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DE60129849D1 - Bioadhäsiver schaumstoffilm mit hinhaltender wirkstoffreigabe - Google Patents

Bioadhäsiver schaumstoffilm mit hinhaltender wirkstoffreigabe

Info

Publication number
DE60129849D1
DE60129849D1 DE60129849T DE60129849T DE60129849D1 DE 60129849 D1 DE60129849 D1 DE 60129849D1 DE 60129849 T DE60129849 T DE 60129849T DE 60129849 T DE60129849 T DE 60129849T DE 60129849 D1 DE60129849 D1 DE 60129849D1
Authority
DE
Germany
Prior art keywords
bioadhesive
stuff
foam
active ingredient
remaining active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60129849T
Other languages
English (en)
Other versions
DE60129849T2 (de
Inventor
Li-Lan H Chen
Li Tao
Alfred Liang
Xu Zheng
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lavipharm Laboratories Inc
Original Assignee
Lavipharm Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lavipharm Laboratories Inc filed Critical Lavipharm Laboratories Inc
Publication of DE60129849D1 publication Critical patent/DE60129849D1/de
Application granted granted Critical
Publication of DE60129849T2 publication Critical patent/DE60129849T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007Drug-containing films, membranes or sheets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30Oestrogens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60129849T 2000-11-15 2001-11-13 Bioadhäsiver schaumstoffilm mit hinhaltender wirkstoffreigabe Expired - Fee Related DE60129849T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US713548 2000-11-15
US09/713,548 US6756051B1 (en) 2000-11-15 2000-11-15 Bioadhesive, closed-cell foam film, sustained release, delivery devices and methods of making and using same
PCT/US2001/051252 WO2002056808A1 (en) 2000-11-15 2001-11-13 Bioadhesive cell foam film of sustained-release delivery

Publications (2)

Publication Number Publication Date
DE60129849D1 true DE60129849D1 (de) 2007-09-20
DE60129849T2 DE60129849T2 (de) 2008-04-24

Family

ID=24866569

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60129849T Expired - Fee Related DE60129849T2 (de) 2000-11-15 2001-11-13 Bioadhäsiver schaumstoffilm mit hinhaltender wirkstoffreigabe

Country Status (8)

Country Link
US (2) US6756051B1 (de)
EP (1) EP1357870B1 (de)
JP (1) JP2004535361A (de)
AT (1) ATE369125T1 (de)
AU (1) AU2002246916B2 (de)
DE (1) DE60129849T2 (de)
ES (1) ES2291377T3 (de)
WO (1) WO2002056808A1 (de)

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US6756051B1 (en) * 2000-11-15 2004-06-29 Li-Lan H. Chen Bioadhesive, closed-cell foam film, sustained release, delivery devices and methods of making and using same
US20030219479A1 (en) * 2002-04-08 2003-11-27 Lavipharm Laboratories Inc. Multi-layer mucoadhesive drug delivery device with bursting release layer
US7306812B2 (en) * 2003-05-09 2007-12-11 Cephalon, Inc. Dissolvable backing layer for use with a transmucosal delivery device
US20110150974A1 (en) * 2004-08-06 2011-06-23 Daiichi Pharmaceutical Co., Ltd. Agent For Oral Mucosal Administration
WO2006051819A1 (ja) 2004-11-10 2006-05-18 Hisamitsu Pharmaceutical Co., Inc. 外用製剤及び貼付剤
WO2006051818A1 (ja) * 2004-11-10 2006-05-18 Hisamitsu Pharmaceutical Co., Inc. 外用製剤及び貼付剤
WO2006078998A2 (en) 2005-01-19 2006-07-27 Neurohealing Pharmaceuticals, Inc. Methods and compositions for decreasing saliva production
CA2598445A1 (en) * 2005-02-22 2006-08-31 Tim T. Nguyen Method for treatment of onychomycosis
US20080248090A1 (en) * 2005-05-09 2008-10-09 Sunnen Gerard V Graduated concentration sodium chloride patches for the treatment of dental conditions
US20060252010A1 (en) * 2005-05-09 2006-11-09 Sunnen Gerard V Sodium chloride pad for treatment of dental conditions
US20090123545A1 (en) * 2005-07-21 2009-05-14 Ron Eyal S Rapid Onset and Short Term Modafinil Compositions and Methods of Use Thereof
US8367126B2 (en) 2005-09-27 2013-02-05 University Of Kentucky Research Foundation Berry preparations and extracts
EP1928250A4 (de) * 2005-09-27 2010-04-28 Univ Kentucky Res Found Beerenzubereitungen und extrakte
US8021696B2 (en) 2006-06-20 2011-09-20 Izun Pharmaceuticals Corporation Anti-inflammatory dissolvable film
JP5395663B2 (ja) * 2006-08-14 2014-01-22 ニューロヒーリング・ファーマシューティカルズ・インコーポレーテッド モダフィニルによる早漏の治療
WO2008027037A1 (en) * 2006-08-29 2008-03-06 University Of Kentucky Research Foundation Compositions and methods for oral cancer chemoprevention using berry preparations and extracts
US8603138B2 (en) 2006-10-04 2013-12-10 Ethicon Endo-Surgery, Inc. Use of an adhesive to treat intraluminal bleeding
US7914511B2 (en) 2006-10-18 2011-03-29 Ethicon Endo-Surgery, Inc. Use of biosurgical adhesive as bulking agent
US7441973B2 (en) 2006-10-20 2008-10-28 Ethicon Endo-Surgery, Inc. Adhesive applicator
US7749235B2 (en) 2006-10-20 2010-07-06 Ethicon Endo-Surgery, Inc. Stomach invagination method and apparatus
US7658305B2 (en) 2006-10-25 2010-02-09 Ethicon Endo-Surgery, Inc. Adhesive applier with articulating tip
US8876844B2 (en) 2006-11-01 2014-11-04 Ethicon Endo-Surgery, Inc. Anastomosis reinforcement using biosurgical adhesive and device
US7892250B2 (en) 2006-11-01 2011-02-22 Ethicon Endo-Surgery, Inc. Use of biosurgical adhesive on inflatable device for gastric restriction
US7833216B2 (en) 2006-11-08 2010-11-16 Ethicon Endo-Surgery, Inc. Fluid plunger adhesive dispenser
WO2008073779A2 (en) * 2006-12-07 2008-06-19 Drugtech Corporation Compositions and methods for treating seizures
PL2952191T3 (pl) 2009-06-12 2019-02-28 Sunovion Pharmaceuticals Inc. Apomorfina w postaci do podawania podjęzykowego
US8701671B2 (en) 2011-02-04 2014-04-22 Joseph E. Kovarik Non-surgical method and system for reducing snoring
US9549842B2 (en) 2011-02-04 2017-01-24 Joseph E. Kovarik Buccal bioadhesive strip and method of treating snoring and sleep apnea
US8608642B2 (en) 2010-02-25 2013-12-17 Ethicon Endo-Surgery, Inc. Methods and devices for treating morbid obesity using hydrogel
CN103476372B (zh) 2010-12-16 2016-04-27 Cynapsus疗法有限公司 舌下薄膜
US11998479B2 (en) 2011-02-04 2024-06-04 Seed Health, Inc. Method and system for addressing adverse effects on the oral microbiome and restoring gingival health caused by sodium lauryl sulphate exposure
US10085938B2 (en) 2011-02-04 2018-10-02 Joseph E. Kovarik Method and system for preventing sore throat in humans
US11357722B2 (en) 2011-02-04 2022-06-14 Seed Health, Inc. Method and system for preventing sore throat in humans
US12279989B2 (en) 2011-02-04 2025-04-22 Seed Health, Inc. Method and system for increasing beneficial bacteria and decreasing pathogenic bacteria in the oral cavity
US11951139B2 (en) 2015-11-30 2024-04-09 Seed Health, Inc. Method and system for reducing the likelihood of osteoporosis
US12257272B2 (en) 2015-12-24 2025-03-25 Seed Health, Inc. Method and system for reducing the likelihood of developing depression in an individual
US11844720B2 (en) 2011-02-04 2023-12-19 Seed Health, Inc. Method and system to reduce the likelihood of dental caries and halitosis
US11951140B2 (en) 2011-02-04 2024-04-09 Seed Health, Inc. Modulation of an individual's gut microbiome to address osteoporosis and bone disease
US11998574B2 (en) 2013-12-20 2024-06-04 Seed Health, Inc. Method and system for modulating an individual's skin microbiome
US11833177B2 (en) 2013-12-20 2023-12-05 Seed Health, Inc. Probiotic to enhance an individual's skin microbiome
US11839632B2 (en) 2013-12-20 2023-12-12 Seed Health, Inc. Topical application of CRISPR-modified bacteria to treat acne vulgaris
US12005085B2 (en) 2013-12-20 2024-06-11 Seed Health, Inc. Probiotic method and composition for maintaining a healthy vaginal microbiome
US11826388B2 (en) 2013-12-20 2023-11-28 Seed Health, Inc. Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation
US11980643B2 (en) 2013-12-20 2024-05-14 Seed Health, Inc. Method and system to modify an individual's gut-brain axis to provide neurocognitive protection
US11969445B2 (en) 2013-12-20 2024-04-30 Seed Health, Inc. Probiotic composition and method for controlling excess weight, obesity, NAFLD and NASH
US12329783B2 (en) 2013-12-20 2025-06-17 Seed Health, Inc. Method and system to improve the health of a person's skin microbiome
US12246043B2 (en) 2013-12-20 2025-03-11 Seed Health, Inc. Topical application to treat acne vulgaris
ES3015535T3 (en) 2015-04-21 2025-05-06 Sumitomo Pharma America Inc Methods of treating parkinson's disease by administration of apomorphine to an oral mucosa
JP7035006B2 (ja) * 2016-07-08 2022-03-14 セルテック アーベー 多孔性固体材料がクローズドセルを含む、セルロースナノファイバー(cnf)を含む多孔性固体材料の薬物担体
DE102021100780A1 (de) 2021-01-15 2022-07-21 Lts Lohmann Therapie-Systeme Ag. Oraler dünnfilm mit pva-tris-pufferschicht

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JPS5758615A (en) * 1980-09-26 1982-04-08 Nippon Soda Co Ltd Film agnent and its preparation
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EP0159604B1 (de) * 1984-04-09 1990-11-07 Toyo Boseki Kabushiki Kaisha Präparat mit verzögerter Freigabe zum Aufbringen auf die Schleimhäute der Mundhöhle
US4629621A (en) 1984-07-23 1986-12-16 Zetachron, Inc. Erodible matrix for sustained release bioactive composition
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US4772470A (en) 1985-04-27 1988-09-20 Nitto Electric Industrial Co., Ltd. Oral bandage and oral preparations
JPS61280423A (ja) 1985-06-05 1986-12-11 Kiyuukiyuu Yakuhin Kogyo Kk 口腔内粘膜貼付剤
JPH0729915B2 (ja) 1986-02-01 1995-04-05 帝國製薬株式会社 シ−ト状口腔内貼付剤
CA1302280C (en) * 1986-04-21 1992-06-02 Jon Joseph Kabara Topical antimicrobial pharmaceutical compositions and methods
US4713243A (en) 1986-06-16 1987-12-15 Johnson & Johnson Products, Inc. Bioadhesive extruded film for intra-oral drug delivery and process
US4900552A (en) 1988-03-30 1990-02-13 Watson Laboratories, Inc. Mucoadhesive buccal dosage forms
US5047244A (en) 1988-06-03 1991-09-10 Watson Laboratories, Inc. Mucoadhesive carrier for delivery of therapeutical agent
DE3827561C1 (de) 1988-08-13 1989-12-28 Lts Lohmann Therapie-Systeme Gmbh & Co Kg, 5450 Neuwied, De
JP2656338B2 (ja) 1989-01-31 1997-09-24 日東電工株式会社 口腔粘膜貼付製剤
DE4119140C2 (de) * 1991-06-11 1994-05-11 Merz & Co Gmbh & Co Poröser, in Körperflüssigkeiten und Sekreten löslicher, spongoider Formkörper, dessen Herstellung und Verwendung
CA2105887C (en) 1992-09-10 2004-03-16 Peter Britton Bioerodible device for administering active ingredients
US5458884A (en) 1992-09-10 1995-10-17 Britton; Peter Bioerodible device for administering active ingredients
US5346701A (en) 1993-02-22 1994-09-13 Theratech, Inc. Transmucosal delivery of macromolecular drugs
AU7568394A (en) 1993-08-19 1995-03-14 Cygnus Therapeutic Systems Water-soluble pressure-sensitive mucoadhesive and devices provided therewith for emplacement in a mucosa-lined body cavity
DE19503338C2 (de) * 1995-02-02 1998-07-30 Lohmann Therapie Syst Lts Arzneiform zur Abgabe von Kollagenase an Wunden und Verfahren zu ihrer Herstellung und ihre Verwendung
FR2742989B1 (fr) 1995-12-29 1998-01-23 Adir Composition pharmaceutique bioadhesive pour la liberation controlee de principes actifs
PL187242B1 (pl) 1996-05-13 2004-06-30 Novartis Consumer Health Sa Policzkowy układ dostarczający
US6650934B2 (en) * 1996-12-17 2003-11-18 Alza Corp Polymeric foam reservoirs for an electrotransport delivery device
EP1200519A1 (de) * 1999-07-06 2002-05-02 The Procter & Gamble Company Vorgeformte und selbstklebende folienmaterialien für topische anwendung
US6756051B1 (en) * 2000-11-15 2004-06-29 Li-Lan H. Chen Bioadhesive, closed-cell foam film, sustained release, delivery devices and methods of making and using same

Also Published As

Publication number Publication date
US6756051B1 (en) 2004-06-29
JP2004535361A (ja) 2004-11-25
ATE369125T1 (de) 2007-08-15
EP1357870B1 (de) 2007-08-08
US7138135B2 (en) 2006-11-21
EP1357870A1 (de) 2003-11-05
US20040234578A1 (en) 2004-11-25
AU2002246916B2 (en) 2006-06-08
EP1357870A4 (de) 2005-12-14
DE60129849T2 (de) 2008-04-24
ES2291377T3 (es) 2008-03-01
WO2002056808A1 (en) 2002-07-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee