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ES2188953T3 - Procedimiento para la preparacion de ftalidas. - Google Patents

Procedimiento para la preparacion de ftalidas.

Info

Publication number
ES2188953T3
ES2188953T3 ES97928217T ES97928217T ES2188953T3 ES 2188953 T3 ES2188953 T3 ES 2188953T3 ES 97928217 T ES97928217 T ES 97928217T ES 97928217 T ES97928217 T ES 97928217T ES 2188953 T3 ES2188953 T3 ES 2188953T3
Authority
ES
Spain
Prior art keywords
pct
ftalidas
procedure
preparation
phthalide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97928217T
Other languages
English (en)
Inventor
Klemens Massonne
Rainer Becker
Wolfgang Reif
Horst Neuhauser
Andreas Gieseler
Klaus Mundinger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Application granted granted Critical
Publication of ES2188953T3 publication Critical patent/ES2188953T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA PRESENTE INVENCION TRATA DE UN PROCEDIMIENTO PARA LA OBTENCION DE FTALUROS DE FORMULA GENERAL I, EN LA CUAL R 1 , R 2 , R 3 Y R 4 SON, INDEPENDIENTEMENTE UNO DEL OTRO, HIDROGENO, ALQUILO DE C 1 -C 4 O ALCOXI DE C SUB,1 -C 4 , MEDIANTE HIDROGENACION CATALITICA DE ANHIDRIDOS DE ACIDO FTALICO DE FORMULA GENERAL (II), EN LA CUAL LOS RADICALES R 1 , R 2 , R 3 Y R 4 TIENEN LOS SIGNIF ICADOS CITADOS ANTES, EN UN DISOLVENTE EN EL CUAL EL FTALURO (I), EL CUAL SE FORMA COMO PRODUCTO DE LA HIDROGENACION CATALITICA, SE UTILIZA COMO DISOLVENTE.
ES97928217T 1996-07-03 1997-06-17 Procedimiento para la preparacion de ftalidas. Expired - Lifetime ES2188953T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19626659A DE19626659A1 (de) 1996-07-03 1996-07-03 Verfahren zur Herstellung von Phthaliden

Publications (1)

Publication Number Publication Date
ES2188953T3 true ES2188953T3 (es) 2003-07-01

Family

ID=7798741

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97928217T Expired - Lifetime ES2188953T3 (es) 1996-07-03 1997-06-17 Procedimiento para la preparacion de ftalidas.

Country Status (11)

Country Link
US (1) US6028204A (es)
EP (1) EP0912540B1 (es)
JP (1) JP2000513726A (es)
CN (1) CN1075496C (es)
AT (1) ATE229517T1 (es)
DE (2) DE19626659A1 (es)
DK (1) DK0912540T3 (es)
ES (1) ES2188953T3 (es)
PT (1) PT912540E (es)
TW (1) TW455585B (es)
WO (1) WO1998001437A1 (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE230738T1 (de) 1998-10-20 2003-01-15 Lundbeck & Co As H Verfahren zur herstellung von citalopram
TR200101796T2 (tr) 1998-12-23 2001-11-21 H. Lundbeck A/S 5-Siyanofitalitin preparasyonuna yönelik metot
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
PL198024B1 (pl) * 1999-04-14 2008-05-30 Lundbeck & Co As H Sposób wytwarzania citalopramu, związki pośrednie i ich zastosowanie do wytwarzania citalopramu
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
PT1298124E (pt) 1999-10-25 2007-05-31 Lundbeck & Co As H Método para a preparação de citalopram
ES2169709A1 (es) 1999-10-25 2002-07-01 Lundbeck & Co As H Metodo para la preparacion de citalopram
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
CN1398263A (zh) 1999-12-28 2003-02-19 H·隆德贝克有限公司 制备西酞普兰的方法
PL198803B1 (pl) 1999-12-30 2008-07-31 Lundbeck & Co As H Sposób wytwarzania 5-cyjano-3H-izobenzofuran-1-onu
EP1254129B1 (en) * 2000-01-14 2003-10-22 H. Lundbeck A/S Method for the preparation of 5-cyanophthalide
NL1017415C1 (nl) 2000-02-24 2001-05-18 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
IES20010157A2 (en) 2000-03-03 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
JP2003527387A (ja) * 2000-03-13 2003-09-16 ハー・ルンドベック・アクチエゼルスカベット シタロプラムの製造方法
CN1427835A (zh) * 2000-03-13 2003-07-02 H·隆德贝克有限公司 5－取代的1－(4－氟苯基)－1,3－二氢异苯并呋喃的分步烷基化
IES20010206A2 (en) 2000-03-13 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
DK1265882T3 (da) 2000-03-14 2004-06-01 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
KR20020080483A (ko) * 2000-03-16 2002-10-23 하. 룬트벡 아크티에 셀스카브 5-시아노-1-(4-플루오로페닐)-1,3-디히드로이소벤조푸란의제조 방법
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
CN1182127C (zh) * 2000-06-28 2004-12-29 中国医学科学院药物研究所 新的取代的2-苯并[c]呋喃酮化合物,其制备方法以及包含它们的药物组合物
IL144817A0 (en) 2000-08-18 2002-06-30 Lundbeck & Co As H Method for the preparation of citalopram
SG167655A1 (en) 2000-12-22 2011-01-28 Lundbeck & Co As H Method for the preparation of pure citalopram
HRP20020005A2 (en) * 2000-12-28 2003-04-30 Lundbeck & Co As H Process for the preparation of pure citalopram
WO2004089924A1 (en) * 2003-04-11 2004-10-21 Bromine Compounds Ltd. Process for the preparation of 5-bromophthalide
CN101302209B (zh) * 2008-06-13 2011-05-04 浙江工业大学 一种金基催化剂作用下苯酐液相加氢制备苯酞的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2079325A (en) * 1935-03-30 1937-05-04 Du Pont Process for the preparation of lactones
US2114696A (en) * 1935-03-30 1938-04-19 Du Pont Process of producing phthalide
DE2803319C2 (de) * 1978-01-26 1986-11-13 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von Phthalid
DE3201300A1 (de) * 1982-01-18 1983-07-28 Dynamit Nobel Ag, 5210 Troisdorf Verfahren zur herstellung von phthalid
DE4136992A1 (de) * 1991-11-11 1993-05-13 Basf Ag Verfahren zur herstellung von phthaliden

Also Published As

Publication number Publication date
DE59708958D1 (de) 2003-01-23
EP0912540A1 (de) 1999-05-06
CN1216987A (zh) 1999-05-19
WO1998001437A1 (de) 1998-01-15
DE19626659A1 (de) 1998-01-08
JP2000513726A (ja) 2000-10-17
EP0912540B1 (de) 2002-12-11
TW455585B (en) 2001-09-21
CN1075496C (zh) 2001-11-28
DK0912540T3 (da) 2003-01-06
ATE229517T1 (de) 2002-12-15
PT912540E (pt) 2003-04-30
US6028204A (en) 2000-02-22

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