[go: up one dir, main page]

SI2911623T1 - Oftalmični sistem za podaljšano sproščanje zdravila v oko - Google Patents

Oftalmični sistem za podaljšano sproščanje zdravila v oko

Info

Publication number
SI2911623T1
SI2911623T1 SI201331615T SI201331615T SI2911623T1 SI 2911623 T1 SI2911623 T1 SI 2911623T1 SI 201331615 T SI201331615 T SI 201331615T SI 201331615 T SI201331615 T SI 201331615T SI 2911623 T1 SI2911623 T1 SI 2911623T1
Authority
SI
Slovenia
Prior art keywords
eye
drug
sustained release
ophthalmic system
ophthalmic
Prior art date
Application number
SI201331615T
Other languages
English (en)
Inventor
Anne Brody Rubin
Yair Alster
Cary J. Reich
Original Assignee
Forsight Vision5, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Forsight Vision5, Inc. filed Critical Forsight Vision5, Inc.
Publication of SI2911623T1 publication Critical patent/SI2911623T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067Means for introducing or releasing pharmaceutical products into the body
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T156/00Adhesive bonding and miscellaneous chemical manufacture
    • Y10T156/10Methods of surface bonding and/or assembly therefor
    • Y10T156/1002Methods of surface bonding and/or assembly therefor with permanent bending or reshaping or surface deformation of self sustaining lamina
    • Y10T156/1036Bending of one piece blank and joining edges to form article

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Prostheses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SI201331615T 2012-10-26 2013-10-25 Oftalmični sistem za podaljšano sproščanje zdravila v oko SI2911623T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261719144P 2012-10-26 2012-10-26
PCT/US2013/066834 WO2014066775A1 (en) 2012-10-26 2013-10-25 Ophthalmic system for sustained release of drug to eye
EP13786598.6A EP2911623B1 (en) 2012-10-26 2013-10-25 Ophthalmic system for sustained release of drug to eye

Publications (1)

Publication Number Publication Date
SI2911623T1 true SI2911623T1 (sl) 2019-12-31

Family

ID=49546644

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201331615T SI2911623T1 (sl) 2012-10-26 2013-10-25 Oftalmični sistem za podaljšano sproščanje zdravila v oko

Country Status (14)

Country Link
US (4) US9750636B2 (sl)
EP (1) EP2911623B1 (sl)
JP (1) JP6298068B2 (sl)
CN (1) CN104884006B (sl)
AU (1) AU2013334169B2 (sl)
CA (1) CA2888808C (sl)
DK (1) DK2911623T3 (sl)
ES (1) ES2752028T3 (sl)
HU (1) HUE046128T2 (sl)
PL (1) PL2911623T3 (sl)
PT (1) PT2911623T (sl)
RU (1) RU2652063C2 (sl)
SI (1) SI2911623T1 (sl)
WO (1) WO2014066775A1 (sl)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2623940C (en) 2005-09-27 2017-01-10 Tissuetech, Inc. Amniotic membrane preparations and purified compositions and methods of use
JP5695035B2 (ja) 2009-06-03 2015-04-01 フォーサイト・ビジョン5・インコーポレイテッドForsight Vision5,Inc. 前眼部薬物供給
SG187770A1 (en) 2010-08-12 2013-03-28 Univ Nanyang Tech A liposomal formulation for ocular drug delivery
ES2912370T3 (es) * 2011-09-14 2022-05-25 Forsight Vision5 Inc Aparato para inserción ocular
CN104884006B (zh) 2012-10-26 2017-12-15 弗赛特影像5股份有限公司 用于持续释放药物到眼睛的眼科系统
MX2015010771A (es) 2013-03-15 2016-06-24 Beaver Visitec Int Us Inc Expansor del iris.
US9956195B2 (en) 2014-01-07 2018-05-01 Nanyang Technological University Stable liposomal formulations for ocular drug delivery
WO2016138025A2 (en) 2015-02-23 2016-09-01 Tissuetech, Inc. Apparatuses and methods for treating ophthalmic diseases and disorders
WO2016168141A1 (en) 2015-04-13 2016-10-20 Forsight Vision5, Inc. Ocular insert composition of semi-crystalline or crystalline pharmaceutically active agent
US10987401B2 (en) * 2015-05-01 2021-04-27 Allysta Pharmaceuticals, Inc. Adiponectin peptidomimetics for treating ocular disorders
EP3340982B1 (en) 2015-08-26 2021-12-15 Achillion Pharmaceuticals, Inc. Compounds for treatment of immune and inflammatory disorders
AR106018A1 (es) 2015-08-26 2017-12-06 Achillion Pharmaceuticals Inc Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos
US11458041B2 (en) 2015-10-08 2022-10-04 Ocular Therapeutix, Inc. Punctal plug and bioadhesives
WO2017091749A1 (en) 2015-11-25 2017-06-01 Incept, Llc Shape changing drug delivery devices and methods
US10206814B2 (en) 2016-01-06 2019-02-19 David R. Hardten System and method for the delivery of medications or fluids to the eye
EP3455219A4 (en) 2016-05-10 2019-12-18 C4 Therapeutics, Inc. AMINE-RELATED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN REDUCTION
AU2017290593A1 (en) 2016-06-27 2019-01-03 Achillion Pharmaceuticals, Inc. Quinazoline and indole compounds to treat medical disorders
US12233017B2 (en) 2016-10-14 2025-02-25 Olympic Ophthalmics, Inc. Quiet handheld devices and methods for treatment of disorders
CN110603252A (zh) 2017-03-01 2019-12-20 艾其林医药公司 用于治疗医学障碍的芳基、杂芳基和杂环药物化合物
CN118440096A (zh) 2017-06-20 2024-08-06 C4医药公司 用于蛋白降解的n/o-连接的降解决定子和降解决定子体
US11147735B2 (en) 2018-02-26 2021-10-19 Olympic Ophthalmics, Inc. Therapeutic handheld devices for disorders
KR20210018199A (ko) 2018-03-26 2021-02-17 씨4 테라퓨틱스, 인코포레이티드 이카로스의 분해를 위한 세레블론 결합제
EP3806916A1 (en) 2018-06-14 2021-04-21 W.L. Gore & Associates, Inc. Epitheliazing microporous biomaterial for use in avascular environments and in corneal implants
WO2020041301A1 (en) 2018-08-20 2020-02-27 Achillion Pharmaceuticals, Inc. Pharmaceutical compounds for the treatment of complement factor d medical disorders
US11814391B2 (en) 2018-09-06 2023-11-14 Achillion Pharmaceuticals, Inc. Macrocyclic compounds for the treatment of medical disorders
WO2020081723A1 (en) 2018-10-16 2020-04-23 Georgia State University Research Foundation, Inc. Carbon monoxide prodrugs for the treatment of medical disorders
KR20210152515A (ko) 2019-04-12 2021-12-15 씨4 테라퓨틱스, 인코포레이티드 이카로스 및 아이올로스의 트리시클릭 분해제
CA3144406A1 (en) 2019-06-27 2020-12-30 Layerbio, Inc. Ocular device delivery methods and systems
JP2022553408A (ja) 2019-10-24 2022-12-22 デニス・イー・ラボンバード 眼用デバイスおよび薬物送達システムならびにそのケース
US11103446B2 (en) 2019-12-31 2021-08-31 Industrial Technology Research Institute Ophthalmic drug delivery device and method for fabricating the same
CA3166738A1 (en) 2020-02-06 2021-08-12 Charles D. Blizzard Travoprost compositions and methods for treating ocular diseases
US20250197403A1 (en) 2020-02-20 2025-06-19 Achillion Pharmaceuticals, Inc. Heteroaryl compounds for treatment of complement factor d mediated disorders
AU2021231898A1 (en) 2020-03-05 2022-10-27 C4 Therapeutics, Inc. Compounds for targeted degradation of BRD9
CN115701959A (zh) * 2020-04-20 2023-02-14 阿维希有限公司 眼科装置
CA3177005A1 (en) 2020-04-27 2021-11-04 Michael Goldstein Methods of treating allergic conjunctivitis
CN116437913A (zh) 2020-09-23 2023-07-14 艾其林医药公司 用于治疗补体介导的病症的药物化合物
CN114224822B (zh) * 2022-01-28 2023-07-14 复旦大学附属眼耳鼻喉科医院 一种眼部缓释给药植入物及其制造方法
EP4233836B1 (en) * 2022-02-24 2024-11-06 Eyed Pharma Intraocular drug delivery device comprising an eyelet

Family Cites Families (259)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3113076A (en) 1956-07-03 1963-12-03 Henry R Jacobs Medicinal tablets
US3312215A (en) 1963-08-02 1967-04-04 Max N Silber Uterocervical cannula
US3416530A (en) 1966-03-02 1968-12-17 Richard A. Ness Eyeball medication dispensing tablet
US3545439A (en) 1968-01-04 1970-12-08 Upjohn Co Medicated devices and methods
US3566874A (en) 1968-08-13 1971-03-02 Nat Patent Dev Corp Catheter
US3993073A (en) 1969-04-01 1976-11-23 Alza Corporation Novel drug delivery device
US3626940A (en) 1969-05-02 1971-12-14 Alza Corp Ocular insert
US3618604A (en) 1969-06-09 1971-11-09 Alza Corp Ocular insert
US3903880A (en) 1972-08-17 1975-09-09 Alza Corp Intrauterine device for managing the reproductive process
US3760805A (en) 1971-01-13 1973-09-25 Alza Corp Osmotic dispenser with collapsible supply container
US3710796A (en) 1971-05-14 1973-01-16 C Neefe Corneal drug delivery method
US3995635A (en) 1971-09-09 1976-12-07 Alza Corporation Ocular insert
BE788575A (fr) 1971-09-09 1973-01-02 Alza Corp Dispositif oculaire pour l'administration d'un
US3960150A (en) 1971-09-09 1976-06-01 Alza Corporation Bioerodible ocular device
US3828777A (en) 1971-11-08 1974-08-13 Alza Corp Microporous ocular device
US3920805A (en) 1971-12-09 1975-11-18 Upjohn Co Pharmaceutical devices and method
US3826258A (en) 1972-02-07 1974-07-30 S Abraham Gradual release medicine carrier
US3845201A (en) 1972-04-24 1974-10-29 S Loucas Solid state ophthalmic medication delivery method
US3867519A (en) 1972-04-27 1975-02-18 Alza Corp Bioerodible drug delivery device
US3962414A (en) 1972-04-27 1976-06-08 Alza Corporation Structured bioerodible drug delivery device
US4016251A (en) 1972-08-17 1977-04-05 Alza Corporation Vaginal drug dispensing device
US3811444A (en) 1972-12-27 1974-05-21 Alza Corp Bioerodible ocular device
US4177256A (en) 1973-04-25 1979-12-04 Alza Corporation Osmotic bursting drug delivery device
US3916899A (en) 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
US4179497A (en) 1973-12-17 1979-12-18 Merck & Co., Inc. Solid state ophthalmic medication
US3961628A (en) 1974-04-10 1976-06-08 Alza Corporation Ocular drug dispensing system
US3963025A (en) 1974-09-16 1976-06-15 Alza Corporation Ocular drug delivery device
IL48277A (en) 1974-10-18 1978-03-10 Schering Ag Vaginal ring
US4155991A (en) 1974-10-18 1979-05-22 Schering Aktiengesellschaft Vaginal ring
US3926188A (en) 1974-11-14 1975-12-16 Alza Corp Laminated drug dispenser
US4093709A (en) 1975-01-28 1978-06-06 Alza Corporation Drug delivery devices manufactured from poly(orthoesters) and poly(orthocarbonates)
US4131648A (en) 1975-01-28 1978-12-26 Alza Corporation Structured orthoester and orthocarbonate drug delivery devices
ZA761193B (en) 1975-03-19 1977-02-23 Procter & Gamble Controlled release articles
US4014335A (en) 1975-04-21 1977-03-29 Alza Corporation Ocular drug delivery device
US4052505A (en) 1975-05-30 1977-10-04 Alza Corporation Ocular therapeutic system manufactured from copolymer
US4057619A (en) 1975-06-30 1977-11-08 Alza Corporation Ocular therapeutic system with selected membranes for administering ophthalmic drug
NL188266C (nl) 1975-07-29 1992-05-18 Merck & Co Inc Werkwijze ter bereiding van een oogheelkundig inplantaat.
US3991760A (en) 1975-12-02 1976-11-16 The Procter & Gamble Company Vaginal medicament dispensing means
US3995633A (en) 1975-12-02 1976-12-07 The Procter & Gamble Company Vaginal Medicament dispensing device
US3995634A (en) 1975-12-02 1976-12-07 The Procter & Gamble Company Vaginal cavity dispensing means and method
US4008719A (en) 1976-02-02 1977-02-22 Alza Corporation Osmotic system having laminar arrangement for programming delivery of active agent
US4014334A (en) 1976-02-02 1977-03-29 Alza Corporation Laminated osmotic system for dispensing beneficial agent
US4201210A (en) 1976-06-22 1980-05-06 The United States Of America As Represented By The Secretary Of Agriculture Veterinary ocular ring device for sustained drug release
US4164560A (en) 1977-01-05 1979-08-14 Folkman Moses J Systems for the controlled release of macromolecules
US4157864A (en) 1977-02-28 1979-06-12 Friedrich Kilb Contact lens eyeball centering support of soft material for use in conjunction with hard contact lens
US4160452A (en) 1977-04-07 1979-07-10 Alza Corporation Osmotic system having laminated wall comprising semipermeable lamina and microporous lamina
GB1529143A (en) 1977-08-22 1978-10-18 Alza Corp Ocular inserts
US4190642A (en) 1978-04-17 1980-02-26 Alza Corporation Ocular therapeutic system for dispensing a medication formulation
US4215691A (en) 1978-10-11 1980-08-05 Alza Corporation Vaginal contraceptive system made from block copolymer
US4285987A (en) 1978-10-23 1981-08-25 Alza Corporation Process for manufacturing device with dispersion zone
JPS588248B2 (ja) 1978-10-26 1983-02-15 アルザ・コ−ポレ−シヨン 眼科治療装置
US4292965A (en) 1978-12-29 1981-10-06 The Population Council, Inc. Intravaginal ring
US4249531A (en) 1979-07-05 1981-02-10 Alza Corporation Bioerodible system for delivering drug manufactured from poly(carboxylic acid)
US4303637A (en) 1980-04-04 1981-12-01 Alza Corporation Medication indicated for ocular hypertension
US4281654A (en) 1980-04-07 1981-08-04 Alza Corporation Drug delivery system for controlled ocular therapy
US4304765A (en) 1980-10-14 1981-12-08 Alza Corporation Ocular insert housing steroid in two different therapeutic forms
DE3040978A1 (de) 1980-10-28 1982-05-27 Schering Ag, 1000 Berlin Und 4619 Bergkamen Vaginalring
US4322323A (en) 1980-12-01 1982-03-30 Alza Corporation Erodible device comprising surfactant for modifying the rate of erosion of the device
US4484922A (en) 1981-06-25 1984-11-27 Rosenwald Peter L Occular device
US4678466A (en) 1981-06-25 1987-07-07 Rosenwald Peter L Internal medication delivery method and vehicle
US4439198A (en) 1981-07-09 1984-03-27 University Of Illinois Foundation Biodegradable ocular insert for controlled delivery of ophthalmic medication
US4432964A (en) 1981-08-24 1984-02-21 Alza Corporation Topical composition containing steroid in two forms released independently from polymeric carrier
US5248700A (en) 1982-05-14 1993-09-28 Akzo Nv Active agent containing solid structures for prolonged release of active agents
US4961931A (en) 1982-07-29 1990-10-09 Alza Corporation Method for the management of hyperplasia
US4469671A (en) 1983-02-22 1984-09-04 Eli Lilly And Company Contraceptive device
US4540417A (en) 1983-05-02 1985-09-10 Stanley Poler Eye-medicating haptic
JPS59216802A (ja) * 1983-05-20 1984-12-06 Shin Etsu Chem Co Ltd 揮発性物質徐放性製剤
DE3333240A1 (de) 1983-09-12 1985-03-28 Schering AG, 1000 Berlin und 4709 Bergkamen Mittel zur transdermalen applikation von arzneimittelwirkstoffen
US4524776A (en) 1983-10-27 1985-06-25 Withers Stanley J Split carrier for eyelid sensor and the like
GB8403138D0 (en) 1984-02-07 1984-03-14 Graham N B Sustained release of active ingredient
US4652099A (en) 1984-05-30 1987-03-24 Lichtman William M Scleral ring
US5322691A (en) 1986-10-02 1994-06-21 Sohrab Darougar Ocular insert with anchoring protrusions
US5989579A (en) * 1986-10-02 1999-11-23 Escalon Medical Corp. Ocular insert with anchoring protrusions
US5147647A (en) 1986-10-02 1992-09-15 Sohrab Darougar Ocular insert for the fornix
FR2618329B1 (fr) 1987-07-22 1997-03-28 Dow Corning Sa Procede de fabrication d'un anneau capable d'assurer la liberation d'un agent therapeutique, et anneau fabrique par ce procede
US5137728A (en) 1988-03-01 1992-08-11 Bausch & Lomb Incorporated Ophthalmic article
US5098443A (en) 1989-03-23 1992-03-24 University Of Miami Method of implanting intraocular and intraorbital implantable devices for the controlled release of pharmacological agents
ATE167800T1 (de) 1990-04-27 1998-07-15 Allergan Inc Polymeres arzneimittelabgabesystem
JPH05501979A (ja) 1990-05-22 1993-04-15 スティーヴンス フレデリック オスカル 頭部支持枕
US5378475A (en) 1991-02-21 1995-01-03 University Of Kentucky Research Foundation Sustained release drug delivery devices
US5178635A (en) 1992-05-04 1993-01-12 Allergan, Inc. Method for determining amount of medication in an implantable device
US6966927B1 (en) 1992-08-07 2005-11-22 Addition Technology, Inc. Hybrid intrastromal corneal ring
BR9306848A (pt) 1992-08-07 1998-12-08 Keravision Inc Anel polimérico dividido para introdução no estroma
EP0656779B1 (en) 1992-08-28 2000-04-12 Pharmos Corporation Submicron emulsions as ocular drug delivery vehicles
US5972991A (en) 1992-09-21 1999-10-26 Allergan Cyclopentane heptan(ene) oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
US5688819A (en) 1992-09-21 1997-11-18 Allergan Cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
US5352708A (en) 1992-09-21 1994-10-04 Allergan, Inc. Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
US5370607A (en) 1992-10-28 1994-12-06 Annuit Coeptis, Inc. Glaucoma implant device and method for implanting same
US5314419A (en) 1992-10-30 1994-05-24 Pelling George E Method for dispensing ophthalmic drugs to the eye
FI95768C (fi) 1993-06-17 1996-03-25 Leiras Oy Emättimensisäinen antosysteemi
BR9407215A (pt) 1993-08-02 1996-09-17 Keravision Inc Implante corneal intra-estromal pré-formado segmentado
US5443505A (en) 1993-11-15 1995-08-22 Oculex Pharmaceuticals, Inc. Biocompatible ocular implants
JP3720386B2 (ja) 1993-12-27 2005-11-24 住友製薬株式会社 薬物放出制御製剤
US5773021A (en) 1994-03-14 1998-06-30 Vetoquinol S.A. Bioadhesive ophthalmic insert
US5618274A (en) 1994-04-08 1997-04-08 Rosenthal; Kenneth J. Method and device for deep pressurized topical, fornix applied "nerve block" anesthesia
US5472436A (en) 1994-07-26 1995-12-05 Fremstad; Daria A. Ocular appliance for delivering medication
IL116433A (en) 1994-12-19 2002-02-10 Galen Chemicals Ltd INTRAVAGINAL DRUG DELIVERY DEVICES FOR THE ADMINISTRATION OF 17β-OESTRADIOL PRECURSORS
US5605696A (en) 1995-03-30 1997-02-25 Advanced Cardiovascular Systems, Inc. Drug loaded polymeric material and method of manufacture
ES2159734T3 (es) 1995-05-18 2001-10-16 Allergan Sales Inc Derivados 2-heteroarilalquenilicos del acido ciclopentano-heptan(en)oico como agentes terapeuticos para el tratamiento de la hipertension ocular.
US5773019A (en) 1995-09-27 1998-06-30 The University Of Kentucky Research Foundation Implantable controlled release device to deliver drugs directly to an internal portion of the body
FR2745180B1 (fr) 1996-02-23 1998-05-07 Dow Corning Sa Procede de fabrication de dispositifs a liberation controlee
US20090005864A1 (en) 1996-03-18 2009-01-01 Eggleston Harry C Modular intraocular implant
ATE261706T1 (de) 1996-05-17 2004-04-15 Helmut Payer Augenimplantat
US5972372A (en) 1996-07-31 1999-10-26 The Population Council, Inc. Intravaginal rings with insertable drug-containing core
US6120460A (en) 1996-09-04 2000-09-19 Abreu; Marcio Marc Method and apparatus for signal acquisition, processing and transmission for evaluation of bodily functions
US6135118A (en) 1997-05-12 2000-10-24 Dailey; James P. Treatment with magnetic fluids
JP4049411B2 (ja) * 1997-06-27 2008-02-20 株式会社メニコン 硬質コンタクトレンズ用リングおよびそれを用いた硬質コンタクトレンズ複合物
US5902598A (en) 1997-08-28 1999-05-11 Control Delivery Systems, Inc. Sustained release drug delivery devices
AU748653B2 (en) 1998-05-01 2002-06-06 John F. Cline Method for injection molding manufacture of controlled release devices
JP2002518351A (ja) 1998-06-19 2002-06-25 オキシバイオ・インコーポレイテッド 抗感染および避妊特性を有する医療装置
US6146366A (en) 1998-11-03 2000-11-14 Ras Holding Corp Device for the treatment of macular degeneration and other eye disorders
US6361780B1 (en) 1998-11-12 2002-03-26 Cardiac Pacemakers, Inc. Microporous drug delivery system
US6309380B1 (en) 1999-01-27 2001-10-30 Marian L. Larson Drug delivery via conformal film
US6109537A (en) 1999-02-18 2000-08-29 The United States Of America As Represented By The Secretary Of Agriculture Release rate modulator and method for producing and using same
US20040121014A1 (en) 1999-03-22 2004-06-24 Control Delivery Systems, Inc. Method for treating and/or preventing retinal diseases with sustained release corticosteroids
US6217896B1 (en) 1999-04-01 2001-04-17 Uab Research Foundation Conjunctival inserts for topical delivery of medication or lubrication
US6149685A (en) 1999-07-01 2000-11-21 Sigoloff; Bruce Human eye prosthesis
US6485735B1 (en) 1999-08-31 2002-11-26 Phelps Dodge High Performance Conductors Of Sc & Ga, Inc. Multilayer thermoset polymer matrix and structures made therefrom
US6416777B1 (en) 1999-10-21 2002-07-09 Alcon Universal Ltd. Ophthalmic drug delivery device
CA2383499C (en) 1999-10-21 2009-11-24 Alcon Universal Ltd. Drug delivery device
US6264971B1 (en) 1999-11-04 2001-07-24 Btg International Limited Ocular insert
DE60115203T2 (de) 2000-01-24 2006-08-03 Biocompatibles Uk Ltd., Farnham Beschichtete implantate
US7166730B2 (en) 2000-01-27 2007-01-23 Fine Tech Laboratories, Ltd Process for the preparation of prostaglandin derivatives
IL143477A (en) 2001-05-31 2009-07-20 Finetech Pharmaceutical Ltd Process for the preparation of 17-phenyl-18,19,20-trinor-pgf2?? and its derivatives
US6375642B1 (en) 2000-02-15 2002-04-23 Grieshaber & Co. Ag Schaffhausen Method of and device for improving a drainage of aqueous humor within the eye
US6375972B1 (en) 2000-04-26 2002-04-23 Control Delivery Systems, Inc. Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
AU2001271417B2 (en) 2000-08-30 2006-10-05 Johns Hopkins University Devices for intraocular drug delivery
WO2002017883A2 (en) 2000-08-31 2002-03-07 Rtp Pharma Inc. Milled particles
JP2004521882A (ja) 2001-01-03 2004-07-22 ボシュ・アンド・ロム・インコーポレイテッド 組立式透過性プラグを備えた徐放薬剤送達装置
WO2002058667A2 (en) 2001-01-26 2002-08-01 Bausch & Lomb Incorporated Improved process for the production of sustained release drug delivery devices
US20040220660A1 (en) 2001-02-05 2004-11-04 Shanley John F. Bioresorbable stent with beneficial agent reservoirs
NZ528377A (en) 2001-03-27 2005-05-27 Galen Chemicals Ltd Intravaginal drug delivery devices for the administration of an antimicrobial agent
US20050197651A1 (en) 2001-04-25 2005-09-08 Chen Hai L. Vaginal ring preparation and its application
CA2447802C (en) 2001-07-23 2009-09-29 Alcon, Inc. Ophthalmic drug delivery device
DK1385452T3 (da) 2001-07-23 2007-01-15 Alcon Inc Anordning til tilförsel af et ophthalmisk medikament
PT1420716E (pt) 2001-08-29 2012-11-21 Ricardo A P De Carvalho Um sistema implantável e selável destinado à administração unidireccional de agentes terapêuticos em tecidos-alvo
FR2831423B1 (fr) 2001-10-31 2004-10-15 Bausch & Lomb Lentilles intraoculaires munies de rebords anguleux afin d'eviter une opacification capsulaire posterieure
US20030088307A1 (en) 2001-11-05 2003-05-08 Shulze John E. Potent coatings for stents
US7090888B2 (en) 2002-01-18 2006-08-15 Snyder Michael E Sustained release ophthalmological device and method of making and using the same
EP1482914B1 (en) 2002-03-11 2015-04-22 Novartis AG Implantable drug delivery device for the eye
CA2479351C (en) 2002-03-18 2012-05-15 Novartis Ag Topical composition comprising a cyclofructan, a carrier and a drug
EP1494646B2 (en) 2002-03-27 2017-10-04 Warner Chilcott (Ireland) Limited Intravaginal matrix drug delivery devices
US20040115234A1 (en) 2002-09-24 2004-06-17 Gewirtz Joan T. Cosmetic composition
US7785578B2 (en) 2002-10-11 2010-08-31 Aciont, Inc. Non-invasive ocular drug delivery
US6841574B2 (en) 2003-01-03 2005-01-11 Nexmed Holdings, Inc. Topical stabilized prostaglandin E compound dosage forms
US20050048099A1 (en) 2003-01-09 2005-03-03 Allergan, Inc. Ocular implant made by a double extrusion process
EP1603485A4 (en) 2003-02-26 2011-03-30 Medivas Llc BIOACTIVE STENTS AND METHOD OF USE THEREOF
EP1605913A2 (en) 2003-03-21 2005-12-21 Nexmed (Holdings), Inc. Angiogenesis promotion by prostaglandin compositions and methods
ATE461681T1 (de) 2003-04-29 2010-04-15 Gen Hospital Corp Verfahren und vorrichtungen für die verzögerte freisetzung von mehreren arzneimitteln
US8246974B2 (en) 2003-05-02 2012-08-21 Surmodics, Inc. Medical devices and methods for producing the same
AU2004237774B2 (en) 2003-05-02 2009-09-10 Surmodics, Inc. Implantable controlled release bioactive agent delivery device
US20040249364A1 (en) 2003-06-03 2004-12-09 Ilya Kaploun Device and method for dispensing medication to tissue lining a body cavity
US8399013B2 (en) 2003-06-26 2013-03-19 Poly-Med, Inc. Partially absorbable fiber-reinforced composites for controlled drug delivery
US8404272B2 (en) 2003-06-26 2013-03-26 Poly-Med, Inc. Fiber-reinforced composite rings for intravaginal controlled drug delivery
EP1658109B1 (en) 2003-08-26 2014-01-22 Vista Scientific LLC Ocular drug delivery device
US7488343B2 (en) 2003-09-16 2009-02-10 Boston Scientific Scimed, Inc. Medical devices
US20050228482A1 (en) 2003-09-26 2005-10-13 William Herzog Stent covered by a layer having a layer opening
EP1696831B1 (en) 2003-12-05 2014-01-15 Innolene LLC Method of producing a refractive ocular lens
GB0329379D0 (en) 2003-12-19 2004-01-21 Johnson Matthey Plc Prostaglandin synthesis
WO2005072703A2 (en) 2004-01-26 2005-08-11 Control Delivery Systems, Inc. Controlled and sustained delivery of nucleic acid-based therapeutic agents
US20050228473A1 (en) 2004-04-05 2005-10-13 David Brown Device and method for delivering a treatment to an artery
US20050244461A1 (en) 2004-04-30 2005-11-03 Allergan, Inc. Controlled release drug delivery systems and methods for treatment of an eye
US7799336B2 (en) 2004-04-30 2010-09-21 Allergan, Inc. Hypotensive lipid-containing biodegradable intraocular implants and related methods
US8673341B2 (en) 2004-04-30 2014-03-18 Allergan, Inc. Intraocular pressure reduction with intracameral bimatoprost implants
US8128954B2 (en) 2004-06-07 2012-03-06 California Institute Of Technology Biodegradable drug-polymer delivery system
JP2008501806A (ja) 2004-06-08 2008-01-24 オキュラリス ファーマ, インコーポレイテッド 疎水性眼用組成物および使用方法
WO2006002366A2 (en) 2004-06-24 2006-01-05 Surmodics, Inc. Biodegradable ocular devices, methods and systems
WO2006023130A2 (en) 2004-08-12 2006-03-02 Surmodics, Inc. Biodegradable controlled release bioactive agent delivery device
DE05854403T1 (de) * 2004-12-16 2010-08-26 Iscience Interventional Corp., Menlo Park Ophthalmisches implantat zur glaukombehandlung
US20060140867A1 (en) 2004-12-28 2006-06-29 Helfer Jeffrey L Coated stent assembly and coating materials
EP1853221A2 (en) 2005-02-03 2007-11-14 Duramed Pharmaceuticals, Inc. Devices for delivering agents to a vaginal tract
US20060204548A1 (en) 2005-03-01 2006-09-14 Allergan, Inc. Microimplants for ocular administration
DE602006008895D1 (de) 2005-03-04 2009-10-15 Teva Pharma Enzymatische umwandlung eines prostaglandin (bimatoprost)-zwischenproduktes
WO2010102078A1 (en) 2009-03-04 2010-09-10 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
US7851504B2 (en) 2005-03-16 2010-12-14 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
AR050764A1 (es) 2005-03-18 2006-11-22 Maldonado Bas Arturo Anillo intracorneal y el procedimiento para colocarlo
CA2602573C (en) 2005-03-31 2013-10-08 Asahi Glass Co Ltd Protective agent for retinal neuronal cell containing prostaglandin f2 .alpha. derivative as active ingredient
GB2425259B (en) 2005-04-12 2008-09-24 Castex Prod Controlled release devices and structural elements for use in their manufacture
DE112006000921T5 (de) 2005-04-13 2008-05-08 Elan Pharma International Ltd., Athlone Nanopartikuläre Zusammensetzungen zur kontrollierten Freisetzung, die Prostaglandin-Derivate umfassen
US20060235513A1 (en) 2005-04-18 2006-10-19 Price Francis W Jr Corneal implants and methods of use
US7862552B2 (en) 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
US20060292222A1 (en) 2005-06-21 2006-12-28 Matthew Jonasse Drug delivery device having zero or near zero-order release kinetics
ATE425740T1 (de) 2005-09-21 2009-04-15 Univ Aston Chronotherapeutisches okulares abgabesystem aus einer kombination von prostaglandinen und einem betablocker zur behandlung von primarem glaukom
EP1969540A1 (en) 2005-12-05 2008-09-17 Sap Ag Handling exceptional situations in a warehouse management
DE602006020063D1 (de) 2005-12-07 2011-03-24 Univ Ramot Wirkstoffabgebende verbundkörper
US7544371B2 (en) 2005-12-20 2009-06-09 Bausch + Lomb Incorporated Drug delivery systems
JP2007167358A (ja) 2005-12-22 2007-07-05 Taketoshi Suzuki 眼内用の薬剤投与具
EP1973507B1 (en) * 2006-01-17 2011-04-20 Nulens Ltd Intraocular drug dispenser
US20070202150A1 (en) 2006-02-24 2007-08-30 Vipul Dave Implantable device formed from polymer and plasticizer blends
US20070212387A1 (en) 2006-03-08 2007-09-13 Sahajanand Medical Technologies Pvt. Ltd. Coatings for implantable medical devices
BRPI0709344A2 (pt) 2006-03-20 2011-07-12 Duramed Pharmaceuticals Inc anel intravaginal comprimido flexìvel, seu uso e processo de preparação, método de fornecer um agente ativo, kit terapêutico e produto
ES2640458T3 (es) 2006-03-31 2017-11-03 Mati Therapeutics Inc. Implantes del sistema de drenaje nasolagrimal para terapia medicamentosa
WO2007130663A2 (en) 2006-05-04 2007-11-15 Herbert Kaufman Method, device, and system for delivery of therapeutic agents to the eye
US7762662B1 (en) 2006-05-08 2010-07-27 Eno Robert C Colored and ring-patterned contact lenses
GB0613333D0 (en) 2006-07-05 2006-08-16 Controlled Therapeutics Sct Hydrophilic polyurethane compositions
IL177762A0 (en) 2006-08-29 2006-12-31 Arieh Gutman Bimatoprost crystalline form i
US7560489B2 (en) 2006-10-11 2009-07-14 Nexmed Holdings, Inc. Stabilized prostaglandin E composition
US20080097591A1 (en) 2006-10-20 2008-04-24 Biosensors International Group Drug-delivery endovascular stent and method of use
US20080103584A1 (en) 2006-10-25 2008-05-01 Biosensors International Group Temporal Intraluminal Stent, Methods of Making and Using
US7951781B2 (en) 2006-11-02 2011-05-31 University Of Iowa Research Foundation Methods and compositions related to PLUNC surfactant polypeptides
JP5323720B2 (ja) 2006-12-18 2013-10-23 アルコン リサーチ, リミテッド 眼用薬物送達のためのデバイスおよび方法
AU2007339929A1 (en) 2006-12-26 2008-07-10 Qlt Inc. Drug delivery implants for inhibition of optical defects
CN201012180Y (zh) 2007-01-12 2008-01-30 崔浩 结膜囊药物缓释膜
UY30883A1 (es) 2007-01-31 2008-05-31 Alcon Res Tapones punctales y metodos de liberacion de agentes terapeuticos
WO2008113043A1 (en) 2007-03-14 2008-09-18 University Of Washington Device and method for intraocular drug delivery
US20080243095A1 (en) 2007-03-26 2008-10-02 Theta Research Consultants, Llc Method and Apparatus for Ophthalmic Medication Delivery and Ocular Wound Recovery
WO2008151019A1 (en) 2007-05-30 2008-12-11 University Of Florida Research Foundation, Inc. Extended release of bioactive molecules from silicone hydrogels
ES2493641T3 (es) 2007-06-28 2014-09-12 Cydex Pharmaceuticals, Inc. Administración nasal de soluciones acuosas de corticosteroides
CA2698508C (en) 2007-09-07 2017-06-06 Alan R. Rapacki Lacrimal implants and related methods
NZ598483A (en) 2007-09-07 2013-08-30 Quadra Logic Tech Inc Drug cores for sustained release of therapeutic agents
US8741329B2 (en) 2007-09-21 2014-06-03 Merck Sharp & Dohme B.V. Drug delivery system
US7740604B2 (en) 2007-09-24 2010-06-22 Ivantis, Inc. Ocular implants for placement in schlemm's canal
US8974814B2 (en) 2007-11-12 2015-03-10 California Institute Of Technology Layered drug delivery polymer monofilament fibers
US20090143752A1 (en) 2007-12-03 2009-06-04 Higuchi John W Passive intraocular drug delivery devices and associated methods
US20090162417A1 (en) 2007-12-21 2009-06-25 Cook Incorporated Drug eluting ocular conformer
EP3381407A1 (en) 2008-01-03 2018-10-03 Forsight Labs, Llc Intraocular, accomodating lens and methods of use
EP2257250A2 (en) 2008-01-29 2010-12-08 Gilbert H. Kliman Drug delivery devices, kits and methods therefor
BRPI0912182A2 (pt) 2008-05-09 2015-10-06 Qlt Plug Delivery Inc distribuição de liberação prolongada de agentes ativos pára tratar glaucoma e hipertensão ocular
EP2276439A4 (en) 2008-05-12 2013-11-27 Univ Utah Res Found DEVICE AND CORRESPONDING METHODS FOR INTRAOCULAR MEDICAMENT ADMINISTRATION
EP2288333B1 (en) 2008-05-14 2011-12-28 Peter Thomas Roth Labs, Llc Prostaglandin based compositions and method of use thereof
WO2009140345A2 (en) 2008-05-15 2009-11-19 Tate & Lyle Technology Ltd Buffer rinsed sucralose crystals
US8273404B2 (en) 2008-05-19 2012-09-25 Cordis Corporation Extraction of solvents from drug containing polymer reservoirs
EP2135860A1 (en) 2008-06-20 2009-12-23 Sandoz AG Improved process for the production of bimatoprost
TW201012469A (en) 2008-06-24 2010-04-01 Qlt Plug Delivery Inc Combination treatment of glaucoma
US8999945B2 (en) 2008-06-30 2015-04-07 Silenseed Ltd Methods, compositions and systems for local delivery of drugs
US20100040671A1 (en) 2008-08-12 2010-02-18 Ahmed Salah U Intravaginal Devices With a Rigid Support, Methods of Making, and Uses Thereof
WO2010027603A2 (en) 2008-09-03 2010-03-11 Elc Management Llc Compositions comprising solid particles encapsulated in a cross-linked silicone matrix, and methods of making the same
US8932639B2 (en) 2008-09-03 2015-01-13 Elc Management Llc Compositions comprising solid particles encapsulated in a cross-linked silicone matrix, and methods of making the same
US7985208B2 (en) 2008-09-18 2011-07-26 Oasis Research LLC Ring shaped contoured collagen shield for ophthalmic drug delivery
US9095506B2 (en) 2008-11-17 2015-08-04 Allergan, Inc. Biodegradable alpha-2 agonist polymeric implants and therapeutic uses thereof
TWI506333B (zh) 2008-12-05 2015-11-01 Novartis Ag 用以傳遞疏水性舒適劑之眼用裝置及其製造方法
SG173069A1 (en) 2009-01-23 2011-08-29 Quadra Logic Tech Inc Sustained released delivery of one or more agents
WO2010087983A1 (en) 2009-01-29 2010-08-05 Kambiz Thomas Moazed Method and system for effecting changes in pigmented tissue
US9486362B2 (en) 2009-02-10 2016-11-08 Senju Pharmaceutical Co., Ltd. Ring-shaped device
EP2396070B1 (en) 2009-02-12 2024-12-04 Incept Llc Drug delivery through hydrogel plugs
US20100226962A1 (en) 2009-03-03 2010-09-09 Rodstrom Theron R Peri-corneal drug delivery device
US20100233241A1 (en) 2009-03-13 2010-09-16 Vista Scientific Llc Ophthalmic drug delivery system and applications
JP5695035B2 (ja) * 2009-06-03 2015-04-01 フォーサイト・ビジョン5・インコーポレイテッドForsight Vision5,Inc. 前眼部薬物供給
EP2451503B1 (en) * 2009-07-09 2018-10-24 Ivantis, Inc. Ocular implants and methods for delivering ocular implants into the eye
US20120130300A1 (en) 2009-07-14 2012-05-24 Board Of Regents, The Univerity Of Texas System Therapeutic Methods Using Controlled Delivery Devices Having Zero Order Kinetics
WO2011035336A1 (en) 2009-09-21 2011-03-24 Vidus Ocular, Inc. Uveoscleral drainage device
WO2011050638A1 (zh) 2009-11-02 2011-05-05 上海天伟生物制药有限公司 一种比马前列素晶体及其制备方法和用途
PH12012501098A1 (en) 2009-11-23 2014-10-14 Allergan Inc 7-[3,5-dihydroxy-2- (3-hydroxy-5-phenyl-pent-1-enyl)- cyclopentyl]-n-ethyl-hept-5-enamide (bimatoprost) in crystalline form ii, methods for preparation, and methods for use thereof
WO2011075481A1 (en) 2009-12-16 2011-06-23 Allergan, Inc. Intracameral devices for sustained delivery
US8469934B2 (en) 2010-01-27 2013-06-25 Alcon Research, Ltd. Pulsatile peri-corneal drug delivery device
US9028860B2 (en) 2010-04-28 2015-05-12 Poly-Med, Inc. Partially microcellular, selectively hydrophilic composite construct for ocular drug delivery
JP2013526572A (ja) 2010-05-17 2013-06-24 アエリエ・ファーマシューティカルズ・インコーポレーテッド 眼治療薬の送達のための薬物送達装置
WO2012011128A1 (en) 2010-07-23 2012-01-26 Aptuit Laurus Private Limited Preparation of prostaglandin derivatives
SG10201402270WA (en) 2010-08-12 2014-07-30 Univ Nanyang Tech A biodegradable ocular implant
US9370444B2 (en) 2010-10-12 2016-06-21 Emmett T. Cunningham, JR. Subconjunctival conformer device and uses thereof
US20120109054A1 (en) 2010-10-29 2012-05-03 Vista Scientific Llc Devices with an erodible surface for delivering at least one active agent to tissue over a prolonged period of time
WO2012106673A1 (en) 2011-02-04 2012-08-09 Forsight Labs, Llc Intraocular accommodating lens
US20120215184A1 (en) * 2011-02-18 2012-08-23 Valeant International (Barbados) Srl Cylindrical ocular inserts
PL2723714T3 (pl) 2011-06-02 2018-02-28 CHINOIN Zrt. Nowe sposoby otrzymywania amidów prostaglandyn
WO2013040238A2 (en) 2011-09-13 2013-03-21 Vista Scientific Llc Sustained release ocular drug delivery devices and methods of manufacture
ES2912370T3 (es) 2011-09-14 2022-05-25 Forsight Vision5 Inc Aparato para inserción ocular
EP3613413A1 (en) 2011-12-05 2020-02-26 Incept, LLC Medical organogel processes and compositions
CN104884006B (zh) 2012-10-26 2017-12-15 弗赛特影像5股份有限公司 用于持续释放药物到眼睛的眼科系统
EP2978406A1 (en) 2013-03-27 2016-02-03 Forsight Vision5, Inc. Bimatoprost ocular silicone inserts and methods of use thereof

Also Published As

Publication number Publication date
CN104884006A (zh) 2015-09-02
US20180085254A1 (en) 2018-03-29
US10456293B2 (en) 2019-10-29
EP2911623A1 (en) 2015-09-02
JP6298068B2 (ja) 2018-03-20
PT2911623T (pt) 2019-11-21
PL2911623T3 (pl) 2020-03-31
WO2014066775A1 (en) 2014-05-01
CA2888808C (en) 2021-11-09
ES2752028T3 (es) 2020-04-02
JP2015532883A (ja) 2015-11-16
HUE046128T2 (hu) 2020-02-28
US20200222235A1 (en) 2020-07-16
EP2911623B1 (en) 2019-08-14
AU2013334169B2 (en) 2018-03-29
US9750636B2 (en) 2017-09-05
AU2013334169A1 (en) 2015-06-04
US20140121612A1 (en) 2014-05-01
DK2911623T3 (da) 2019-10-28
US20230181356A1 (en) 2023-06-15
CN104884006B (zh) 2017-12-15
RU2652063C2 (ru) 2018-04-24
CA2888808A1 (en) 2014-05-01
RU2015119248A (ru) 2016-12-20

Similar Documents

Publication Publication Date Title
PL2911623T3 (pl) System oczny do przedłużonego uwalniania leku do oka
EP2838511A4 (en) OCULAR MEDICATION DELIVERY SYSTEM
IL227530A (en) A transplantable device for controlled release of a low-solubility drug
PL2836234T3 (pl) Podłoża do kontrolowanego dostarczania różnych środków farmaceutycznych
IL235185A0 (en) mirna modulators of thermogenesis
GB2501109B (en) Actuator for device for delivery of ophthalmic lenses
SG11201405687QA (en) Lens for myopic eye
EP2680741A4 (en) RETINOGRAPH SYSTEM AND METHODOLOGY
ZA201401007B (en) Aminopyrimidine derivative for use as modulators of kinase activity
GB2523055B8 (en) Ophthalmic devices for delivery of beneficial agents
SMT202000021T1 (it) Formulazioni a rilascio prolungato per la somministrazione di proteine nell’occhio e metodi di preparazione delle stesse
EP2906295A4 (en) METHODS OF TREATING OCULAR DISEASES
IL236465B (en) Pharmaceutical composition for delayed release of active substances
GB2502402B (en) Controlled drug release
EP2934403A4 (en) STAMP FOR THE TREATMENT OF EYE DISEASES CONTAINING CLOBETASOL
IL236466A0 (en) Pharmaceutical composition for the release of active components
EP2914258A4 (en) DELAYED RELEASE OF TOPICAL ANESTHETICS
HUE043129T2 (hu) Vakcina intrauterin betegség ellen
EP2934285A4 (en) METHOD AND SYSTEMS FOR DIAGNOSIS OF EYE DISEASES
EP2816985A4 (en) PISTON SYSTEM FOR INTRAOCULAR SURGERY
HUE044183T2 (hu) Kozmetikai ágensek nyújtott felszabadítására szolgáló rendszer
GB2519923B (en) Ophthalmic surgery
PT2704747T (pt) Colírios para tratamento de conjuntivocálase
EP2931113A4 (en) ACTIVE DISCRETE EYE INTERROGATION
GB201317550D0 (en) Use of Enalaprilat for treatment of neurodegenerative diseases