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ES2191638T3 - Comprimidos escasamente dosificados y procedimiento para su preparacion. - Google Patents

Comprimidos escasamente dosificados y procedimiento para su preparacion.

Info

Publication number
ES2191638T3
ES2191638T3 ES00958607T ES00958607T ES2191638T3 ES 2191638 T3 ES2191638 T3 ES 2191638T3 ES 00958607 T ES00958607 T ES 00958607T ES 00958607 T ES00958607 T ES 00958607T ES 2191638 T3 ES2191638 T3 ES 2191638T3
Authority
ES
Spain
Prior art keywords
dosed
lowly
compressed
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES00958607T
Other languages
English (en)
Inventor
Guy Couarraze
Bernard Leclerc
Pierre Tchoreloff
Patrick Sanial
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ethypharm SAS
Original Assignee
Ethypharm SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethypharm SAS filed Critical Ethypharm SAS
Application granted granted Critical
Publication of ES2191638T3 publication Critical patent/ES2191638T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Comprimido de microgránulos escasamente dosificado en principio activo que contiene un diluyente directamente comprimible, caracterizado porque el diluyente directamente comprimible está constituido exclusivamente por microgránulos neutros, y porque el principio activo se coloca sobre los microgránulos neutros y no está recubierto con un agente destinado a modificar su liberación o a enmascarar su sabor.
ES00958607T 1999-07-26 2000-07-25 Comprimidos escasamente dosificados y procedimiento para su preparacion. Expired - Lifetime ES2191638T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9909653A FR2796840B1 (fr) 1999-07-26 1999-07-26 Comprimes faiblement doses et procede de preparation

Publications (1)

Publication Number Publication Date
ES2191638T3 true ES2191638T3 (es) 2003-09-16

Family

ID=9548499

Family Applications (1)

Application Number Title Priority Date Filing Date
ES00958607T Expired - Lifetime ES2191638T3 (es) 1999-07-26 2000-07-25 Comprimidos escasamente dosificados y procedimiento para su preparacion.

Country Status (29)

Country Link
US (2) US8337892B1 (es)
EP (1) EP1200071B1 (es)
JP (1) JP4812211B2 (es)
KR (1) KR100649949B1 (es)
CN (1) CN1172660C (es)
AT (1) ATE236621T1 (es)
AU (1) AU774801B2 (es)
BG (1) BG65535B1 (es)
BR (1) BR0012775A (es)
CA (1) CA2391240C (es)
CZ (1) CZ300238B6 (es)
DE (1) DE60002089T2 (es)
DK (1) DK1200071T3 (es)
DZ (1) DZ3208A1 (es)
ES (1) ES2191638T3 (es)
FR (1) FR2796840B1 (es)
HR (1) HRP20020165B1 (es)
HU (1) HU228638B1 (es)
IL (2) IL147682A0 (es)
MA (1) MA25424A1 (es)
MX (1) MXPA02000922A (es)
NO (1) NO331905B1 (es)
NZ (1) NZ516726A (es)
PL (1) PL201215B1 (es)
PT (1) PT1200071E (es)
SK (1) SK285514B6 (es)
TR (1) TR200200198T2 (es)
WO (1) WO2001006982A2 (es)
ZA (1) ZA200200380B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2852607B1 (fr) * 2003-03-20 2006-07-14 Procede de fabrication de microspheres de sucre de petite taille, les microspheres susceptibles d'etre obtenues par ce procede et leurs applications
FR2861990B1 (fr) * 2003-11-10 2006-02-10 Nouveaux Produits Pharma Comprimes faiblement doses a reseau de polymeres
EP1568369A1 (en) 2004-02-23 2005-08-31 Boehringer Ingelheim Vetmedica Gmbh Use of meloxicam for the treatment of respiratory diseases in pigs
ES2702608T3 (es) * 2004-06-10 2019-03-04 Glatt Air Techniques Inc Formulación de dosificación farmacéutica con matriz de liberación controlada
FR2883179B1 (fr) 2005-03-18 2009-04-17 Ethypharm Sa Comprime enrobe
US9795568B2 (en) 2010-05-05 2017-10-24 Boehringer Ingelheim Vetmedica Gmbh Low concentration meloxicam tablets
FR2960775A1 (fr) 2010-06-07 2011-12-09 Ethypharm Sa Microgranules resistants au detournement
CN102416003A (zh) * 2011-12-08 2012-04-18 南京优科生物医药有限公司 一种制备恩替卡韦片剂的方法
JP5897196B1 (ja) * 2015-10-05 2016-03-30 大同化成工業株式会社 糖又は糖アルコール、膨潤型結合剤、崩壊剤及び高吸収性賦形剤を含む複合化造粒物及びその製造方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2996431A (en) * 1953-12-16 1961-08-15 Barry Richard Henry Friable tablet and process for manufacturing same
US3568828A (en) * 1967-03-01 1971-03-09 Squibb & Sons Inc Modified sequential oral contraceptive
US4634587A (en) * 1982-07-09 1987-01-06 Key Pharmaceuticals, Inc. Sustained release quinidine dosage form
US4489026A (en) * 1982-09-07 1984-12-18 The Upjohn Company Process for preparing solid unit dosage forms of ultra-low dose drugs
US4684516A (en) * 1983-08-01 1987-08-04 Alra Laboratories, Inc. Sustained release tablets and method of making same
GB8414220D0 (en) * 1984-06-04 1984-07-11 Sterwin Ag Medicaments in unit dose form
WO1988002629A1 (en) * 1986-10-16 1988-04-21 American Health Products Corporation 2',3'-didesoxyadenosine composition
US5026560A (en) * 1987-01-29 1991-06-25 Takeda Chemical Industries, Ltd. Spherical granules having core and their production
US4925674A (en) * 1988-08-25 1990-05-15 Himedics, Inc. Amoxicillin microencapsulated granules
NZ230763A (en) * 1988-09-27 1991-10-25 Takeda Chemical Industries Ltd Production of granules having a core by spraying the cores with a dispersion of hydroxypropylcellulose, optionally incorporating an active ingredient
US4966770A (en) * 1989-07-26 1990-10-30 Himedics, Inc. Prednisone microencapsulated granules
US4983399A (en) * 1989-10-18 1991-01-08 Eastman Kodak Company Direct compression carrier composition
JP2820829B2 (ja) * 1991-03-07 1998-11-05 武田薬品工業株式会社 有核散剤およびその製造方法
IE67345B1 (en) * 1991-03-12 1996-03-20 Akzo Nv Low dose dry pharmaceutical preparations
AR004178A1 (es) * 1995-07-29 1998-11-04 Smithkline Beecham Plc Procedimiento para la formulacion de un farmaco, una composicion farmaceutica obtenible mediante este procedimiento y el uso de la misma.
SE9600046D0 (sv) * 1996-01-05 1996-01-05 Astra Ab New pharmaceutical formulation
GB9619074D0 (en) * 1996-09-12 1996-10-23 Smithkline Beecham Plc Composition
FR2816507B1 (fr) * 2000-11-16 2003-02-28 Ethypharm Lab Prod Ethiques Microgranules a base de principe actif, procede de fabrication et compositons pharmaceutiques integrant lesdits microgranules

Also Published As

Publication number Publication date
JP2003505402A (ja) 2003-02-12
PL353134A1 (en) 2003-10-20
NO20020243D0 (no) 2002-01-16
CN1172660C (zh) 2004-10-27
NO331905B1 (no) 2012-04-30
AU774801B2 (en) 2004-07-08
ATE236621T1 (de) 2003-04-15
BR0012775A (pt) 2002-04-02
HU228638B1 (hu) 2013-04-29
HRP20020165B1 (en) 2004-06-30
MXPA02000922A (es) 2002-07-30
NO20020243L (no) 2002-03-13
CZ300238B6 (cs) 2009-03-25
HUP0202228A3 (en) 2004-05-28
FR2796840B1 (fr) 2003-06-20
CA2391240C (fr) 2011-05-31
KR100649949B1 (ko) 2006-11-27
HUP0202228A2 (hu) 2002-11-28
SK285514B6 (sk) 2007-03-01
IL147682A0 (en) 2002-08-14
AU7007600A (en) 2001-02-13
US8337892B1 (en) 2012-12-25
CA2391240A1 (fr) 2001-02-01
DZ3208A1 (fr) 2001-02-01
EP1200071B1 (fr) 2003-04-09
SK932002A3 (en) 2002-08-06
PT1200071E (pt) 2003-08-29
MA25424A1 (fr) 2002-04-01
PL201215B1 (pl) 2009-03-31
IL147682A (en) 2006-12-10
WO2001006982A3 (fr) 2001-04-12
US20130039982A1 (en) 2013-02-14
NZ516726A (en) 2004-06-25
WO2001006982A2 (fr) 2001-02-01
CN1371276A (zh) 2002-09-25
DK1200071T3 (da) 2003-08-04
HRP20020165A2 (en) 2003-06-30
ZA200200380B (en) 2002-10-30
DE60002089T2 (de) 2004-02-05
JP4812211B2 (ja) 2011-11-09
FR2796840A1 (fr) 2001-02-02
CZ2002179A3 (cs) 2002-06-12
KR20020012638A (ko) 2002-02-16
DE60002089D1 (de) 2003-05-15
BG106342A (en) 2002-08-30
BG65535B1 (bg) 2008-11-28
TR200200198T2 (tr) 2002-09-23
EP1200071A2 (fr) 2002-05-02

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