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ES2146633T3 - Composicion medicamentosa de liberacion controlada. - Google Patents

Composicion medicamentosa de liberacion controlada.

Info

Publication number
ES2146633T3
ES2146633T3 ES94120709T ES94120709T ES2146633T3 ES 2146633 T3 ES2146633 T3 ES 2146633T3 ES 94120709 T ES94120709 T ES 94120709T ES 94120709 T ES94120709 T ES 94120709T ES 2146633 T3 ES2146633 T3 ES 2146633T3
Authority
ES
Spain
Prior art keywords
inner layer
drug formulation
water
drug
controlled release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94120709T
Other languages
English (en)
Inventor
Keiji Sumitomo Pharma Fujioka
Takeshi Hirasawa
Masako Kajihara
Akihiro Sano
Shuichi Sugawara
Yosuke Urabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DuPont Toray Specialty Materials KK
Sumitomo Pharma Co Ltd
Original Assignee
Sumitomo Pharmaceuticals Co Ltd
Dow Corning Asia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Pharmaceuticals Co Ltd, Dow Corning Asia Ltd filed Critical Sumitomo Pharmaceuticals Co Ltd
Application granted granted Critical
Publication of ES2146633T3 publication Critical patent/ES2146633T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nanotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)

Abstract

UNA FORMULA DE DROGA PARA PRODUCIR LA EFICACIA TERAPEUTICA CONTINUA, LA CUAL LIBERA LA DROGA SOLUBLE EN AGUA INTRACORPOREALMENTE DURANTE UN PERIODO PROLONGADO DE TIEMPO A UNA PROPORCION SUSTANCIALMENTE CONSTANTE EN DONDE DICHA FORMULA DE DROGA COMPRENDE: (A) UNA CAPA INTERIOR NO DESINTEGRANTE COMPRENDIDA DE UN MATERIAL BIOCOMPATIBLE QUE CONTIENE LA DROGA SOLUBLE EN AGUA DISPERSADA UNIFORMEMENTE; Y (B) UNA CAPA EXTERIOR COMPRENDIDA DE UN MATERIAL BIOCOMPATIBLE QUE RODEA LA CIRCUNFERENCIA DE LA DICHA CAPA INTERIOR, ES IMPERMEABLE AL AGUA, Y ES CAPAZ DE CONTROLAR LA HINCHAZON DE LA CAPA INTERIOR; EN DONDE LA PROPORCION DE LA LONGITUD AXIAL DE LA FORMULA DE DROGA AL DIAMETRO DE LA SECCION TRANSVERSAL DE LA CAPA INTERIOR ES UNO O MAS Y UNO O AMBOS EXTREMOS DE LA CAPA INTERIOR ESTAN ABIERTOS PARA ENTRAR EN CONTACTO DIRECTO CON EL AMBIENTE EXTERNO.
ES94120709T 1993-12-27 1994-12-27 Composicion medicamentosa de liberacion controlada. Expired - Lifetime ES2146633T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP33146793A JP3720386B2 (ja) 1993-12-27 1993-12-27 薬物放出制御製剤

Publications (1)

Publication Number Publication Date
ES2146633T3 true ES2146633T3 (es) 2000-08-16

Family

ID=18243976

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94120709T Expired - Lifetime ES2146633T3 (es) 1993-12-27 1994-12-27 Composicion medicamentosa de liberacion controlada.

Country Status (15)

Country Link
US (1) US5851547A (es)
EP (1) EP0659406B1 (es)
JP (1) JP3720386B2 (es)
KR (1) KR100349960B1 (es)
CN (1) CN1107497C (es)
AT (1) ATE190836T1 (es)
AU (1) AU686713B2 (es)
CA (1) CA2139058C (es)
DE (1) DE69423582T2 (es)
DK (1) DK0659406T3 (es)
ES (1) ES2146633T3 (es)
GR (1) GR3033248T3 (es)
NZ (1) NZ277548A (es)
PT (1) PT659406E (es)
WO (1) WO1995017881A1 (es)

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AUPR602401A0 (en) * 2001-06-29 2001-07-26 Smart Drug Systems Inc Sustained release delivery system
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AUPR951501A0 (en) * 2001-12-14 2002-01-24 Smart Drug Systems Inc Modified sustained release pharmaceutical system
US8454997B2 (en) 2001-12-18 2013-06-04 Novo Nordisk A/S Solid dose micro implant
CA2474292A1 (en) * 2002-01-24 2003-07-31 Smart Drug Systems Inc Sustained release pharmaceutical composition
JP4026745B2 (ja) * 2002-03-26 2007-12-26 財団法人大阪産業振興機構 医療用システムおよびその製造方法
US8871241B2 (en) 2002-05-07 2014-10-28 Psivida Us, Inc. Injectable sustained release delivery devices
US7736665B2 (en) 2002-05-31 2010-06-15 Titan Pharmaceuticals, Inc. Implantable polymeric device for sustained release of buprenorphine
SI1610791T1 (sl) 2003-03-31 2011-05-31 Titan Pharmaceuticals Inc Implantibilna polimerna naprava za zadržano sproščanje dopaminskega agonista
TWI336627B (en) * 2003-05-23 2011-02-01 Organon Nv Drug delivery system,and use and manufacturing method thereof
US20050031668A1 (en) * 2003-05-30 2005-02-10 Patel Rajesh A. Implantable polymeric device for sustained release of nalmefene
WO2005000278A1 (en) * 2003-06-26 2005-01-06 Mediolanum Pharmaceuticals Ltd. Subcutaneous implants having limited initial release of the active principle and subsequent linearly varying extended release thereof
EP1781264B1 (en) 2004-08-04 2013-07-24 Evonik Corporation Methods for manufacturing delivery devices and devices thereof
EP1968383B1 (en) * 2005-12-12 2011-05-11 Women and Infants Hospital of Rhode Island Derivatives of vitamin d and therapeutic use thereof
WO2008060360A2 (en) * 2006-09-28 2008-05-22 Surmodics, Inc. Implantable medical device with apertures for delivery of bioactive agents
US8252780B2 (en) * 2006-12-01 2012-08-28 Women & Infants' Hospital Organometallic complexes as therapeutic agents
US20080153906A1 (en) * 2006-12-13 2008-06-26 Celly Chander S Water-Soluble Phenicol Prodrugs in a Lipophilic Vehicle System
US8193180B2 (en) 2007-01-24 2012-06-05 Women & Infants Hospital N-amino tetrahydrothiazine derivatives, method of manufacture and use
AR066166A1 (es) * 2007-09-21 2009-07-29 Organon Nv Sistema de suministro de droga
EP2222281B1 (en) 2007-12-20 2018-12-05 Evonik Corporation Process for preparing microparticles having a low residual solvent volume
WO2010091234A2 (en) 2009-02-06 2010-08-12 The General Hospital Corporation Methods of treating vascular lesions
EP2246063A1 (en) 2009-04-29 2010-11-03 Ipsen Pharma S.A.S. Sustained release formulations comprising GnRH analogues
AU2010256558B2 (en) 2009-06-03 2013-10-03 Forsight Labs, Llc Anterior segment drug delivery
EP2601948A4 (en) 2010-08-06 2014-05-21 Dainippon Sumitomo Pharma Co PREPARATION FOR THE TREATMENT OF BACKBONE INJURIES
JP5898619B2 (ja) 2010-08-06 2016-04-06 大日本住友製薬株式会社 水溶性薬物放出制御製剤
AU2012308317B2 (en) 2011-09-14 2017-01-05 Forsight Vision5, Inc. Ocular insert apparatus and methods
SI2911623T1 (sl) 2012-10-26 2019-12-31 Forsight Vision5, Inc. Oftalmični sistem za podaljšano sproščanje zdravila v oko
HK1216240A1 (zh) 2012-11-14 2016-10-28 W. R. Grace & Co.-Conn. 含有生物活性材料与无序无机氧化物的组合物
US10596103B2 (en) 2013-12-11 2020-03-24 Merek Sharp & Dohme B.V. Drug delivery system for delivery of anti-virals
US10413504B2 (en) 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system
JP6359390B2 (ja) * 2014-09-05 2018-07-18 テルモ株式会社 インプラントデバイスおよびインプラントデバイス植え込み具
EP3283004A4 (en) 2015-04-13 2018-12-05 Forsight Vision5, Inc. Ocular insert composition of semi-crystalline or crystalline pharmaceutically active agent
CA3039051A1 (en) * 2016-10-05 2018-04-12 Titan Pharmaceuticals, Inc. Implantable devices for drug delivery with reduced burst release
AU2019294615A1 (en) * 2018-06-25 2021-02-11 ReacX Pharmaceuticals, Inc. Implants for release of lipophilic or amphiphilic pharmaceutical substances
KR102442807B1 (ko) * 2021-01-29 2022-09-15 주식회사 티온랩테라퓨틱스 초기 방출 제어된 데포 조성물 및 이의 제조방법

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NZ217844A (en) * 1985-10-11 1989-10-27 Sumitomo Pharma A sustained release pharmaceutical composition containing silicone elastomer and an albumin
JPS62174031A (ja) * 1985-10-11 1987-07-30 Sumitomo Pharmaceut Co Ltd 高分子量薬物含有徐放性製剤
IT1188212B (it) * 1985-12-20 1988-01-07 Paolo Colombo Sistema per il rilascio a velocita' controllata di sostanze attive
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US5322691A (en) * 1986-10-02 1994-06-21 Sohrab Darougar Ocular insert with anchoring protrusions
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JPH06321803A (ja) * 1993-05-17 1994-11-22 Kirin Brewery Co Ltd 水溶性ペプチドホルモンの徐放性製剤

Also Published As

Publication number Publication date
GR3033248T3 (en) 2000-09-29
JPH07187994A (ja) 1995-07-25
CA2139058A1 (en) 1995-06-28
EP0659406A3 (en) 1995-11-15
NZ277548A (en) 1997-05-26
US5851547A (en) 1998-12-22
ATE190836T1 (de) 2000-04-15
CA2139058C (en) 2004-11-16
EP0659406A2 (en) 1995-06-28
DE69423582D1 (de) 2000-04-27
AU1280995A (en) 1995-07-17
EP0659406B1 (en) 2000-03-22
CN1107497C (zh) 2003-05-07
DK0659406T3 (da) 2000-07-03
JP3720386B2 (ja) 2005-11-24
DE69423582T2 (de) 2000-09-07
WO1995017881A1 (en) 1995-07-06
PT659406E (pt) 2000-06-30
CN1142763A (zh) 1997-02-12
AU686713B2 (en) 1998-02-12
KR100349960B1 (ko) 2003-03-06

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