- Authority
- ES
- Spain
- Prior art keywords
- esters
- diethylene glycol
- socl2
- pref
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 title abstract 4
- 150000002148 esters Chemical class 0.000 title abstract 2
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 4
- 229910006124 SOCl2 Inorganic materials 0.000 abstract 2
- WLJVXDMOQOGPHL-UHFFFAOYSA-N phenylacetic acid Chemical compound OC(=O)CC1=CC=CC=C1 WLJVXDMOQOGPHL-UHFFFAOYSA-N 0.000 abstract 2
- -1 2-(2-Hydroxyethoxy)ethyl Chemical group 0.000 abstract 1
- IPBVNPXQWQGGJP-UHFFFAOYSA-N acetic acid phenyl ester Natural products CC(=O)OC1=CC=CC=C1 IPBVNPXQWQGGJP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229940049953 phenylacetate Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
Landscapes
- Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Prodn. of esters (I) comprises direct reaction of diethylene glycol (DEG) with an acid of formula (II), or its Na or K salts. n = 0 or 1; R1 = H, Cl or Me; R2 = H, CF3 or Me; R3 = H or Cl. Reaction is pref. in presence of SOCl2 at room temp. to 100 deg. C. 2-(2-Hydroxyethoxy)ethyl 2-(2,6-dichlorophenylamino) phenylacetate (Ia) is a new cpd. - Pref. (II) have (1) R1 = R3 = Cl; R2 = H; n = 1; (2) R1 = R3 = H; R2 = CF3; n = O; (3) R1 = R3 = Cl; R2 = Me; N = O; (4) R1 = R2 = Me; R3 = H; n = O. SOCl2 is used in a stoichiometric, or slightly higher, amt. relative to (II).
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES548226A ES8605220A1 (en) | 1985-10-25 | 1985-10-25 | Esters of diethylene glycol |
| PT81505A PT81505B (en) | 1985-10-25 | 1985-11-15 | PREPARATION PROCESS OF DIETILENO-GLYCOL ESTERS |
| IT21774/86A IT1197255B (en) | 1985-10-25 | 1986-09-19 | DIETHYLENGLYCOL ESTER PREPARATION PROCEDURE |
| CH3810/86A CH676238A5 (en) | 1985-10-25 | 1986-10-22 | |
| DE19863636125 DE3636125A1 (en) | 1985-10-25 | 1986-10-23 | METHOD FOR PRODUCING DIETHYLENE GLYCOLESTERS |
| JP61252159A JPS62106064A (en) | 1985-10-25 | 1986-10-24 | Production of diethylene glycol ester |
| GB8625481A GB2182041B (en) | 1985-10-25 | 1986-10-24 | Preparation of esters of diethylene glycol |
| BE0/217337A BE905666A (en) | 1985-10-25 | 1986-10-27 | PROCESS FOR THE PREPARATION OF DIETHYLENEGLYCOL ESTERS. |
| FR868614922A FR2589151B1 (en) | 1985-10-25 | 1986-10-27 | PROCESS FOR THE PREPARATION OF DIETHYLENEGLYCOL ESTERS |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES548226A ES8605220A1 (en) | 1985-10-25 | 1985-10-25 | Esters of diethylene glycol |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8605220A1 true ES8605220A1 (en) | 1986-03-16 |
| ES548226A0 ES548226A0 (en) | 1986-03-16 |
Family
ID=8490031
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES548226A Expired ES8605220A1 (en) | 1985-10-25 | 1985-10-25 | Esters of diethylene glycol |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS62106064A (en) |
| BE (1) | BE905666A (en) |
| CH (1) | CH676238A5 (en) |
| DE (1) | DE3636125A1 (en) |
| ES (1) | ES8605220A1 (en) |
| FR (1) | FR2589151B1 (en) |
| GB (1) | GB2182041B (en) |
| IT (1) | IT1197255B (en) |
| PT (1) | PT81505B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3811118C1 (en) * | 1988-03-31 | 1989-10-12 | Merckle Gmbh, 7902 Blaubeuren, De | |
| US9217066B2 (en) | 2008-03-31 | 2015-12-22 | Ford Global Technologies, Llc | Structural polymer insert and method of making the same |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1939112C3 (en) * | 1969-08-01 | 1975-03-06 | Troponwerke Dinklage & Co, 5000 Koeln | Esters of N- (3-trifluoromethylphenyl) anthranilic acid, process for their preparation and pharmacologically active preparations thereof |
| DE2735569A1 (en) * | 1977-08-06 | 1979-02-15 | Troponwerke Gmbh & Co Kg | Antiinflammatory and antirheumatic agent prodn. - esp. N-tri:fluoro:methyl-phenyl-anthranilic acid hydroxy-ethoxy-ethyl ester |
| DE2834167C2 (en) * | 1978-08-04 | 1984-01-26 | Troponwerke GmbH & Co KG, 5000 Köln | Process for the preparation of 2- (2-hydroxyethoxy) ethyl-N - (α, α, α-trifluoro-m-tolyl) anthranilate |
| DE2834169C2 (en) * | 1978-08-04 | 1984-02-09 | Troponwerke GmbH & Co KG, 5000 Köln | Process for the preparation of 2- (2-hydroxyethoxy) ethyl-N- (alpha, alpha, alpha -trifluoro-m-tolyl) anthranilate |
| DE2834168C2 (en) * | 1978-08-04 | 1984-02-09 | Troponwerke GmbH & Co KG, 5000 Köln | Process for the preparation of 2- (2-hydroxyethoxy) ethyl-N - (α, α, α-trifluoro-m-tolyl) anthranilate |
| DE2926472A1 (en) * | 1979-06-30 | 1981-01-15 | Thomae Gmbh Dr K | NEW BENZOYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINAL PRODUCTS |
| IL67445A (en) * | 1982-12-09 | 1985-11-29 | Teva Pharma | Ethoxycarbonyloxy ethyl esters of non-steroidal anti-inflammatory carboxylic acids |
| EP0132690B1 (en) * | 1983-07-21 | 1989-02-01 | Troponwerke GmbH & Co. KG | Thermoplastics containing antiphlogistics |
| US4694105A (en) * | 1983-12-20 | 1987-09-15 | Ciba-Geigy Corporation | Herbicidal alkoxyamino- and polyalkoxyaminodiphenyl ethers |
| DE3407507A1 (en) * | 1984-03-01 | 1985-09-05 | A. Nattermann & Cie GmbH, 5000 Köln | Novel o-(2,6-dichloroanilino)phenylacetic acid esters, process for their preparation, and pharmaceutical preparations containing them |
-
1985
- 1985-10-25 ES ES548226A patent/ES8605220A1/en not_active Expired
- 1985-11-15 PT PT81505A patent/PT81505B/en not_active IP Right Cessation
-
1986
- 1986-09-19 IT IT21774/86A patent/IT1197255B/en active
- 1986-10-22 CH CH3810/86A patent/CH676238A5/de not_active IP Right Cessation
- 1986-10-23 DE DE19863636125 patent/DE3636125A1/en not_active Ceased
- 1986-10-24 GB GB8625481A patent/GB2182041B/en not_active Expired
- 1986-10-24 JP JP61252159A patent/JPS62106064A/en active Pending
- 1986-10-27 FR FR868614922A patent/FR2589151B1/en not_active Expired - Lifetime
- 1986-10-27 BE BE0/217337A patent/BE905666A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| GB2182041B (en) | 1989-09-20 |
| FR2589151A1 (en) | 1987-04-30 |
| BE905666A (en) | 1987-02-16 |
| CH676238A5 (en) | 1990-12-28 |
| IT8621774A0 (en) | 1986-09-19 |
| JPS62106064A (en) | 1987-05-16 |
| FR2589151B1 (en) | 1990-05-18 |
| PT81505A (en) | 1985-12-01 |
| DE3636125A1 (en) | 1987-04-30 |
| GB2182041A (en) | 1987-05-07 |
| ES548226A0 (en) | 1986-03-16 |
| GB8625481D0 (en) | 1986-11-26 |
| IT1197255B (en) | 1988-11-30 |
| PT81505B (en) | 1987-11-11 |
| IT8621774A1 (en) | 1988-03-19 |
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