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ES8300088A1 - Procedimiento para preparar acilamilidas. - Google Patents

Procedimiento para preparar acilamilidas.

Info

Publication number
ES8300088A1
ES8300088A1 ES502441A ES502441A ES8300088A1 ES 8300088 A1 ES8300088 A1 ES 8300088A1 ES 502441 A ES502441 A ES 502441A ES 502441 A ES502441 A ES 502441A ES 8300088 A1 ES8300088 A1 ES 8300088A1
Authority
ES
Spain
Prior art keywords
elevated
preparing
procedure
trifluormethyl
cyan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES502441A
Other languages
English (en)
Other versions
ES502441A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Publication of ES502441A0 publication Critical patent/ES502441A0/es
Publication of ES8300088A1 publication Critical patent/ES8300088A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/44—Two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/56—Unsaturated compounds containing hydroxy or O-metal groups containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Steroid Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR ACILANILIDAS. SE HACE REACCIONAR UNA AMINA DE FORMULA GENERAL (I), CON UN ACIDO (II) PARA DAR COMPUESTO (III). EN LOS COMPUESTOS DE PARTIDA, R ELEVADO, Y R ELEVADO 2 PUEDEN SER IGUALES O DIFERENTES SIENDO CADA UNO CIANO, NITRO, TRIFLUORMETILO O CLORO; R ELEVADO 3 Y R ELEVADO 6 SON AMBOS HIDROGENO, R ELEVADO 5 METILO; R ELEVADO 4 ES ACILOXI Y EL ANILLO A LLEVA UN SUSTITUYENTE EN LA POSICION PARA, EL CUAL ES SUSTITUYENTE MITRO, FLUOR, TRIFLUORMETILO, CIANO, METOXICARBONILO, METILTIO, METILSUFINILO, METANOSULFONILO; EL GRUPO R ELEVADO 5 ESTA HIDROLIZADO A HIDROXI. ACTIVIDAD ANTIANDROGENICA. *FORMULA*.
ES502441A 1980-05-22 1981-05-22 Procedimiento para preparar acilamilidas. Expired ES8300088A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8016915 1980-05-22

Publications (2)

Publication Number Publication Date
ES502441A0 ES502441A0 (es) 1982-10-01
ES8300088A1 true ES8300088A1 (es) 1982-10-01

Family

ID=10513596

Family Applications (2)

Application Number Title Priority Date Filing Date
ES502441A Expired ES8300088A1 (es) 1980-05-22 1981-05-22 Procedimiento para preparar acilamilidas.
ES512702A Granted ES512702A0 (es) 1980-05-22 1982-05-31 Procedimiento para preparar una acilanilida. (como desglose y con prioridad de la patente espanola n 502.411, presentada el 22 de mayo de 1981.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES512702A Granted ES512702A0 (es) 1980-05-22 1982-05-31 Procedimiento para preparar una acilanilida. (como desglose y con prioridad de la patente espanola n 502.411, presentada el 22 de mayo de 1981.

Country Status (19)

Country Link
US (1) US4386080A (es)
EP (1) EP0040932B1 (es)
JP (1) JPS5711951A (es)
AT (1) ATE14115T1 (es)
AU (1) AU543459B2 (es)
CA (1) CA1161850A (es)
DE (1) DE3171196D1 (es)
DK (1) DK219981A (es)
ES (2) ES8300088A1 (es)
FI (1) FI811547L (es)
GR (1) GR75659B (es)
HU (1) HU185799B (es)
IE (1) IE51201B1 (es)
IL (1) IL62873A (es)
NO (1) NO811730L (es)
NZ (1) NZ197008A (es)
PT (1) PT73079B (es)
YU (1) YU130981A (es)
ZA (1) ZA813099B (es)

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GB8617653D0 (en) * 1986-07-18 1986-08-28 Ici Plc Amide derivatives
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Also Published As

Publication number Publication date
YU130981A (en) 1983-10-31
ES502441A0 (es) 1982-10-01
US4386080A (en) 1983-05-31
AU543459B2 (en) 1985-04-18
ZA813099B (en) 1982-05-26
IE811010L (en) 1981-11-22
ES8303285A1 (es) 1983-02-01
CA1161850A (en) 1984-02-07
EP0040932B1 (en) 1985-07-03
PT73079B (en) 1982-07-15
GR75659B (es) 1984-08-02
ES512702A0 (es) 1983-02-01
AU7029581A (en) 1981-11-26
NO811730L (no) 1981-11-23
DK219981A (da) 1981-11-23
NZ197008A (en) 1984-10-19
FI811547A7 (fi) 1981-11-23
EP0040932A1 (en) 1981-12-02
PT73079A (en) 1981-06-01
ATE14115T1 (de) 1985-07-15
JPS5711951A (en) 1982-01-21
IE51201B1 (en) 1986-10-29
HU185799B (en) 1985-03-28
DE3171196D1 (en) 1985-08-08
FI811547L (fi) 1981-11-23
IL62873A (en) 1985-05-31

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