[go: up one dir, main page]

ES2117964T3 - Nuevas mezclas de gases propelentes y su uso en preparaciones medicas. - Google Patents

Nuevas mezclas de gases propelentes y su uso en preparaciones medicas.

Info

Publication number
ES2117964T3
ES2117964T3 ES91903275T ES91903275T ES2117964T3 ES 2117964 T3 ES2117964 T3 ES 2117964T3 ES 91903275 T ES91903275 T ES 91903275T ES 91903275 T ES91903275 T ES 91903275T ES 2117964 T3 ES2117964 T3 ES 2117964T3
Authority
ES
Spain
Prior art keywords
medical preparations
new mixtures
propellent gases
new
propellent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91903275T
Other languages
English (en)
Inventor
Hans-Hermann Weil
Ottfried Daab
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim GmbH
Original Assignee
Boehringer Ingelheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6399400&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2117964(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim GmbH filed Critical Boehringer Ingelheim GmbH
Application granted granted Critical
Publication of ES2117964T3 publication Critical patent/ES2117964T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/124—Aerosols; Foams characterised by the propellant
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K3/00—Materials not provided for elsewhere
    • C09K3/30—Materials not provided for elsewhere for aerosols

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Materials Engineering (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

NUEVAS MEZCLAS DE GASES PROPULSORES VENTAJOSAS QUE CONTIENEN DOS O MAS COMPONENTES, DE LOS QUE AL MENOS UNO ES UN ALCANO BAJO PARCIALMENTE FLUORIFICADO Y QUE PUEDEN APLICARSE EN PREPARADOS MEDICOS.
ES91903275T 1990-02-03 1991-01-31 Nuevas mezclas de gases propelentes y su uso en preparaciones medicas. Expired - Lifetime ES2117964T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4003272A DE4003272A1 (de) 1990-02-03 1990-02-03 Neue treibgasmischungen und ihre verwendung in arzneimittelzubereitungen

Publications (1)

Publication Number Publication Date
ES2117964T3 true ES2117964T3 (es) 1998-09-01

Family

ID=6399400

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91903275T Expired - Lifetime ES2117964T3 (es) 1990-02-03 1991-01-31 Nuevas mezclas de gases propelentes y su uso en preparaciones medicas.

Country Status (24)

Country Link
US (1) US6413497B1 (es)
EP (1) EP0514415B1 (es)
JP (1) JP3497161B2 (es)
AT (1) ATE165863T1 (es)
AU (1) AU650001B2 (es)
CA (1) CA2075058C (es)
CZ (1) CZ286691B6 (es)
DE (2) DE4003272A1 (es)
DK (1) DK0514415T3 (es)
ES (1) ES2117964T3 (es)
FI (1) FI102905B1 (es)
HK (1) HK1010786A1 (es)
HR (1) HRP940735B1 (es)
HU (2) HU9202509D0 (es)
IE (2) IE910351A1 (es)
IL (1) IL97028A (es)
NO (1) NO302419B1 (es)
NZ (1) NZ236973A (es)
PT (1) PT96634B (es)
SI (1) SI9110156B (es)
SK (1) SK280426B6 (es)
WO (1) WO1991011495A1 (es)
YU (1) YU49203B (es)
ZA (1) ZA91754B (es)

Families Citing this family (104)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225183A (en) * 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
US5766573A (en) * 1988-12-06 1998-06-16 Riker Laboratories, Inc. Medicinal aerosol formulations
DE4003270A1 (de) * 1990-02-03 1991-08-08 Boehringer Ingelheim Kg Neue treibgase und ihre verwendung in arzneimittelzubereitungen
EP0536204B1 (en) * 1990-06-27 1994-04-06 Minnesota Mining And Manufacturing Company The use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations
AU658854B2 (en) * 1990-10-18 1995-05-04 Minnesota Mining And Manufacturing Company Aerosol formulation comprising beclomethasone 17,21 dipropionate
MX9203481A (es) 1990-10-18 1992-07-01 Minnesota Mining & Mfg Formulaciones.
HU205249B (en) * 1990-11-09 1992-04-28 Egyt Gyogyszervegyeszeti Gyar Process for producing suspensive aerosole composition
GB9024366D0 (en) * 1990-11-09 1991-01-02 Glaxo Group Ltd Medicaments
US5182040A (en) * 1991-03-28 1993-01-26 E. I. Du Pont De Nemours And Company Azeotropic and azeotrope-like compositions of 1,1,2,2-tetrafluoroethane
US5725791A (en) * 1991-03-28 1998-03-10 E. I. Du Pont De Nemours And Company Azeotropic and azeotrope-like compositions of 1,1,2,2-tetrafluoroethane
SK140493A3 (en) * 1991-06-10 1994-10-05 Schering Corp Non-chlorofluorocarbon aerosol formulations
ATE226067T1 (de) 1991-06-10 2002-11-15 Schering Corp Fluorchlorkohlenwasserstofffreie aerosolformulierungen
DE4123663A1 (de) * 1991-07-17 1993-01-21 Schwabe Willmar Gmbh & Co Aerosol-zubereitung und verwendung eines treibmittels dafuer
IL104068A (en) * 1991-12-12 1998-10-30 Glaxo Group Ltd Surfactant-free pharmaceutical aerosol formulation comprising 1,1,1,2-tetrafluoroethane or 1,1,1,2,3,3,3-heptafluoro-n- propane as propellant
ES2079210T3 (es) * 1991-12-12 1996-01-01 Glaxo Group Ltd Formulacion farmaceutica de aerosol.
ATE171865T1 (de) * 1991-12-12 1998-10-15 Glaxo Group Ltd Arzneimittel
US5658549A (en) * 1991-12-12 1997-08-19 Glaxo Group Limited Aerosol formulations containing propellant 134a and fluticasone propionate
US5674471A (en) * 1991-12-12 1997-10-07 Glaxo Group Limited Aerosol formulations containing P134a and salbutamol
US5744123A (en) * 1991-12-12 1998-04-28 Glaxo Group Limited Aerosol formulations containing P134a and particulate medicaments
US5683676A (en) * 1991-12-12 1997-11-04 Glaxo Group Limited Canister containing aerosol formulations containing P134a and particulate medicaments
US5736124A (en) * 1991-12-12 1998-04-07 Glaxo Group Limited Aerosol formulations containing P134a and particulate medicament
US5916540A (en) 1994-10-24 1999-06-29 Glaxo Group Limited Aerosol formulations containing P134A and/or P227 and particulate medicament
US7105152B1 (en) 1991-12-18 2006-09-12 3M Innovative Properties Company Suspension aerosol formulations
US7101534B1 (en) 1991-12-18 2006-09-05 3M Innovative Properties Company Suspension aerosol formulations
US20030103907A1 (en) * 1991-12-18 2003-06-05 Schultz Robert K. Suspension aerosol formulations
NZ246421A (en) * 1991-12-18 1996-05-28 Minnesota Mining & Mfg Aerosol formulation containing a drug and a propellant and which is substantially free of surfactant
DE4203306A1 (de) * 1992-02-06 1993-08-12 Ig Spruehtechnik Gmbh Asthma oder pulmonal-aerosolzubereitungen mit lecithin
DE4230876A1 (de) 1992-03-17 1993-09-23 Asta Medica Ag Druckgaspackungen unter verwendung von polyoxyethylen-glyceryl-oleaten
EP0639148A1 (en) * 1992-05-04 1995-02-22 Minnesota Mining And Manufacturing Company Device for delivering an aerosol
DE4218291A1 (de) * 1992-06-03 1993-12-09 Mattern Et Partner Pharmazeuti Dosierspray für pernasale Applikation
US5833950A (en) * 1992-07-31 1998-11-10 Glaxo Group Limited Aerosol formulations containing beclomethasone dipropionate-1, 1, 1, 2-tetrafluoroethane solvate
WO1994004629A1 (en) * 1992-08-21 1994-03-03 E.I. Du Pont De Nemours And Company Substantially constant boiling mixtures of 1,1,1,2-tetrafluoroethane, dimethyl ether and isobutane
WO1994013263A1 (en) * 1992-12-09 1994-06-23 Jager Paul D Stabilized medicinal aerosol solution formulations
US5458798A (en) * 1993-02-05 1995-10-17 E. I. Du Pont De Nemours And Company Azeotropic and azeotrope-like compositions of a hydrofluorocarbon and a hydrocarbon
US5474758A (en) * 1993-07-28 1995-12-12 Minnesota Mining And Manufacturing Company Seals for use in an aerosol delivery device
CA2178473C (en) * 1993-12-20 2004-08-24 Tsi-Zong Tzou Flunisolide aerosol formulations
CH686806A5 (de) * 1994-01-12 1996-06-28 Cerberus Ag Gasgemisch zur Funktionspruefung von Rauchmeldern.
US6001273A (en) 1994-03-11 1999-12-14 Minor; Barbara Haviland Binary azeotropes of difluoromethane and hydrocarbons
US5417871A (en) * 1994-03-11 1995-05-23 E. I. Du Pont De Nemours And Company Hydrofluorocarbon compositions
GB9419536D0 (en) * 1994-09-28 1994-11-16 Glaxo Inc Medicaments
DE69530325T2 (de) 1994-12-22 2004-02-19 Astrazeneca Ab Aerosol-arzneiformulierungen
US6524557B1 (en) 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
US6013245A (en) * 1995-01-26 2000-01-11 Glaxo Group Limited Aerosol formulation containing beclomethasone dipropionate and 1,1,1,2,3,3,3-heptafluoro-n-propane as propellant
GB9507768D0 (en) 1995-04-13 1995-05-31 Glaxo Group Ltd Method of apparatus
US6054488A (en) * 1996-06-11 2000-04-25 3M Innovative Properties Company Medicinal aerosol formulations of formoterol
GB9616237D0 (en) 1996-08-01 1996-09-11 Norton Healthcare Ltd Aerosol formulations
GB9620187D0 (en) † 1996-09-27 1996-11-13 Minnesota Mining & Mfg Medicinal aerosol formulations
US6039932A (en) * 1996-09-27 2000-03-21 3M Innovative Properties Company Medicinal inhalation aerosol formulations containing budesonide
EP1014943B1 (de) 1997-02-05 2002-06-19 Jago Research Ag Medizinische aerosolformulierungen
US6120752A (en) * 1997-05-21 2000-09-19 3M Innovative Properties Company Medicinal aerosol products containing formulations of ciclesonide and related steroids
US6086376A (en) * 1998-01-30 2000-07-11 Rtp Pharma Inc. Dry aerosol suspension of phospholipid-stabilized drug microparticles in a hydrofluoroalkane propellant
GB9805938D0 (en) 1998-03-19 1998-05-13 Glaxo Group Ltd Valve for aerosol container
US6264923B1 (en) 1998-05-13 2001-07-24 3M Innovative Properties Company Medicinal aerosol formulation of ciclesonide and related compounds
US6423298B2 (en) * 1998-06-18 2002-07-23 Boehringer Ingelheim Pharmaceuticals, Inc. Pharmaceutical formulations for aerosols with two or more active substances
ATE283033T1 (de) 1998-07-24 2004-12-15 Jago Res Ag Medizinische aerosolformulierungen
EP1102579B1 (de) * 1998-08-04 2003-03-19 Jago Research Ag Medizinische aerosolformulierungen
US6458338B1 (en) * 1998-09-22 2002-10-01 Aeropharm Technology Incorporated Amino acid stabilized medicinal aerosol formulations
ATE294608T1 (de) 1999-06-05 2005-05-15 Innovata Biomed Ltd Verabreichungsystem für medikamente
GB9920839D0 (en) 1999-09-04 1999-11-10 Innovata Biomed Ltd Inhaler
US7217409B2 (en) 2000-09-22 2007-05-15 Smithkline Beecham Corporation Alkanoic acid derivatives
US20020193392A1 (en) * 2000-11-13 2002-12-19 Christel Schmelzer Pharmaceutical compositions based on tiotropium salts of salts of salmeterol
HU229899B1 (en) 2000-12-22 2014-12-29 Glaxo Group Ltd Brentford Metered dose inhaler for salmeterol xinafoate
US20110301569A1 (en) 2001-01-20 2011-12-08 Gordon Wayne Dyer Methods and apparatus for the CVCS
US20030018019A1 (en) * 2001-06-23 2003-01-23 Boehringer Ingelheim Pharma Kg Pharmaceutical compositions based on anticholinergics, corticosteroids and betamimetics
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
US6919325B2 (en) 2001-09-14 2005-07-19 Boehringer Ingelheim Pharma Kg Pharmaceutical compositions containing tiotropium salts and low-solubility salmeterol salts
GB0128148D0 (en) 2001-11-23 2002-01-16 Innovata Biomed Ltd Assembly
AU2003205860A1 (en) 2002-02-13 2003-09-04 Glaxo Group Limited Carboxylic acid compounds for use as surfactants
GB0205327D0 (en) 2002-03-06 2002-04-17 Glaxo Group Ltd compounds
US7754242B2 (en) * 2002-03-20 2010-07-13 Alkermes, Inc. Inhalable sustained therapeutic formulations
US7582284B2 (en) 2002-04-17 2009-09-01 Nektar Therapeutics Particulate materials
US7279451B2 (en) * 2002-10-25 2007-10-09 Honeywell International Inc. Compositions containing fluorine substituted olefins
US20040152720A1 (en) * 2002-12-20 2004-08-05 Boehringer Ingelheim Pharma Gmbh & Co. Kg Powdered medicaments containing a tiotropium salt and salmeterol xinafoate
JP2006527237A (ja) 2003-06-13 2006-11-30 アルタナ　ファルマ　アクチエンゲゼルシャフト ホルモテロールと及びシクレソニドの組合せ物
AU2004264941B2 (en) 2003-08-11 2008-11-27 Glaxo Group Limited Pharmaceutical metered dose inhaler and methods relating thereto
CN1874756B (zh) 2003-08-29 2012-02-29 葛兰素集团有限公司 药用计量剂量吸入器和其相关方法
PL1670482T5 (pl) 2003-09-16 2022-10-03 Covis Pharma Gmbh Zastosowanie cyklezonidu w leczeniu chorób układu oddechowego
AR041873A1 (es) * 2003-10-30 2005-06-01 Pablo Cassara Srl Lab Una formulacion farmaceutica en aerosol adecuada para la inhalacion oral o nasal que contienen glucocorticoides en solucion estable al almacenamiento; un metodo para estabilzar formulaciones y uso de un agente estabilizante
WO2005102429A1 (en) 2004-04-21 2005-11-03 Innovata Biomed Limited Inhaler
ES2691033T3 (es) 2007-02-11 2018-11-23 Map Pharmaceuticals Inc. Método de administración terapéutica de DHE para activar el alivio rápido de la migraña a la vez que se reduce al mínimo el perfil de los efectos secundarios
CA2747790A1 (en) 2009-01-05 2010-07-08 Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V. Means and method for the treatment of antibody deficiency diseases based on il-21 and il-21 variants
US20110124589A1 (en) 2009-11-24 2011-05-26 Gilead Sciences, Inc. Inhaled fosfomycin/tobramycin for the treatment of chronic obstructive pulmonary disease
WO2011081937A1 (en) 2009-12-15 2011-07-07 Gilead Sciences, Inc. Corticosteroid-beta-agonist-muscarinic antagonist compounds for use in therapy
AR079451A1 (es) 2009-12-18 2012-01-25 Nycomed Gmbh Compuestos 3,4,4a,10b-tetrahidro-1h-tiopirano[4,3-c]isoquinolina
AU2011253203A1 (en) 2010-05-10 2012-11-22 Gilead Sciences, Inc. Bifunctional quinoline derivatives
WO2011143106A1 (en) 2010-05-10 2011-11-17 Gilead Sciences, Inc. Bi - functional pyrazolopyridine compounds
US20130274171A1 (en) 2010-06-04 2013-10-17 Trifoilium Aps Trefoil factors (tff) for the treatment of chronic pulmonary diseases
EP2613773A2 (en) 2010-09-09 2013-07-17 Trifoilium ApS Airway administration of angiogenesis inhibitors
GB201108039D0 (en) 2011-05-13 2011-06-29 Mexichem Amanco Holding Sa Compositions
JP2014519519A (ja) 2011-06-15 2014-08-14 タケダ ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規３，４，４ａ，１０ｂ−テトラヒドロ−１Ｈ−チオピラノ［４，３−ｃ］イソキノリン化合物
AR086915A1 (es) 2011-06-17 2014-01-29 Nycomed Gmbh Derivados de ftalazinona-pirrolopirimidinacarboxamida y composiciones farmaceuticas que los contiene
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
GB201117621D0 (en) 2011-10-12 2011-11-23 Mexichem Amanco Holding Sa Compositions
GB201117619D0 (en) 2011-10-12 2011-11-23 Mexichem Amanco Holding Sa Compositions
DK2855435T3 (en) 2012-05-29 2018-07-16 Parion Sciences Inc DENDRIMER-LIKE AMINOAMIDES WITH SODIUM CHANNEL BLOCKING ACTIVITY FOR THE TREATMENT OF DRY EYES AND OTHER MILK DISEASES
US9029382B2 (en) 2012-12-17 2015-05-12 Parion Sciences, Inc. 3,5-diamino-6-chloro-N-(N-(4-phenylbutyl)carbamimidoyl) pyrazine-2-carboxamide compounds
ES2674665T3 (es) 2012-12-17 2018-07-03 Parion Sciences, Inc. Compuestos de 3,5-diamino-6-cloro-N-(N-(4-fenilbutilo)carbamimidoilo)-pirazina-2-carboxamida
BR112015014349A2 (pt) 2012-12-17 2017-07-11 Parion Sciences Inc derivados de cloro-pirazina carboxamida úteis para o tratamento de doenças favorecidas por hidratação mucosa insuficiente
GB201306984D0 (en) * 2013-04-17 2013-05-29 Mexichem Amanco Holding Sa Composition
ES2796177T5 (es) 2015-12-04 2024-10-29 Mexichem Fluor Sa De Cv Composición farmacéutica
ES2877575T3 (es) 2016-09-19 2021-11-17 Mexichem Fluor Sa De Cv Composición farmacéutica que comprende salmeterol
PE20191043A1 (es) 2016-09-19 2019-08-06 Mexichem Fluor Sa De Cv Composicion farmaceutica
CN109715160A (zh) 2016-09-19 2019-05-03 墨西哥氟石股份公司 药物组合物
WO2018069210A1 (en) 2016-10-10 2018-04-19 Takeda Gmbh Tetrahydrofuro[3,4-c]isoquinolines as inhibitors of pde4

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB902590A (en) 1960-03-22 1962-08-01 Allied Chem Production of heptafluoropropane
DE1542076A1 (de) * 1966-04-21 1970-03-26 Colgate Palmolive Co Aerosol-Treibmittel
MX3864E (es) 1975-05-27 1981-08-26 Syntex Corp Un proceso para prepara el compuesto cristalino 6-fluiro-11b 21-dihiroxi-16 17-isopropilidendioxipregna-1 4-dien-3 20-diona
US4405598A (en) 1976-01-30 1983-09-20 Fisons, Limited Composition for treating asthma
NL7708731A (nl) * 1976-08-13 1978-02-15 Montedison Spa Werkwijze voor de bereiding van nieuwe drijf- middelsamenstellingen voor aerosolen.
JPS5325284A (en) * 1976-08-19 1978-03-08 Daikin Ind Ltd Aerosol composition
US4352789A (en) 1980-03-17 1982-10-05 Minnesota Mining And Manufacturing Company Aerosol compositions containing finely divided solid materials
JPS5734174A (en) * 1980-08-11 1982-02-24 Toyo Aerosol Kogyo Kk Powdered aerosol composition
GB8613811D0 (en) * 1986-06-06 1986-07-09 Phares Pharm Res Nv Composition & method
GB8501015D0 (en) * 1985-01-16 1985-02-20 Riker Laboratories Inc Drug
US4778674A (en) * 1986-05-28 1988-10-18 Richardson-Vicks Inc. Dry aerosol foam
EP0318492A1 (en) 1986-08-11 1989-06-07 Innovata Biomed Limited Pharmaceutical formulations comprising microcapsules
DE3815480A1 (de) 1988-05-06 1989-11-16 Boehringer Ingelheim Kg Synergistische kombinationen und ihre verwendung als therapeutika
US5225183A (en) * 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
DE3905726A1 (de) * 1989-02-24 1990-08-30 Hoechst Ag Druckgaspackung und treibmittel fuer aerosole
US5118494A (en) * 1990-03-23 1992-06-02 Minnesota Mining And Manufacturing Company Use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations
MX9203481A (es) * 1990-10-18 1992-07-01 Minnesota Mining & Mfg Formulaciones.
US5190029A (en) * 1991-02-14 1993-03-02 Virginia Commonwealth University Formulation for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content
US6013245A (en) * 1995-01-26 2000-01-11 Glaxo Group Limited Aerosol formulation containing beclomethasone dipropionate and 1,1,1,2,3,3,3-heptafluoro-n-propane as propellant
US6039932A (en) * 1996-09-27 2000-03-21 3M Innovative Properties Company Medicinal inhalation aerosol formulations containing budesonide
US6004537A (en) * 1998-12-18 1999-12-21 Baker Norton Pharmaceuticals, Inc. Pharmaceutical solution aerosol formulations containing fluoroalkanes, budesonide and formoterol

Also Published As

Publication number Publication date
FI923490L (fi) 1992-08-03
FI102905B (fi) 1999-03-15
IL97028A0 (en) 1992-03-29
CS26491A3 (en) 1991-09-15
PT96634A (pt) 1991-10-31
SI9110156A (sl) 1998-04-30
IE910351A1 (en) 1991-08-14
US6413497B1 (en) 2002-07-02
AU7211391A (en) 1991-08-21
ZA91754B (en) 1992-10-28
JP3497161B2 (ja) 2004-02-16
IE910350A1 (en) 1991-08-14
YU15691A (sh) 1994-01-20
HU218784B (hu) 2000-12-28
PT96634B (pt) 1998-07-31
SI9110156B (sl) 1999-04-30
CZ286691B6 (cs) 2000-06-14
AU650001B2 (en) 1994-06-09
DE4003272A1 (de) 1991-08-08
WO1991011495A1 (de) 1991-08-08
NO302419B1 (no) 1998-03-02
EP0514415B1 (de) 1998-05-06
EP0514415A1 (de) 1992-11-25
NO923039L (no) 1992-07-31
DE59108979D1 (de) 1998-06-10
NO923039D0 (no) 1992-07-31
IL97028A (en) 1994-08-26
HRP940735B1 (en) 1999-10-31
CA2075058C (en) 2001-03-27
HUT62456A (en) 1993-05-28
FI923490A0 (fi) 1992-08-03
HRP940735A2 (en) 1997-06-30
CA2075058A1 (en) 1991-08-04
DK0514415T3 (da) 1998-10-07
NZ236973A (en) 1993-08-26
FI102905B1 (fi) 1999-03-15
YU49203B (sh) 2004-09-03
SK280426B6 (sk) 2000-02-14
JPH05504160A (ja) 1993-07-01
HU9202509D0 (en) 1992-10-28
HK1010786A1 (en) 1999-06-25
ATE165863T1 (de) 1998-05-15

Similar Documents

Publication Publication Date Title
ES2117964T3 (es) Nuevas mezclas de gases propelentes y su uso en preparaciones medicas.
ES490029A0 (es) Un aparato fraccionador de gases y procedimiento para redu- cir la concentracion de uno o mas gases, que lo usa
ES2075050T3 (es) Peptidos que tienen actividad cooperadora de celulas t.
FR2599505B1 (fr) Analyseur de gaz photoacoustique
FI924624A7 (fi) Laite vedyn ja hapen uudestaanyhdistämiseksi ja laitteen käyttö
MX9204522A (es) Derivados 4-benzoil-isoxazol, procedimiento para su preparacion y composicion herbicida que los contiene.
ES2100151T3 (es) Nuevos derivados de benzopirano, procedimientos para su preparacion y su uso y composiciones que contienen los compuestos.
DK168990A (da) Blande/aelteapparat og fremgangsmaade ved fremstilling af dej, navnlig til makaronivarer
MX148173A (es) Membrana mejorada de componentes multiples para separacion de gases,y procedimiento para su preparacion
DE3751212D1 (de) Eichung von kombinierten Sauerstoff- und Brennstoffanalysegeräten.
FI885062L (fi) Kalibreringsfoerfarande och kalibrerbar givarkonstruktion foer maetning av den relativa halten av gas eller aonga.
ATE293614T1 (de) Nicht-steroidale polyzyklische sulfamat-derivate, deren herstellung und deren verwendung als östron sulfatase inhibitoren
ES2160706T3 (es) Articulos de caucho con una permeabilidad a los gases.
NO873286D0 (no) Gassblande- og -tilfoerselsapparat.
NO901038L (no) Fremgangsmaate og arrangement for gjenvinning av de tyngrehydrokarboner i gassformete blandinger.
MX9302927A (es) Nuevos peptidos, la preparacion y utilizacion de los mimos.
DK511389D0 (da) Lav nox atmosfaerisk gas braender
ES2056838T3 (es) Agente para la regulacion del apetito o un agente hipnotico.
AR207270A1 (es) Preparaciones liquidas acuosas de colorantes procedentes de colorantes reactivos que son 1-(4"-sulfofenil)-3-metil-5-pirazol-5-ona-4-il-azo-(2'-metoxi-5'metil-(4"-sulfofenil)-3-metil-5-pira-4'-(beta-sulfatoetil))-benceno y 1-zol-5-ona-4-il-azo-(2',5'-dimetoxi-4'-(beta-sulfatoetil))-bencen
NO923477D0 (no) Fremgangsmaate ved fremstilling av en beskyttende gass, ogen gassblanding derfor
DE69019378D1 (de) Odorierung von sauerstoffgas mit einer übelriechenden substanz und dafür geeignete flüssige mischung.
NO891081D0 (no) Fremgangsmaate ved oksydasjon av en oksyderbar sats gassfase og reaktor for utfoerelse av fremgangsmaaten.
NO875135L (no) Fremgangsmaate for fremstilling av kerosen og/eller gassolje.
IT8025482A0 (it) Membrana modificata morfologicamente ed uso della stessa in procedimenti di elettrolisi.
DK31889A (da) Anvendelse af cyclophilin som antiinflammatorisk og immunmodulerende middel.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 514415

Country of ref document: ES