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ES8504179A1 - "procedimiento para preparar derivados de 1,4-dihidropiridina". - Google Patents

"procedimiento para preparar derivados de 1,4-dihidropiridina".

Info

Publication number
ES8504179A1
ES8504179A1 ES523243A ES523243A ES8504179A1 ES 8504179 A1 ES8504179 A1 ES 8504179A1 ES 523243 A ES523243 A ES 523243A ES 523243 A ES523243 A ES 523243A ES 8504179 A1 ES8504179 A1 ES 8504179A1
Authority
ES
Spain
Prior art keywords
preparing
procedure
dihydropyridine derivatives
radical
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES523243A
Other languages
English (en)
Other versions
ES523243A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES8504179A1 publication Critical patent/ES8504179A1/es
Publication of ES523243A0 publication Critical patent/ES523243A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/12—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR DERIVADOS DE 1,4-DIHIDROPIRIDINA, DE FORMULA GENERAL (I), EN LA QUE R1 Y R2 REPRESENTAN METILO, UNO DE ELLOS, Y N-BUTILO O ISOPROPILO, EL OTRO; R3 REPRESENTA HIDROGENO O ALQUILO, Y SUS SALES.CONSISTE EN REEMPLAZAR EL RADICAL R4 ES UN ISOMERO OPTICO DE UN COMPUESTO DE FORMULA (II), POR UN RADICAL: OR2.DE APLICACION EN MEDICINA Y FARMACIA.
ES523243A 1982-06-15 1983-06-14 "procedimiento para preparar derivados de 1,4-dihidropiridina". Granted ES523243A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH369382 1982-06-15
CH369282 1982-06-15

Publications (2)

Publication Number Publication Date
ES8504179A1 true ES8504179A1 (es) 1985-04-01
ES523243A0 ES523243A0 (es) 1985-04-01

Family

ID=25693638

Family Applications (2)

Application Number Title Priority Date Filing Date
ES523243A Granted ES523243A0 (es) 1982-06-15 1983-06-14 "procedimiento para preparar derivados de 1,4-dihidropiridina".
ES538157A Expired ES8604578A1 (es) 1982-06-15 1984-11-30 Procedimiento para preparar derivados de 1,4-dihidropiridina

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES538157A Expired ES8604578A1 (es) 1982-06-15 1984-11-30 Procedimiento para preparar derivados de 1,4-dihidropiridina

Country Status (19)

Country Link
AU (1) AU1575383A (es)
BE (1) BE897000A (es)
CA (1) CA1208639A (es)
CH (1) CH660593A5 (es)
DE (1) DE3320616A1 (es)
DK (1) DK271183A (es)
ES (2) ES523243A0 (es)
FI (1) FI832072L (es)
FR (1) FR2528431B1 (es)
GB (1) GB2122192B (es)
HU (1) HU191853B (es)
IT (1) IT1178353B (es)
NL (1) NL8302067A (es)
NZ (1) NZ204536A (es)
PH (1) PH23436A (es)
PT (1) PT76870B (es)
SE (1) SE8303385L (es)
WO (1) WO1984000033A1 (es)
ZA (1) ZA834409B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3431152A1 (de) * 1984-08-24 1986-03-06 Cassella Ag, 6000 Frankfurt Verfahren zur herstellung optisch aktiver, substituierter 1,4-dihydropyridine und ihre verwendung als arzneimittel
GB8428552D0 (en) * 1984-11-12 1984-12-19 Sandoz Ltd Organic compounds
US5260321A (en) * 1984-11-12 1993-11-09 Sandoz Ltd. Use of 1,4-dihydropyridine derivatives and combinations thereof with calcitonins
DE3447169A1 (de) * 1984-12-22 1986-07-03 Bayer Ag, 5090 Leverkusen Optisch aktive nitrodihydropyridine, verfahren zur herstellung und ihre verwendung in arzneimitteln
US4920225A (en) * 1986-12-22 1990-04-24 Laboratoires Syntex S.A. Resolution of 1,4-dihydropyridine derivatives
EP0353238A1 (de) * 1987-03-27 1990-02-07 Byk Gulden Lomberg Chemische Fabrik Gmbh Neue zwischenprodukte und verfahren
DE4041814A1 (de) * 1990-12-24 1992-07-02 Byk Gulden Lomberg Chem Fab Verfahren zur herstellung von dihydrophyridincarbonsaeuren
US5135936A (en) * 1991-03-05 1992-08-04 Marion Merrell Dow Inc. Isomers of 1-azabicyclo[2.2.2]oct-3-yl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinediacarboxylic and their use as calcium antagonists
CN100425599C (zh) * 2005-12-31 2008-10-15 清华大学 一种有机电致发光材料及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH639659A5 (de) * 1978-12-18 1983-11-30 Sandoz Ag Neue 1,4-dihydropyridinderivate, deren herstellung und verwendung.
FI64938C (fi) * 1977-06-20 1984-02-10 Sandoz Ag Foerfarande foer framstaellning av nya terapeutiskt anvaendbara bensoxa- och bensotiadiazolyl-1,4-dihydropyridinderivat
DE2949464A1 (de) * 1978-12-18 1980-06-26 Sandoz Ag Benzoxadiazole und benzothiadiazole, ihre herstellung und verwendung
FI813460L (fi) * 1980-11-10 1982-05-11 Sandoz Ag Nya 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-pyridinderivat deras framstaellningsfoerfarande och dessa innehaollande farmaceutiska kompositioner

Also Published As

Publication number Publication date
FI832072A7 (fi) 1983-12-16
PH23436A (en) 1989-08-07
NL8302067A (nl) 1984-01-02
IT1178353B (it) 1987-09-09
DK271183D0 (da) 1983-06-13
FR2528431A1 (fr) 1983-12-16
ES538157A0 (es) 1986-02-01
PT76870B (en) 1986-02-27
BE897000A (fr) 1983-12-09
ZA834409B (en) 1985-02-27
PT76870A (en) 1983-07-01
CA1208639A (en) 1986-07-29
SE8303385L (sv) 1983-12-16
CH660593A5 (de) 1987-05-15
DE3320616A1 (de) 1983-12-15
GB2122192A (en) 1984-01-11
SE8303385D0 (sv) 1983-06-14
ES8604578A1 (es) 1986-02-01
DK271183A (da) 1983-12-16
HU191853B (en) 1987-04-28
NZ204536A (en) 1986-09-10
GB8316054D0 (en) 1983-07-20
GB2122192B (en) 1985-12-18
AU1575383A (en) 1983-12-22
WO1984000033A1 (fr) 1984-01-05
FI832072A0 (fi) 1983-06-08
FI832072L (fi) 1983-12-16
FR2528431B1 (fr) 1986-01-10
IT8348488A0 (it) 1983-06-13
ES523243A0 (es) 1985-04-01

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