ES2115535A1 - Procedimiento para la preparacion de amidas de d-(-)-aminoacidos. - Google Patents
Procedimiento para la preparacion de amidas de d-(-)-aminoacidos.Info
- Publication number
- ES2115535A1 ES2115535A1 ES09601209A ES9601209A ES2115535A1 ES 2115535 A1 ES2115535 A1 ES 2115535A1 ES 09601209 A ES09601209 A ES 09601209A ES 9601209 A ES9601209 A ES 9601209A ES 2115535 A1 ES2115535 A1 ES 2115535A1
- Authority
- ES
- Spain
- Prior art keywords
- amino acid
- acid amides
- preparation
- amides
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 title abstract 3
- 238000002360 preparation method Methods 0.000 title abstract 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000003782 beta lactam antibiotic agent Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE AMIDAS DE D-(-)AMINOACIDOS. EL PROCEDIMIENTO DE OBTENCION DE LAS AMIDAS DE D-(-)-AMINOACIDOS, DE FORMULA (I), DONDE R ES HIDROGENO O UN RADICAL DERIVADO DE UN AMINOACIDO, OPCIONALMENTE SUSTITUIDO, COMPRENDE HACER REACCIONAR UNA SAL DE UN ESTER DE UN D-(-)-AMINOACIDO DE FORMULA (II), DONDE R" ES UN GRUPO ALQUILO LINEAL O RAMIFICADO DE 1 A 6 ATOMOS DE CARBONO, Y X ES EL ANION DE LA SAL, CON UNA DISOLUCION ACUOSA DE AMONIACO A UNA TEMPERATURA COMPRENDIDA ENTRE 0 Y 40C. LAS AMIDAS (I) SON IMPORTANTES INTERMEDIOS PARA LA SINTESIS DE ANTIBIOTICOS BE-LACTAMICOS SEMISINTETICOS POR VIA ENZIMATICA.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9601209A ES2115535B1 (es) | 1996-05-31 | 1996-05-31 | Procedimiento para la preparacion de amidas de d-(-)-aminoacidos. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9601209A ES2115535B1 (es) | 1996-05-31 | 1996-05-31 | Procedimiento para la preparacion de amidas de d-(-)-aminoacidos. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2115535A1 true ES2115535A1 (es) | 1998-06-16 |
| ES2115535B1 ES2115535B1 (es) | 1999-02-01 |
Family
ID=8294998
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES9601209A Expired - Lifetime ES2115535B1 (es) | 1996-05-31 | 1996-05-31 | Procedimiento para la preparacion de amidas de d-(-)-aminoacidos. |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES2115535B1 (es) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118878433A (zh) * | 2024-09-24 | 2024-11-01 | 浙江昂利康制药股份有限公司 | 一种d(-)对羟基苯甘氨酸甲酯盐酸盐的制备方法 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995018112A1 (en) * | 1993-12-24 | 1995-07-06 | Oxford Asymmetry Limited | Improvements in or relating to chiral auxiliaries |
-
1996
- 1996-05-31 ES ES9601209A patent/ES2115535B1/es not_active Expired - Lifetime
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995018112A1 (en) * | 1993-12-24 | 1995-07-06 | Oxford Asymmetry Limited | Improvements in or relating to chiral auxiliaries |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118878433A (zh) * | 2024-09-24 | 2024-11-01 | 浙江昂利康制药股份有限公司 | 一种d(-)对羟基苯甘氨酸甲酯盐酸盐的制备方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2115535B1 (es) | 1999-02-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC2A | Transfer of patent | ||
| EC2A | Search report published |
Date of ref document: 19980616 Kind code of ref document: A1 Effective date: 19980616 |
|
| FA2A | Application withdrawn |
Effective date: 19991026 |