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ES2036561T3 - Un procedimiento para preparar un grupo de compuestos que son acidos 4-hidroxi-4-(alquenil sustituido)ciclohexanocarboxilicos. - Google Patents

Un procedimiento para preparar un grupo de compuestos que son acidos 4-hidroxi-4-(alquenil sustituido)ciclohexanocarboxilicos.

Info

Publication number
ES2036561T3
ES2036561T3 ES198787116316T ES87116316T ES2036561T3 ES 2036561 T3 ES2036561 T3 ES 2036561T3 ES 198787116316 T ES198787116316 T ES 198787116316T ES 87116316 T ES87116316 T ES 87116316T ES 2036561 T3 ES2036561 T3 ES 2036561T3
Authority
ES
Spain
Prior art keywords
compounds
hydroxy
alkyl
cyclohexanocarboxylic
acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787116316T
Other languages
English (en)
Inventor
Robert J. Cregge
Nelsen L. Lentz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Application granted granted Critical
Publication of ES2036561T3 publication Critical patent/ES2036561T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/22—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/55—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing rings other than six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Epoxy Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA INVENCION SE REFIERE A COMPUESTOS DE FORMULA (I), EN LA QUE N ES 0, 1 O 2; R ES UN GRUPO ALQUILO DE CADENA RECTA QUE CONTIENE DE 6 A 15 C; X ES HIDROGENO O CUANDO N ES 1 O 2 X PUEDE SER -NH2; Y ES HIDROXI; O-ALQUILO ( DE 1 A 4 C), NH2, -NH ALQUILO (DE 1 A 4 C), N(ALQUILO)2( DE 1 A 4 C) O -NH-CR''H-COOH (SIENDO R'' HIDROGENO, ALQUILO DE 1 A 4 C O BENCILO); Y Z ES HIDROXI, -O-ALQUILO (DE 1 A 4 C), -NH2, -NH ALQUILO ( DE 1 A 4 C) O N-ALQUILO 2 (DE 1 A 4 C). ESTOS COMPUESTOS SE PUEDEN USAR EN COMPOSICIONES FARMACEUTICAS. SE PUEDEN PREPARAR POR REACCION DE COMPUESTOS DE FORMULA (II), CON COMPUESTOS DE FORMULA (III).
ES198787116316T 1986-11-07 1987-11-05 Un procedimiento para preparar un grupo de compuestos que son acidos 4-hidroxi-4-(alquenil sustituido)ciclohexanocarboxilicos. Expired - Lifetime ES2036561T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/928,759 US4748274A (en) 1986-11-07 1986-11-07 4-hydroxy-4-(substituted alkenyl)cyclohexanecarboxylic acids

Publications (1)

Publication Number Publication Date
ES2036561T3 true ES2036561T3 (es) 1993-06-01

Family

ID=25456699

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787116316T Expired - Lifetime ES2036561T3 (es) 1986-11-07 1987-11-05 Un procedimiento para preparar un grupo de compuestos que son acidos 4-hidroxi-4-(alquenil sustituido)ciclohexanocarboxilicos.

Country Status (21)

Country Link
US (1) US4748274A (es)
EP (1) EP0270843B1 (es)
JP (1) JPH07113011B2 (es)
KR (1) KR950005775B1 (es)
CN (1) CN1009088B (es)
AT (1) ATE61352T1 (es)
AU (1) AU595397B2 (es)
CA (1) CA1296740C (es)
DE (1) DE3768449D1 (es)
DK (1) DK583887A (es)
ES (1) ES2036561T3 (es)
FI (1) FI87923C (es)
GR (1) GR3002075T3 (es)
HU (1) HU197880B (es)
IE (1) IE872998L (es)
IL (1) IL84364A (es)
NO (1) NO167382C (es)
NZ (1) NZ222427A (es)
PH (1) PH24148A (es)
PT (1) PT86093B (es)
ZA (1) ZA878217B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102082304B1 (ko) 2013-05-02 2020-02-27 에스케이케미칼 주식회사 공중합 폴리에스테르 수지 및 이를 이용한 성형제품

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4622422A (en) * 1985-08-23 1986-11-11 Merrell Dow Pharmaceuticals Inc. Cyclohexanealkanoic acids

Also Published As

Publication number Publication date
DK583887A (da) 1988-05-08
IL84364A0 (en) 1988-04-29
PT86093A (en) 1987-12-01
FI874821A7 (fi) 1988-05-08
FI874821A0 (fi) 1987-11-02
ATE61352T1 (de) 1991-03-15
CN1009088B (zh) 1990-08-08
US4748274A (en) 1988-05-31
KR950005775B1 (ko) 1995-05-30
EP0270843A1 (en) 1988-06-15
CN87107599A (zh) 1988-08-03
HUT45475A (en) 1988-07-28
IE872998L (en) 1988-05-07
NO167382C (no) 1991-10-30
NO167382B (no) 1991-07-22
FI87923C (fi) 1993-03-10
DE3768449D1 (en) 1991-04-11
JPS63198660A (ja) 1988-08-17
AU595397B2 (en) 1990-03-29
HU197880B (en) 1989-06-28
AU8060487A (en) 1988-07-28
PT86093B (pt) 1990-11-20
CA1296740C (en) 1992-03-03
DK583887D0 (da) 1987-11-06
EP0270843B1 (en) 1991-03-06
NZ222427A (en) 1989-06-28
JPH07113011B2 (ja) 1995-12-06
FI87923B (fi) 1992-11-30
PH24148A (en) 1990-03-22
NO874627D0 (no) 1987-11-06
KR880006186A (ko) 1988-07-22
ZA878217B (en) 1988-04-28
GR3002075T3 (en) 1992-12-30
IL84364A (en) 1991-08-16
NO874627L (no) 1988-05-09

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