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ES2179052T3 - Composicion farmaceutica que contiene un derivado de ciclosporina. - Google Patents

Composicion farmaceutica que contiene un derivado de ciclosporina.

Info

Publication number
ES2179052T3
ES2179052T3 ES93911768T ES93911768T ES2179052T3 ES 2179052 T3 ES2179052 T3 ES 2179052T3 ES 93911768 T ES93911768 T ES 93911768T ES 93911768 T ES93911768 T ES 93911768T ES 2179052 T3 ES2179052 T3 ES 2179052T3
Authority
ES
Spain
Prior art keywords
composition containing
pharmaceutical composition
cyclosporine derivative
composition
microemulsion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93911768T
Other languages
English (en)
Inventor
Armin Meinzer
Friedrich Richter
Jacky Francis Vonderscher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Application granted granted Critical
Publication of ES2179052T3 publication Critical patent/ES2179052T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)

Abstract

UNA COMPOSICION FARMACEUTICA CONTENIENDO ([3'' 3'' ACTIVO. LA COMPOSICION SE FORMULA COMO UNA MICROEMULSION O PRECONCENTRADO DE MICROEMULSION, USANDO UN MEDIO SOPORTE, COMPRENDIENDO UNA FASE HIDROFILICA; UN ACEITE VEGETAL ETOXILATADO TRANSESTERIFICADO; Y UN SURFACTANTE. LA COMPOSICION TIENE BUENAS PROPIEDADES DE ESTABILIDAD Y FARMACEUTICAS, Y ES UTIL EN EL TRATAMIENTO DE SINDROME DE RESISTENCIA A MULTIPLES MEDICINAS EN SERES HUMANOS.
ES93911768T 1992-04-22 1993-04-20 Composicion farmaceutica que contiene un derivado de ciclosporina. Expired - Lifetime ES2179052T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929208712A GB9208712D0 (en) 1992-04-22 1992-04-22 Pharmaceutical compositions containing cyclosporin derivates

Publications (1)

Publication Number Publication Date
ES2179052T3 true ES2179052T3 (es) 2003-01-16

Family

ID=10714386

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93911768T Expired - Lifetime ES2179052T3 (es) 1992-04-22 1993-04-20 Composicion farmaceutica que contiene un derivado de ciclosporina.

Country Status (22)

Country Link
EP (1) EP0637248B1 (es)
JP (1) JP2818298B2 (es)
KR (2) KR950701227A (es)
AT (1) ATE219940T1 (es)
AU (1) AU672793B2 (es)
CA (1) CA2132740C (es)
CY (1) CY2399B1 (es)
CZ (1) CZ287359B6 (es)
DE (1) DE69332078T2 (es)
DK (1) DK0637248T3 (es)
ES (1) ES2179052T3 (es)
FI (1) FI111130B (es)
GB (1) GB9208712D0 (es)
HU (1) HU218279B (es)
NO (1) NO315075B1 (es)
NZ (1) NZ252681A (es)
PT (1) PT637248E (es)
RU (1) RU2126263C1 (es)
SG (1) SG50692A1 (es)
SK (1) SK282745B6 (es)
UA (1) UA34454C2 (es)
WO (1) WO1993020833A1 (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6007840A (en) * 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
KR0148748B1 (ko) 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
HK1004520A1 (en) 1992-05-13 1998-11-27 Novartis Ag Ophthalmic compositions containing a cyclosporin
EP0589843B1 (en) 1992-09-25 2001-11-28 Novartis AG Pharmaceutical compositions containing cyclosporins
CH686761A5 (de) * 1993-05-27 1996-06-28 Sandoz Ag Galenische Formulierungen.
GB2278780B (en) * 1993-05-27 1998-10-14 Sandoz Ltd Macrolide formulations
GB2315216B (en) * 1993-10-05 1998-10-14 Ciba Geigy Ag Microemulsion preconcentrates comprising FK506 or 33-epi-chloro-33-desoxy-ascomycin
DE59510233D1 (de) 1994-11-03 2002-07-11 Novartis Ag Neue zubereitungsformen des cyclosporins zur oralen applikation mit einfacher zusammensetzung und hoher bioverfügbarkeit und verfahren zu deren herstellung
HU215966B (hu) * 1994-11-21 1999-07-28 BIOGAL Gyógyszergyár Rt. Orálisan alkalmazható, ciklosporint tartalmazó, összetett emulzió-előkoncentrátum
US5766629A (en) 1995-08-25 1998-06-16 Sangstat Medical Corporation Oral cyclosporin formulations
US5962019A (en) * 1995-08-25 1999-10-05 Sangstat Medical Corporation Oral cyclosporin formulations
DE19549852B4 (de) 1995-11-29 2009-06-04 Novartis Ag Cyclosporin enthaltende Präparate
GB9601120D0 (en) * 1996-01-19 1996-03-20 Sandoz Ltd Organic compounds
HU223054B1 (hu) * 1997-03-25 2004-03-01 BIOGAL Gyógyszergyár Rt. Tisztítási eljárás nagytisztaságú ciklosporin A előállítására
EP0989851B1 (en) * 1997-07-29 2002-10-02 PHARMACIA & UPJOHN COMPANY Self-emulsifying formulation for acidic lipophilic compounds
NZ502569A (en) * 1997-07-29 2002-05-31 Upjohn Co Self-emulsifying formulation for lipophilic compounds comprising a mixture of diglyceride and monoglyceride in a ratio of 9:1 to 6:4
US6346511B1 (en) 1997-09-08 2002-02-12 Panacea Biotec Limited Pharmaceutical composition comprising cyclosporin
US6187747B1 (en) 1997-09-08 2001-02-13 Panacea Biotech Limited Pharmaceutical composition comprising cyclosporin
US6008191A (en) * 1997-09-08 1999-12-28 Panacea Biotec Limited Pharmaceutical compositions containing cyclosporin
WO1999044594A1 (fr) * 1998-03-05 1999-09-10 Nippon Shinyaku Co., Ltd. Emulsions huileuses destinees a etre administrees par inhalation
US6294192B1 (en) * 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
HUP0400263A2 (hu) 2001-06-21 2005-03-29 Pfizer Products Inc. Koleszteril-észter transzfer protein inhibitort tartalmazó önemulgeáló készítmény
PT1435910E (pt) * 2001-10-19 2009-09-07 Isotechnika Inc Novos pré-concentrados de microemulsão de análogos da ciclosporina
US6828301B2 (en) 2002-02-07 2004-12-07 Boehringer Ingelheim International Gmbh Pharmaceutical compositions for hepatitis C viral protease inhibitors
RU2293763C2 (ru) * 2005-05-18 2007-02-20 Государственное учреждение Научно-исследовательский институт вакцин и сывороток им. И.И. Мечникова Российской академии медицинских наук (ГУ НИИВС им. И.И. Мечникова РАМН) Способ получения акарицидно-моющего средства для борьбы с клещами
RU2294959C2 (ru) * 2005-05-18 2007-03-10 Общество с ограниченной ответственностью "Карат" (ООО "Карат") Способ получения акарицидно-моющего средства для борьбы с клещами
RU2320365C2 (ru) * 2005-09-15 2008-03-27 Григорьев Лев Викторович Фармацевтическая композиция
EP2204167A1 (en) 2009-01-05 2010-07-07 Azad Pharma AG Pharmaceutical microemulsion for preventing supramolecular aggregation of amphiphilic molecules
PL2451438T3 (pl) 2009-07-07 2014-07-31 Boehringer Ingelheim Int Kompozycja farmaceutyczna inhibitora proteazy wirusowego zapalenia wątroby typu C

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2907460A1 (de) * 1978-03-07 1979-09-13 Sandoz Ag Neue resorbierbare galenische kompositionen
EP0296122B1 (en) * 1987-06-17 1993-09-29 Sandoz Ag Cyclosporins and their use as pharmaceuticals
DD283404A5 (de) * 1987-12-21 1990-10-10 Sandoz A. G.,Ch Verfahren zur herstellung von ciclosporin in nichtsolvatisiertr orthonombischer kristallform
KR0148748B1 (ko) * 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물

Also Published As

Publication number Publication date
FI944978L (fi) 1994-10-21
DE69332078D1 (de) 2002-08-08
EP0637248B1 (en) 2002-07-03
JP2818298B2 (ja) 1998-10-30
DE69332078T2 (de) 2002-12-19
HU218279B (en) 2000-07-28
SK127294A3 (en) 1995-04-12
NO943998L (no) 1994-10-21
EP0637248A1 (en) 1995-02-08
WO1993020833A1 (en) 1993-10-28
HU9403055D0 (en) 1994-12-28
AU4261193A (en) 1993-11-18
CA2132740C (en) 2008-01-15
CA2132740A1 (en) 1993-10-28
FI944978A0 (fi) 1994-10-21
HUT71580A (en) 1995-12-28
RU94046413A (ru) 1996-11-10
GB9208712D0 (en) 1992-06-10
SK282745B6 (sk) 2002-12-03
NO943998D0 (no) 1994-10-21
NO315075B1 (no) 2003-07-07
JPH07505872A (ja) 1995-06-29
UA34454C2 (uk) 2001-03-15
CY2399B1 (en) 2004-09-10
DK0637248T3 (da) 2002-10-28
KR100414853B1 (es) 2004-01-13
AU672793B2 (en) 1996-10-17
CZ287359B6 (en) 2000-11-15
KR950701227A (ko) 1995-03-23
ATE219940T1 (de) 2002-07-15
CZ261794A3 (en) 1995-02-15
PT637248E (pt) 2002-11-29
FI111130B (fi) 2003-06-13
SG50692A1 (en) 1999-05-25
RU2126263C1 (ru) 1999-02-20
NZ252681A (en) 1996-02-27

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