[go: up one dir, main page]

ES2149951T3 - Producto pseudodipeptido que posee un grupo imidazol y aplicaciones del mismo. - Google Patents

Producto pseudodipeptido que posee un grupo imidazol y aplicaciones del mismo.

Info

Publication number
ES2149951T3
ES2149951T3 ES95900185T ES95900185T ES2149951T3 ES 2149951 T3 ES2149951 T3 ES 2149951T3 ES 95900185 T ES95900185 T ES 95900185T ES 95900185 T ES95900185 T ES 95900185T ES 2149951 T3 ES2149951 T3 ES 2149951T3
Authority
ES
Spain
Prior art keywords
radical
fluoroalkyl
product
pseudodipeptido
applications
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95900185T
Other languages
English (en)
Inventor
Marc Babizhayev
Marie-Christine Seguin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Exsymol SAM
Original Assignee
Exsymol SAM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exsymol SAM filed Critical Exsymol SAM
Application granted granted Critical
Publication of ES2149951T3 publication Critical patent/ES2149951T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/522—Antioxidants; Radical scavengers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q13/00—Formulations or additives for perfume preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00—Anti-perspirants or body deodorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/004—Aftersun preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Ophthalmology & Optometry (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Dermatology (AREA)
  • Biotechnology (AREA)
  • Birds (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biophysics (AREA)
  • Transplantation (AREA)
  • Urology & Nephrology (AREA)

Abstract

PRODUCTO SEUDODIPEPTIDO DE FORMULA GENERAL (I) EN LA QUE A ES: A) BIEN LA FORMA A) DONDE B REPRESENTA UNA AMINA CUYO ATOMO DE NITROGENO DIRECTAMENTE UNIDO AL ATOMO DE CARBONO ES ELEGIDO ENTRE LAS AMINAS, LOS IMINOS Y LOS AMONIOS, R ES UN ATOMO DE FLUORURO, UN RADICAL FLUOROALQUILO, UN GRUPO FUNCIONAL, UN RADICAL ACILO, UNA CADENA ALQUILO LINEAL, O UN RADICAL ALQUENILO O ARILO, R'' ES UN ATOMO DE HIDROGENO, UN ATOMO DE FLUORURO, UN RADICAL ALQUILO, O UN RADICAL FLUOROALQUILO, Y IM ES UN NUCLEO IMIDAZOL O IMIDAZOL N-SUSTITUIDO, B) BIEN DE LA FORMA (B) DONDE R ES UN ATOMO DE HIDROGENO O UN RADICAL FLUOROALQUILO, ACILO O UN RADICAL HIDROCARBONADO QUE PUEDE SER SUSTITUIDO POR UNO O VARIOS GRUPOS FUNCIONALES,Y R'''' ES UN RADICAL HIDROCARBONADO O UN RADICAL ACILO.
ES95900185T 1993-11-05 1994-11-03 Producto pseudodipeptido que posee un grupo imidazol y aplicaciones del mismo. Expired - Lifetime ES2149951T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9313480A FR2711990B1 (fr) 1993-11-05 1993-11-05 Produit pseudodipeptide possédant un groupement imidazole, et applications thérapeutiques, cosmétologiques et agroalimentaires.

Publications (1)

Publication Number Publication Date
ES2149951T3 true ES2149951T3 (es) 2000-11-16

Family

ID=9452766

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95900185T Expired - Lifetime ES2149951T3 (es) 1993-11-05 1994-11-03 Producto pseudodipeptido que posee un grupo imidazol y aplicaciones del mismo.

Country Status (17)

Country Link
US (1) US6046340A (es)
EP (1) EP0726895B1 (es)
JP (1) JP3503899B2 (es)
KR (1) KR100363812B1 (es)
CN (1) CN1056608C (es)
BR (1) BR9407971A (es)
CA (1) CA2174526C (es)
CZ (1) CZ292108B6 (es)
DE (1) DE69425153T2 (es)
ES (1) ES2149951T3 (es)
FR (1) FR2711990B1 (es)
GR (1) GR3034543T3 (es)
HU (1) HU222566B1 (es)
PT (1) PT726895E (es)
RU (1) RU2159775C2 (es)
UA (1) UA56123C2 (es)
WO (1) WO1995012581A1 (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5786326A (en) * 1995-02-03 1998-07-28 Horwitz; Lawrence D. Method for the treatment of atherosclerosis and vascular injury by prevention of vascular smooth muscle cell proliferation
EP0841922B1 (en) * 1995-05-30 2002-02-20 Gliatech, Inc. 1h-4(5)-substituted imidazole derivatives
RU2141968C1 (ru) * 1997-07-04 1999-11-27 Небольсин Владимир Евгеньевич Способ получения гамма-l-глутамилгистамина, применение гамма-l-глутамилгистамина, фармацевтическая композиция
RU2141483C1 (ru) * 1997-07-04 1999-11-20 Небольсин Владимир Евгеньевич Производные пептидов или их фармацевтически приемлемые соли, способ их получения, применение и фармацевтическая композиция
FR2769838B1 (fr) * 1997-10-16 2000-04-07 Roc Sa Utilisation de derives d'azole pour la preparation d'une composition dermatologique ou cosmetologique
FR2778562B1 (fr) * 1998-05-14 2000-08-04 Sephra Composition pharmaceutique, hygienique et/ou cosmetique contenant de l'eau de mer et de l'arginine
JP2002520355A (ja) * 1998-07-14 2002-07-09 アルコン ラボラトリーズ， インコーポレイテッド 非アレルギー性眼炎症障害を処置および眼新生血管形成を予防する医薬製造のための、１１−（３−ジメチルアミノプロピリデン）−６，１１−ジヒドロジベンズ［ｂ，ｅ］オキセピン−２−酢酸の使用
US6417397B1 (en) 1999-10-04 2002-07-09 The Regents Of The University Of California, San Diego N-substituted alkylamino acids for use as amino-protecting groups
US6552010B1 (en) * 1999-11-12 2003-04-22 Genelabs Technologies, Inc. Treatment of SLE with dehydroepiandrosterone
EP1125925A1 (en) * 2000-02-15 2001-08-22 Applied Research Systems ARS Holding N.V. Amine derivatives for the treatment of apoptosis
DE60129008T2 (de) 2000-04-14 2007-10-11 Niadyne Corp., Tucson Methode zur identifizierung von regulatoren der bildung von protein-age-derivaten
WO2002069985A2 (en) * 2001-03-05 2002-09-12 Forinnova As Immune response potentiation
MC200060A1 (fr) * 2002-10-04 2003-05-28 M Exsymol Sa Produit de couplage entre la tryptamine et un alpha-aminoacide son procédé de préparation et son application dans le domaine de la neuro-cosmétique
WO2005011676A1 (es) * 2003-08-05 2005-02-10 Centro De Histoterapia Placentaria Composición para el tratamiento del vitíligo
EP2101834B1 (en) * 2006-12-01 2015-03-25 Wake Forest University Health Sciences Medical devices incorporating collagen inhibitors
MC200154A1 (fr) * 2012-07-02 2013-01-23 Exsymol Sa Famille de composés aryléthylamides polyaminés, et leurs applications cosmétiques ou dermocosmétiques
FR2992644B1 (fr) * 2012-07-02 2015-07-03 Exsymol Sa Famille de composes arylethylamides polyamines, et leurs applications cosmetiques ou dermocosmetiques
WO2014140890A2 (en) 2013-03-13 2014-09-18 Neocutis Sa Peptides for skin rejuvenation and methods of using the same
WO2015114176A1 (es) * 2014-01-31 2015-08-06 Dermopartners, S.L. Producto cosmético con propiedades contra el envejecimiento de la piel
CN116249522A (zh) * 2020-07-20 2023-06-09 深圳迈瑞生物医疗电子股份有限公司 一种组合物的血小板解聚用途、解聚试剂及解聚方法
CN114989091B (zh) * 2022-06-14 2025-03-21 水羊化妆品制造有限公司 一种谷氨酰胺基乙基咪唑的制备方法
FR3151760A1 (fr) * 2023-08-01 2025-02-07 Exsymol Nouvelles utilisations de dérivés imidazolyls
CN117143022B (zh) * 2023-08-30 2024-07-26 上海克琴科技有限公司 一种谷氨酰胺基乙基咪唑的合成方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2301532A (en) * 1938-08-18 1942-11-10 Parke Davis & Co Biological product and process of obtaining same
US2581814A (en) * 1947-10-04 1952-01-08 Ralph L Evans Preparation of glutamyl histidine
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
US4613676A (en) * 1983-11-23 1986-09-23 Ciba-Geigy Corporation Substituted 5-amino-4-hydroxyvaleryl derivatives
EP0144290A3 (de) * 1983-12-01 1987-05-27 Ciba-Geigy Ag Substituierte Aethylendiaminderivate
US4996221A (en) * 1987-01-13 1991-02-26 The Board Of Trustees Of The Leland Stanford Junior University Histamine derivatives as immune modulators
IL92441A (en) * 1988-12-07 1993-05-13 Tanabe Seiyaku Co Imidazole containing peptides, their preparation and pharmaceutical compositions containing them
US4962120A (en) * 1989-03-22 1990-10-09 Sterling Drug Inc. 1H-imidazole-1-acetamides
EP0473993B1 (en) * 1990-08-17 1996-04-17 Japan Tobacco Inc. Novel peptide derivatives and their pharmaceutical use
FR2701948B1 (fr) * 1993-02-22 1996-07-26 Exsymol Sa Produit de couplage de l'histamine ou l'histamine méthyl-substituée et d'un acide aminé, procédé de préparation et applications thérapeutiques, cosmétologiques et agroalimentaires.

Also Published As

Publication number Publication date
CA2174526C (fr) 2009-08-18
PT726895E (pt) 2000-12-29
KR960705785A (ko) 1996-11-08
RU2159775C2 (ru) 2000-11-27
DE69425153D1 (de) 2000-08-10
JPH09504540A (ja) 1997-05-06
CZ292108B6 (cs) 2003-07-16
HU9600989D0 (en) 1996-06-28
CN1056608C (zh) 2000-09-20
KR100363812B1 (ko) 2003-02-11
CN1136808A (zh) 1996-11-27
CA2174526A1 (fr) 1995-05-11
JP3503899B2 (ja) 2004-03-08
BR9407971A (pt) 1996-12-03
FR2711990B1 (fr) 1995-12-08
HUT74387A (en) 1996-12-30
EP0726895A1 (fr) 1996-08-21
EP0726895B1 (fr) 2000-07-05
CZ115596A3 (en) 1996-12-11
FR2711990A1 (fr) 1995-05-12
HU222566B1 (hu) 2003-08-28
WO1995012581A1 (fr) 1995-05-11
DE69425153T2 (de) 2001-03-15
GR3034543T3 (en) 2001-01-31
UA56123C2 (uk) 2003-05-15
US6046340A (en) 2000-04-04

Similar Documents

Publication Publication Date Title
ES2149951T3 (es) Producto pseudodipeptido que posee un grupo imidazol y aplicaciones del mismo.
MX9708988A (es) Agentes insecticidas.
DK249089A (da) Benzamid-forbindelser, der er nyttige som protease-inhibitorer
NO20031490D0 (no) Alifatisk nitrogenholdig 5-kantet ring-forbindelse
ES2053609T3 (es) Derivados de urea inhibidores de lipoxigenasa.
BR8600428A (pt) Compostos heterociclicos,processo para sua preparacao,composicoes inseticidas,processo para combate a insetos daninhos,utilizacao e processo para a preparacao de composicoes
HUP9802859A2 (hu) Acil-amino-szalicilsav-amid-származékok és alkalmazásuk peszticidként
DK0906907T3 (da) Forbindelser, der potenserer retinoid
ATE108187T1 (de) Protease-hemmer.
CY1109863T1 (el) Παραγωγα θειαζολης για χρηση ως αντιφλεγμονωδη
DE3776433D1 (de) Antimikrobielle mittel.
EP1650205A4 (en) cyclohexanecarboxylic
MX9700928A (es) Derivado de triazian y medicina que lo contiene.
NO943510D0 (no) Azolforbindelser, deres fremstilling og anvendelse
ES2086341T3 (es) Derivados de aminoacidos con propiedades inhibidoras de la renina, procedimiento para su preparacion, agentes que los contienen y su utilizacion.
EP1400513A4 (en) UNSYMMETRIC CYCLIC DIAMOND COMPOUND
ES2196721T3 (es) Metodo para producir un derivado de acido fenilpropionico opticamente activo.
FR2808678B1 (fr) Utilisation en cosmetique d'au moins un organopolysiloxane en tant que gelifiant et composition cosmetique le contenant
ES2113713T3 (es) Preparacion de tiamidas.
AR044175A1 (es) Compuestos de cefemo
ES2189736T3 (es) Derivados de la benzamida y medicamentos que los contienen.
ES8706110A1 (es) Un procedimiento para la preparacion de derivados de alfa-aminoalquil-alfa-alquilfenilacetonitrilo.
TR23309A (tr) Zararli mantar oeldueruecue anilin tuerevleri
ATE124683T1 (de) Derivate von aminsäuren.
ATE47135T1 (de) Antikonvulsive mittel.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 726895

Country of ref document: ES