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ES2123063T3 - Marcadores convertidores al alza para ensayos biologicos y otros mediante tecnicas de excitacion laser. - Google Patents

Marcadores convertidores al alza para ensayos biologicos y otros mediante tecnicas de excitacion laser.

Info

Publication number
ES2123063T3
ES2123063T3 ES93921595T ES93921595T ES2123063T3 ES 2123063 T3 ES2123063 T3 ES 2123063T3 ES 93921595 T ES93921595 T ES 93921595T ES 93921595 T ES93921595 T ES 93921595T ES 2123063 T3 ES2123063 T3 ES 2123063T3
Authority
ES
Spain
Prior art keywords
upgraded
markers
converter
laser excitation
biological tests
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93921595T
Other languages
English (en)
Inventor
David A Zarling
Michel J Rossi
Norman A Peppers
James Kane
Gregory W Faris
Mark J Dyer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SRI International Inc
Original Assignee
SRI International Inc
Stanford Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SRI International Inc, Stanford Research Institute filed Critical SRI International Inc
Application granted granted Critical
Publication of ES2123063T3 publication Critical patent/ES2123063T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
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    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
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    • G01N21/64—Fluorescence; Phosphorescence
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    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
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    • G01N21/645—Specially adapted constructive features of fluorimeters
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/588—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with semiconductor nanocrystal label, e.g. quantum dots
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    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00306—Reactor vessels in a multiple arrangement
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    • B01J2219/00315—Microtiter plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01J2219/00702—Processes involving means for analysing and characterising the products
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    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
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    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G01N2021/6419—Excitation at two or more wavelengths
    • G—PHYSICS
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    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
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    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
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  • Health & Medical Sciences (AREA)
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Abstract

LA INVENCION PROPORCIONA METODOS, COMPOSICIONES, Y APARATO PARA REALIZAR DETECCION SENSIBLE DE ANALITO, TAL COMO MACROMOLECULAS BIOLOGICAS Y OTROS ANALITOS, ETIQUETANDO UNA MOLECULA DE SONDA CON UNA ETIQUETA CONVERTIDORA DE FRECUENCIA. LA ETIQUETA CONVERTIDORA DE FRECUENCIA ABSORBE RADIACION DE UNA FUENTE DE ILUMINACION Y EMITE RADIACION EN UNA O MAS ALTAS FRECUENCIAS, PROPORCIONANDO UNA RELACION DE SEÑAL/RUIDO MEJORADA Y LA ELIMINACION ESENCIAL DE AUTOFLUORESCENCIA SUBORDINADA DE LA MUESTRA. LOS METODOS, COMPOSICIONES, Y APARATO SON ADECUADOS PARA LA DETECCION SENSIBLE DE ANALITOS MULTIPLES Y PARA VARIAS TECNICAS CLINICAS DE MUESTREO MEDIOAMBIENTAL.
ES93921595T 1992-09-14 1993-09-14 Marcadores convertidores al alza para ensayos biologicos y otros mediante tecnicas de excitacion laser. Expired - Lifetime ES2123063T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US94606892A 1992-09-14 1992-09-14

Publications (1)

Publication Number Publication Date
ES2123063T3 true ES2123063T3 (es) 1999-01-01

Family

ID=25483910

Family Applications (2)

Application Number Title Priority Date Filing Date
ES93921595T Expired - Lifetime ES2123063T3 (es) 1992-09-14 1993-09-14 Marcadores convertidores al alza para ensayos biologicos y otros mediante tecnicas de excitacion laser.
ES96200682T Expired - Lifetime ES2216034T3 (es) 1992-09-14 1993-09-14 Indicadores de conversion creciente destinados a ensayos biologicos y otros utilizando tecnicas de excitacion por laser.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES96200682T Expired - Lifetime ES2216034T3 (es) 1992-09-14 1993-09-14 Indicadores de conversion creciente destinados a ensayos biologicos y otros utilizando tecnicas de excitacion por laser.

Country Status (8)

Country Link
EP (3) EP0660936B1 (es)
JP (3) JP3420765B2 (es)
AT (3) ATE266195T1 (es)
CA (1) CA2144527C (es)
DE (3) DE69333502T2 (es)
DK (2) DK0723146T3 (es)
ES (2) ES2123063T3 (es)
WO (1) WO1994007142A1 (es)

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ES2288760T3 (es) 1996-04-25 2008-01-16 Bioarray Solutions Ltd. Ensamblaje electrocinetico controlado por luz de particulas proximas a superficies.
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DE69732510T2 (de) * 1996-10-31 2005-08-25 Fuji Photo Film Co., Ltd., Minami-Ashigara Bilderzeugende Vorrichtung
EP0968425B1 (en) * 1996-12-03 2003-06-25 SOINI, Erkki Biospecific, two photon excitation, fluorescence detection and device
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ATE170004T1 (de) 1998-09-15
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DE69320484T2 (de) 1998-12-24
ATE266195T1 (de) 2004-05-15
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EP0660936B1 (en) 1998-08-19
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ATE463744T1 (de) 2010-04-15
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