ES8106233A1 - Procedimiento de producir preparaciones de insulina - Google Patents
Procedimiento de producir preparaciones de insulinaInfo
- Publication number
- ES8106233A1 ES8106233A1 ES494790A ES494790A ES8106233A1 ES 8106233 A1 ES8106233 A1 ES 8106233A1 ES 494790 A ES494790 A ES 494790A ES 494790 A ES494790 A ES 494790A ES 8106233 A1 ES8106233 A1 ES 8106233A1
- Authority
- ES
- Spain
- Prior art keywords
- insulin
- insulin preparation
- preparing
- preparation
- injectable insulin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title abstract 14
- 102000004877 Insulin Human genes 0.000 title abstract 7
- 108090001061 Insulin Proteins 0.000 title abstract 7
- 229940125396 insulin Drugs 0.000 title abstract 7
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000306 component Substances 0.000 abstract 1
- 239000012533 medium component Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Dermatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE PREPARACIONES DE INSULINA. CONSISTE EN SOMETER UNA DISOLUCION DE INSULINA A UN PROCESO CROMATOGRAFICO PARA QUE LA INSULINA SE TRANSFIERA A UN ELUYENTE QUE FORMA PARTE DEL MEDIO VEHICULO DE LA PREPARACION DESEADA. DESPUES DE ESTO EL ELUATO FORMADO SE INCORPORA A LOS RESTANTES COMPONENTES DEL MEDIO VEHICULO Y SE AJUSTA A LOS VALORES DESEADOS DE PH Y CONCENTRACION DE INSULINA PARA OBTENER LA PREPARACION ACABADA. DE APLICACION PARA EL TRATAMIENTO DE LA DIABETES.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK374579A DK374579A (da) | 1979-09-07 | 1979-09-07 | Fremgangsmaade til fremstilling af et injucerbart insulinpraeparat |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8106233A1 true ES8106233A1 (es) | 1981-08-16 |
| ES494790A0 ES494790A0 (es) | 1981-08-16 |
Family
ID=8126294
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES494790A Granted ES494790A0 (es) | 1979-09-07 | 1980-09-05 | Procedimiento de producir preparaciones de insulina |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0035026A1 (es) |
| BE (1) | BE885115A (es) |
| DK (1) | DK374579A (es) |
| ES (1) | ES494790A0 (es) |
| FI (1) | FI802756A7 (es) |
| WO (1) | WO1981000674A1 (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2077132A1 (en) | 2008-01-02 | 2009-07-08 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dispensing device, storage device and method for dispensing a formulation |
| US10011906B2 (en) | 2009-03-31 | 2018-07-03 | Beohringer Ingelheim International Gmbh | Method for coating a surface of a component |
| JP5763053B2 (ja) | 2009-05-18 | 2015-08-12 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | アダプタ、吸入器具及びアトマイザ |
| US10016568B2 (en) | 2009-11-25 | 2018-07-10 | Boehringer Ingelheim International Gmbh | Nebulizer |
| EP2504051B1 (en) | 2009-11-25 | 2019-09-04 | Boehringer Ingelheim International GmbH | Nebulizer |
| AP3141A (en) | 2009-11-25 | 2015-02-28 | Boehringer Ingelheim Int | Nebulizer |
| JP5874724B2 (ja) | 2010-06-24 | 2016-03-02 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ネブライザ |
| WO2012130757A1 (de) | 2011-04-01 | 2012-10-04 | Boehringer Ingelheim International Gmbh | Medizinisches gerät mit behälter |
| US9827384B2 (en) | 2011-05-23 | 2017-11-28 | Boehringer Ingelheim International Gmbh | Nebulizer |
| WO2013152894A1 (de) | 2012-04-13 | 2013-10-17 | Boehringer Ingelheim International Gmbh | Zerstäuber mit kodiermitteln |
| ES2836977T3 (es) | 2013-08-09 | 2021-06-28 | Boehringer Ingelheim Int | Nebulizador |
| US9744313B2 (en) | 2013-08-09 | 2017-08-29 | Boehringer Ingelheim International Gmbh | Nebulizer |
| ES2874029T3 (es) | 2014-05-07 | 2021-11-04 | Boehringer Ingelheim Int | Nebulizador |
| CN106255554B (zh) | 2014-05-07 | 2021-05-04 | 勃林格殷格翰国际有限公司 | 容器、喷雾器及用途 |
| PE20210959A1 (es) | 2014-05-07 | 2021-05-25 | Boehringer Ingelheim Int | Nebulizador, dispositivo indicador y recipiente |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1285023A (en) * | 1968-08-09 | 1972-08-09 | Novo Terapeutisk Labor As | Improvements in or relating to injectable insulin preparations |
| US3878186A (en) * | 1973-05-09 | 1975-04-15 | Lilly Co Eli | Process for purifying insulin |
| US3876623A (en) * | 1973-05-09 | 1975-04-08 | Lilly Co Eli | Process for purifying insulin |
| DK140801B (da) * | 1975-01-15 | 1979-11-19 | Nordisk Insulinlab | Fremgangsmåde til fremstilling af et stabilt langtidsvirkende insulinpræparat. |
| NL7713966A (nl) * | 1976-12-27 | 1978-06-29 | Univ Minnesota | Werkwijze voor het behandelen van insuline. |
| AU5397579A (en) * | 1978-12-26 | 1980-07-03 | Eli Lilly And Company | Purifying insulin |
-
1979
- 1979-09-07 DK DK374579A patent/DK374579A/da unknown
-
1980
- 1980-09-01 WO PCT/DK1980/000055 patent/WO1981000674A1/en not_active Ceased
- 1980-09-02 FI FI802756A patent/FI802756A7/fi not_active Application Discontinuation
- 1980-09-05 BE BE0/202010A patent/BE885115A/fr unknown
- 1980-09-05 ES ES494790A patent/ES494790A0/es active Granted
-
1981
- 1981-03-23 EP EP80901761A patent/EP0035026A1/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| BE885115A (fr) | 1981-03-05 |
| DK374579A (da) | 1981-03-08 |
| FI802756A7 (fi) | 1981-01-01 |
| EP0035026A1 (en) | 1981-09-09 |
| ES494790A0 (es) | 1981-08-16 |
| WO1981000674A1 (en) | 1981-03-19 |
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