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ES8106233A1 - A process for preparing an injectable insulin preparation. - Google Patents

A process for preparing an injectable insulin preparation.

Info

Publication number
ES8106233A1
ES8106233A1 ES494790A ES494790A ES8106233A1 ES 8106233 A1 ES8106233 A1 ES 8106233A1 ES 494790 A ES494790 A ES 494790A ES 494790 A ES494790 A ES 494790A ES 8106233 A1 ES8106233 A1 ES 8106233A1
Authority
ES
Spain
Prior art keywords
insulin
insulin preparation
preparing
preparation
injectable insulin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES494790A
Other languages
Spanish (es)
Other versions
ES494790A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nordisk Insulinlaboratorium
Original Assignee
Nordisk Insulinlaboratorium
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nordisk Insulinlaboratorium filed Critical Nordisk Insulinlaboratorium
Publication of ES8106233A1 publication Critical patent/ES8106233A1/en
Publication of ES494790A0 publication Critical patent/ES494790A0/en
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A quick-acting, injectable insulin preparation of low antigenicity is obtained by a chromatographic process during which the insulin is transferred to an eluant consisting of the same carrier medium as forms part of the desired insulin preparation, or one or more components of said carrier medium. The insulin-containing eluate is admixed with any residual medium components and is adjusted to the desired pH and insulin concentration to provide the finished insulin preparation.
ES494790A 1979-09-07 1980-09-05 PROCEDURE FOR PRODUCING INSULIN PREPARATIONS Granted ES494790A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK374579A DK374579A (en) 1979-09-07 1979-09-07 PROCEDURE FOR THE PREPARATION OF AN INJUCABLE INSULIN PREPARATION

Publications (2)

Publication Number Publication Date
ES8106233A1 true ES8106233A1 (en) 1981-08-16
ES494790A0 ES494790A0 (en) 1981-08-16

Family

ID=8126294

Family Applications (1)

Application Number Title Priority Date Filing Date
ES494790A Granted ES494790A0 (en) 1979-09-07 1980-09-05 PROCEDURE FOR PRODUCING INSULIN PREPARATIONS

Country Status (6)

Country Link
EP (1) EP0035026A1 (en)
BE (1) BE885115A (en)
DK (1) DK374579A (en)
ES (1) ES494790A0 (en)
FI (1) FI802756A7 (en)
WO (1) WO1981000674A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
US10011906B2 (en) 2009-03-31 2018-07-03 Beohringer Ingelheim International Gmbh Method for coating a surface of a component
US9265910B2 (en) 2009-05-18 2016-02-23 Boehringer Ingelheim International Gmbh Adapter, inhalation device, and nebulizer
WO2011064163A1 (en) 2009-11-25 2011-06-03 Boehringer Ingelheim International Gmbh Nebulizer
AP3141A (en) 2009-11-25 2015-02-28 Boehringer Ingelheim Int Nebulizer
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
US9943654B2 (en) 2010-06-24 2018-04-17 Boehringer Ingelheim International Gmbh Nebulizer
WO2012130757A1 (en) 2011-04-01 2012-10-04 Boehringer Ingelheim International Gmbh Medical device comprising a container
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
WO2013152894A1 (en) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Atomiser with coding means
EP2835146B1 (en) 2013-08-09 2020-09-30 Boehringer Ingelheim International GmbH Nebulizer
JP6643231B2 (en) 2013-08-09 2020-02-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Nebulizer
CN106456913B (en) 2014-05-07 2019-08-30 勃林格殷格翰国际有限公司 Sprayers and Containers
DK3139979T3 (en) 2014-05-07 2023-10-09 Boehringer Ingelheim Int DEVICE, ATOMIZER AND PROCEDURE
EP3139984B1 (en) 2014-05-07 2021-04-28 Boehringer Ingelheim International GmbH Nebulizer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1285023A (en) * 1968-08-09 1972-08-09 Novo Terapeutisk Labor As Improvements in or relating to injectable insulin preparations
US3878186A (en) * 1973-05-09 1975-04-15 Lilly Co Eli Process for purifying insulin
US3876623A (en) * 1973-05-09 1975-04-08 Lilly Co Eli Process for purifying insulin
DK140801B (en) * 1975-01-15 1979-11-19 Nordisk Insulinlab Process for the preparation of a stable long-acting insulin preparation.
NL7713966A (en) * 1976-12-27 1978-06-29 Univ Minnesota METHOD OF TREATING INSULIN.
AU5397579A (en) * 1978-12-26 1980-07-03 Eli Lilly And Company Purifying insulin

Also Published As

Publication number Publication date
WO1981000674A1 (en) 1981-03-19
BE885115A (en) 1981-03-05
DK374579A (en) 1981-03-08
EP0035026A1 (en) 1981-09-09
FI802756A7 (en) 1981-01-01
ES494790A0 (en) 1981-08-16

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