ES499238A0 - A PROCEDURE FOR THE PREPARATION OF HUMAN INSULIN OR INSULIN ESTERS. - Google Patents

A PROCEDURE FOR THE PREPARATION OF HUMAN INSULIN OR INSULIN ESTERS.

Info

Publication number: ES499238A0
Authority: ES; Spain
Prior art keywords: insulin; procedure; preparation; esters; human
Prior art date: 1980-02-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES499238A

Other languages

Spanish (es)

Other versions

ES8205858A1 (en

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Novo Nordisk AS

Original Assignee

Novo Industri AS

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-02-11

Filing date

1981-02-09

Publication date

1982-08-01

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8095095&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES499238(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1981-02-09 Application filed by Novo Industri AS filed Critical Novo Industri AS

1982-08-01 Publication of ES499238A0 publication Critical patent/ES499238A0/en

1982-08-01 Publication of ES8205858A1 publication Critical patent/ES8205858A1/en

Status Expired legal-status Critical Current

Links

101000976075 Homo sapiens Insulin Proteins 0.000 title 1
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical class N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title 1
PBGKTOXHQIOBKM-FHFVDXKLSA-N insulin (human) Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1CSSC[C@H]2C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=3C=CC(O)=CC=3)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=3NC=NC=3)NC(=O)[C@H](CO)NC(=O)CNC1=O)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O)=O)CSSC[C@@H](C(N2)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)CN)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)CC=1C=CC=CC=1)C(C)C)C1=CN=CN1 PBGKTOXHQIOBKM-FHFVDXKLSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Gastroenterology & Hepatology (AREA)
Endocrinology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Toxicology (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Diabetes (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Forklifts And Lifting Vehicles (AREA)

ES499238A 1980-02-11 1981-02-09 Process for Preparing Insulin Esters Expired ES8205858A1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DK57480A DK147109C (en)	1980-02-11	1980-02-11	METHOD FOR PREPARING HUMAN INSULIN OR HUMAN INSULINESTERS OR A SALT OR COMPLEX THEREOF

Publications (2)

Publication Number	Publication Date
ES499238A0 true ES499238A0 (en)	1982-08-01
ES8205858A1 ES8205858A1 (en)	1982-08-01

Family

ID=8095095

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES499238A Expired ES8205858A1 (en)	1980-02-11	1981-02-09	Process for Preparing Insulin Esters

Country Status (19)

Country	Link
JP (1)	JPS56135452A (en)
AR (1)	AR231277A1 (en)
AU (1)	AU541528B2 (en)
BE (1)	BE887480A (en)
CA (1)	CA1162868A (en)
CH (1)	CH655949A5 (en)
DE (1)	DE3104949C2 (en)
DK (3)	DK147109C (en)
ES (1)	ES8205858A1 (en)
FI (1)	FI77876C (en)
GB (1)	GB2069502B (en)
GR (1)	GR73844B (en)
IT (1)	IT1195038B (en)
NL (1)	NL178797C (en)
NO (1)	NO156247C (en)
NZ (1)	NZ196224A (en)
PT (1)	PT72485B (en)
SE (2)	SE427025B (en)
ZA (1)	ZA81898B (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK147437A (en)	1980-02-11	1900-01-01		Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
DE3101382A1 (en) *	1981-01-17	1982-09-02	Hoechst Ag, 6000 Frankfurt	"METHOD FOR PRODUCING HUMANISULIN OR ITS DERIVATIVES FROM PIG INSULIN OR ITS DERIVATIVES"
EP0088117B1 (en) *	1981-09-15	1986-09-24	Nordisk Insulinlaboratorium	Process for preparing human insulin or b-30 esters thereof
DK149824C (en) *	1982-01-22	1987-03-16	Carlsberg Biotechnology Ltd	PROCEDURE FOR ENZYMATIC REPLACEMENT OF B-30 AMINO ACIDS IN INSULINES
WO1983002772A1 (en) *	1982-02-08	1983-08-18	Robin Ewart Offord	An improved method for preparing human insulin from non-human insulin
DE3209184A1 (en) *	1982-03-13	1983-09-15	Hoechst Ag, 6230 Frankfurt	METHOD FOR CONVERTING PRAEPROINSULIN ANALOGS TO INSULINES
NL8201650A (en) *	1982-04-21	1983-11-16	Akzo Nv	SEMISYNTHETIC PREPARATION OF HUMANE INSULIN.
DE3381980D1 (en) *	1982-04-23	1990-12-13	Wako Pure Chem Ind Ltd	METHOD FOR THE SEMI-SYNTHESIS OF HUMAN INSULIN AND ALKALINE PROTEASE TO BE USED FOR THIS.
DK55183D0 (en) *	1983-02-09	1983-02-09	Nordisk Insulinlab	METHOD OF MANUFACTURING HUMAN INSULIN
DE3334407A1 (en) *	1983-09-23	1985-04-04	Hoechst Ag, 6230 Frankfurt	INSULINE DERIVATIVES MODIFIED IN POSITION B 30, METHOD FOR THE PRODUCTION AND USE THEREOF AND PHARMACEUTICAL AGENTS FOR THE TREATMENT OF THE DIABETES MELLITUS
US5157021A (en) *	1985-03-15	1992-10-20	Novo Nordisk A/S	Insulin derivatives and pharmaceutical preparations containing these derivatives
DK119785D0 (en) *	1985-03-15	1985-03-15	Nordisk Gentofte	INSULIN PREPARATION
SE449472B (en) *	1985-10-15	1987-05-04	Mth Gruppen Ab	EQUIPMENT AT FLOOR STORES
AU612141B2 (en) *	1987-02-25	1991-07-04	Novo Nordisk A/S	Novel insulin derivatives
DK134189D0 (en) *	1989-03-20	1989-03-20	Nordisk Gentofte	INSULIN COMPOUNDS
FI96503C (en) *	1994-08-26	1996-07-10	Hymatic Ltd Oy	Method and apparatus for controlling a mast
AU2005209199B2 (en)	2004-01-16	2008-09-11	Biodel Inc.	Sublingual drug delivery device
US20080090753A1 (en)	2004-03-12	2008-04-17	Biodel, Inc.	Rapid Acting Injectable Insulin Compositions
US7713929B2 (en)	2006-04-12	2010-05-11	Biodel Inc.	Rapid acting and long acting insulin combination formulations
US8084420B2 (en)	2005-09-29	2011-12-27	Biodel Inc.	Rapid acting and long acting insulin combination formulations
CA2649109A1 (en)	2006-04-12	2007-10-25	Biodel, Inc.	Rapid acting and long acting insulin combination formulations
US9060927B2 (en)	2009-03-03	2015-06-23	Biodel Inc.	Insulin formulations for rapid uptake

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK146482C (en) *	1979-04-13	1986-10-06	Shionogi & Co	METHOD FOR PREPARING A B30-THREONINE INSULIN
DK147437A (en)	1980-02-11	1900-01-01		Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
DE3101382A1 (en) *	1981-01-17	1982-09-02	Hoechst Ag, 6000 Frankfurt	"METHOD FOR PRODUCING HUMANISULIN OR ITS DERIVATIVES FROM PIG INSULIN OR ITS DERIVATIVES"

0
- DK DK147437D patent/DK147437A/en unknown
1980
- 1980-02-11 DK DK57480A patent/DK147109C/en not_active IP Right Cessation
1981
- 1981-02-09 DK DK54081A patent/DK147437C/en not_active IP Right Cessation
- 1981-02-09 ES ES499238A patent/ES8205858A1/en not_active Expired
- 1981-02-10 AR AR284258A patent/AR231277A1/en active
- 1981-02-10 SE SE8100926A patent/SE427025B/en not_active IP Right Cessation
- 1981-02-10 IT IT19620/81A patent/IT1195038B/en active
- 1981-02-10 NO NO810443A patent/NO156247C/en unknown
- 1981-02-10 FI FI810385A patent/FI77876C/en not_active IP Right Cessation
- 1981-02-10 GB GB8104114A patent/GB2069502B/en not_active Expired
- 1981-02-10 CA CA000370483A patent/CA1162868A/en not_active Expired
- 1981-02-10 NZ NZ196224A patent/NZ196224A/en unknown
- 1981-02-10 NL NLAANVRAGE8100624,A patent/NL178797C/en not_active IP Right Cessation
- 1981-02-10 JP JP1758081A patent/JPS56135452A/en active Granted
- 1981-02-10 SE SE8100928A patent/SE451143B/en not_active IP Right Cessation
- 1981-02-10 PT PT72485A patent/PT72485B/en not_active IP Right Cessation
- 1981-02-11 BE BE6/47396A patent/BE887480A/en not_active IP Right Cessation
- 1981-02-11 GR GR64097A patent/GR73844B/el unknown
- 1981-02-11 ZA ZA00810898A patent/ZA81898B/en unknown
- 1981-02-11 CH CH910/81A patent/CH655949A5/en not_active IP Right Cessation
- 1981-02-11 AU AU67180/81A patent/AU541528B2/en not_active Ceased
- 1981-02-11 DE DE3104949A patent/DE3104949C2/en not_active Expired

Also Published As

Publication number	Publication date
CA1162868A (en)	1984-02-28
AR231277A1 (en)	1984-10-31
NO156247C (en)	1987-08-19
DK147109B (en)	1984-04-09
DK147437B (en)	1984-08-06
SE8100926L (en)	1982-08-11
IT1195038B (en)	1988-09-28
FI810385L (en)	1981-08-12
PT72485A (en)	1981-03-01
NL8100624A (en)	1981-09-01
ZA81898B (en)	1982-03-31
FI77876C (en)	1989-05-10
DK147109C (en)	1986-12-08
GR73844B (en)	1984-05-07
NO156247B (en)	1987-05-11
BE887480A (en)	1981-08-11
AU6718081A (en)	1981-08-20
JPS56135452A (en)	1981-10-22
NL178797C (en)	1986-05-16
IT8119620A1 (en)	1982-08-10
DE3104949A1 (en)	1981-11-26
SE427025B (en)	1983-02-28
DK147437C (en)	1986-12-08
SE8100928L (en)	1981-08-12
DK54081A (en)	1981-08-12
GB2069502B (en)	1984-08-08
DE3104949C2 (en)	1984-04-26
AU541528B2 (en)	1985-01-10
NZ196224A (en)	1984-08-24
GB2069502A (en)	1981-08-26
NO810443L (en)	1981-08-12
IT8119620A0 (en)	1981-02-10
PT72485B (en)	1982-10-14
NL178797B (en)	1985-12-16
SE451143B (en)	1987-09-07
FI77876B (en)	1989-01-31
DK147437A (en)	1900-01-01
ES8205858A1 (en)	1982-08-01
DK57480A (en)	1981-08-12
CH655949A5 (en)	1986-05-30
JPH0211240B2 (en)	1990-03-13

Publication	Publication Date	Title
ES499238A0 (en)	1982-08-01	A PROCEDURE FOR THE PREPARATION OF HUMAN INSULIN OR INSULIN ESTERS.
ES513604A0 (en)	1983-08-01	A PROCEDURE FOR THE PREPARATION OF A LIVING POLYMER.
ES506969A0 (en)	1983-07-01	A PROCEDURE FOR THE PREPARATION OF PIRIMIDINAS SUBSTITUTES-IDAS.
ES501645A0 (en)	1983-02-01	A PROCEDURE FOR THE PREPARATION OF 6-ALQUILIDEN-PENAMAS.
ES504291A0 (en)	1983-01-01	A PROCEDURE FOR THE PREPARATION OF BENZOTIO-EN AND BENZOFURANSULFONAMIDAS.
ES502200A0 (en)	1982-08-16	A PROCEDURE FOR THE PREPARATION OF HEPARIN ESTERS.
ES505464A0 (en)	1983-01-01	A PROCEDURE FOR THE PREPARATION OF N-HETEROCICLILAMINOCARBONIL ARILSULFONAMIDAS.
ES506141A0 (en)	1982-12-16	A PROCEDURE FOR THE PREPARATION OF PYRIDIN- AND PYRA- CIN-DERIVATIVES
ES515158A0 (en)	1983-06-01	A PROCEDURE FOR THE PREPARATION OF 2-GUANIDINO-4-HETEROARILTIAZOLES.
ES507501A0 (en)	1982-09-01	A PROCEDURE FOR THE PREPARATION OF IMIDAZOLYLPHENYLAMIDINES.
ES503568A0 (en)	1982-11-16	A PROCEDURE FOR THE SYNTHESIS OF HUMAN INSULIN
ES501021A0 (en)	1982-06-01	A PROCEDURE FOR THE PREPARATION OF SILILALKYL ESTERS.
ES513522A0 (en)	1983-03-01	"A PROCEDURE FOR OBTAINING HUMAN INSULIN".
ES507755A0 (en)	1983-02-01	A PROCEDURE FOR THE PREPARATION OF A 2-PIRIDINCARBOXAMIDE DERIVATIVE.
ES507918A0 (en)	1983-04-01	A PROCEDURE FOR THE PREPARATION OF SUBSTITUTED BENZAMITES.
ES503565A0 (en)	1982-05-16	A PROCEDURE FOR THE PREPARATION OF TILACTONE OR A STERDERIVE OF THE SAME
ES507919A0 (en)	1983-01-16	A PROCEDURE FOR THE PREPARATION OF ANTIALERGIC BENZOPYRANOTRIAZOLES.
ES514336A0 (en)	1983-04-16	A PROCEDURE FOR THE PREPARATION OF GUANIDINAS.
ES501232A0 (en)	1982-09-16	A PROCEDURE FOR THE PREPARATION OF PHENYL-QUINOLICIDINS
ES505552A0 (en)	1983-06-01	A PROCEDURE FOR THE PREPARATION OF 1H- OR 2H-TETRAZOLE-5-TIOL
ES506034A0 (en)	1983-01-01	A PROCEDURE FOR THE PREPARATION OF N-CARBOXIALKYL-DIPEPTIDES.
ES506474A0 (en)	1983-02-01	A PROCEDURE FOR THE PREPARATION OF SUBSTITUTED CARBAPENEMAS.
ES501534A0 (en)	1982-08-16	A PROCEDURE FOR THE PREPARATION OF BIS-HYDROXYBENCIL DERIVATIVE.
ES504320A0 (en)	1982-12-16	A PROCEDURE FOR THE PREPARATION OF S-SUBSTITUTED DIALUPIL ACIDS.
ES500254A0 (en)	1983-04-16	A PROCEDURE FOR THE PREPARATION OF ACID DERIVATIVES-S-AMINOACIL-3-MERCAPTOPROPANOILOS.

Legal Events

Date	Code	Title	Description
2002-04-16	FD1A	Patent lapsed	Effective date: 20020304