ES553306A0 - Un metodo para preparar estano mesoporfirina. - Google Patents

Un metodo para preparar estano mesoporfirina.

Info

Publication number: ES553306A0
Authority: ES; Spain
Prior art keywords: mammals; heme; stanon; mesoporphyrine; preparing
Prior art date: 1985-03-25
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES553306A

Other languages

English (en)

Other versions

ES8800670A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Rockefeller University

Original Assignee

Rockefeller University

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-03-25

Filing date

1986-03-24

Publication date

1987-11-16

1986-03-24 Application filed by Rockefeller University filed Critical Rockefeller University

1987-11-16 Publication of ES8800670A1 publication Critical patent/ES8800670A1/es

1987-11-16 Publication of ES553306A0 publication Critical patent/ES553306A0/es

Status Expired legal-status Critical Current

Links

241000124008 Mammalia Species 0.000 abstract 3
150000003278 haem Chemical class 0.000 abstract 3
LLDZJTIZVZFNCM-UHFFFAOYSA-J 3-[18-(2-carboxyethyl)-8,13-diethyl-3,7,12,17-tetramethylporphyrin-21,24-diid-2-yl]propanoic acid;dichlorotin(2+) Chemical compound [H+].[H+].[Cl-].[Cl-].[Sn+4].[N-]1C(C=C2C(=C(C)C(=CC=3C(=C(C)C(=C4)N=3)CC)[N-]2)CCC([O-])=O)=C(CCC([O-])=O)C(C)=C1C=C1C(C)=C(CC)C4=N1 LLDZJTIZVZFNCM-UHFFFAOYSA-J 0.000 abstract 2
230000000694 effects Effects 0.000 abstract 2
230000004060 metabolic process Effects 0.000 abstract 2
QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 abstract 1
QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 abstract 1
208000027119 bilirubin metabolic disease Diseases 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000002440 hepatic effect Effects 0.000 abstract 1
208000036796 hyperbilirubinemia Diseases 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Hematology (AREA)
Diabetes (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Obesity (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Epoxy Resins (AREA)
Compositions Of Macromolecular Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

ES553306A 1985-03-25 1986-03-24 Un metodo para preparar estano mesoporfirina. Expired ES8800670A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/715,515 US4657902A (en)	1985-03-25	1985-03-25	Therapeutic use of tin mesoporphyrin

Publications (2)

Publication Number	Publication Date
ES8800670A1 ES8800670A1 (es)	1987-11-16
ES553306A0 true ES553306A0 (es)	1987-11-16

Family

ID=24874343

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES553306A Expired ES8800670A1 (es)	1985-03-25	1986-03-24	Un metodo para preparar estano mesoporfirina.

Country Status (15)

Country	Link
US (1)	US4657902A (es)
EP (1)	EP0196079B1 (es)
JP (1)	JPS62500787A (es)
KR (1)	KR870700341A (es)
AT (1)	ATE61221T1 (es)
AU (1)	AU567041B2 (es)
CA (1)	CA1293504C (es)
DE (1)	DE3677804D1 (es)
DK (1)	DK162716C (es)
ES (1)	ES8800670A1 (es)
GR (1)	GR860768B (es)
IE (1)	IE58532B1 (es)
PH (2)	PH23102A (es)
WO (1)	WO1986005685A1 (es)
ZA (1)	ZA861793B (es)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4657902A (en) *	1985-03-25	1987-04-14	The Rockefeller University	Therapeutic use of tin mesoporphyrin
KR910009202B1 (ko) *	1985-10-23	1991-11-04	니혼메디피직스 가부시끼가이샤	포르피린 유도체의 제조방법
EP0249966A1 (en) *	1986-06-20	1987-12-23	The Rockefeller University	Tin diiododeuteroporphyrin, its preparation and use, and pharmaceutical compositions thereof
US4782049A (en) *	1986-12-08	1988-11-01	The Rockefeller University	Tin protoporphyrin and tin mesoporphyrin in the treatment of psoriasis
US4831024A (en) *	1987-10-15	1989-05-16	The Board Of Trustees Of The Leland Stanford Junior University	Method to prevent neonatal jaundice
US4997828A (en) *	1989-02-14	1991-03-05	The Rockefeller University	Method of weight control by low level administration of cobalt protoporphyrin or cobalt mesoporphyrin
AU634307B2 (en) *	1989-09-25	1993-02-18	Rockefeller University, The	Orally administered porphyrins to control intestinal iron absorption
US5010073A (en) *	1989-10-05	1991-04-23	The Rockefeller University	Use of liposomes as carriers for metalloporphyrins
US5192757A (en) *	1990-12-20	1993-03-09	Glaxo Inc.	Cobalt porphyrins
US5149697A (en) *	1991-04-18	1992-09-22	Glaxo Inc.	Cobalt porphyrin pharmaceutical compositions
FR2676738B1 (fr) *	1991-05-22	1995-05-05	Ir2M	Nouveau derive organique de metal de transition a structure porphyrinique, composition therapeutique le contenant, en particulier a activite hypoglycemiante.
US5599924A (en) *	1992-08-14	1997-02-04	Trustees Of The University Of Pennsylvania	Electron-deficient porphyrins and processes and intermediates for preparing same
US5817830A (en) *	1992-08-14	1998-10-06	Trustees Of The University Of Pennsylvania	Pyrrolic compounds
US5493017A (en) *	1992-08-14	1996-02-20	The Trustees Of The University Of Pennsylvania	Ring-metalated porphyrins
US5371199B1 (en) *	1992-08-14	1995-12-26	Univ Pennsylvania	Substituted porphyrins porphyrin-containing polymers and synthetic methods therefor
AU7103594A (en) *	1993-06-14	1995-01-03	Rockefeller University, The	Treatment of neonatal hyperbilirubin with metalloporphyrin
US6127356A (en)	1993-10-15	2000-10-03	Duke University	Oxidant scavengers
FI100454B (fi) *	1995-01-30	1997-12-15	Leiras Oy	Hemi-tuotteiden uusi lääkinnällinen käyttö
WO1997005152A1 (en) *	1995-08-02	1997-02-13	Warner-Lambert Company	Amino acid complexes of cobalt (iii) mesoporphyrin ix and cobalt (iii) protoporphyrin ix
CA2309154C (en)	1997-11-03	2010-02-16	Duke University	Substituted porphyrins
CN1093541C (zh) *	1998-01-19	2002-10-30	徐濂	金属卟啉及其生产工艺
ES2163951B1 (es)	1998-07-29	2003-05-16	Airbus Espana Sl	Un sistema de proteccion contra descargas electricas, especialmente rayos, de componentes estructurales de aviones.
ES2162718A1 (es)	1998-07-29	2002-01-01	Const Aeronauticas Sa	Un sistema de proteccion contra descargas electricas, especialmente rayos, de componentes estructurales de aviones.
WO2000018374A1 (en) *	1998-10-01	2000-04-06	Elan Pharma International, Ltd.	Controlled release nanoparticulate compositions
ATE552260T1 (de) *	1999-01-25	2012-04-15	Nat Jewish Health	Substituierte porphyrine und deren therapeutische verwendung
ATE439134T1 (de) *	2001-01-19	2009-08-15	Nat Jewish Med & Res Center	Medikament zum schutz in der radiotherapie
GB0111872D0 (en) *	2001-05-15	2001-07-04	Northwick Park Inst For Medica	Therapeutic agents and methods
AU2002312194B8 (en) *	2001-06-01	2008-05-15	Aeolus Sciences, Inc.	Oxidant scavengers for treatment of diabetes or use in transplantation or induction of immune tolerance
US20080026984A1 (en) *	2002-02-04	2008-01-31	Alfama - Investigacao E Desenvolvimento De Productos Farmaceuticos Lda	Methods for treating inflammatory disease by administering aldehydes and derivatives thereof
JP2005519928A (ja)	2002-02-04	2005-07-07	ハース，ベルナー	Ｃｏ放出能力を有する化合物の投与によって哺乳動物を治療する方法と、ｃｏ放出能力を有する化合物ならびにその医薬組成物
US7968605B2 (en) *	2002-02-04	2011-06-28	ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda.	Methods for treating inflammatory disease by administering aldehydes and derivatives thereof
US6818763B2 (en)	2002-06-04	2004-11-16	Wellspring Pharmaceutical Corporation	Preparation of metal mesoporphyrin halide compounds
US7375216B2 (en) *	2002-06-04	2008-05-20	Infacare Pharmaceutical Corporation	Preparation of metal mesoporphyrin compounds
EP1513537A4 (en) *	2002-06-07	2006-09-06	Univ Duke	Substituted porphyrins
US20040097481A1 (en) *	2002-11-20	2004-05-20	Benjamin Levinson	Water-soluble mesoporphyrin compounds and methods of preparation
GB2395432B (en) *	2002-11-20	2005-09-14	Northwick Park Inst For Medica	Therapeutic delivery of carbon monoxide to extracorporeal and isolated organs
US20070207217A1 (en) *	2003-02-03	2007-09-06	Alfama - Investigacao E Desenvolvimento De Productos Farmaceuticos Lda	Method for treating a mammal by administration of a compound having the ability to release CO
US7008937B2 (en) *	2003-06-10	2006-03-07	Frontier Scientific, Inc.	Porphyrins and metalloporphyrins for inhibiting heme iron uptake
AU2006232330A1 (en) *	2005-04-01	2006-10-12	Infacare Pharmaceutical Corporation	Stannsoporfin compositions and administration
US20060222668A1 (en) *	2005-04-01	2006-10-05	Wellspring Pharmaceutical Corporation	Stannsoporfin compositions, drug products and methods of manufacture
GB0601394D0 (en)	2006-01-24	2006-03-01	Hemocorm Ltd	Therapeutic delivery of carbon monoxide
EA019864B1 (ru)	2006-10-04	2014-06-30	Инфакэар Фармасьютикал Корпорейшн	Крупномасштабное производство станнсопорфина высокой чистоты
EP2732817B1 (en)	2008-05-23	2016-08-24	National Jewish Health	A compound for use in treating injury associated with exposure to phosgene or chlorine gas
EP2691398B1 (en)	2011-03-30	2016-09-28	InfaCare Pharmaceutical Corporation	Methods for synthesizing metal mesoporphyrins
PT2699242T (pt)	2011-04-19	2018-01-22	Alfama Inc	Moléculas de libertação de monóxido de carbono e utilizações das mesmas
ES2628634T3 (es)	2011-07-21	2017-08-03	Alfama, Inc.	Moléculas liberadoras de monóxido de carbono-rutenio y usos de las mismas
GB201120860D0 (en)	2011-12-05	2012-01-18	Cambridge Entpr Ltd	Cancer immunotherapy
HRP20240229T1 (hr)	2014-09-29	2024-04-26	Fred Hutchinson Cancer Center	Sastavi, kompleti i postupci za izazivanje stečene stanične otpornosti pomoću induktora proteina stresa
EP3319613B1 (en)	2015-07-07	2023-02-22	The Research Foundation for The State University of New York	Use of amine carboxyboranes as therapeutic delivery of carbon monoxide and as general drug delivery system in the presence of reactive oxygen species
CN111603472A (zh) *	2020-06-09	2020-09-01	上海市闵行区中心医院	一种锡-中卟啉与青蒿素联合应用在制备抗肿瘤药物中的用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3579533A (en) *	1968-03-18	1971-05-18	Antioch College	Preparation of porphin,substituted porphin and metal chelates thereof
US3687863A (en) *	1970-05-25	1972-08-29	Gen Telephone & Elect	Optical filters containing tetraphenyl-porphins and method of making same
US4393071A (en) *	1975-03-17	1983-07-12	Naoharu Fujii	Method of treating gastric, mammary, lung and uterus tumors
JPS53109929A (en) *	1977-03-04	1978-09-26	Nippon Oil Co Ltd	Medicin for malignant tumor
CA1176978A (en) *	1981-07-15	1984-10-30	Attallah Kappas	Method of controlling of heme metabolism
EP0127797B1 (de) *	1983-06-03	1987-06-16	F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft	Markermoleküle für Fluoreszenz-Immuno-Assays sowie Verfahren und Zwischenprodukte zu deren Herstellung
US4657902A (en) *	1985-03-25	1987-04-14	The Rockefeller University	Therapeutic use of tin mesoporphyrin

1985
- 1985-03-25 US US06/715,515 patent/US4657902A/en not_active Expired - Lifetime
1986
- 1986-02-28 WO PCT/US1986/000445 patent/WO1986005685A1/en not_active Ceased
- 1986-02-28 AU AU55495/86A patent/AU567041B2/en not_active Expired
- 1986-02-28 JP JP61501642A patent/JPS62500787A/ja active Granted
- 1986-03-11 ZA ZA861793A patent/ZA861793B/xx unknown
- 1986-03-20 PH PH33560A patent/PH23102A/en unknown
- 1986-03-21 GR GR860768A patent/GR860768B/el unknown
- 1986-03-24 IE IE75186A patent/IE58532B1/en not_active IP Right Cessation
- 1986-03-24 ES ES553306A patent/ES8800670A1/es not_active Expired
- 1986-03-25 CA CA000505076A patent/CA1293504C/en not_active Expired - Lifetime
- 1986-03-25 AT AT86104120T patent/ATE61221T1/de not_active IP Right Cessation
- 1986-03-25 EP EP86104120A patent/EP0196079B1/en not_active Expired - Lifetime
- 1986-03-25 DE DE8686104120T patent/DE3677804D1/de not_active Expired - Lifetime
- 1986-11-24 KR KR860700831A patent/KR870700341A/ko not_active Ceased
- 1986-11-25 DK DK565786A patent/DK162716C/da not_active IP Right Cessation
1988
- 1988-04-22 PH PH36831A patent/PH24689A/en unknown

Also Published As

Publication number	Publication date
GR860768B (en)	1986-07-22
KR870700341A (ko)	1987-12-28
IE58532B1 (en)	1993-10-06
IE860751L (en)	1986-09-25
ZA861793B (en)	1986-10-29
AU567041B2 (en)	1987-11-05
CA1293504C (en)	1991-12-24
ATE61221T1 (de)	1991-03-15
ES8800670A1 (es)	1987-11-16
WO1986005685A1 (en)	1986-10-09
DE3677804D1 (de)	1991-04-11
DK565786D0 (da)	1986-11-25
JPH0317806B2 (es)	1991-03-11
DK565786A (da)	1986-11-25
US4657902A (en)	1987-04-14
AU5549586A (en)	1986-10-23
EP0196079B1 (en)	1991-03-06
PH24689A (en)	1990-09-07
PH23102A (en)	1989-04-10
EP0196079A1 (en)	1986-10-01
JPS62500787A (ja)	1987-04-02
DK162716C (da)	1992-05-11
DK162716B (da)	1991-12-02

Publication	Publication Date	Title
ES553306A0 (es)	1987-11-16	Un metodo para preparar estano mesoporfirina.
ES8800945A1 (es)	1987-12-01	Un procedimiento para preparar derivados de 8-fenilxantina
ATE81858T1 (de)	1992-11-15	6-thioxanthinderivate.
ES2001978A6 (es)	1988-07-01	Un procedimiento nuevo para la preparacion de analogos de 7-amino-mitosano
ES2002083A6 (es)	1988-07-01	Un metodo para preparar derivados de piroglutamida
MY102071A (en)	1992-03-31	Pyrroloindole derivatives.
ES8707924A1 (es)	1987-09-01	Procedimiento de obtencion de una composicion alimenticia para animales
ES8506000A1 (es)	1985-06-16	Procedimiento para la preparacion de nuevos derivados de triazol dotado de actividad antifungica.
AR241072A2 (es)	1991-10-31	Novedoso catalizador de alquilacion de isoparafinas, para combustibles de motores, con agentes que actuan como olefinas
ES8707496A1 (es)	1987-08-01	Un procedimiento para preparar derivados de azetidinona
NZ216447A (en)	1988-09-29	Wood treating composition based on a copper salt
DE3368199D1 (en)	1987-01-22	Mixture comprising a central analgesic and vitamin b12, or one of its analogs, as active principles
EP0008540A3 (en)	1980-04-02	Method and composition for controlling ectoparasitic acarina
PH23530A (en)	1989-08-25	Mercaptoimidazole derivatives as dopamine-hydroxylase inhibitors
ATE87477T1 (de)	1993-04-15	Chromoglycinsaeure-natriumsalz enthaltende aerosolzubereitungen.
ES8301230A1 (es)	1982-12-01	Un procedimiento para la preparacion de 1-fenil-5-amidotetrazoles.
ES8307204A1 (es)	1983-06-16	"un procedimiento para la preparacion de una difenilamina".
DE3680051D1 (de)	1991-08-08	Ethanolaminderivaten zum verabreichen an vieh.
IT8520065A0 (it)	1985-03-25	Composizioni antistress conattivita' biostimolante per piante.

Legal Events

Date	Code	Title	Description
2008-04-16	FD1A	Patent lapsed	Effective date: 20060909