ES2033578A1 - Procedimiento para la obtencion de 3-(2-(dimetilamino)etil)-n-metil-1h-indol-5-metanosulfonamida. - Google Patents
Procedimiento para la obtencion de 3-(2-(dimetilamino)etil)-n-metil-1h-indol-5-metanosulfonamida.Info
- Publication number
- ES2033578A1 ES2033578A1 ES919101360A ES9101360A ES2033578A1 ES 2033578 A1 ES2033578 A1 ES 2033578A1 ES 919101360 A ES919101360 A ES 919101360A ES 9101360 A ES9101360 A ES 9101360A ES 2033578 A1 ES2033578 A1 ES 2033578A1
- Authority
- ES
- Spain
- Prior art keywords
- methyl
- amino
- ethyl
- prepn
- sulphonyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003054 catalyst Substances 0.000 abstract 1
- 238000006114 decarboxylation reaction Methods 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Landscapes
- Indole Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE 3-[2-(DIMETILAMINO)ETIL]-N-METIL-1H-INDOL-5-METANOSULFONAMIDA. CONSISTE EN LA DESCARBOXILACION DE LA 2-CARBOXI-3-[2-(DIMETILAMINO)ETIL]-N-METIL-1H-INDOL-5-METANOSULFONAMIDA (FORMULA II), EN PRESENCIA DE UN DISOLVENTE Y DE UN CATALIZADOR ADECUADOS, EN ATMOSFERA INERTE Y A UNA TEMPERATURA ENTRE 190GC Y 250GC, PARA OBTENER LA 3-[2-(DIMETILAMINO)ETIL-N-METIL-1H-INDOL-5-METANO-SULFONAMIDA (FORMULA I), CUYAS SALES Y SOLVATOS SON UTILES EN EL TRATAMIENTO DE LA MIGRAÑA.
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES09101360A ES2033578B1 (es) | 1991-06-06 | 1991-06-06 | Procedimiento para la obtencion de 3-(2-(dimetilamino)etil)-n-metil-1h-indol-5-metanosulfonamida. |
| NO930443A NO300589B1 (no) | 1991-06-06 | 1993-02-09 | Fremgangsmåte for fremstilling av 3-£2-(dimetylamino)-etyl|-N-metyl-1H-indol-5-metansulfonamid |
| PT10119893A PT101198B (pt) | 1991-06-06 | 1993-02-12 | Processo para a obtencao de 3-{2-(dimetilamino)etil}-n-metil-1h-indol-5-metanossulfonamida |
| CZ93197A CZ283683B6 (cs) | 1991-06-06 | 1993-02-15 | Způsob výroby 3-[2-(dimethylamino)ethyl]-N-methyl-1H-indol-5-methansulfonamidu |
| AT27593A AT399870B (de) | 1991-06-06 | 1993-02-15 | Verfahren zur herstellung von 3-(2-(dimethylamino)ethyl)-n-methyl-1h-indol-5- ethansulfonamid |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES09101360A ES2033578B1 (es) | 1991-06-06 | 1991-06-06 | Procedimiento para la obtencion de 3-(2-(dimetilamino)etil)-n-metil-1h-indol-5-metanosulfonamida. |
| CZ93197A CZ283683B6 (cs) | 1991-06-06 | 1993-02-15 | Způsob výroby 3-[2-(dimethylamino)ethyl]-N-methyl-1H-indol-5-methansulfonamidu |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2033578A1 true ES2033578A1 (es) | 1993-03-16 |
| ES2033578B1 ES2033578B1 (es) | 1995-01-16 |
Family
ID=25746855
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES09101360A Expired - Fee Related ES2033578B1 (es) | 1991-06-06 | 1991-06-06 | Procedimiento para la obtencion de 3-(2-(dimetilamino)etil)-n-metil-1h-indol-5-metanosulfonamida. |
Country Status (2)
| Country | Link |
|---|---|
| CZ (1) | CZ283683B6 (es) |
| ES (1) | ES2033578B1 (es) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2056025A1 (es) * | 1992-10-08 | 1994-09-16 | Almirall Lab | Nuevos derivados de indol. |
| WO2004014877A1 (en) * | 2002-08-07 | 2004-02-19 | Vita Cientifica, S.L. | Process for preparing rizatriptan |
| WO2004099140A1 (en) * | 2003-05-08 | 2004-11-18 | Hetero Drugs Limited | Novel crystalline forms of sumatriptan succinate |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2084560B1 (es) * | 1994-03-09 | 1997-01-16 | Almirall Lab | Procedimiento de preparacion de derivados el indol. |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2081717A (en) * | 1980-08-12 | 1982-02-24 | Glaxo Group Ltd | Hereocyclic compounds |
| EP0145459A2 (en) * | 1983-12-06 | 1985-06-19 | Glaxo Group Limited | Process for the production of chemical compounds |
| EP0147107A1 (en) * | 1983-12-06 | 1985-07-03 | Glaxo Group Limited | Indole derivates |
-
1991
- 1991-06-06 ES ES09101360A patent/ES2033578B1/es not_active Expired - Fee Related
-
1993
- 1993-02-15 CZ CZ93197A patent/CZ283683B6/cs not_active IP Right Cessation
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2081717A (en) * | 1980-08-12 | 1982-02-24 | Glaxo Group Ltd | Hereocyclic compounds |
| EP0145459A2 (en) * | 1983-12-06 | 1985-06-19 | Glaxo Group Limited | Process for the production of chemical compounds |
| EP0147107A1 (en) * | 1983-12-06 | 1985-07-03 | Glaxo Group Limited | Indole derivates |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2056025A1 (es) * | 1992-10-08 | 1994-09-16 | Almirall Lab | Nuevos derivados de indol. |
| WO2004014877A1 (en) * | 2002-08-07 | 2004-02-19 | Vita Cientifica, S.L. | Process for preparing rizatriptan |
| ES2204303A1 (es) * | 2002-08-07 | 2004-04-16 | Laboratorios Vita, S.A. | Procedimiento para la obtencion de un compuesto farmaceuticamente activo. |
| US7279581B2 (en) | 2002-08-07 | 2007-10-09 | Inke, S.A. | Process for preparing a pharmaceutically active compound |
| WO2004099140A1 (en) * | 2003-05-08 | 2004-11-18 | Hetero Drugs Limited | Novel crystalline forms of sumatriptan succinate |
Also Published As
| Publication number | Publication date |
|---|---|
| CZ283683B6 (cs) | 1998-06-17 |
| ES2033578B1 (es) | 1995-01-16 |
| CZ19793A3 (en) | 1994-08-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GC2A | Exploitation certificate registered application with search report |
Effective date: 19970415 |
|
| FD2A | Announcement of lapse in spain |
Effective date: 20111201 |