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ES2552651T3 - Composición inyectable de polidesoxirribonucleótido para el tratamiento de enfermedades osteoarticulares - Google Patents

Composición inyectable de polidesoxirribonucleótido para el tratamiento de enfermedades osteoarticulares Download PDF

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Publication number
ES2552651T3
ES2552651T3 ES09764046.0T ES09764046T ES2552651T3 ES 2552651 T3 ES2552651 T3 ES 2552651T3 ES 09764046 T ES09764046 T ES 09764046T ES 2552651 T3 ES2552651 T3 ES 2552651T3
Authority
ES
Spain
Prior art keywords
treatment
composition
polydeoxyribonucleotide
injectable
osteoarticular diseases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES09764046.0T
Other languages
English (en)
Inventor
Laura Cattarini Mastelli
Giulia Cattarini Mastelli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MASTELLI Srl
Original Assignee
MASTELLI Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40903256&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2552651(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by MASTELLI Srl filed Critical MASTELLI Srl
Application granted granted Critical
Publication of ES2552651T3 publication Critical patent/ES2552651T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/60—Fish, e.g. seahorses; Fish eggs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Detergent Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Composición a base de polidesoxirribonucleótidos, extraídos de fuentes naturales, para su uso mediante administración intraarticular en el tratamiento terapéutico y/o como coadyuvante terapéutico en el tratamiento de un estado degenerativo o postraumático de las articulaciones, en la que dichos polidesoxirribonucleótidos tienen pesos moleculares de entre 70 kDalton y 240 kDalton.

Description

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Claims (1)

  1. imagen1
ES09764046.0T 2008-10-30 2009-10-28 Composición inyectable de polidesoxirribonucleótido para el tratamiento de enfermedades osteoarticulares Active ES2552651T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITTO20080804 2008-10-30
ITTO2008A000804A IT1391866B1 (it) 2008-10-30 2008-10-30 Composizione iniettabile di polinucleotidi per il trattamento di patologie osteoarticolari.
PCT/IB2009/054776 WO2010049898A1 (en) 2008-10-30 2009-10-28 Injectable polydeoxyribonucleotide composition for the treatment of osteoarticular diseases

Publications (1)

Publication Number Publication Date
ES2552651T3 true ES2552651T3 (es) 2015-12-01

Family

ID=40903256

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09764046.0T Active ES2552651T3 (es) 2008-10-30 2009-10-28 Composición inyectable de polidesoxirribonucleótido para el tratamiento de enfermedades osteoarticulares

Country Status (11)

Country Link
US (1) US9220734B2 (es)
EP (1) EP2358373B1 (es)
CN (1) CN102238953B (es)
BR (1) BRPI0914410A2 (es)
DK (1) DK2358373T3 (es)
ES (1) ES2552651T3 (es)
IT (1) IT1391866B1 (es)
PL (1) PL2358373T3 (es)
PT (1) PT2358373E (es)
RU (1) RU2508115C2 (es)
WO (1) WO2010049898A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1401218B1 (it) * 2010-07-14 2013-07-12 Mastelli S R L Composizione ad attivita' bio-rigenerativa, riparativa ed eutrofizzante.
IT1406068B1 (it) * 2010-07-22 2014-02-06 Medestea Int Spa Polidesossiribonucleotidi (pdrn) per l'impiego nel trattamento di condizioni di acidosi e composizioni a base di polidesossiribonucleotidi per il suddetto impiego
KR101739409B1 (ko) 2011-10-21 2017-05-25 주식회사 파마리서치프로덕트 어류 정소로부터 분리된 디엔에이 단편 혼합물을 포함하는 연골 재생용 조성물
ITUB20153110A1 (it) * 2015-08-13 2017-02-13 Alfakjn S R L Composizione liquida iniettabile per uso nella terapia infiltrativa intra-articolare
ITUB20159447A1 (it) * 2015-12-28 2017-06-28 Mastelli S R L Composizione per il trattamento e prevenzione dell?osteoporosi.
CN107287186A (zh) * 2016-04-05 2017-10-24 达特珂贝怡股份有限公司 从鱼类的精液分离多脱氧核糖核苷酸的方法、由所述方法获得的多脱氧核糖核苷酸及其用途
KR102410132B1 (ko) * 2018-02-26 2022-06-17 주식회사 뉴온 조직 수복용 히알루론산 피부 충진제 조성물
KR102056144B1 (ko) * 2018-03-08 2019-12-16 주식회사 파마리서치프로덕트 Dna 단편 혼합물이 고농도로 함유된 유동성을 갖는 액제 조성물 및 이의 제조방법
KR102285724B1 (ko) * 2018-04-05 2021-08-03 김석순 Dna 단편 혼합물 및 히알루론산을 포함하는 연골 재생용 조성물
KR20190140654A (ko) 2018-06-12 2019-12-20 주식회사 비알팜 Dna 단편 혼합물 및 매트릭스 메탈로프로테아제 생성 억제제를 포함하는 관절염 예방 및 치료용 조성물
KR102242840B1 (ko) * 2019-04-04 2021-04-23 주식회사 비알팜 탈모 방지 또는 발모 촉진용 조성물
CN111214694B (zh) * 2020-03-31 2022-04-22 山东大鱼生物技术有限公司 一种具有止血和加速伤口愈合功能的敷料及其制备方法
KR102234367B1 (ko) * 2020-09-07 2021-03-31 바이오메디팜 어업회사법인 주식회사 연어의 정소로부터 고순도 피디알엔의 추출 방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3899481A (en) * 1970-11-03 1975-08-12 Crinos Industria Farmaco Process for the controlled partial degradation of deoxyribonucleic acid extracted from animal organs
IT1187833B (it) 1985-12-12 1987-12-23 Farmigea Spa Procedimento per l ottenimento di polidesossiribonucleotidi non informazionali sostanzialmente puri e dotati di attivita biologiche e prodotto relativo
FR2676926B1 (fr) * 1991-05-30 1993-10-01 Pierre Flecchia Compositions pharmaceutiques a base de polydesoxyribonucleotides et leur procede de preparation.
US5977083A (en) * 1991-08-21 1999-11-02 Burcoglu; Arsinur Method for using polynucleotides, oligonucleotides and derivatives thereof to treat various disease states
EP0786522A2 (en) * 1992-07-17 1997-07-30 Ribozyme Pharmaceuticals, Inc. Enzymatic RNA molecules for treatment of stenotic conditions
AU7319994A (en) * 1993-06-30 1995-01-24 Board Of Regents, The University Of Texas System Nucleotide preparation and uses thereof in wound healing
US6737271B1 (en) * 2000-03-24 2004-05-18 Biocell Laboratories Compound, composition and method for the treatment of inflammatory and inflammatory-related disorders
WO2003035048A2 (en) * 2001-10-26 2003-05-01 Novartis Ag Methods for the treatment of osteoarthritis and compositions thereof

Also Published As

Publication number Publication date
PT2358373E (pt) 2015-11-13
RU2011121612A (ru) 2012-12-10
PL2358373T3 (pl) 2016-02-29
IT1391866B1 (it) 2012-01-27
EP2358373B1 (en) 2015-09-09
US9220734B2 (en) 2015-12-29
ITTO20080804A1 (it) 2010-04-30
WO2010049898A1 (en) 2010-05-06
CN102238953B (zh) 2015-11-25
RU2508115C2 (ru) 2014-02-27
CN102238953A (zh) 2011-11-09
EP2358373A1 (en) 2011-08-24
DK2358373T3 (en) 2015-11-02
US20110196024A1 (en) 2011-08-11
BRPI0914410A2 (pt) 2016-08-16

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