ES2163844T3 - Nuevos derivados de benceno-sulfonil-amina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. - Google Patents
Nuevos derivados de benceno-sulfonil-amina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.Info
- Publication number
- ES2163844T3 ES2163844T3 ES98400468T ES98400468T ES2163844T3 ES 2163844 T3 ES2163844 T3 ES 2163844T3 ES 98400468 T ES98400468 T ES 98400468T ES 98400468 T ES98400468 T ES 98400468T ES 2163844 T3 ES2163844 T3 ES 2163844T3
- Authority
- ES
- Spain
- Prior art keywords
- group
- rent
- hydrogen atom
- atom
- substituted case
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- YZCKVEUIGOORGS-UHFFFAOYSA-N Hydrogen atom Chemical compound [H] YZCKVEUIGOORGS-UHFFFAOYSA-N 0.000 abstract 5
- -1 AMINO Chemical class 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical class [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical class [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical class [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C381/00—Compounds containing carbon and sulfur and having functional groups not covered by groups C07C301/00 - C07C337/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Abstract
LA INVENCION SE REFIERE A UN COMPUESTO DE FORMULA (I): DONDE: R A , R B , IDENTICOS O DIFERENTES, REPRESENTAN UN ATOMO DE HIDROGENO O UN GRUPO ALQUILO, O BIEN R A , R SUB,B FORMAN JUNTOS UN ENLACE; R C REPRESENTA UN GRUPO HIDR OXI, ALCOXI EN SU CASO SUSTITUIDO, O AMINO EN SU CASO SUSTITUIDO; R 1 REPRESENTA UN ATOMO DE HIDROGENO O UN GRUPO - O N O 2 , - O - NO O - S - NO; R 2 , R 3 , IDENTICOS O DIFERENTES, REPRESENTAN UN ATOMO DE HIDROGENO O UN GRUPO ALQUILO O FENILO EN SU CASO SUSTITUIDO; X REPRESENTA UN ATOMO DE OXIGENO O UN GRUPO - NH - CO -, M REPRESENTA 0 O 1; N REPRESENTA UN NUMERO ENTERO COMO 0 N 6; P REPRESENTA 0 O 1; R 4 REPRESENTA UN ATOMO DE HIDROGENO, UN GRUPO ALQUILO EN SU CASO SUSTITUIDO, FENILO EN SU CASO SUSTITUIDO O UN GRUPO TAL COMO SE DEFINE EN LA DESCRIPCION; R 5 REPRESENTA UN ATOMO DE HIDROG ENO O UN GRUPO ALQUILO; R 6 REPRESENTA UN ATOMO DE HIDROGENO O UN GRUPO ALQUILO; O BIEN R 5 Y R 6 FORMAN JUNT OS UNA CADENA (CH 2 ) T - EN LA QUE T ES 1 O 2; Q REPRESENTA 0, 1 O 2;R REPRESENTA UN NUMERO ENTERO COMO 0 R 6; R SUB,D , R E , IDENTICOS O DIFERENTES, REPRESENTAN UN ATOMO DE HIDROGENO, DE HALOGENO, UN GRUPO ALQUILO, ALKOXI, HIDROXI O TRIHALOGENOALQUILO, QUEDANDO ENTENDIDO QUE AL MENOS UN GRUPO O - NO 2 , - O NO O - S - NO ESTE PRESENTE EN R 1 , R SUB,4 O R C , SUS ISOMEROS Y SUS SALES DE ADICION A UN ACIDO O UNA BASE FARMACEUTICAMENTE ACEPTABLE.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9702445A FR2760235B1 (fr) | 1997-02-28 | 1997-02-28 | Nouveaux derives de benzenesulfonylamine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2163844T3 true ES2163844T3 (es) | 2002-02-01 |
Family
ID=9504314
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES98400468T Expired - Lifetime ES2163844T3 (es) | 1997-02-28 | 1998-02-27 | Nuevos derivados de benceno-sulfonil-amina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6013667A (es) |
| EP (1) | EP0864561B1 (es) |
| JP (1) | JP3917287B2 (es) |
| CN (1) | CN1160323C (es) |
| AT (1) | ATE205189T1 (es) |
| AU (1) | AU736532B2 (es) |
| BR (1) | BR9800773A (es) |
| CA (1) | CA2231026C (es) |
| DE (1) | DE69801535T2 (es) |
| DK (1) | DK0864561T3 (es) |
| ES (1) | ES2163844T3 (es) |
| FR (1) | FR2760235B1 (es) |
| GR (1) | GR3037048T3 (es) |
| HU (1) | HU224960B1 (es) |
| NO (1) | NO310068B1 (es) |
| NZ (1) | NZ329868A (es) |
| PL (1) | PL193930B1 (es) |
| PT (1) | PT864561E (es) |
| ZA (1) | ZA981681B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2803848B1 (fr) * | 2000-01-19 | 2002-02-15 | Adir | Nouveaux derives de benzenesulfonamide, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2827280B1 (fr) * | 2001-07-13 | 2003-10-31 | Servier Lab | Nouveaux derives de benzene sulfonamide, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| US8152693B2 (en) | 2006-05-08 | 2012-04-10 | Nokia Corporation | Exercise data device, server, system and method |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3000377A1 (de) * | 1980-01-07 | 1981-07-09 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue sulfonamide, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel |
| US5409956A (en) * | 1991-03-01 | 1995-04-25 | Zeria Pharmaceutical Co., Ltd. | Indan derivative and thromboxane antagonist containing the same |
| EP0670833A1 (de) * | 1992-11-27 | 1995-09-13 | Iovis Biomedical And Pharmaceutical Consultants | Nitroxyverbindungen mit pharmazeutischen eigenschaften |
| FR2711139B1 (fr) * | 1993-10-15 | 1995-12-01 | Adir | Nouveaux dérivés de 1,2,3,4-tétrahydronaphtalène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
-
1997
- 1997-02-28 FR FR9702445A patent/FR2760235B1/fr not_active Expired - Fee Related
-
1998
- 1998-02-26 CA CA002231026A patent/CA2231026C/fr not_active Expired - Fee Related
- 1998-02-26 BR BR9800773-4A patent/BR9800773A/pt active Search and Examination
- 1998-02-26 JP JP04479498A patent/JP3917287B2/ja not_active Expired - Fee Related
- 1998-02-27 ES ES98400468T patent/ES2163844T3/es not_active Expired - Lifetime
- 1998-02-27 DK DK98400468T patent/DK0864561T3/da active
- 1998-02-27 US US09/032,587 patent/US6013667A/en not_active Expired - Lifetime
- 1998-02-27 ZA ZA981681A patent/ZA981681B/xx unknown
- 1998-02-27 AT AT98400468T patent/ATE205189T1/de active
- 1998-02-27 PL PL325082A patent/PL193930B1/pl not_active IP Right Cessation
- 1998-02-27 CN CNB981080707A patent/CN1160323C/zh not_active Expired - Fee Related
- 1998-02-27 HU HU9800430A patent/HU224960B1/hu not_active IP Right Cessation
- 1998-02-27 AU AU56360/98A patent/AU736532B2/en not_active Ceased
- 1998-02-27 NZ NZ329868A patent/NZ329868A/xx not_active IP Right Cessation
- 1998-02-27 EP EP98400468A patent/EP0864561B1/fr not_active Expired - Lifetime
- 1998-02-27 PT PT98400468T patent/PT864561E/pt unknown
- 1998-02-27 NO NO980842A patent/NO310068B1/no not_active IP Right Cessation
- 1998-02-27 DE DE69801535T patent/DE69801535T2/de not_active Expired - Lifetime
-
2001
- 2001-10-30 GR GR20010401920T patent/GR3037048T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP3917287B2 (ja) | 2007-05-23 |
| CA2231026A1 (fr) | 1998-08-28 |
| AU5636098A (en) | 1998-09-03 |
| HUP9800430A2 (hu) | 1999-06-28 |
| DE69801535D1 (de) | 2001-10-11 |
| ATE205189T1 (de) | 2001-09-15 |
| JPH10251217A (ja) | 1998-09-22 |
| PT864561E (pt) | 2001-12-28 |
| HU224960B1 (en) | 2006-04-28 |
| NO980842L (no) | 1998-08-31 |
| BR9800773A (pt) | 1999-12-07 |
| US6013667A (en) | 2000-01-11 |
| CN1160323C (zh) | 2004-08-04 |
| DE69801535T2 (de) | 2002-05-08 |
| NO980842D0 (no) | 1998-02-27 |
| HK1014932A1 (en) | 1999-10-08 |
| CN1195662A (zh) | 1998-10-14 |
| FR2760235B1 (fr) | 1999-04-09 |
| NO310068B1 (no) | 2001-05-14 |
| PL325082A1 (en) | 1998-08-31 |
| HUP9800430A3 (en) | 2000-09-28 |
| EP0864561A1 (fr) | 1998-09-16 |
| GR3037048T3 (en) | 2002-01-31 |
| AU736532B2 (en) | 2001-08-02 |
| FR2760235A1 (fr) | 1998-09-04 |
| NZ329868A (en) | 1999-01-28 |
| ZA981681B (en) | 1998-09-04 |
| DK0864561T3 (da) | 2001-11-19 |
| PL193930B1 (pl) | 2007-04-30 |
| CA2231026C (fr) | 2004-02-10 |
| HU9800430D0 (en) | 1998-04-28 |
| EP0864561B1 (fr) | 2001-09-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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